WO2009063993A1 - 縮合ピリジン誘導体およびその用途 - Google Patents
縮合ピリジン誘導体およびその用途 Download PDFInfo
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- WO2009063993A1 WO2009063993A1 PCT/JP2008/070810 JP2008070810W WO2009063993A1 WO 2009063993 A1 WO2009063993 A1 WO 2009063993A1 JP 2008070810 W JP2008070810 W JP 2008070810W WO 2009063993 A1 WO2009063993 A1 WO 2009063993A1
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- Prior art keywords
- pyridine derivative
- fused pyridine
- formula
- fused
- serotonin
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- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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- C07D513/04—Ortho-condensed systems
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Abstract
本発明は、式:
[式中、各記号は明細書中と同義を示す]で表される化合物またはその塩を含有してなるセロトニン5-HT2c受容体活性化剤に関する。
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JP2007297265 | 2007-11-15 | ||
JP2007-297265 | 2007-11-15 |
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WO2009063993A1 true WO2009063993A1 (ja) | 2009-05-22 |
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Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010147226A1 (en) * | 2009-06-15 | 2010-12-23 | Takeda Pharmaceutical Company Limited | Pyrazinooxazepine derivatives |
WO2011105611A1 (ja) * | 2010-02-26 | 2011-09-01 | ラクオリア創薬株式会社 | 悪液質を治療するためのグレリン受容体作動物質 |
US8916549B2 (en) | 2009-08-04 | 2014-12-23 | Takeda Pharmaceutical Company Limited | Thienooxazepine derivative |
WO2015066344A1 (en) | 2013-11-01 | 2015-05-07 | Arena Pharmaceuticals, Inc. | 5-ht2c receptor agonists and compositions and methods of use |
WO2016089797A1 (en) | 2014-12-05 | 2016-06-09 | Merck Sharp & Dohme Corp. | Novel tricyclic compounds as inhibitors of mutant idh enzymes |
WO2017026538A1 (en) | 2015-08-07 | 2017-02-16 | Takeda Pharmaceutical Company Limited | Production method of pyrazine |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2004096196A2 (en) * | 2003-04-25 | 2004-11-11 | Pfizer Limited | Treatment of incontinence with 5htc2 agonists |
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2008
- 2008-11-14 WO PCT/JP2008/070810 patent/WO2009063993A1/ja active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004096196A2 (en) * | 2003-04-25 | 2004-11-11 | Pfizer Limited | Treatment of incontinence with 5htc2 agonists |
Non-Patent Citations (2)
Title |
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CARBONI, S. ET AL.: "PREPARAZIONE DI ALCUNE PIRIDO[2,3-e]-1,4-DIAZEPINE", FARMACO-EDIZIONE SCIENTIFICA, vol. 31, no. 5, 1976, pages 322 - 333 * |
CARBONI, S. ET AL.: "SINTESI ED ATTIVITA BIOLOGICA DI PIRIDO[2,3-e]-1,4-DIAZEPINE E DI PIRIDO[2,3-b][1,4]DIAZEPINE", FARMACO-EDIZIONE SCIENTIFICA, vol. 30, no. 4, 1975, pages 237 - 247 * |
Cited By (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010147226A1 (en) * | 2009-06-15 | 2010-12-23 | Takeda Pharmaceutical Company Limited | Pyrazinooxazepine derivatives |
US9115139B2 (en) | 2009-06-15 | 2015-08-25 | Takeda Pharmaceutical Company Limited | Pyrazinooxazepine derivatives |
JP2012107032A (ja) * | 2009-06-15 | 2012-06-07 | Takeda Chem Ind Ltd | ピラジノオキサゼピン誘導体 |
US8314088B2 (en) | 2009-06-15 | 2012-11-20 | Takeda Pharmaceutical Company Limited | Pyrazinooxazepine derivatives |
US8318722B2 (en) | 2009-06-15 | 2012-11-27 | Takeda Pharmaceutical Company Limited | Pyrazinooxazepine derivatives |
JP2012530051A (ja) * | 2009-06-15 | 2012-11-29 | 武田薬品工業株式会社 | ピラジノオキサゼピン誘導体 |
US8324201B2 (en) | 2009-06-15 | 2012-12-04 | Takeda Pharmaceutical Company Limited | Pyrazinooxazepine derivatives |
EA021079B1 (ru) * | 2009-06-15 | 2015-03-31 | Такеда Фармасьютикал Компани Лимитед | Производные пиразинооксазепина |
US8916549B2 (en) | 2009-08-04 | 2014-12-23 | Takeda Pharmaceutical Company Limited | Thienooxazepine derivative |
JPWO2011105611A1 (ja) * | 2010-02-26 | 2013-06-20 | ラクオリア創薬株式会社 | 悪液質を治療するためのグレリン受容体作動物質 |
WO2011105611A1 (ja) * | 2010-02-26 | 2011-09-01 | ラクオリア創薬株式会社 | 悪液質を治療するためのグレリン受容体作動物質 |
US10975070B2 (en) | 2010-02-26 | 2021-04-13 | Raqualia Pharma Inc. | Ghrelin receptor agonist for treatment of cachexia |
WO2015066344A1 (en) | 2013-11-01 | 2015-05-07 | Arena Pharmaceuticals, Inc. | 5-ht2c receptor agonists and compositions and methods of use |
WO2016089797A1 (en) | 2014-12-05 | 2016-06-09 | Merck Sharp & Dohme Corp. | Novel tricyclic compounds as inhibitors of mutant idh enzymes |
EP3226688A4 (en) * | 2014-12-05 | 2018-09-26 | Merck Sharp & Dohme Corp. | Novel tricyclic compounds as inhibitors of mutant idh enzymes |
US10442819B2 (en) | 2014-12-05 | 2019-10-15 | Merck Sharp & Dohme Corp. | Tricyclic compounds as inhibitors of mutant IDH enzymes |
WO2017026538A1 (en) | 2015-08-07 | 2017-02-16 | Takeda Pharmaceutical Company Limited | Production method of pyrazine |
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