WO2004067397A1 - Bouchon interne de contenant pour fluide medical - Google Patents

Bouchon interne de contenant pour fluide medical Download PDF

Info

Publication number
WO2004067397A1
WO2004067397A1 PCT/JP2004/000456 JP2004000456W WO2004067397A1 WO 2004067397 A1 WO2004067397 A1 WO 2004067397A1 JP 2004000456 W JP2004000456 W JP 2004000456W WO 2004067397 A1 WO2004067397 A1 WO 2004067397A1
Authority
WO
WIPO (PCT)
Prior art keywords
discharge nozzle
chemical solution
inner plug
container body
throttle
Prior art date
Application number
PCT/JP2004/000456
Other languages
English (en)
Japanese (ja)
Inventor
Satoru Kaneko
Yukiko Futatsuka
Original Assignee
Kowa Company, Ltd.
Shinko Chemical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Company, Ltd., Shinko Chemical Co., Ltd. filed Critical Kowa Company, Ltd.
Priority to CN200480003106.1A priority Critical patent/CN1745020B/zh
Publication of WO2004067397A1 publication Critical patent/WO2004067397A1/fr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D47/00—Closures with filling and discharging, or with discharging, devices
    • B65D47/04—Closures with discharging devices other than pumps
    • B65D47/06—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages
    • B65D47/12—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages having removable closures
    • B65D47/122—Threaded caps
    • B65D47/123—Threaded caps with internal parts
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D47/00—Closures with filling and discharging, or with discharging, devices
    • B65D47/04—Closures with discharging devices other than pumps
    • B65D47/32—Closures with discharging devices other than pumps with means for venting

Definitions

  • the present invention relates to, for example, an inner plug of a chemical solution container that can discharge a substantially constant amount of a chemical solution such as a mouthwash by a predetermined number of times of shaking operations.
  • drug solutions such as mouthwashes are used after diluting a specified amount of water.
  • the drug solution flows out to the metering cup through the push-up pipe in the container body. Only can be discharged outside.
  • the metering cup incorporated into the mouth of the chemical solution container has a complicated structure, not only tends to have an excessively large external size and manufacturing cost, but also has to have a flexible container body. There was a problem that had to be.
  • an object of the present invention is not limited to a flexible container body having a very simple structure, and an approximately constant amount of a chemical solution is discharged by a predetermined number of swinging operations. It is an object of the present invention to provide an inner plug of a chemical solution container which can reduce the manufacturing cost. Disclosure of the invention
  • One aspect of the present invention is an inner plug attached to an opening of a container body, an upward discharge nozzle for replacing a chemical solution with air and flowing out every time a swing operation is applied to the container body, and a base side of the discharge nozzle. And an axial line is provided on an inner surface of the narrowed portion.
  • FIG. 1 is a sectional view of a main part of a chemical solution container.
  • FIG. 2 is an exploded perspective view of the chemical solution container.
  • FIG. 3 (A) is a bottom view of the inner plug, (B) is a cross-sectional perspective view taken along line 3B-3B of (A), and (C) is an enlarged view of a main part of (A).
  • FIG. 4 is a perspective view of the use state of the drug solution container.
  • FIG. 5 (A) is a plan view of the throttle portion of the discharge nozzle, (B) is a cross-sectional side view of (A), (C) is a plan view of a comparative example in which no streak is provided in the throttle portion of the discharge nozzle, and (D) is a plan view. It is a side sectional view of (C).
  • Figures 6 (A) and (B) are graphs showing emission test data.
  • FIG. 7 is an explanatory diagram showing emission test data.
  • FIGS. 8A and 8B are views corresponding to FIG. 3C showing another embodiment.
  • FIG. 9 is an enlarged sectional view of a main part showing another embodiment.
  • the inner plug 10 of the chemical solution container is attached to the mouth 21 of the container body 20 and includes a coaxial discharge nozzle 11 and a throttle unit 12.
  • the container body 20 is formed in a slightly flat rectangular shape so that it can be easily gripped with one hand, and a mouth 21 with a male screw 21a is formed at an upper part.
  • An outward engagement ring 21 b is formed at the upper end of the mouth 21.
  • the inner plug 10 is integrally formed of, for example, low-density polyethylene.
  • This inner stopper 10 has a skirt 13 that fits the mouth 21, an inward engagement ring 14 that engages the engagement ring 2 lb, and the skirt 13 is inserted into the mouth 21.
  • the engagement ring 14 By engaging the engagement ring 14 resiliently with the engagement ring 21b, the engagement ring 14 can be attached to the upper end of the opening 21 by one action, and can be prevented from coming off due to the swinging operation. .
  • FIGS. 3 (A), (B) and (C) a discharge nozzle 11 with a throttle portion 12 projects upward from the center of the inner plug 10.
  • Figure 3 ( (A) is a bottom view of the inner plug 10
  • FIG. (B) is a sectional perspective view taken along the line 3 B-3 B in FIG. (A)
  • FIG. FIG. 2 is an enlarged view of a main part of FIG.
  • the throttle portion 12 is formed on the base side of the discharge nozzle 11 and has a polygonal star-shaped cross section whose diameter is sufficiently smaller than the inner diameter of the discharge nozzle 11.
  • the mountain-shaped streaks 12d, 12d... In the axial direction are formed uniformly over the entire circumference.
  • the upper end of the constricted portion 12 is continuous with the lower end of the discharge nozzle 11 via a ring-shaped step 12 c, and the lower portion of the constricted portion 12 is a radial rib 1 2 in the skirt 13.
  • a boss 12b having a, 12a, ... protrudes downward from the top surface of the inner plug 10.
  • the inner diameter of the tip of the discharge nozzle 11 is smoothly enlarged, and an edge 11a is formed at the forefront.
  • a reinforcing guard ring 15 concentric with the discharge nozzle 11 and protruding upward is provided.
  • the container body 20 is provided with a screw-type cap 30 (see FIGS. 1 and 2).
  • the cap 30 has a female screw 31 matching the male screw 21 a of the container body 30, a skirt 3 2 for pressing the inner plug 10, and a plug portion 3 for closing the tip of the discharge nozzle 11. 3 and the auxiliary ring 3 3a are formed downward on the top surface.
  • the cap 30 is attached to the mouth 21 of the container body 20 to prevent the inner plug 10 from coming off through the skat 32 and to prevent the inner plug 10 and the container main body 20 from coming off. Of the mouth 21 can be improved.
  • the stopper 33 is inserted into the tip of the discharge nozzle 11, and the tip of the discharge nozzle 11 is inserted into a ring-shaped groove between the stopper 33 and the auxiliary ring 33 a. By inserting, the discharge nozzle 11 can be sealed watertight.
  • the inner stopper 10 is obtained by grasping the container body 20 from which the cap 30 has been removed downward by hand (see FIG. 4), and repeatedly swinging the container body upward and downward (arrows in the figure). (A direction), a substantially constant amount of the chemical solution can be discharged to the external container Y every time the squirting operation is performed, via the throttle unit 12 and the discharge nozzle 11.
  • the discharge nozzle 11 replaces the chemical solution in the container body 20 with air every time the squirting operation is performed, and causes the chemical solution to flow out.
  • the throttle section 12 regulates the flow amount of the chemical solution at this time to a substantially constant amount. Because it can be.
  • the inner diameter of the discharge nozzle 1 1 is Based on the tension, the diameter is set to the maximum diameter that is closed by the chemical solution and does not allow the chemical solution to flow naturally even when the container body 20 is inverted.
  • FIGS. 5A and 5B are detailed views of the discharge nozzle 11 and the throttle unit 12 shown in FIGS. 1 to 3, and FIGS. This is a comparative example in which 12 d, 12 d... Are not provided.
  • the inner diameter a and the length b of the discharge nozzle 11 are 3.8 mm and 7.5 mm, respectively, and the length c of the constricted portion 12 is 2.9 mm. Further, the maximum diameter d l and the minimum diameter d 2 of the constricted portion 12 are 2.8 mm and 2.4 mm, respectively.
  • the inner diameter d of the narrowed portion 12 in FIGS. 5 (C) and 5 (D) is 2.8 mm.
  • Fig. 6 (A) shows the discharge characteristics of the chemical solution in the form of Figs. 5 (A) and (B), and Fig. 6 (B), and Figs.
  • the horizontal axis and vertical axis of (B) are the number of repetitions (times) and the discharge amount (mL) of the chemical solution for each of the three swing operations when the swing operation is repeated three times.
  • Fig. 7 shows the emission data in Figs. 6 (A) and (B) collectively as the average value of the number of repetitions of each of the three pulsing operations for every 10 (30 pulsing operations). Have been.
  • the discharge amount of the chemical solution for each of the three shake-out operations is approximately 1.2 mL, which is almost constant.
  • the container body 20 at this time is a molded container made of polyethylene terephthalate having an effective height of about 60 mm from the bottom to the middle of the shoulder forming the mouth 21. Therefore, when the number of repetitions exceeds about 40 times, the remaining amount of the chemical solution in the container body 20 decreases, and the discharge amount for each swing operation decreases.
  • the inner plug 10 can achieve good discharge characteristics regardless of the shape of the inner surface of the squeezed portion 12 by using a plastic material having a contact angle to a chemical solution of 80 ° or more with a wettability.
  • the streaks 12 d, 12 d... Formed on the inner surface of the constricted portion 12 may have their shapes and the number of strips changed as appropriate, and have different depths. Streaks 12d, 12d ... may be mixed appropriately (not shown).
  • the aperture The cross-sectional area of the nozzle 12 is preferably set to be 0.2 to 0.6 times that of the discharge nozzle 11.
  • the discharge nozzle 11 and the constricted portion 12 coaxially form a step 12 having an inclination angle 90 ° with respect to the common axis C between the discharge nozzle 11 and the inner surface of the discharge nozzle 11. c may be formed.
  • the throttle portion 12 may be formed at an intermediate position in a range where the inner diameter of the discharge nozzle 11 does not change, instead of the base side of the discharge nozzle 11.
  • the inner plug attached to the mouth of the container body is formed at the base of the discharge nozzle, with an upward discharge nozzle that replaces the chemical solution with air and flows out every time a swing operation is applied to the container body.
  • a narrowed portion is provided on the inner surface of the narrowed portion.
  • the discharge nozzle replaces the chemical solution in the container body with air and flows out to the outside every time a swing operation is applied to the container body, and the throttle formed in the discharge nozzle has a streak provided on the inner surface.
  • the contact area with the chemical solution increases through this process, so that the chemical solution flowing to the discharge nozzle is regulated to a substantially constant amount for each oscillation operation, and the chemical solution flowing to the discharge nozzle is divided to cut off the continuity. It is possible to prevent dripping and improve the drainage of chemicals.
  • the throttle unit and the discharge nozzle can discharge a substantially constant amount of the chemical solution to the outside each time the ejection operation is performed.
  • the discharge nozzle is set to have a maximum diameter at which the chemical solution in the container body does not spontaneously flow even when the container body is tilted or inverted, that is, an inner diameter of about 3.0 to 5.0 mm.
  • the swing motion applied to the container body is, for example, by waving the hand holding the container body downward and vertically changing the sudden downward movement of the container body to the upward movement, thereby relatively moving the chemical solution in the container body up and down.
  • the container body shall be moved up and down linearly or in an arc so that it is downward at the lower end of the swinging operation.
  • the lower part of the narrowed portion may be projected downward as a boss having radial ribs.
  • the lower part of the throttle By forming the lower part of the throttle as a downward boss with radial ribs, The chemical liquid flowing into the section is divided via the ribs, and it is possible to suppress a variation in the discharge amount of the chemical liquid for each swing operation.
  • the rib can reinforce the inner plug when sealing the tip of the discharge nozzle via the cap, prevent deformation of the inner plug, and reduce the amount of the chemical solution remaining in the boss.
  • the throttle section is formed to have a sectional area ratio of 0.2 to 0.6 with respect to the discharge nozzle, is formed coaxially with the discharge nozzle, and is inclined with respect to a common axis between the discharge nozzle and the inner surface of the discharge nozzle.
  • a step having an angle of 90 ° or less may be formed.
  • the cross-sectional area ratio of the throttle section By setting the cross-sectional area ratio of the throttle section to 0.2 to 0.6 with respect to the discharge nozzle, it is possible to more uniformly suppress the discharge amount of the chemical solution for each swing operation. If the cross-sectional area ratio is larger than 0.6, the chemical solution is not easily cut, and there is no point in providing a throttle. If the cross-sectional area ratio is smaller than 0.2, the discharge amount of the chemical solution at each swinging operation becomes too small, and the practicality is poor.
  • the throttle portion coaxially with the discharge nozzle, the relative positional relationship between the throttle portion and the discharge nozzle with respect to the vertical direction is kept constant regardless of the holding direction of the container body, and the discharge amount of the chemical solution for each swing operation is maintained. Fluctuations can be reduced.
  • the throttle portion forms a step having an inclination angle of 90 ° or less with respect to a common axis with the inner surface of the discharge nozzle, thereby making it possible to further improve the cut of the chemical solution.
  • the step is undercut with respect to the flow of the chemical liquid flowing out of the throttle section into the discharge nozzle in a columnar manner, and vortices along the outflow direction of the chemical liquid are generated on the entire circumference of the chemical liquid, so that the chemical liquid is continuous.
  • the tilt angle at this time refers to the tilt angle of the surface of the step with respect to the axis center on the side of the aperture.
  • the discharge nozzle may form the edge at the forefront by smoothly expanding the inner diameter of the tip.
  • the discharge nozzle can smoothly separate the chemical solution from the tip by smoothly expanding the inner diameter of the tip and forming an edge at the tip.
  • the inner plug may be integrally formed of a plastic material having a contact angle with a chemical solution of 80 ° or more.
  • a plastic material having a contact angle to a chemical solution of 80 ° or more is preferable.
  • Such a plastic material has little wettability to the chemical solution and cuts the chemical solution more favorably.
  • Good plasticity such as polypropylene, high-density polyethylene, low-density polyethylene, polycarbonate, and polymethylpentene (trade name: TPX manufactured by Mitsui Chemicals, Inc.) are preferred.
  • Industrial applicability such as polypropylene, high-density polyethylene, low-density polyethylene, polycarbonate, and polymethylpentene (trade name: TPX manufactured by Mitsui Chemicals, Inc.) are preferred.
  • the discharge nozzle replaces the chemical solution with air every time the ejecting operation is performed and flows out. Since the amount of outflow can be regulated to a substantially constant amount, the amount of chemical solution discharged for each swing operation can be suppressed to a practically constant level despite the extremely simple structure as a whole. As a result, a substantially constant amount of the chemical solution can be discharged, and the container body is not limited to a flexible one, so that manufacturing costs can be reduced.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Closures For Containers (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Seeds, Soups, And Other Foods (AREA)
  • Devices For Dispensing Beverages (AREA)

Abstract

La présente invention concerne un bouchon interne d'un contenant pour fluide médical, comportant une tuyère de formation d'un jet (11) et une partie d'étranglement (12) formée dans la tuyère de formation d'un jet (11), ladite tuyère de formation d'un jet (11) débitant le fluide médical remplacé par de l'air au cours de chaque opération de basculement et la partie d'étranglement (12) étant capable de réguler le débit du fluide médical généralement constant. Ainsi, bien que le bouchon interne soit formé de manière généralement simple, le débit du fluide médical au cours de chaque opération de basculement peut être ramené à une valeur pratiquement constante de sorte que le débit généralement constant du fluide médical puisse être obtenu en un nombre spécifié d'opérations de basculement, et un corps de contenant (20) qui n'est pas exclusivement un corps souple. Il est ainsi possible de réduire les coûts de production.
PCT/JP2004/000456 2003-01-31 2004-01-21 Bouchon interne de contenant pour fluide medical WO2004067397A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN200480003106.1A CN1745020B (zh) 2003-01-31 2004-01-21 药液容器的内栓

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003-023015 2003-01-31
JP2003023015A JP4397600B2 (ja) 2003-01-31 2003-01-31 薬液容器の中栓

Publications (1)

Publication Number Publication Date
WO2004067397A1 true WO2004067397A1 (fr) 2004-08-12

Family

ID=32820707

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2004/000456 WO2004067397A1 (fr) 2003-01-31 2004-01-21 Bouchon interne de contenant pour fluide medical

Country Status (6)

Country Link
JP (1) JP4397600B2 (fr)
KR (1) KR100710962B1 (fr)
CN (1) CN1745020B (fr)
MY (1) MY136776A (fr)
TW (1) TWI255789B (fr)
WO (1) WO2004067397A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11963906B2 (en) 2019-03-28 2024-04-23 TearClear Corp. Devices and methods for flow control of ophthalmic formulations

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR200459421Y1 (ko) 2009-12-09 2012-03-28 박성주 약물용기용 캡
JP5940267B2 (ja) * 2011-08-31 2016-06-29 株式会社吉野工業所 中栓付き容器
JP6730574B2 (ja) * 2016-05-27 2020-07-29 シロウマサイエンス株式会社 容器
CN208264912U (zh) * 2018-03-28 2018-12-21 深圳市通产丽星股份有限公司 一种点滴软管
US10932947B2 (en) * 2018-04-11 2021-03-02 Paul Enemark Micro drop adapter for dropper bottles

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53161957U (fr) * 1977-05-21 1978-12-19
JPS58102449U (ja) * 1981-12-28 1983-07-12 株式会社資生堂 液体振出し壜の口栓
US4812071A (en) * 1986-08-27 1989-03-14 Batra Pran Correction fluid pen
EP0956904A1 (fr) * 1998-05-14 1999-11-17 Lameplast S.R.L. Buse pour délivrer des gouttes de liquide

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53161957U (fr) * 1977-05-21 1978-12-19
JPS58102449U (ja) * 1981-12-28 1983-07-12 株式会社資生堂 液体振出し壜の口栓
US4812071A (en) * 1986-08-27 1989-03-14 Batra Pran Correction fluid pen
EP0956904A1 (fr) * 1998-05-14 1999-11-17 Lameplast S.R.L. Buse pour délivrer des gouttes de liquide

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11963906B2 (en) 2019-03-28 2024-04-23 TearClear Corp. Devices and methods for flow control of ophthalmic formulations

Also Published As

Publication number Publication date
CN1745020A (zh) 2006-03-08
TWI255789B (en) 2006-06-01
JP4397600B2 (ja) 2010-01-13
CN1745020B (zh) 2010-04-28
TW200505757A (en) 2005-02-16
KR100710962B1 (ko) 2007-04-24
MY136776A (en) 2008-11-28
KR20050102084A (ko) 2005-10-25
JP2004262467A (ja) 2004-09-24

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