WO2008088042A1 - 心血管系組織培養用基材 - Google Patents

心血管系組織培養用基材 Download PDF

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Publication number
WO2008088042A1
WO2008088042A1 PCT/JP2008/050609 JP2008050609W WO2008088042A1 WO 2008088042 A1 WO2008088042 A1 WO 2008088042A1 JP 2008050609 W JP2008050609 W JP 2008050609W WO 2008088042 A1 WO2008088042 A1 WO 2008088042A1
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WO
WIPO (PCT)
Prior art keywords
culture
substrate
cardiovascular tissue
foam
reinforcement material
Prior art date
Application number
PCT/JP2008/050609
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English (en)
French (fr)
Inventor
Toshiharu Shinoka
Goki Matsumura
Yoshito Ikada
Shojiro Matsuda
Yuki Sakamoto
Tsuguyoshi Taira
Original Assignee
Gunze Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gunze Limited filed Critical Gunze Limited
Priority to JP2008554091A priority Critical patent/JPWO2008088042A1/ja
Priority to EP08703459A priority patent/EP2103683B1/en
Priority to AT08703459T priority patent/ATE535265T1/de
Priority to CN200880001363.XA priority patent/CN101568637B/zh
Priority to US12/523,124 priority patent/US8372433B2/en
Publication of WO2008088042A1 publication Critical patent/WO2008088042A1/ja

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C12N2533/40—Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Vascular Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

本発明の心血管系組織培養用基材は、生体吸収性材料からなる発泡体を生体吸収性材料からなる補強材によって強化したチューブ状の心血管系組織培養用基材であって、前記発泡体は、ラクチド（Ｄ、Ｌ、ＤＬ体）の含有量が５０～５４モル％、ε－カプロラクトンの含有量が５０～４６モル％であるラクチド（Ｄ、Ｌ、ＤＬ体）－ε－カプロラクトン共重合体からなり、前記補強材が前記発泡体によって被覆されたものである。
PCT/JP2008/050609 2007-01-18 2008-01-18 心血管系組織培養用基材 WO2008088042A1 (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2008554091A JPWO2008088042A1 (ja) 2007-01-18 2008-01-18 心血管系組織培養用基材
EP08703459A EP2103683B1 (en) 2007-01-18 2008-01-18 Substrate for culture of cardiovascular tissue
AT08703459T ATE535265T1 (de) 2007-01-18 2008-01-18 Substrat zur kultivierung von kardiovaskulärem gewebe
CN200880001363.XA CN101568637B (zh) 2007-01-18 2008-01-18 心血管组织培养用基材
US12/523,124 US8372433B2 (en) 2007-01-18 2008-01-18 Substrate for culture of cardiovascular tissue

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007009469 2007-01-18
JP2007-009469 2007-01-18

Publications (1)

Publication Number Publication Date
WO2008088042A1 true WO2008088042A1 (ja) 2008-07-24

Family

ID=39636042

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/050609 WO2008088042A1 (ja) 2007-01-18 2008-01-18 心血管系組織培養用基材

Country Status (6)

Country Link
US (2) US20080176206A1 (ja)
EP (1) EP2103683B1 (ja)
JP (2) JPWO2008088042A1 (ja)
CN (1) CN101568637B (ja)
AT (1) ATE535265T1 (ja)
WO (1) WO2008088042A1 (ja)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010013717A1 (ja) * 2008-07-29 2010-02-04 グンゼ株式会社 血管再生基材
JP2011139898A (ja) * 2009-12-08 2011-07-21 Jms Co Ltd 多孔性部材、多孔化方法および前記多孔性部材の製造方法
JP2013543760A (ja) * 2010-11-09 2013-12-09 コーネル ユニヴァーシティー 器官再生方法
JP2017029300A (ja) * 2015-07-30 2017-02-09 グンゼ株式会社 人工血管の補強部材

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US6283956B1 (en) 1998-11-30 2001-09-04 David H. McDaniels Reduction, elimination, or stimulation of hair growth
US6887260B1 (en) 1998-11-30 2005-05-03 Light Bioscience, Llc Method and apparatus for acne treatment
US9192780B2 (en) * 1998-11-30 2015-11-24 L'oreal Low intensity light therapy for treatment of retinal, macular, and visual pathway disorders
US20060212025A1 (en) 1998-11-30 2006-09-21 Light Bioscience, Llc Method and apparatus for acne treatment
JP2006522660A (ja) * 2003-04-10 2006-10-05 ライト バイオサイエンス，エルエルシー 細胞増殖及び遺伝子発現を調節するためのフォトモジュレーション方法及び装置
ES2572976T3 (es) 2003-07-31 2016-06-03 Gentlewaves Llc Sistema y método para el tratamiento fotodinámico de la piel
EP2546332B1 (en) 2011-07-13 2016-06-29 Universität Leipzig Nanotube carrier substrate for primary tissue culture
CN105873622B (zh) * 2013-12-16 2019-12-31 卫材R&D管理有限公司 血管重建移植材料
CN115082065A (zh) 2013-12-19 2022-09-20 维萨国际服务协会 基于云的交易方法和系统
CN109852574B (zh) * 2017-11-30 2021-11-16 山西加乐医疗科技有限责任公司 一种细胞支架及其制备方法
WO2019152691A1 (en) * 2018-01-31 2019-08-08 The Secant Group, Llc Woven graft composite with varied density
JP7397646B2 (ja) * 2019-12-12 2023-12-13 グンゼ株式会社 自動縫合器用縫合補強材

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010013717A1 (ja) * 2008-07-29 2010-02-04 グンゼ株式会社 血管再生基材
EP2311506A1 (en) * 2008-07-29 2011-04-20 Gunze Limited Base material for revascularization
CN102112160A (zh) * 2008-07-29 2011-06-29 郡是株式会社 血管再生基材
JPWO2010013717A1 (ja) * 2008-07-29 2012-01-12 グンゼ株式会社 血管再生基材
US8496714B2 (en) 2008-07-29 2013-07-30 Gunze Limited Base material for revascularization
EP2311506A4 (en) * 2008-07-29 2014-01-29 Gunze Kk BASIC MATERIAL FOR REVASCULARIZATION
JP2011139898A (ja) * 2009-12-08 2011-07-21 Jms Co Ltd 多孔性部材、多孔化方法および前記多孔性部材の製造方法
JP2013543760A (ja) * 2010-11-09 2013-12-09 コーネル ユニヴァーシティー 器官再生方法
US10946066B2 (en) 2010-11-09 2021-03-16 Cornell University Methods for organ regeneration
JP2017029300A (ja) * 2015-07-30 2017-02-09 グンゼ株式会社 人工血管の補強部材

Also Published As

Publication number Publication date
US20080176206A1 (en) 2008-07-24
CN101568637A (zh) 2009-10-28
US20100055781A1 (en) 2010-03-04
JPWO2008088042A1 (ja) 2010-05-13
EP2103683B1 (en) 2011-11-30
EP2103683A1 (en) 2009-09-23
JP5986535B2 (ja) 2016-09-06
JP2013150909A (ja) 2013-08-08
ATE535265T1 (de) 2011-12-15
EP2103683A4 (en) 2010-01-20
US8372433B2 (en) 2013-02-12
CN101568637B (zh) 2013-02-06

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