WO2008111562A1 - 美白剤 - Google Patents

美白剤 Download PDF

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Publication number
WO2008111562A1
WO2008111562A1 PCT/JP2008/054313 JP2008054313W WO2008111562A1 WO 2008111562 A1 WO2008111562 A1 WO 2008111562A1 JP 2008054313 W JP2008054313 W JP 2008054313W WO 2008111562 A1 WO2008111562 A1 WO 2008111562A1
Authority
WO
WIPO (PCT)
Prior art keywords
less
whitening agent
whitening
antigenicity
kda
Prior art date
Application number
PCT/JP2008/054313
Other languages
English (en)
French (fr)
Inventor
Tatsuya Watanabe
Ken Kato
Hiroshi Ueno
Yuko Haruta
Noriko Ueda
Toshimitsu Yoshioka
Original Assignee
Snow Brand Milk Products Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Snow Brand Milk Products Co., Ltd. filed Critical Snow Brand Milk Products Co., Ltd.
Priority to CA2680544A priority Critical patent/CA2680544C/en
Priority to CN2008800057958A priority patent/CN101616657B/zh
Priority to EP08721729A priority patent/EP2138159A4/en
Priority to AU2008225531A priority patent/AU2008225531B2/en
Priority to NZ579687A priority patent/NZ579687A/xx
Priority to US12/530,617 priority patent/US9173902B2/en
Publication of WO2008111562A1 publication Critical patent/WO2008111562A1/ja
Priority to HK10104616.4A priority patent/HK1137151A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/20—Milk; Whey; Colostrum
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
    • A23C9/1526—Amino acids; Peptides; Protein hydrolysates; Nucleic acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/142—Amino acids; Derivatives thereof
    • A23K20/147—Polymeric derivatives, e.g. peptides or proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/19—Dairy proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
    • A61K38/018—Hydrolysed proteins; Derivatives thereof from animals from milk
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/92—Oral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Nutrition Science (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Animal Husbandry (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Non-Alcoholic Beverages (AREA)
  • Fodder In General (AREA)

Abstract

　分子量分布が10kDa以下でメインピーク200Da～3kDa、APL（平均ペプチド鎖長）は２～８、遊離アミノ酸含量20％以下、及び抗原性が、β－ラクトグロブリンの抗原性の１／10,000以下である特徴を有するホエータンパク加水分解物を有効成分として含有する皮膚の美白効果に優れ、シミ、ソバカス等の予防及び治療に有効な美白剤及び該美白剤を含有する化粧品、飲食品、飼料、医薬等の美白製品。
PCT/JP2008/054313 2007-03-13 2008-03-10 美白剤 WO2008111562A1 (ja)

Priority Applications (7)

Application Number Priority Date Filing Date Title
CA2680544A CA2680544C (en) 2007-03-13 2008-03-10 Skin-whitening agent
CN2008800057958A CN101616657B (zh) 2007-03-13 2008-03-10 美白剂
EP08721729A EP2138159A4 (en) 2007-03-13 2008-03-10 BLEACH
AU2008225531A AU2008225531B2 (en) 2007-03-13 2008-03-10 Whitening agent
NZ579687A NZ579687A (en) 2007-03-13 2008-03-10 Whitening agent
US12/530,617 US9173902B2 (en) 2007-03-13 2008-03-10 Skin-whitening agent
HK10104616.4A HK1137151A1 (en) 2007-03-13 2010-05-11 Whitening agent

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2007-063053 2007-03-13
JP2007063053 2007-03-13
JP2007-299516 2007-11-19
JP2007299516A JP5274814B2 (ja) 2007-03-13 2007-11-19 美白剤

Publications (1)

Publication Number Publication Date
WO2008111562A1 true WO2008111562A1 (ja) 2008-09-18

Family

ID=39759497

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/054313 WO2008111562A1 (ja) 2007-03-13 2008-03-10 美白剤

Country Status (10)

Country Link
US (1) US9173902B2 (ja)
EP (1) EP2138159A4 (ja)
JP (1) JP5274814B2 (ja)
KR (1) KR101555067B1 (ja)
CN (1) CN101616657B (ja)
AU (1) AU2008225531B2 (ja)
CA (1) CA2680544C (ja)
HK (1) HK1137151A1 (ja)
NZ (1) NZ579687A (ja)
WO (1) WO2008111562A1 (ja)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010073531A1 (ja) * 2008-12-24 2010-07-01 雪印乳業株式会社 筋肉増強剤
WO2011046101A1 (ja) 2009-10-13 2011-04-21 雪印乳業株式会社 脂肪蓄積抑制剤
WO2011099548A1 (ja) 2010-02-12 2011-08-18 雪印乳業株式会社 タンパク質合成促進剤
WO2011108692A1 (ja) 2010-03-04 2011-09-09 雪印乳業株式会社 筋肉萎縮防止剤
EP2420244A1 (en) * 2009-04-16 2012-02-22 Megmilk Snow Brand Co., Ltd. Lipid metabolism-improving agent
WO2012121286A1 (ja) * 2011-03-10 2012-09-13 雪印メグミルク株式会社 美肌剤

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5410179B2 (ja) * 2009-07-08 2014-02-05 花王株式会社 苦味抑制剤
SG185410A1 (en) * 2010-05-21 2012-12-28 Meiji Co Ltd Composition for improving condition of skin
JP5890100B2 (ja) 2011-02-09 2016-03-22 雪印メグミルク株式会社 皮膚コラーゲン産生促進剤
US9023327B2 (en) * 2012-08-30 2015-05-05 Avon Products, Inc. DICKKOPF-1 expression modulating compositions and uses thereof
CN105287274A (zh) * 2015-10-09 2016-02-03 湖北穆兰同大科技有限公司 莲子芯金银花蜜控油凝乳及其制备方法
CN105168069A (zh) * 2015-10-16 2015-12-23 湖北穆兰同大科技有限公司 一种含有莲子芯金银花的保湿净肤水及其制备方法
CN108588156A (zh) * 2018-04-24 2018-09-28 浙江大学 一种水牛乳酪蛋白抗氧化活性肽的制备方法

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02138991A (ja) 1988-11-19 1990-05-28 Morinaga Milk Ind Co Ltd 低分子量ペプチド組成物およびその製造方法
JPH0469315A (ja) 1990-07-09 1992-03-04 Morinaga Milk Ind Co Ltd チロシナーゼ活性阻害剤
JPH04112753A (ja) 1990-08-31 1992-04-14 Snow Brand Milk Prod Co Ltd 低アレルゲン化したホエータンパク加水分解物及びその製造法
JPH04187619A (ja) * 1990-11-22 1992-07-06 Nonogawa Shoji Kk メラニン生成抑制剤および化粧料
JPH05209000A (ja) * 1991-12-27 1993-08-20 Snow Brand Milk Prod Co Ltd 低アレルゲン化ペプチド組成物
JPH07252126A (ja) * 1994-03-11 1995-10-03 Momotani Jiyuntenkan:Kk 美白化粧料
JPH0898656A (ja) * 1994-09-30 1996-04-16 Snow Brand Milk Prod Co Ltd ホエータンパク質ペプチド組成物及びその製造法
JPH0930928A (ja) * 1995-07-24 1997-02-04 Nitsusen Kagaku Kk 特定成分からなる乳清（ラクトスキン）含有の皮膚化粧料
JPH10218755A (ja) * 1997-02-07 1998-08-18 Morinaga Milk Ind Co Ltd メラニン産生抑制剤

Family Cites Families (5)

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EP0321603A1 (fr) * 1987-12-23 1989-06-28 Societe Des Produits Nestle S.A. Procédé de préparation d'un hydrolysat de protéines de lactosérum et d'un aliment hypoallergéniques
US5219838A (en) * 1990-07-09 1993-06-15 Morinaga Milk Industry Co., Ltd. Method for inhibiting tyrosinase activity in treatment of skin
EP1571925A1 (en) * 2002-12-20 2005-09-14 Unilever N.V. Blood glucose regulating composition
JP4680571B2 (ja) 2003-12-25 2011-05-11 カルピス株式会社 経口摂取用保湿剤
EP2124603B1 (en) * 2006-12-20 2014-11-19 DuPont Nutrition Biosciences ApS Milk protein hydrolyzates with reduced immunogenic potential

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02138991A (ja) 1988-11-19 1990-05-28 Morinaga Milk Ind Co Ltd 低分子量ペプチド組成物およびその製造方法
JPH0469315A (ja) 1990-07-09 1992-03-04 Morinaga Milk Ind Co Ltd チロシナーゼ活性阻害剤
JPH04112753A (ja) 1990-08-31 1992-04-14 Snow Brand Milk Prod Co Ltd 低アレルゲン化したホエータンパク加水分解物及びその製造法
JPH04187619A (ja) * 1990-11-22 1992-07-06 Nonogawa Shoji Kk メラニン生成抑制剤および化粧料
JPH05209000A (ja) * 1991-12-27 1993-08-20 Snow Brand Milk Prod Co Ltd 低アレルゲン化ペプチド組成物
JPH07252126A (ja) * 1994-03-11 1995-10-03 Momotani Jiyuntenkan:Kk 美白化粧料
JPH0898656A (ja) * 1994-09-30 1996-04-16 Snow Brand Milk Prod Co Ltd ホエータンパク質ペプチド組成物及びその製造法
JPH0930928A (ja) * 1995-07-24 1997-02-04 Nitsusen Kagaku Kk 特定成分からなる乳清（ラクトスキン）含有の皮膚化粧料
JPH10218755A (ja) * 1997-02-07 1998-08-18 Morinaga Milk Ind Co Ltd メラニン産生抑制剤

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* Cited by examiner, † Cited by third party
Title
GUADIX A. ET AL.: "Production of whey protein hydrolysates with reduced allergenicity in stable membrane reactor", JOURNAL OF FOOD ENGINEERING, vol. 72, no. 4, 2006, pages 398 - 405, XP005080364 *
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JOURNAL OF JAPANESE SOCIETY OF PEDIATRIC ALLERGY AND CLINICAL IMMUNOLOGY, vol. 1, no. 36, 1987

Cited By (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2380581B1 (en) 2008-12-24 2019-06-26 Megmilk Snow Brand Co., Ltd. Muscle-building agent
AU2009332369B2 (en) * 2008-12-24 2016-06-02 Megmilk Snow Brand Co., Ltd. Muscle-building agent
TWI483684B (zh) * 2008-12-24 2015-05-11 Megmilk Snow Brand Co Ltd 肌肉增強劑
WO2010073531A1 (ja) * 2008-12-24 2010-07-01 雪印乳業株式会社 筋肉増強剤
EP2380581A1 (en) * 2008-12-24 2011-10-26 Megmilk Snow Brand Co., Ltd. Muscle-building agent
CN102264379A (zh) * 2008-12-24 2011-11-30 雪印惠乳业株式会社 肌肉增强剂
EP2380581A4 (en) * 2008-12-24 2014-08-20 Megmilk Snow Brand Co Ltd MUSCULAR DEVELOPMENT AGENT
EP2420244A4 (en) * 2009-04-16 2013-08-07 Megmilk Snow Brand Co Ltd MEANS TO PROMOTE FATTY CHANGE
EP2420244A1 (en) * 2009-04-16 2012-02-22 Megmilk Snow Brand Co., Ltd. Lipid metabolism-improving agent
CN102395376A (zh) * 2009-04-16 2012-03-28 雪印惠乳业株式会社 脂质代谢改善剂
CN102573880B (zh) * 2009-10-13 2014-11-05 雪印惠乳业株式会社 脂肪累积抑制剂
CN102573880A (zh) * 2009-10-13 2012-07-11 雪印惠乳业株式会社 脂肪累积抑制剂
WO2011046101A1 (ja) 2009-10-13 2011-04-21 雪印乳業株式会社 脂肪蓄積抑制剤
AU2010307691B2 (en) * 2009-10-13 2016-06-30 Megmilk Snow Brand Co., Ltd. Fat accumulation suppressor
AU2010307691A1 (en) * 2009-10-13 2012-04-05 Megmilk Snow Brand Co., Ltd. Fat accumulation suppressor
US20120289461A1 (en) * 2010-02-12 2012-11-15 Megmilk Snow Brand Co., Ltd. Protein synthesis promoter
US20140018292A1 (en) * 2010-02-12 2014-01-16 Megmilk Snow Brand Co., Ltd. Method of increasing liver protein synthesis
JP2011160757A (ja) * 2010-02-12 2011-08-25 Snow Brand Milk Prod Co Ltd タンパク質合成促進剤
AU2011215208B2 (en) * 2010-02-12 2015-11-05 Megmilk Snow Brand Co., Ltd. Protein synthesis promoter
WO2011099548A1 (ja) 2010-02-12 2011-08-18 雪印乳業株式会社 タンパク質合成促進剤
AU2011221852A1 (en) * 2010-03-04 2012-09-06 Megmilk Snow Brand Co., Ltd. Agent for preventing muscular atrophy
WO2011108692A1 (ja) 2010-03-04 2011-09-09 雪印乳業株式会社 筋肉萎縮防止剤
AU2011221852B2 (en) * 2010-03-04 2016-06-30 Megmilk Snow Brand Co., Ltd. Agent for preventing muscular atrophy
US9255123B2 (en) 2011-03-10 2016-02-09 Megmilk Snow Brand Co., Ltd. Skin-beautifying agent
JP2012188384A (ja) * 2011-03-10 2012-10-04 Snow Brand Milk Products Co Ltd 美肌剤
WO2012121286A1 (ja) * 2011-03-10 2012-09-13 雪印メグミルク株式会社 美肌剤

Also Published As

Publication number Publication date
CA2680544A1 (en) 2008-09-18
US9173902B2 (en) 2015-11-03
JP5274814B2 (ja) 2013-08-28
US20100135941A1 (en) 2010-06-03
KR101555067B1 (ko) 2015-09-22
HK1137151A1 (en) 2010-07-23
CN101616657A (zh) 2009-12-30
AU2008225531B2 (en) 2013-06-20
CN101616657B (zh) 2012-08-29
EP2138159A4 (en) 2012-07-25
KR20090119980A (ko) 2009-11-23
EP2138159A1 (en) 2009-12-30
AU2008225531A1 (en) 2008-09-18
JP2008255090A (ja) 2008-10-23
NZ579687A (en) 2013-11-29
CA2680544C (en) 2015-06-30

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