WO2003085372A2 - Biosensor membranes composed of polymers containing heterocyclic nitrogens - Google Patents

Biosensor membranes composed of polymers containing heterocyclic nitrogens Download PDF

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Publication number
WO2003085372A2
WO2003085372A2 PCT/US2002/015707 US0215707W WO03085372A2 WO 2003085372 A2 WO2003085372 A2 WO 2003085372A2 US 0215707 W US0215707 W US 0215707W WO 03085372 A2 WO03085372 A2 WO 03085372A2
Authority
WO
WIPO (PCT)
Prior art keywords
membrane
polymer
electrochemical sensor
crosslinker
group
Prior art date
Application number
PCT/US2002/015707
Other languages
English (en)
French (fr)
Other versions
WO2003085372A3 (en
WO2003085372A8 (en
Inventor
Fei Mao
Hyun Cho
Original Assignee
Therasense, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Therasense, Inc. filed Critical Therasense, Inc.
Priority to CA2447871A priority Critical patent/CA2447871C/en
Priority to EP02806821A priority patent/EP1466156B1/en
Priority to DE60226497T priority patent/DE60226497D1/de
Priority to AU2002367855A priority patent/AU2002367855B2/en
Priority to JP2003582513A priority patent/JP4112499B2/ja
Publication of WO2003085372A2 publication Critical patent/WO2003085372A2/en
Publication of WO2003085372A3 publication Critical patent/WO2003085372A3/en
Publication of WO2003085372A8 publication Critical patent/WO2003085372A8/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
    • A61B5/14865Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14546Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1468Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1473Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • C12Q1/002Electrode membranes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • C12Q1/004Enzyme electrodes mediator-assisted
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • C12Q1/005Enzyme electrodes involving specific analytes or enzymes
    • C12Q1/006Enzyme electrodes involving specific analytes or enzymes for glucose
PCT/US2002/015707 2001-05-15 2002-05-15 Biosensor membranes composed of polymers containing heterocyclic nitrogens WO2003085372A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA2447871A CA2447871C (en) 2001-05-15 2002-05-15 Biosensor membranes composed of polymers containing heterocyclic nitrogens
EP02806821A EP1466156B1 (en) 2001-05-15 2002-05-15 Biosensor membranes composed of polymers containing heterocyclic nitrogens
DE60226497T DE60226497D1 (de) 2001-05-15 2002-05-15 Aus heterocyclische stickstoffatome enthaltenden polymeren zusammengesetzte biosensormembranen
AU2002367855A AU2002367855B2 (en) 2001-05-15 2002-05-15 Biosensor membranes composed of polymers containing heterocyclic nitrogens
JP2003582513A JP4112499B2 (ja) 2001-05-15 2002-05-15 複素環窒素を含む重合体からなるバイオセンサ・メンブラン

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US29121501P 2001-05-15 2001-05-15
US60/291,215 2001-05-15
US10/146,518 US6932894B2 (en) 2001-05-15 2002-05-14 Biosensor membranes composed of polymers containing heterocyclic nitrogens
US10/146,518 2002-05-14

Publications (3)

Publication Number Publication Date
WO2003085372A2 true WO2003085372A2 (en) 2003-10-16
WO2003085372A3 WO2003085372A3 (en) 2004-08-12
WO2003085372A8 WO2003085372A8 (en) 2004-10-21

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/015707 WO2003085372A2 (en) 2001-05-15 2002-05-15 Biosensor membranes composed of polymers containing heterocyclic nitrogens

Country Status (10)

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US (13) US6932894B2 (US20030042137A1-20030306-C00007.png)
EP (3) EP1466156B1 (US20030042137A1-20030306-C00007.png)
JP (1) JP4112499B2 (US20030042137A1-20030306-C00007.png)
CN (1) CN1639206A (US20030042137A1-20030306-C00007.png)
AT (2) ATE394433T1 (US20030042137A1-20030306-C00007.png)
AU (1) AU2002367855B2 (US20030042137A1-20030306-C00007.png)
CA (2) CA2447871C (US20030042137A1-20030306-C00007.png)
DE (1) DE60226497D1 (US20030042137A1-20030306-C00007.png)
ES (1) ES2377331T3 (US20030042137A1-20030306-C00007.png)
WO (1) WO2003085372A2 (US20030042137A1-20030306-C00007.png)

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