WO2009005123A1 - インターフェロンβ産生促進剤及びその製造法 - Google Patents

インターフェロンβ産生促進剤及びその製造法 Download PDF

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Publication number
WO2009005123A1
WO2009005123A1 PCT/JP2008/062065 JP2008062065W WO2009005123A1 WO 2009005123 A1 WO2009005123 A1 WO 2009005123A1 JP 2008062065 W JP2008062065 W JP 2008062065W WO 2009005123 A1 WO2009005123 A1 WO 2009005123A1
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WO
WIPO (PCT)
Prior art keywords
interferon
production
production promoter
lactic acid
acid bacterium
Prior art date
Application number
PCT/JP2008/062065
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English (en)
French (fr)
Inventor
Tadaomi Kawashima
Daisuke Kaneko
Ikuko Masuda
Noriko Tsuji
Akemi Kosaka
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Kikkoman Corporation
National Institute Of Advanced Industrial Science And Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Kikkoman Corporation, National Institute Of Advanced Industrial Science And Technology filed Critical Kikkoman Corporation
Priority to US12/452,414 priority Critical patent/US20110256611A1/en
Priority to JP2009521667A priority patent/JP5312322B2/ja
Publication of WO2009005123A1 publication Critical patent/WO2009005123A1/ja

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/065—Microorganisms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Pulmonology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

　インターフェロンβ産生促進剤及びその製造法の提供。 　乳酸菌の培養物、菌体又は菌体成分を有効成分とするインターフェロンβ産生促進剤。菌体成分としてはＲＮＡが使用できる。また乳酸菌としてはラクトバチルス属、テトラジェノコッカス属、ペディオコッカス属又はストレプトコッカス属に属するものが使用できる。インターフェロンβ産生促進剤は、乳酸菌を培養し、培養物、菌体又は菌体成分を採取することにより製造することができる。
PCT/JP2008/062065 2007-04-03 2008-07-03 インターフェロンβ産生促進剤及びその製造法 WO2009005123A1 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US12/452,414 US20110256611A1 (en) 2007-04-03 2008-07-03 Interferon beta production promoter and a method for producing thereof
JP2009521667A JP5312322B2 (ja) 2007-07-03 2008-07-03 インターフェロンβ産生促進剤及びその製造法

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2007-174694 2007-04-03
JP2007174694 2007-07-03
JP2007299242 2007-11-19
JP2007-299242 2007-11-19

Publications (1)

Publication Number Publication Date
WO2009005123A1 true WO2009005123A1 (ja) 2009-01-08

Family

ID=40226164

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/062065 WO2009005123A1 (ja) 2007-04-03 2008-07-03 インターフェロンβ産生促進剤及びその製造法

Country Status (3)

Country Link
US (1) US20110256611A1 (ja)
JP (1) JP5312322B2 (ja)
WO (1) WO2009005123A1 (ja)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2009005124A1 (ja) * 2007-07-04 2010-08-26 キッコーマン株式会社 乳酸菌由来の２本鎖ｒｎａ
WO2011027829A1 (ja) * 2009-09-02 2011-03-10 京都府公立大学法人 乳酸菌由来のｒｎａを有効成分とする組成物
JP2015092841A (ja) * 2013-11-11 2015-05-18 キッコーマン株式会社 経口免疫寛容増強物質のスクリーニング方法および経口免疫寛容増強組成物
JP2016073314A (ja) * 2010-12-28 2016-05-12 キリンホールディングス株式会社 乳酸菌を含むインターフェロン産生誘導剤
JP2018048087A (ja) * 2016-09-21 2018-03-29 アダプトゲン製薬株式会社 体重又は内臓脂肪増加抑制剤若しくは体重又は内臓脂肪増加抑制用食品組成物若しくは体重又は内臓脂肪増加抑制用飼料組成物
WO2018207924A1 (ja) * 2017-05-12 2018-11-15 キッコーマン株式会社 二本鎖ｒｎａ高含有乳酸菌の製造方法及び該乳酸菌

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11260085B2 (en) 2016-09-12 2022-03-01 Ichibiki Co., Ltd. Salt-tolerant lactobacillus, method of culturing salt-tolerant lactobacillus, and immunostimulant

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JPH09124496A (ja) * 1995-10-31 1997-05-13 Nichinichi Seiyaku Kk 感染防御剤
WO2005115420A1 (en) * 2004-05-28 2005-12-08 Suntory Limited A composition having immunoregulating activities comprising lactobacillus pentosus

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JPH08242763A (ja) * 1995-03-10 1996-09-24 Morishita Jintan Kk カプセル化された腸内有用細菌を含有するヨーグルト
JPH10139674A (ja) * 1996-11-11 1998-05-26 Yakult Honsha Co Ltd インターロイキン１２産生促進剤
JP2004024248A (ja) * 2002-05-02 2004-01-29 Yamasa Shoyu Co Ltd 本醸造淡色醤油及びその製法
JP2005333898A (ja) * 2004-05-27 2005-12-08 Otsuka Shokuhin Kk 炭酸入り乳酸発酵飲料の製造方法
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JPH09124496A (ja) * 1995-10-31 1997-05-13 Nichinichi Seiyaku Kk 感染防御剤
WO2005115420A1 (en) * 2004-05-28 2005-12-08 Suntory Limited A composition having immunoregulating activities comprising lactobacillus pentosus

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KITAZAWA H. ET AL.: "INTERFERON INDUCTION IN MURINE PERITONEAL MACROPHAGE BY STIMULATION WITH LACTOBACILLUS-ACIDOPHILUS", MICROBIOLOGY AND IMMUNOLOGY, vol. 36, no. 3, 1992, pages 311 - 315 *
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Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2009005124A1 (ja) * 2007-07-04 2010-08-26 キッコーマン株式会社 乳酸菌由来の２本鎖ｒｎａ
JP5099649B2 (ja) * 2007-07-04 2012-12-19 キッコーマン株式会社 乳酸菌由来の２本鎖ｒｎａ
WO2011027829A1 (ja) * 2009-09-02 2011-03-10 京都府公立大学法人 乳酸菌由来のｒｎａを有効成分とする組成物
JPWO2011027829A1 (ja) * 2009-09-02 2013-02-04 京都府公立大学法人 乳酸菌由来のｒｎａを有効成分とする組成物
US8765706B2 (en) 2009-09-02 2014-07-01 Kyoto Prefectural Public University Corporation Composition comprising rna derived from lactic acid bacterium as effective component
JP5690270B2 (ja) * 2009-09-02 2015-03-25 京都府公立大学法人 乳酸菌由来のｒｎａを有効成分とする組成物
US9549956B2 (en) 2010-12-28 2017-01-24 Kirin Holdings Kabushiki Kaisha Agent for inducing interferon production containing lactic acid bacteria
JP2016073314A (ja) * 2010-12-28 2016-05-12 キリンホールディングス株式会社 乳酸菌を含むインターフェロン産生誘導剤
JP2017201984A (ja) * 2010-12-28 2017-11-16 キリンホールディングス株式会社 乳酸菌を含むインターフェロン産生誘導剤
US10220060B2 (en) 2010-12-28 2019-03-05 Kirin Holdings Kabushiki Kaisha Agent for inducing interferon production containing lactic acid bacteria
US11224623B2 (en) 2010-12-28 2022-01-18 Kirin Holdings Kabushiki Kaisha Agent for inducing interferon production containing lactic acid bacteria
US11944657B2 (en) 2010-12-28 2024-04-02 Kirin Holdings Kabushiki Kaisha Agent for inducing interferon production containing lactic acid bacteria
JP2015092841A (ja) * 2013-11-11 2015-05-18 キッコーマン株式会社 経口免疫寛容増強物質のスクリーニング方法および経口免疫寛容増強組成物
JP2018048087A (ja) * 2016-09-21 2018-03-29 アダプトゲン製薬株式会社 体重又は内臓脂肪増加抑制剤若しくは体重又は内臓脂肪増加抑制用食品組成物若しくは体重又は内臓脂肪増加抑制用飼料組成物
WO2018207924A1 (ja) * 2017-05-12 2018-11-15 キッコーマン株式会社 二本鎖ｒｎａ高含有乳酸菌の製造方法及び該乳酸菌
JP6480090B1 (ja) * 2017-05-12 2019-03-06 キッコーマン株式会社 二本鎖ｒｎａ高含有乳酸菌の製造方法及び該乳酸菌
US11518976B2 (en) 2017-05-12 2022-12-06 Kikkoman Corporation Method for producing double-stranded RNA-rich lactic acid bacterium, and said lactic acid bacterium

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Publication number Publication date
JP5312322B2 (ja) 2013-10-09
US20110256611A1 (en) 2011-10-20
JPWO2009005123A1 (ja) 2010-08-26

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