WO2006082824A1 - Composition entero-soluble matricielle a liberation prolongee - Google Patents

Composition entero-soluble matricielle a liberation prolongee Download PDF

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Publication number
WO2006082824A1
WO2006082824A1 PCT/JP2006/301619 JP2006301619W WO2006082824A1 WO 2006082824 A1 WO2006082824 A1 WO 2006082824A1 JP 2006301619 W JP2006301619 W JP 2006301619W WO 2006082824 A1 WO2006082824 A1 WO 2006082824A1
Authority
WO
WIPO (PCT)
Prior art keywords
release composition
sustained release
matrix
lipid
substance
Prior art date
Application number
PCT/JP2006/301619
Other languages
English (en)
Japanese (ja)
Inventor
Genji Kawano
Isamu Seto
Original Assignee
Nrl Pharma, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nrl Pharma, Inc. filed Critical Nrl Pharma, Inc.
Priority to JP2007501580A priority Critical patent/JP4050784B2/ja
Publication of WO2006082824A1 publication Critical patent/WO2006082824A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

L'invention concerne une composition entéro-soluble matricielle à libération prolongée contenant une substance active d'un point de vue physiologique, un agent de gélification, un composés organique de base et un excipient. L'invention concerne également un procédé de production de ladite composition, et un produit alimentaire, un produit pharmaceutique, ou d'autres produits semblables, comprenant ladite composition. La composition se caractérise en ce que la substance active d'un point de vue physiologique est une protéine, un polypeptide, un peptide ou un microorganisme, la substance active d'un point de vue physiologique et l'agent de gélification se présentant tous deux sous forme de particules en poudre enrobées d'un enrobage lipidique. Chacun des composants décrits ci-dessus et d'autres composants auxiliaires comprend un ou plusieurs éléments sélectionnés dans le groupe formé d'un métal alcalin, d'un métal terreux alcalin, de manganèse, de cuivre, de fer, de zinc et de cobalt.
PCT/JP2006/301619 2005-02-03 2006-02-01 Composition entero-soluble matricielle a liberation prolongee WO2006082824A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2007501580A JP4050784B2 (ja) 2005-02-03 2006-02-01 マトリックス型腸溶性・徐放性組成物

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2005027145 2005-02-03
JP2005-027145 2005-02-03

Publications (1)

Publication Number Publication Date
WO2006082824A1 true WO2006082824A1 (fr) 2006-08-10

Family

ID=36777208

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2006/301619 WO2006082824A1 (fr) 2005-02-03 2006-02-01 Composition entero-soluble matricielle a liberation prolongee

Country Status (2)

Country Link
JP (1) JP4050784B2 (fr)
WO (1) WO2006082824A1 (fr)

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008007496A (ja) * 2005-12-28 2008-01-17 Zenyaku Kogyo Kk 攪拌型造粒機を用いた製剤の製造方法
WO2009148058A1 (fr) * 2008-06-02 2009-12-10 株式会社カネカ Procédé de production de microcapsules par utilisation de graisse solide
JP2012502061A (ja) * 2008-09-04 2012-01-26 ファーナム・カンパニーズ・インコーポレーテッド チュアブルな徐放性製剤
WO2013122942A1 (fr) * 2012-02-14 2013-08-22 Purina Animal Nutrition Llc Minéraux intempérisés et leurs procédés de fabrication et d'utilisation
CN103859531A (zh) * 2012-12-12 2014-06-18 内蒙古伊利实业集团股份有限公司 一种含有食用营养胶体颗粒的蛋白饮品及其制备方法
CN103897180A (zh) * 2012-12-24 2014-07-02 深圳先进技术研究院 重金属离子完全抗原的制备方法
JP2014122184A (ja) * 2012-12-21 2014-07-03 Nisshin Pharma Inc キトサン含有組成物及びキトサンコーティング組成物
JP2014526242A (ja) * 2011-09-09 2014-10-06 プロバイオティカル・ソシエタ・ペル・アチオニ 大腸菌の様々なバイオタイプおよびクロストリジウム菌の様々なバイオタイプの増殖を阻害／低減する乳酸菌および／またはビフィズス菌の株
WO2015025979A1 (fr) 2013-08-21 2015-02-26 株式会社Ｎｒｌファーマ Procédé de production de microparticules
JP2016510064A (ja) * 2013-03-07 2016-04-04 キャプシュゲル・ベルジウム・エヌ・ヴィ 硬カプセル製剤
WO2019177172A1 (fr) * 2018-03-16 2019-09-19 味の素株式会社 Additif alimentaire et aliment pour animaux
CN112533486A (zh) * 2018-03-16 2021-03-19 味之素株式会社 饲料用添加剂及饲料
US10982184B2 (en) 2011-05-09 2021-04-20 Probiotical S.P.A. Bacterial strains capable of metabolizing oxalates
US11110135B2 (en) 2011-05-09 2021-09-07 Probiotical S.P.A. Bacterial strains belonging to the genus Bifidobacterium for use in the treatment of hypercholesterolaemia
US11110136B2 (en) 2013-05-14 2021-09-07 Probiotical S.P.A. Composition comprising lactic acid bacteria for use in the preventive and/or curative treatment of recurrent cystitis
US11446340B2 (en) 2011-05-09 2022-09-20 Probiotical S.P.A. Probiotic bacterial strains and symbiotic composition containing the same intended for infant food

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014168253A1 (fr) 2013-04-09 2014-10-16 国立大学法人東京大学 Inhibiteur de la formation de pièges extracellulaires dans les leucocytes
KR102483471B1 (ko) * 2020-02-13 2023-01-06 주식회사 페라메드 사료 첨가제 및 그의 제조방법
CN112741272B (zh) * 2021-01-18 2023-02-28 黑龙江中医药大学 一种高含量纳豆激酶的纳豆冻干粉的发酵方法

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02142735A (ja) * 1988-11-24 1990-05-31 Nippon Oil & Fats Co Ltd 高安定性腸内有用細菌製剤及びその製造方法
JPH0585941A (ja) * 1991-09-27 1993-04-06 Kyowa Hakko Kogyo Co Ltd マトリツクス製剤
JPH0952847A (ja) * 1995-08-10 1997-02-25 Sando Yakuhin Kk 徐放性製剤
JP2001510786A (ja) * 1997-07-22 2001-08-07 フアーマシア・アンド・アツプジヨン・アー・ベー 脂質剤及びタンパク質を含む脂質粒子の医薬組成物の製造方法
JP2004352669A (ja) * 2003-05-29 2004-12-16 Snow Brand Milk Prod Co Ltd ラクトフェリン組成物
JP2005068094A (ja) * 2003-08-26 2005-03-17 Nof Corp 腸溶性製剤およびその製造方法
WO2005025609A1 (fr) * 2003-09-10 2005-03-24 Nrl Pharma, Inc. Composition d'un produit a la lactoferrine
WO2006016595A1 (fr) * 2004-08-10 2006-02-16 Nrl Pharma, Inc. Complexe de lactoférine et méthode pour le produire

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02142735A (ja) * 1988-11-24 1990-05-31 Nippon Oil & Fats Co Ltd 高安定性腸内有用細菌製剤及びその製造方法
JPH0585941A (ja) * 1991-09-27 1993-04-06 Kyowa Hakko Kogyo Co Ltd マトリツクス製剤
JPH0952847A (ja) * 1995-08-10 1997-02-25 Sando Yakuhin Kk 徐放性製剤
JP2001510786A (ja) * 1997-07-22 2001-08-07 フアーマシア・アンド・アツプジヨン・アー・ベー 脂質剤及びタンパク質を含む脂質粒子の医薬組成物の製造方法
JP2004352669A (ja) * 2003-05-29 2004-12-16 Snow Brand Milk Prod Co Ltd ラクトフェリン組成物
JP2005068094A (ja) * 2003-08-26 2005-03-17 Nof Corp 腸溶性製剤およびその製造方法
WO2005025609A1 (fr) * 2003-09-10 2005-03-24 Nrl Pharma, Inc. Composition d'un produit a la lactoferrine
WO2006016595A1 (fr) * 2004-08-10 2006-02-16 Nrl Pharma, Inc. Complexe de lactoférine et méthode pour le produire

Cited By (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008007496A (ja) * 2005-12-28 2008-01-17 Zenyaku Kogyo Kk 攪拌型造粒機を用いた製剤の製造方法
WO2009148058A1 (fr) * 2008-06-02 2009-12-10 株式会社カネカ Procédé de production de microcapsules par utilisation de graisse solide
JP5677086B2 (ja) * 2008-06-02 2015-02-25 株式会社カネカ 固体脂を使ったマイクロカプセルの製造方法
JP2012502061A (ja) * 2008-09-04 2012-01-26 ファーナム・カンパニーズ・インコーポレーテッド チュアブルな徐放性製剤
US10668012B2 (en) 2008-09-04 2020-06-02 Farnam Companies, Inc. Chewable sustained release formulations
US11110135B2 (en) 2011-05-09 2021-09-07 Probiotical S.P.A. Bacterial strains belonging to the genus Bifidobacterium for use in the treatment of hypercholesterolaemia
US11446340B2 (en) 2011-05-09 2022-09-20 Probiotical S.P.A. Probiotic bacterial strains and symbiotic composition containing the same intended for infant food
US10982184B2 (en) 2011-05-09 2021-04-20 Probiotical S.P.A. Bacterial strains capable of metabolizing oxalates
JP2014526242A (ja) * 2011-09-09 2014-10-06 プロバイオティカル・ソシエタ・ペル・アチオニ 大腸菌の様々なバイオタイプおよびクロストリジウム菌の様々なバイオタイプの増殖を阻害／低減する乳酸菌および／またはビフィズス菌の株
WO2013122942A1 (fr) * 2012-02-14 2013-08-22 Purina Animal Nutrition Llc Minéraux intempérisés et leurs procédés de fabrication et d'utilisation
US9504269B2 (en) 2012-02-14 2016-11-29 Purina Animal Nutrition Llc Weatherized minerals and methods of making and using same
US10856561B2 (en) 2012-02-14 2020-12-08 Purina Animal Nutrition Llc Weatherized minerals and methods of making and using same
US10709154B2 (en) 2012-02-14 2020-07-14 Purina Animal Nutrition Llc Weatherized minerals and methods of making and using same
CN103859531A (zh) * 2012-12-12 2014-06-18 内蒙古伊利实业集团股份有限公司 一种含有食用营养胶体颗粒的蛋白饮品及其制备方法
CN103859531B (zh) * 2012-12-12 2017-05-31 内蒙古乳业技术研究院有限责任公司 一种含有食用营养胶体颗粒的蛋白饮品及其制备方法
JP2014122184A (ja) * 2012-12-21 2014-07-03 Nisshin Pharma Inc キトサン含有組成物及びキトサンコーティング組成物
CN103897180A (zh) * 2012-12-24 2014-07-02 深圳先进技术研究院 重金属离子完全抗原的制备方法
JP2019023216A (ja) * 2013-03-07 2019-02-14 キャプシュゲル・ベルジウム・エヌ・ヴィ 硬カプセル製剤
US10172803B2 (en) 2013-03-07 2019-01-08 Capsugel Belgium Nv Hard capsule formulation
JP2016510064A (ja) * 2013-03-07 2016-04-04 キャプシュゲル・ベルジウム・エヌ・ヴィ 硬カプセル製剤
US11110136B2 (en) 2013-05-14 2021-09-07 Probiotical S.P.A. Composition comprising lactic acid bacteria for use in the preventive and/or curative treatment of recurrent cystitis
WO2015025979A1 (fr) 2013-08-21 2015-02-26 株式会社Ｎｒｌファーマ Procédé de production de microparticules
WO2019177172A1 (fr) * 2018-03-16 2019-09-19 味の素株式会社 Additif alimentaire et aliment pour animaux
CN111885922A (zh) * 2018-03-16 2020-11-03 味之素株式会社 饲料用添加剂及饲料
JPWO2019177172A1 (ja) * 2018-03-16 2021-03-18 味の素株式会社 飼料用添加剤及び飼料
CN112533486A (zh) * 2018-03-16 2021-03-19 味之素株式会社 饲料用添加剂及饲料
JP7382011B2 (ja) 2018-03-16 2023-11-16 味の素株式会社 飼料用添加剤及び飼料

Also Published As

Publication number Publication date
JP4050784B2 (ja) 2008-02-20
JPWO2006082824A1 (ja) 2008-06-26

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