WO2009063991A1 - ピリドオキサゼピン誘導体およびその用途 - Google Patents

ピリドオキサゼピン誘導体およびその用途 Download PDF

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Publication number
WO2009063991A1
WO2009063991A1 PCT/JP2008/070808 JP2008070808W WO2009063991A1 WO 2009063991 A1 WO2009063991 A1 WO 2009063991A1 JP 2008070808 W JP2008070808 W JP 2008070808W WO 2009063991 A1 WO2009063991 A1 WO 2009063991A1
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WIPO (PCT)
Prior art keywords
pyridooxazepine
derivative
optionally substituted
compound represented
formula
Prior art date
Application number
PCT/JP2008/070808
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English (en)
French (fr)
Inventor
Takahiro Matsumoto
Tomokazu Kusumoto
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Takeda Pharmaceutical Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Takeda Pharmaceutical Company Limited filed Critical Takeda Pharmaceutical Company Limited
Priority to US12/742,837 priority Critical patent/US8329687B2/en
Priority to JP2009541193A priority patent/JP5361733B2/ja
Priority to EP08849982.7A priority patent/EP2213675B1/en
Publication of WO2009063991A1 publication Critical patent/WO2009063991A1/ja

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    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
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Abstract

　本発明は、優れたセロトニン５－ＨＴ２Ｃ受容体活性化作用を有する下式化合物を提供する： 式  〔式中、Ａは、－ＯＲ１または－Ｓ（Ｏ）ｐＲ２を示し、Ｒ１およびＲ２は、それぞれ水素原子、置換基を有していてもよい炭化水素基、または置換基を有していてもよい複素環基を示し、ｐは０、１または２を示す。〕で表される化合物またはその塩。
PCT/JP2008/070808 2007-11-15 2008-11-14 ピリドオキサゼピン誘導体およびその用途 WO2009063991A1 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US12/742,837 US8329687B2 (en) 2007-11-15 2008-11-14 Pyridooxazepine derivative and use thereof
JP2009541193A JP5361733B2 (ja) 2007-11-15 2008-11-14 ピリドオキサゼピン誘導体およびその用途
EP08849982.7A EP2213675B1 (en) 2007-11-15 2008-11-14 Pyridooxazepine derivative and use thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-297169 2007-11-15
JP2007297169 2007-11-15

Publications (1)

Publication Number Publication Date
WO2009063991A1 true WO2009063991A1 (ja) 2009-05-22

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PCT/JP2008/070808 WO2009063991A1 (ja) 2007-11-15 2008-11-14 ピリドオキサゼピン誘導体およびその用途

Country Status (4)

Country Link
US (1) US8329687B2 (ja)
EP (1) EP2213675B1 (ja)
JP (1) JP5361733B2 (ja)
WO (1) WO2009063991A1 (ja)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010147226A1 (en) * 2009-06-15 2010-12-23 Takeda Pharmaceutical Company Limited Pyrazinooxazepine derivatives
US8916549B2 (en) 2009-08-04 2014-12-23 Takeda Pharmaceutical Company Limited Thienooxazepine derivative
WO2015066344A1 (en) 2013-11-01 2015-05-07 Arena Pharmaceuticals, Inc. 5-ht2c receptor agonists and compositions and methods of use
CN105441958A (zh) * 2015-11-27 2016-03-30 重庆大学 含两个苯并三氮唑环的缓蚀剂的合成与应用
WO2017026538A1 (en) 2015-08-07 2017-02-16 Takeda Pharmaceutical Company Limited Production method of pyrazine

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007132841A1 (ja) * 2006-05-16 2007-11-22 Takeda Pharmaceutical Company Limited 縮合複素環化合物およびその用途
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