WO2008084533A1 - メニエール病治療薬 - Google Patents

メニエール病治療薬 Download PDF

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Publication number
WO2008084533A1
WO2008084533A1 PCT/JP2007/050172 JP2007050172W WO2008084533A1 WO 2008084533 A1 WO2008084533 A1 WO 2008084533A1 JP 2007050172 W JP2007050172 W JP 2007050172W WO 2008084533 A1 WO2008084533 A1 WO 2008084533A1
Authority
WO
WIPO (PCT)
Prior art keywords
sugar
disease
meniere
therapeutic agent
sugar alcohol
Prior art date
Application number
PCT/JP2007/050172
Other languages
English (en)
French (fr)
Inventor
Setsuko Takeda
Original Assignee
Kowa Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Co., Ltd. filed Critical Kowa Co., Ltd.
Priority to CN2007800496823A priority Critical patent/CN101626771B/zh
Priority to PCT/JP2007/050172 priority patent/WO2008084533A1/ja
Priority to EP07706519A priority patent/EP2127658A4/en
Priority to US12/448,804 priority patent/US8445461B2/en
Priority to KR1020097015925A priority patent/KR101406231B1/ko
Publication of WO2008084533A1 publication Critical patent/WO2008084533A1/ja
Priority to HK10105173.6A priority patent/HK1139064A1/xx

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/717—Celluloses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/723—Xanthans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/729—Agar; Agarose; Agaropectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/731—Carrageenans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/732—Pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/734—Alginic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals

Abstract

　本発明は、糖または糖アルコール類を有効成分とし、糖または糖アルコール類に対し５～５０重量％の多糖類を含有する、糖または糖アルコール類由来の瀉下作用を解消することで、内リンパ水腫減荷効果を確実にし、さらに増強した効果を有するメニエール病処置剤を提供する。当該処置剤は、ゲル製剤、粉末剤、顆粒剤等の形態で提供され得る。
PCT/JP2007/050172 2007-01-10 2007-01-10 メニエール病治療薬 WO2008084533A1 (ja)

Priority Applications (6)

Application Number Priority Date Filing Date Title
CN2007800496823A CN101626771B (zh) 2007-01-10 2007-01-10 梅尼埃病治疗药
PCT/JP2007/050172 WO2008084533A1 (ja) 2007-01-10 2007-01-10 メニエール病治療薬
EP07706519A EP2127658A4 (en) 2007-01-10 2007-01-10 THERAPEUTIC AGENT AGAINST MORBUS MENIERE
US12/448,804 US8445461B2 (en) 2007-01-10 2007-01-10 Pharmaceutical composition for meniere's disease
KR1020097015925A KR101406231B1 (ko) 2007-01-10 2007-01-10 메니에르병 치료약
HK10105173.6A HK1139064A1 (en) 2007-01-10 2010-05-26 Therapeutic agent for meniere's disease

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2007/050172 WO2008084533A1 (ja) 2007-01-10 2007-01-10 メニエール病治療薬

Publications (1)

Publication Number Publication Date
WO2008084533A1 true WO2008084533A1 (ja) 2008-07-17

Family

ID=39608438

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2007/050172 WO2008084533A1 (ja) 2007-01-10 2007-01-10 メニエール病治療薬

Country Status (6)

Country Link
US (1) US8445461B2 (ja)
EP (1) EP2127658A4 (ja)
KR (1) KR101406231B1 (ja)
CN (1) CN101626771B (ja)
HK (1) HK1139064A1 (ja)
WO (1) WO2008084533A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009116490A1 (ja) * 2008-03-21 2009-09-24 Takeda Setsuko メニエール病治療薬

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105727045A (zh) * 2016-04-15 2016-07-06 宁波优美科新材料有限公司 一种用于治疗梅尼埃病的药物
FR3101546B1 (fr) * 2019-10-07 2023-11-10 Roquette Freres Masquage du goût de l’isosorbide

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04346937A (ja) * 1991-05-24 1992-12-02 Kibun Foods Inc 苦味低減方法
JPH11180803A (ja) 1997-12-19 1999-07-06 Sanyo Kako Kk 工業用殺菌・静菌安定化製剤とその製法
JPH11180863A (ja) * 1997-10-16 1999-07-06 Nikken Chem Co Ltd メニエ−ル病治療薬
JP2001226293A (ja) * 2000-02-17 2001-08-21 Kotaro Kanpo Seiyaku Kk 服用補助剤
WO2006001344A1 (ja) * 2004-06-24 2006-01-05 Sanwa Kagaku Kenkyusho Co., Ltd. イソソルビド含有ゼリー製剤
JP2007001964A (ja) * 2005-06-21 2007-01-11 Setsuko Takeda メニエール病治療薬

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ES2148305T3 (es) * 1993-11-16 2000-10-16 Novartis Ag Derivados de aminoacidos ciclicos que tienen actividad inhibidora de ace y nep.
JPH10507942A (ja) * 1994-10-28 1998-08-04 イノベイティブ テクノロジーズ リミテッド 脱水ヒドロゲル
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JP4105732B2 (ja) 2006-03-01 2008-06-25 節子 竹田 メニエール病治療薬
JP4167283B2 (ja) 2006-09-28 2008-10-15 節子 竹田 甘味料
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JP5356655B2 (ja) 2007-03-20 2013-12-04 パナソニック株式会社 集水ます蓋
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JPH11180803A (ja) 1997-12-19 1999-07-06 Sanyo Kako Kk 工業用殺菌・静菌安定化製剤とその製法
JP2001226293A (ja) * 2000-02-17 2001-08-21 Kotaro Kanpo Seiyaku Kk 服用補助剤
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See also references of EP2127658A4
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009116490A1 (ja) * 2008-03-21 2009-09-24 Takeda Setsuko メニエール病治療薬

Also Published As

Publication number Publication date
KR101406231B1 (ko) 2014-06-12
EP2127658A4 (en) 2011-04-27
CN101626771B (zh) 2012-11-14
US20100120712A1 (en) 2010-05-13
US8445461B2 (en) 2013-05-21
KR20100014346A (ko) 2010-02-10
EP2127658A1 (en) 2009-12-02
CN101626771A (zh) 2010-01-13
HK1139064A1 (en) 2010-09-10

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