WO2003075868A1 - Medicament et produit de soin pour la peau a base de levain et leur procede de production - Google Patents

Medicament et produit de soin pour la peau a base de levain et leur procede de production Download PDF

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Publication number
WO2003075868A1
WO2003075868A1 PCT/EP2003/002342 EP0302342W WO03075868A1 WO 2003075868 A1 WO2003075868 A1 WO 2003075868A1 EP 0302342 W EP0302342 W EP 0302342W WO 03075868 A1 WO03075868 A1 WO 03075868A1
Authority
WO
WIPO (PCT)
Prior art keywords
product
medicinal
cereal
care
sourdough
Prior art date
Application number
PCT/EP2003/002342
Other languages
German (de)
English (en)
Inventor
Gabriele Wolf
Original Assignee
Woresan Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Woresan Gmbh filed Critical Woresan Gmbh
Priority to AU2003212315A priority Critical patent/AU2003212315A1/en
Publication of WO2003075868A1 publication Critical patent/WO2003075868A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9794—Liliopsida [monocotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/12—Preparations containing hair conditioners

Definitions

  • the invention relates to a method for producing a medicinal and care agent for the skin based on an acidified leaven, a medicinal and care product obtainable by this process, a cosmetic containing a medicinal and care product and the use of the medicinal and care product according to the invention in one Cosmetic.
  • DE 38 02 840 02 has already disclosed a process for producing a fermentation product containing lactic acid and viable lactic acid bacteria by acidifying an aqueous slurry of baked bread mass based on sourdough in lactic acid medium, the baked product of an acidified bread dough being used as the bread mass.
  • This fermentation product is said to be u. a. can be used as an aid in the treatment of the holistic organism of humans, animals and plants.
  • EP 0 530 861 B1 discloses a topical, antimicrobial pharmaceutical composition which comprises a mixture of C 6 to C 8 fatty acids.
  • DE 299 23 627 Ul relates to a medicinal and care agent for promoting blood circulation, for relieving muscle tension, for skin cleansing and for skin regeneration, which is applied to parts of the body or used as an additive to a water bath.
  • the product is characterized in that it is formed from a fermentation product of an acidified leaven '.
  • CH-A5-623 207 relates to a process for the production of foods containing a product from cereal germs fermented by lactic acid bacteria. There are no indications of any other use of the product outside of the food sector.
  • DE-A-39 05 055 discloses a whole grain product and a method for its production. The production of baked products or dry products based on a starting product is described, which is inoculated with a Lactobacillus culture after briefly germinating a grain.
  • WO-A-96/13981 discloses dry baked products and processes for their manufacture.
  • GB-A-1 539 756 relates to a process for the production of food products using cereal germ products fermented with lactic acid bacteria.
  • the object of the present invention was to improve the positive influences, in particular the effects known from DE 299 23 627 Ul.
  • the range of valuable ingredients of the well-known fermentation products is to be expanded, e.g. B. the amount of vitamins and other biotic factors can be increased.
  • fermentation products from germinated cereal products with heterofermentative lactic acid bacteria are suitable for solving the task at hand.
  • Natural products formed by fermentation that are brought into contact with the skin have the potential to positively influence skin that requires care.
  • the present invention relates to a method for producing a healing and care agent for the skin from fermentation products based on an acidified leaven, wherein 1.1 a germinated cereal product water and a bacteriological inoculum from the group of heterofermentative lactic acid bacteria, preferably LactobaciUus DSM 6037 and LactobaciUus DSM 6129, are added 1.2 and the approach until the metabolic activity of the
  • Microorganisms is acidified.
  • the germinated grain product is obtained, for example, by washing germinable seeds, preferably from organic cultivation, swelling and bringing them to sowing. Germination preferably takes place in packaged cultures.
  • the germinated sprouts are harvested after 36 to 48 hours. After the harvest, washing is done with cold, preferably ice-cold water.
  • the germinated sprouts can then be processed immediately or stored at temperatures up to 7 ° C for a long time. The storage time should not exceed 1 week.
  • the fermentation product is subjected to a stabilizing heating process near the boiling point.
  • the invention relates to a healing and care agent for the skin based on an acidified leaven obtainable by the process according to the invention.
  • the medicinal and care agent according to the invention advantageously has a high proportion of lactic acid obtained by fermentation of> 60% by weight (as a proportion of the total amount of acid).
  • the medicinal and care products according to the invention can be mixed with auxiliaries and carriers customary in cosmetics in order to produce cosmetics.
  • the medicinal and care products according to the invention which can be used are used in particular in the form of powders, cereal fluids, cereal serums and cereal gels.
  • the cosmetic according to the invention which can be produced from the medicinal and care products according to the invention can be used in particular in the form of ointments, powders, creams, lotions, gels, shampoos, hair rinses, packs, lipsticks, face and body masks, or combinations thereof.
  • a facial mask for cleaning can be produced from incidents known in cosmetic formulations, such as steareth-12 or steareth-21, glyceryl stearates, stearic acid, alkylbenzoates with chain lengths of in particular 12 to 15 carbon atoms, cetearylisononanoate, stearylheptanuate, octyl stearate, fragrance or aroma substances such as Persea Gratissima Avocadol (CosmoCare), the cereal gel or cereal fluid according to the invention, propylene glycol, fillers such as kaolin and water.
  • Another form of application can consist predominantly of serum according to the invention with a high lactic acid content as well as vitamins and other supplements.
  • a shampoo can typically contain increments, such as sodium laureth sulfate, disodium laureth sulfosuccinate, cocoamidopropyl betaine, PEG-7 glyceryl cocoate, the cereal serum according to the invention, fillers such as styrene-acrylate copolymers / Laureth-23, citric acid, polyquaternium-18 (Amer-Glychol) (Amereatol) -cocoate as well as water, preservatives and fragrances.
  • increments such as sodium laureth sulfate, disodium laureth sulfosuccinate, cocoamidopropyl betaine, PEG-7 glyceryl cocoate, the cereal serum according to the invention, fillers such as styrene-acrylate copolymers / Laureth-23, citric acid, polyquaternium-18 (Amer-Glychol) (Amereatol) -cocoate as well as water, preservatives
  • a typical spa pack can consist of cetearyl alcohol, ceteareth-12, ceteareth-20, PEG-75 lanolin, Triticum Vulgare (Dragoco), the cereal fluid or cereal serum according to the invention, hydroxycetyl or hedroxyethyl dimonium chlorite from Henkel, panthenol, citric acid as well as water, preservatives and fragrances.
  • a hair conditioner can in particular consist of the cereal fluid or cereal serum according to the invention with fragrances, preservatives and fillers, for example fruit vinegar, glycerol, cetearyl alcohol, ceteareth-12, cetrimonium chlorite, PEG-75 lanolin, preservatives, fragrances and water.
  • fragrances for example fruit vinegar, glycerol, cetearyl alcohol, ceteareth-12, cetrimonium chlorite, PEG-75 lanolin, preservatives, fragrances and water.
  • fragrances for example fruit vinegar, glycerol, cetearyl alcohol, ceteareth-12, cetrimonium chlorite, PEG-75 lanolin, preservatives, fragrances and water.
  • fragrances for example fruit vinegar, glycerol, cetearyl alcohol, ceteareth-12, cetrimonium chlorite, PEG-75 lanolin, preservatives, fragrances and water.
  • the medicinal and care agent according to the invention is used in the form of a cereal fluid. It is a creamy raw material obtained from cereal gel, which excels in creams, lotions, shampoos, hair conditioners and packs.
  • the cereal gel according to the invention is a rather viscous raw material that can also be used directly as a medicinal and care agent according to the invention. It is the product obtained more or less directly from the fermentation process, which can be used in an unchanged form as a natural face or body mask and as a bath additive.
  • An advantage of this embodiment is the absence of potentially incompatible constituents which are stressful to the organism. After application, improvements in the skin relief and slowing of the formation of skin imperfections become apparent.
  • the agent can serve as a biological peeling agent for dead skin flakes, with a moisturizing effect advantageously appearing.
  • a cereal serum can in turn be obtained from cereal fluid. It is suitable as a raw material for incorporation into face and body masks, lipsticks, shampoos and conditioners as well as hair packs.
  • grain powder for example, grain powder, grain fluid and grain serum can be produced.
  • the grain powder can be produced by separating the solids from the grain gel according to the invention, which is then dried and ground.
  • the solids of the cereal powder can be used as peeling bodies in the cosmetics according to the invention.
  • the cereal fluid is produced, for example, by separating it from the purified gel and enriching it with unfiltered grain serum until the viscosity suitable for the use has been set. This product is a raw material with a high proportion of active ingredients.
  • the cereal serum is produced, for example, by filtering the liquid supernatant of the cereal gel according to the invention obtained from the fermentation and then clarifying it. This creates a product with a very high proportion of active ingredients.
  • the invention also relates to the use of the medicinal and care agents according to the invention in a cosmetic according to the invention.
  • a preferred use of the medicinal and care agents according to the invention in liposomes should be mentioned.
  • the present invention also relates to liposomes with the medicinal and care products according to the invention.
  • Germination of the grain 10 kg of germinable grain, for example rye grain are washed with cold water and soaked in cold water for 4 hours to swell. The water is then removed. The grain treated in this way is filled into a container with a large base and spread out. The grain layer then has a layer thickness of about 2 to 3 cm. The container is then covered. The temperature during germination is approx. 20 ° C. Germination is improved if the container is well ventilated. After about 40 hours, the grain germs are removed and washed in ice-cold water. The grain germs can then be processed directly or the germs can be stored at a maximum of 7 ° C.
  • part of the grain germinated according to Example 1 is mixed with two parts of water. Fermentation media with LactobaciUus DSM 6037 and LactobaciUus DSM 6129 are added to this mixture. This mixture is fermented at temperatures of 30 to 34 C for 24 to 48 hours. The fermentation is finished when a constant pH value is reached. The from the initial fermentation The mixture obtained is made up with 87.5 parts, based on the total volume of the initial fermentation, with water. The fermentation time is 24 to 48 hours until a constant pH is reached at a typical temperature of 30 to 34 C. Thereafter there is a thermal treatment for 3 to 5 hours at a temperature of 92 to 100 C.
  • Preservatives such as sorbic acid
  • benzoic acid Typically, 0.75 part of sorbic acid can be used based on the total volume.
  • the preservation step is followed by the separation processes for the production of the individual fractions, such as grain serum and grain
  • the table shows a comparison of selected ingredients from the product according to the invention and a product that was not produced on the basis of germinated rye.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Birds (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne un procédé de production d'un médicament et d'un produit de soin pour la peau à base de levain entièrement levé. Selon ce procédé, de l'eau et un agent d'inoculation bactériologique issu du groupe des bactéries hétérofermentaires de l'acide lactique, de préférence le lactobacille DSM 6037 et le lactobacille DSM 6129, sont ajoutés à un produit céréalier germé. Puis la charge lève jusqu'à ce que les micro-organismes arrêtent leur activité métabolique.
PCT/EP2003/002342 2002-03-13 2003-03-07 Medicament et produit de soin pour la peau a base de levain et leur procede de production WO2003075868A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003212315A AU2003212315A1 (en) 2002-03-13 2003-03-07 Sourdough-based skin medication and skin care product, and production method

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02005692.5 2002-03-13
EP02005692 2002-03-13

Publications (1)

Publication Number Publication Date
WO2003075868A1 true WO2003075868A1 (fr) 2003-09-18

Family

ID=27798785

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2003/002342 WO2003075868A1 (fr) 2002-03-13 2003-03-07 Medicament et produit de soin pour la peau a base de levain et leur procede de production

Country Status (2)

Country Link
AU (1) AU2003212315A1 (fr)
WO (1) WO2003075868A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2301362A1 (fr) * 2009-09-28 2011-03-30 Woresan GmbH Mélange à base de levain
EP2572720A1 (fr) 2011-09-21 2013-03-27 Elzbieta Cosmetics B.V. Formulation et traitement pour l'acne

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1539756A (en) * 1976-06-03 1979-01-31 Japan Natural Food Co Ltd Process for preparing food products containing a lactic bacteria-fermented product of a cereal germ
CH623207A5 (en) * 1976-06-04 1981-05-29 Japan Natural Food Co Ltd Process for producing foodstuffs containing a cereal germ product fermented by lactic acid bacteria
DE3905055A1 (de) * 1989-02-18 1990-08-23 Eckes Fa Peter Getreidevollkornprodukte sowie verfahren zu ihrer herstellung
WO1996013981A1 (fr) * 1994-11-08 1996-05-17 Quest International B.V. Produits de boulangerie secs et leur procede de fabrication
EP0806144A2 (fr) * 1996-05-11 1997-11-12 Agrano Ag Production d'un améliorant biologique du pain, qui est fluide ou pâteux et utilisant les bactéries lactiques, et l'agent ainsi produit
DE29923627U1 (de) * 1999-03-23 2000-12-21 Isernhaeger Landkost Menge Gmb Heil- und Pflegemittel

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1539756A (en) * 1976-06-03 1979-01-31 Japan Natural Food Co Ltd Process for preparing food products containing a lactic bacteria-fermented product of a cereal germ
CH623207A5 (en) * 1976-06-04 1981-05-29 Japan Natural Food Co Ltd Process for producing foodstuffs containing a cereal germ product fermented by lactic acid bacteria
DE3905055A1 (de) * 1989-02-18 1990-08-23 Eckes Fa Peter Getreidevollkornprodukte sowie verfahren zu ihrer herstellung
WO1996013981A1 (fr) * 1994-11-08 1996-05-17 Quest International B.V. Produits de boulangerie secs et leur procede de fabrication
EP0806144A2 (fr) * 1996-05-11 1997-11-12 Agrano Ag Production d'un améliorant biologique du pain, qui est fluide ou pâteux et utilisant les bactéries lactiques, et l'agent ainsi produit
DE29923627U1 (de) * 1999-03-23 2000-12-21 Isernhaeger Landkost Menge Gmb Heil- und Pflegemittel

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2301362A1 (fr) * 2009-09-28 2011-03-30 Woresan GmbH Mélange à base de levain
WO2011036304A1 (fr) * 2009-09-28 2011-03-31 Woresan Gmbh Mélange à base de levain
CN102548419A (zh) * 2009-09-28 2012-07-04 沃森股份有限公司 基于酵母的混合物
JP2013505978A (ja) * 2009-09-28 2013-02-21 ヴォルザン ゲーエムベーハー パン種をベースとする混合物
US8729049B2 (en) 2009-09-28 2014-05-20 Woresan Gmbh Leaven-based mixture
EP2572720A1 (fr) 2011-09-21 2013-03-27 Elzbieta Cosmetics B.V. Formulation et traitement pour l'acne
WO2013041646A1 (fr) 2011-09-21 2013-03-28 Elzbieta Cosmetics Bv Formulation et traitement pour l'acné
US10765708B2 (en) 2011-09-21 2020-09-08 Jao Beheer Bv Formulation and treatment for acne

Also Published As

Publication number Publication date
AU2003212315A1 (en) 2003-09-22

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