WO2003015834A1 - Procede de desinfection - Google Patents
Procede de desinfection Download PDFInfo
- Publication number
- WO2003015834A1 WO2003015834A1 PCT/JP2002/008341 JP0208341W WO03015834A1 WO 2003015834 A1 WO2003015834 A1 WO 2003015834A1 JP 0208341 W JP0208341 W JP 0208341W WO 03015834 A1 WO03015834 A1 WO 03015834A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- light
- hydrogen peroxide
- disinfecting solution
- disinfecting
- disinfected
- Prior art date
Links
- 238000004659 sterilization and disinfection Methods 0.000 title claims abstract description 63
- 238000000034 method Methods 0.000 title claims abstract description 39
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims abstract description 137
- 230000000249 desinfective effect Effects 0.000 claims abstract description 91
- 239000012736 aqueous medium Substances 0.000 claims abstract description 7
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 claims description 18
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims description 17
- 230000001678 irradiating effect Effects 0.000 claims description 14
- 229910021645 metal ion Inorganic materials 0.000 claims description 14
- 230000003204 osmotic effect Effects 0.000 claims description 7
- 239000004094 surface-active agent Substances 0.000 claims description 6
- 230000002421 anti-septic effect Effects 0.000 abstract description 6
- 239000000243 solution Substances 0.000 description 64
- 239000000645 desinfectant Substances 0.000 description 43
- 230000000694 effects Effects 0.000 description 29
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 12
- 239000003755 preservative agent Substances 0.000 description 10
- 239000000126 substance Substances 0.000 description 10
- 241000894006 Bacteria Species 0.000 description 9
- 238000000354 decomposition reaction Methods 0.000 description 9
- 239000007788 liquid Substances 0.000 description 9
- 239000000523 sample Substances 0.000 description 9
- 230000001954 sterilising effect Effects 0.000 description 9
- 230000000844 anti-bacterial effect Effects 0.000 description 7
- XEEYBQQBJWHFJM-UHFFFAOYSA-N iron Substances [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 7
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 6
- 230000009931 harmful effect Effects 0.000 description 6
- -1 hydroxyl radicals Chemical class 0.000 description 6
- 244000005700 microbiome Species 0.000 description 6
- 238000006386 neutralization reaction Methods 0.000 description 6
- 230000002335 preservative effect Effects 0.000 description 6
- 230000002411 adverse Effects 0.000 description 5
- TUJKJAMUKRIRHC-UHFFFAOYSA-N hydroxyl Chemical compound [OH] TUJKJAMUKRIRHC-UHFFFAOYSA-N 0.000 description 5
- 239000007800 oxidant agent Substances 0.000 description 5
- 239000002504 physiological saline solution Substances 0.000 description 5
- 235000002639 sodium chloride Nutrition 0.000 description 5
- RGHNJXZEOKUKBD-SQOUGZDYSA-N D-gluconic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 description 4
- 239000002245 particle Substances 0.000 description 4
- 230000000704 physical effect Effects 0.000 description 4
- LMSDCGXQALIMLM-UHFFFAOYSA-N 2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetic acid;iron Chemical compound [Fe].OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O LMSDCGXQALIMLM-UHFFFAOYSA-N 0.000 description 3
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 3
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 239000000872 buffer Substances 0.000 description 3
- 229960003260 chlorhexidine Drugs 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 3
- 150000002500 ions Chemical class 0.000 description 3
- 229910052742 iron Inorganic materials 0.000 description 3
- 150000002978 peroxides Chemical class 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 230000009467 reduction Effects 0.000 description 3
- 239000011780 sodium chloride Substances 0.000 description 3
- 159000000000 sodium salts Chemical class 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- RGHNJXZEOKUKBD-UHFFFAOYSA-N D-gluconic acid Natural products OCC(O)C(O)C(O)C(O)C(O)=O RGHNJXZEOKUKBD-UHFFFAOYSA-N 0.000 description 2
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 2
- 239000003899 bactericide agent Substances 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
- 239000003054 catalyst Substances 0.000 description 2
- 239000002738 chelating agent Substances 0.000 description 2
- 239000000882 contact lens solution Substances 0.000 description 2
- 238000007796 conventional method Methods 0.000 description 2
- 230000002070 germicidal effect Effects 0.000 description 2
- 239000000174 gluconic acid Substances 0.000 description 2
- 235000012208 gluconic acid Nutrition 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- RBTARNINKXHZNM-UHFFFAOYSA-K iron trichloride Chemical compound Cl[Fe](Cl)Cl RBTARNINKXHZNM-UHFFFAOYSA-K 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000001590 oxidative effect Effects 0.000 description 2
- 230000001699 photocatalysis Effects 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 239000008213 purified water Substances 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- NDVLTYZPCACLMA-UHFFFAOYSA-N silver oxide Chemical compound [O-2].[Ag+].[Ag+] NDVLTYZPCACLMA-UHFFFAOYSA-N 0.000 description 2
- GEHJYWRUCIMESM-UHFFFAOYSA-L sodium sulfite Chemical compound [Na+].[Na+].[O-]S([O-])=O GEHJYWRUCIMESM-UHFFFAOYSA-L 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 239000002562 thickening agent Substances 0.000 description 2
- 239000012929 tonicity agent Substances 0.000 description 2
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 1
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 1
- KHOMMWHGIAOVKF-UHFFFAOYSA-N 2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetic acid;nickel Chemical compound [Ni].OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KHOMMWHGIAOVKF-UHFFFAOYSA-N 0.000 description 1
- BMUXBWLKTHLRQC-UHFFFAOYSA-N 2-azanylethanoic acid Chemical compound NCC(O)=O.NCC(O)=O.NCC(O)=O BMUXBWLKTHLRQC-UHFFFAOYSA-N 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- JPVYNHNXODAKFH-UHFFFAOYSA-N Cu2+ Chemical compound [Cu+2] JPVYNHNXODAKFH-UHFFFAOYSA-N 0.000 description 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- 229920000084 Gum arabic Polymers 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 1
- 229920001479 Hydroxyethyl methyl cellulose Polymers 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- IMQLKJBTEOYOSI-GPIVLXJGSA-N Inositol-hexakisphosphate Chemical compound OP(O)(=O)O[C@H]1[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O IMQLKJBTEOYOSI-GPIVLXJGSA-N 0.000 description 1
- 229910021578 Iron(III) chloride Inorganic materials 0.000 description 1
- SPAGIJMPHSUYSE-UHFFFAOYSA-N Magnesium peroxide Chemical compound [Mg+2].[O-][O-] SPAGIJMPHSUYSE-UHFFFAOYSA-N 0.000 description 1
- VEQPNABPJHWNSG-UHFFFAOYSA-N Nickel(2+) Chemical compound [Ni+2] VEQPNABPJHWNSG-UHFFFAOYSA-N 0.000 description 1
- RSPISYXLHRIGJD-UHFFFAOYSA-N OOOO Chemical compound OOOO RSPISYXLHRIGJD-UHFFFAOYSA-N 0.000 description 1
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 description 1
- 102000003992 Peroxidases Human genes 0.000 description 1
- IMQLKJBTEOYOSI-UHFFFAOYSA-N Phytic acid Natural products OP(O)(=O)OC1C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C1OP(O)(O)=O IMQLKJBTEOYOSI-UHFFFAOYSA-N 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 description 1
- LCTONWCANYUPML-UHFFFAOYSA-M Pyruvate Chemical compound CC(=O)C([O-])=O LCTONWCANYUPML-UHFFFAOYSA-M 0.000 description 1
- 241000978776 Senegalia senegal Species 0.000 description 1
- 241000607720 Serratia Species 0.000 description 1
- 241000607715 Serratia marcescens Species 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- 235000010489 acacia gum Nutrition 0.000 description 1
- 239000000205 acacia gum Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 208000030961 allergic reaction Diseases 0.000 description 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 239000002280 amphoteric surfactant Substances 0.000 description 1
- 239000003945 anionic surfactant Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 235000010323 ascorbic acid Nutrition 0.000 description 1
- 239000011668 ascorbic acid Substances 0.000 description 1
- 229960005070 ascorbic acid Drugs 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 229960000686 benzalkonium chloride Drugs 0.000 description 1
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 description 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 description 1
- 239000004327 boric acid Substances 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 239000003093 cationic surfactant Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- KXKPYJOVDUMHGS-OSRGNVMNSA-N chondroitin sulfate Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](OS(O)(=O)=O)[C@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O1 KXKPYJOVDUMHGS-OSRGNVMNSA-N 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 229910001431 copper ion Inorganic materials 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 239000012470 diluted sample Substances 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 230000001747 exhibiting effect Effects 0.000 description 1
- 231100000040 eye damage Toxicity 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 239000007951 isotonicity adjuster Substances 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 229960004995 magnesium peroxide Drugs 0.000 description 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 1
- 239000011976 maleic acid Substances 0.000 description 1
- 239000001630 malic acid Substances 0.000 description 1
- 235000011090 malic acid Nutrition 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229920000609 methyl cellulose Polymers 0.000 description 1
- 239000001923 methylcellulose Substances 0.000 description 1
- 235000010981 methylcellulose Nutrition 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 229910001453 nickel ion Inorganic materials 0.000 description 1
- 231100000989 no adverse effect Toxicity 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 108040007629 peroxidase activity proteins Proteins 0.000 description 1
- 235000002949 phytic acid Nutrition 0.000 description 1
- 239000000467 phytic acid Substances 0.000 description 1
- 229940068041 phytic acid Drugs 0.000 description 1
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 1
- 229920000191 poly(N-vinyl pyrrolidone) Polymers 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- 239000004584 polyacrylic acid Substances 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- 229910001923 silver oxide Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- PFUVRDFDKPNGAV-UHFFFAOYSA-N sodium peroxide Chemical compound [Na+].[Na+].[O-][O-] PFUVRDFDKPNGAV-UHFFFAOYSA-N 0.000 description 1
- 235000010265 sodium sulphite Nutrition 0.000 description 1
- AKHNMLFCWUSKQB-UHFFFAOYSA-L sodium thiosulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=S AKHNMLFCWUSKQB-UHFFFAOYSA-L 0.000 description 1
- 235000019345 sodium thiosulphate Nutrition 0.000 description 1
- 239000008399 tap water Substances 0.000 description 1
- 235000020679 tap water Nutrition 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 description 1
- 229940033663 thimerosal Drugs 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
- A61L2/186—Peroxide solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
- A61L12/02—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using physical phenomena, e.g. electricity, ultrasonics or ultrafiltration
- A61L12/06—Radiation, e.g. ultraviolet or microwaves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
- A61L12/02—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using physical phenomena, e.g. electricity, ultrasonics or ultrafiltration
- A61L12/06—Radiation, e.g. ultraviolet or microwaves
- A61L12/063—Ultraviolet radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
- A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
- A61L12/12—Non-macromolecular oxygen-containing compounds, e.g. hydrogen peroxide or ozone
- A61L12/124—Hydrogen peroxide; Peroxy compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/08—Radiation
- A61L2/10—Ultraviolet radiation
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/0005—Other compounding ingredients characterised by their effect
- C11D3/0078—Compositions for cleaning contact lenses, spectacles or lenses
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/39—Organic or inorganic per-compounds
- C11D3/3947—Liquid compositions
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
Definitions
- the present invention relates to a disinfecting method, and particularly, when disinfecting a medical device, especially a contact lens or an ophthalmic contact mirror, simply irradiates a disinfecting solution containing hydrogen peroxide with light of a predetermined wavelength.
- the present invention relates to a disinfection method having a feature that excellent disinfection effects can be realized and that the neutralization treatment of hydrogen peroxide after disinfection is no longer required. Background technology
- contact lenses have been classified into non-hydrous contact lenses and hydrous contact lenses, or into hard contact lenses and soft contact lenses. Therefore, when any of those contact lenses is used continuously, microorganisms such as bacteria attached to the surface of the lens may be removed while the lens is being removed from the eye and stored.
- contact lenses should be disinfected before wearing them, as they can proliferate, and these microorganisms can cause harmful effects such as infections on the eyes. It is necessary to perform disinfection before use, especially in the case of soft contact lenses because of the high risk of bacterial infection.
- a heat disinfection method using a boiling disinfectant and a chemical disinfection method using a disinfectant or an antiseptic have been mainly adopted.
- thermal disinfection method a boiling operation requiring a long time is required, and in recent years, the latter chemical disinfection method has been widely used.
- a contact lens solution containing a predetermined disinfectant / preservative is used, and the contact lens is immersed in the solution and subjected to a desired disinfection treatment.
- Hydrogen peroxide is also well known as a disinfectant / P-type preservative used in the chemical disinfection method.However, in order to obtain a desired disinfection effect, usually 3% (30,000 ppm) is used. ), And after disinfection, a neutralization treatment is required to decompose and detoxify the hydrogen peroxide remaining on the surface and inside of the contact lens. That is, even if a small amount of hydrogen peroxide remains, there is a risk of causing serious damage to the eyes. Therefore, it has been conventionally used to rinse with physiological saline or use a metal catalyst such as platinum black.
- the present invention has been made in view of such circumstances, and a solution to the problem is to provide a simple and disinfecting method capable of exhibiting an excellent disinfecting effect. Is to do.
- the present invention has been completed based on such findings, and the gist of the present invention is to provide a disinfecting method using a disinfecting solution containing hydrogen peroxide in an aqueous medium.
- the disinfecting solution is stored in a predetermined container so as to have a depth of 3 to 10 mm, and the article to be disinfected is immersed in the disinfecting solution, and then at least in a depth direction of the disinfecting solution.
- the disinfection method is characterized in that the article to be disinfected is disinfected by irradiating light having a wavelength of 280 to 3885 nm.
- hydrogen peroxide is used as a disinfectant
- the disinfectant containing the hydrogen peroxide is 3 to 10 mm. Since it is housed at a relatively shallow depth and irradiates light of a predetermined wavelength in the depth direction, it is contained and dissolved in such a disinfecting solution. Light is uniformly and well irradiated to the hydrogen oxide. As a result, the hydrogen peroxide that has been exposed to light is effectively decomposed, and the strong oxidizing action of the hydroxyl radical ( ⁇ OH) generated during the decomposition of the hydrogen peroxide causes the sterilization of harmful microorganisms and the like. It is possible to do.
- an excellent disinfection effect can be realized simply and simply by irradiating the disinfectant containing hydrogen peroxide with light of a predetermined wavelength.
- the disinfectant containing hydrogen peroxide with light of a predetermined wavelength.
- hydrogen peroxide which is harmful to living organisms, is effectively and forcibly decomposed in a short period of time.
- it also has the advantage that extremely good bactericidal efficacy can be obtained and the neutralization treatment of hydrogen peroxide after disinfection is not required.
- the light irradiation is performed by irradiating light having a wavelength of 280 to 3885 nm, a high disinfection effect is realized without adversely affecting the articles to be disinfected. You get.
- the light irradiation is such that the light intensity at the main wavelength is 0.3 to 1.0 O mW / cm 2 with respect to the disinfecting solution.
- the irradiation is preferably carried out by irradiating light, whereby the hydrogen peroxide contained in the disinfecting solution can be advantageously decomposed, thereby immersing in the disinfecting solution.
- the disinfection effect of the articles to be disinfected (disinfected articles) can be advantageously enhanced.
- a configuration in which the concentration of the hydrogen peroxide is 1 to 500 ppm can be suitably adopted.
- excellent bactericidal efficacy can be advantageously ensured even at a low concentration.
- the disinfecting solution contains water-dispersible titanium oxide, a metal ion, a metal-EDTA complex, and a surfactant, if necessary. It may be contained, so that a further function according to those components is added. Specifically, the dispersing effect of water-dispersible titanium oxide can be enhanced, the effect of promoting decomposition of hydrogen peroxide by metal ions or metal-EDTA complex, or the effect of washing with a surfactant can be imparted. .
- the disinfecting solution used in the disinfecting method according to the present invention preferably has an osmotic pressure of 250 to 35 Om Osm, thereby disinfecting contact lenses and the like. Adverse effects on the article can be advantageously prevented, and the safety of living bodies such as eyes is further enhanced.
- a medical device for example, a contact lens or an ophthalmic contact mirror
- contact lenses can be advantageously disinfected.
- the disinfecting method according to the present invention uses a disinfecting solution containing hydrogen peroxide in an aqueous medium such as purified water, and the article to be disinfected in such a disinfecting solution.
- an aqueous medium such as purified water
- the disinfecting solution is irradiated with light having a wavelength of 280 to 38 nm to obtain It is used to disinfect articles to be disinfected.
- the disinfectant containing such hydrogen peroxide is accommodated in a relatively shallow depth or thickness of 3 to 10 mm.
- the remarkable feature of the present invention resides in that light of a predetermined wavelength is irradiated in the depth direction or the thickness direction.
- the disinfectant used in the present invention contains and dissolves hydrogen peroxide, which has been conventionally used as a disinfectant, and the article to be disinfected is immersed in such a disinfectant. Later, from the point where the light irradiation of the predetermined wavelength is performed, the irradiation light hits the hydrogen peroxide in the disinfecting solution, whereby the hydrogen peroxide receiving the light is irradiated. Is effectively decomposed. Then, upon the decomposition of the hydrogen peroxide, a hydroxyl radical is generated, so that the concentration of the hydroxyl radical in the disinfecting solution is increased in a short time, and thus the strong oxidation of the hydroxyl radical is caused.
- the disinfection is performed so that light of a predetermined wavelength can be uniformly and sufficiently irradiated to the hydrogen peroxide contained in the disinfecting solution.
- the liquid is stored in a predetermined container so as to have a relatively shallow depth or thickness of 3 to 1 Omm, and light is irradiated at least in the depth direction or the thickness direction. You have to. If the depth (thickness) of the disinfectant is less than 3 mm, the required amount of disinfectant will be small, and the amount of hydrogen peroxide will be small enough to achieve a sufficient disinfecting effect. This is because, depending on the item to be disinfected, it cannot be completely immersed, and there may be a part that cannot be disinfected.
- the depth (thickness) of the disinfectant exceeds 10 mm, the hydrogen peroxide on the front side in the irradiation direction is exposed to light, but the peroxide on the front side in the irradiation direction is irradiated. This is because hydrogen is not sufficiently irradiated with light and an effective disinfection effect cannot be obtained.
- the predetermined container for storing the disinfecting solution to have a depth or thickness of 3 to 1 Omm is not particularly limited, and has a size capable of accommodating the articles to be disinfected.
- various containers can be appropriately used as long as they can be accommodated so as to have a depth or thickness of O mm and allow light to pass at least in the depth direction or the thickness direction.
- a container made of a light-transmitting material can be advantageously used so that light irradiation can be performed from a plurality of directions. Using such a container, light irradiation is performed from the depth direction, the thickness direction, and other directions. As a result, the light irradiation efficiency can be effectively increased, and the disinfection effect can be more advantageously achieved.
- the disinfecting solution used in the present invention contains hydrogen peroxide as an oxidizing agent as a disinfectant, and the content of the hydrogen peroxide in the disinfecting solution is as expected.
- the concentration of hydrogen peroxide can be extremely low, for example, 1/60 or less.
- the hydrogen peroxide concentration generally, a concentration of 1 to 500 ppm, preferably 3 to 350 ppm, and more preferably 5 to 50 ppm can be adopted. If such a remarkably low concentration of hydrogen peroxide is employed, most of the hydrogen peroxide contained in the disinfecting solution can be decomposed by light irradiation, and the amount of remaining hydrogen peroxide can be reduced. Since the amount of water is extremely low, the neutralization treatment of hydrogen peroxide after disinfection becomes unnecessary, and as a result, if the economy and the usability are improved, the advantages can be enjoyed.
- the concentration of hydrogen peroxide is less than I ppm in the above concentration range, the disinfecting effect cannot be sufficiently achieved.On the contrary, if the concentration of hydrogen peroxide is too high, Although sufficient antiseptic effect can be obtained, there is a risk that hydrogen peroxide that remains without being decomposed by light irradiation may be present, and disinfected articles with such hydrogen peroxide attached, for example, medical devices, etc. If used, there is a risk of causing harmful effects on the living body. Therefore, it is necessary to neutralize the hydrogen peroxide remaining in the disinfecting solution as before.
- the disinfecting solution containing hydrogen peroxide in an appropriate amount may contain water-dispersible titanium oxide in addition to such hydrogen peroxide. That is, when water-dispersible titanium oxide is further contained, titanium oxide
- the disinfecting effect based on the photocatalytic action of tan and the disinfecting effect of hydrogen peroxide combine to provide a remarkably superior disinfecting effect as compared to the case of using them alone, and the disinfecting effect on the articles to be disinfected is advantageous. It is possible to increase it.
- the titanium oxide also generates hydroxyl radicals when irradiated with light, so that the decomposition reaction of organic substances such as harmful microorganisms can be performed very efficiently.
- the titanium oxide having such water dispersibility is not particularly limited as long as it can be dispersed in an appropriate aqueous medium, and generally has an average particle diameter of 15 ⁇ m or less. Titanium oxide having an average particle diameter of preferably 10 nm or less will be advantageously employed.
- the particle size of the titanium oxide is too large, it is difficult to maintain good transparency of the disinfecting solution, and thus, when irradiating light as described above, the fine particles on the near side in the irradiation direction In this way, the light is blocked from traveling further, and there is a problem in that the light does not hit the front side in the irradiation direction, resulting in a problem that the disinfection effect is significantly reduced.
- the water-dispersible titanium oxide used as the disinfecting effect-improving component is difficult to be adsorbed by the article to be disinfected, so that adding it changes the physical properties and shape of the article to be disinfected. And the occurrence of problems that adversely affect the living body can be advantageously avoided.
- the disinfecting solution used in the present invention may be added with metal ions as necessary.
- the addition of the metal ion causes a Fenton reaction between the hydrogen peroxide and the metal ion, further promoting the decomposition of the hydrogen peroxide.
- the concentration of the hydroxyl radical in the disinfecting solution is further increased, and a more excellent bactericidal action can be exhibited.
- metal ions include iron ions, nickel ions, and copper ions, and are not particularly limited. Among these metal ions, the effect of iron ions is particularly high. By adopting this, the decomposition of hydrogen peroxide is further promoted, and as a result, the improvement of the sterilization performance can be realized.
- such metal ions In general, a content of about 1 to 10 ppm is to be adopted.
- the various metal ions described above may be added or contained in a disinfecting solution as a metal-EDTA complex such as a Fe-EDTA complex, a Ni-EDTA complex, or a Cu-EDTA complex.
- the decomposition of hydrogen peroxide is also promoted by the presence of a metal-EDTA complex, as in the case where metal ions are contained (especially, in the case of iron ions), so that sterilization performance can be improved.
- a concentration of about 10 to 300 ppm is advantageously employed.
- the disinfecting solution as described above may further contain a surfactant for the purpose of cleaning the articles to be disinfected, apart from the disinfection of microorganisms, and such a surfactant may be a conventional one. Therefore, any of known anionic surfactants, nonionic surfactants, amphoteric surfactants, and cationic surfactants, which are generally used for contact lens solutions and the like, can be advantageously employed.
- the addition of the disinfecting solution gives the disinfecting solution a cleaning effect such as a lipid removing effect.
- the disinfecting solution used in the present invention includes, in addition to the above-mentioned hydrogen peroxide, titanium oxide, metal ions, metal-EDTA complex, and surfactant, if necessary, in the preparation of a normal disinfecting solution.
- Various known additives used for example, a chelating agent, a buffer, a thickener, a P-septic, a bactericide, an oxidizing agent, and a tonicity agent may be contained in combination. No problem. In addition, all of these components are safe for living bodies and do not inhibit the effect of hydrogen peroxide as described above, and in a quantitative range that does not impair the effect, Each will be used.
- one of the chelating agents included in such a disinfecting solution as needed generally has an effect of preventing the deposition of metal ions such as calcium on the articles to be disinfected.
- examples of such a component include ethylenediaminetetraacetic acid, cunic acid, gluconic acid, tartaric acid, phytic acid, and salts thereof (for example, sodium salt).
- the buffer is disinfected
- Typical buffers include cunic acid, malic acid, lactic acid, Examples include amino acids such as ascorbic acid, maleic acid, gluconic acid, phosphoric acid, boric acid, and glycine diglycinic acid; acids such as tris (hydroxymethyl) amino methane; and salts thereof (eg, sodium salt). You can do it.
- a thickener used for adjusting the viscosity of the disinfecting solution polyvinyl alcohol, poly (N-vinylpyrrolidone), polyethylene glycol, polyacrylamide and its hydrolyzate, polyacrylic acid, hydroxyethyl cellulose And carboxymethylcellulose, methylhydroxyethylcellulose, methylhydroxypropylcellulose, methylcellulose, gelatin, sodium alginate, sodium chondroitin sulfate, xanthan gum, gum arabic, gum gum and the like.
- various conventionally known compounds having a preservative or bactericidal effect can be added as the preservative, bactericide and oxidizing agent.
- examples of the oxidizing agent include peroxides such as ozone water, sodium peroxide, magnesium peroxide, and silver oxide.
- peroxides such as ozone water, sodium peroxide, magnesium peroxide, and silver oxide.
- Such an oxidizing agent (peroxide) is further contained in the disinfecting solution. By doing so, an even better disinfection effect can be obtained.
- the disinfectant used in the present invention may be used with the disinfectant remaining on the surface of the article to be disinfected treated with the disinfectant.
- the osmotic pressure is desirably set to 250 to 35 OmOsm so that no adverse effect can be caused on the living body. Therefore, in order to adjust to such a desired osmotic pressure, various known isotonic agents such as sodium chloride and potassium chloride are further added and contained in appropriate amounts in the disinfecting solution. It is desirable to be confused. For example, when sodium salt is used as the tonicity agent, an amount of 0.7 to 1.2% by weight based on the total weight of the disinfecting solution, preferably 0.8 to 1.2% by weight. It will be used in a proportion of 1.1% by weight.
- the osmotic pressure of the disinfectant is almost equal to the osmotic pressure of tears, even if the contact lens with the disinfectant remaining on the surface is worn as it is, the disinfectant may enter the eye. Irritation to the wearer's eyes can be advantageously reduced.
- aqueous medium containing various components as described above examples include water itself such as tap water, purified water, and distilled water, as well as a solution mainly composed of water, for example, physiological saline. Needless to say, known aqueous liquids such as a preserving solution for contact lenses and a cleaning solution can also be used.
- the disinfecting solution having the above-described various components appropriately added and contained is used to make the disinfecting solution 3 to 10 mm deep or thick.
- the article to be disinfected (disinfected article) is stored in a predetermined container and immersed in the disinfecting solution, and at least in the depth direction or the thickness direction of the disinfecting solution.
- the disinfection processing of the article to be disinfected is performed.
- the light for irradiating the disinfecting solution in which the article to be disinfected is immersed is generally from 250 to 38 5 so that the decomposition reaction of hydrogen peroxide can be advantageously promoted.
- Ultraviolet light (UV light) having a wavelength of nm, preferably 280-385 nm, more preferably 320-380 nm, will be employed.
- the light is not particularly limited as long as it contains light having such a wavelength as a main wavelength. Examples of the light include natural light, UV light emitted from an appropriate exposure device or light irradiation device, and a light bulb or a fluorescent lamp. UV light etc. can be used.
- the disinfected articles immersed in the disinfecting solution may be adversely affected, for example, contact lenses may be deteriorated.
- hydrogen peroxide has low stability to light, so it can be decomposed by irradiating light with a wavelength longer than 385 nm.
- the above wavelength range light having a dominant wavelength in the range of 250-385 nm Is adopted.
- the light intensity at the main wavelength is 0.3 to 1.0 mW / cm 2 . If the light intensity is too low, hydrogen peroxide cannot be sufficiently decomposed and the intended disinfection effect cannot be sufficiently achieved, and conversely, the light intensity is too high. Although the disinfecting effect is obtained, the disinfected article immersed in the disinfecting solution has an adverse effect. This is because there is a risk of being triggered.
- the time for irradiating the disinfectant with the light as described above to disinfect the target disinfected article depends on the type of the disinfected article, the wavelength of the light to be employed, It is determined appropriately taking into account the strength and other factors.However, in order to obtain the intended disinfection effect sufficiently, irradiation time of 30 minutes or more is usually required. In order to improve the efficiency of disinfection work, it is usually 12 hours, preferably about 6 hours.
- the disinfectant containing hydrogen peroxide is simply irradiated with light of a predetermined wavelength for a predetermined time, without any difficulty in handling the disinfectant.
- the disinfected articles can be easily and effectively disinfected.
- the article to be disinfected which has been subjected to the disinfection treatment according to the present invention is usually taken out of the disinfecting solution and used, and at this time, the concentration of hydrogen peroxide is used as the disinfecting solution.
- the concentration of hydrogen peroxide is used as the disinfecting solution.
- the amount of hydrogen peroxide remaining in the disinfectant is extremely small. It is not necessary to carry out the summing treatment, and it can be used as it is or after rinsing with physiological saline or the like.
- the items to be disinfected which are to be subjected to the disinfection processing as described above are as described above.
- medical tools especially contact lenses and ophthalmic contact mirrors
- contact lenses can be extremely effectively disinfected.
- the types of such contact lenses are not limited at all.
- soft contact lenses and hard contact lenses that are classified into all types, such as low water content and high water content, are applicable. It is possible to obtain the material of the contact lens at the time of applying the present invention.
- the hydrogen peroxide (H 2 0 2), an average particle diameter of 5 nm particulate titanium oxide (T i0 2), Fe ions, at least one of the Fe- EDTA complex the following Table 1 Prepare using sterile physiological saline (NaCl aqueous solution) containing 0.9% by weight of sodium chloride prepared separately to obtain the indicated concentration. Samples were prepared. It was confirmed that the osmotic pressure of each of these disinfectant solutions was about 280 to 29 OmO sm. Fe ions were introduced into the disinfectant by dissolving iron (III) chloride, and Fe-EDTA complex was dissolved by dissolving EDTA Fe'Na. ; Tatsun: Cppm]
- each disinfectant solution sample was placed in a sterilized 9 cm inner diameter dish at the depth of the solution shown in Table 1 above, and then used as test bacteria.
- Serratia 'Marusedzusensu: a (Serratia marcescens ATCC 13880), was inoculated to about 1 0 6 cf uZni L.
- 311] 1111 light was irradiated from the upper surface of the petri dish to the depth direction of the liquid for 3 hours.
- the intensity of light actually irradiated on the liquid surface of the disinfectant sample in a wavelength range around 365 nm was measured, and the results were combined with Table 1 above. Indicated.
- the disinfecting solution one containing hydrogen peroxide in an aqueous medium is used, and the disinfecting solution is 3 to 1 Omm is stored in a relatively shallow depth of O mm, and light with a wavelength of 280-385 nm is irradiated in the depth direction.
- the disinfecting solution it is possible to irradiate the article to be disinfected by irradiating the dissolved hydrogen peroxide with light uniformly and effectively.
- Simply irradiating the disinfectant solution with light provides a simple and extremely effective disinfection effect, making it possible to disinfect articles to be disinfected.
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
Description
Claims
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/482,505 US20040234569A1 (en) | 2001-08-20 | 2002-08-19 | Disinfection method |
EP02762803A EP1426064A4 (en) | 2001-08-20 | 2002-08-19 | DISINFECTION PROCESS |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001-248659 | 2001-08-20 | ||
JP2001248659 | 2001-08-20 | ||
JP2002-236242 | 2002-08-14 | ||
JP2002236242A JP2003135572A (ja) | 2001-08-20 | 2002-08-14 | 消毒方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2003015834A1 true WO2003015834A1 (fr) | 2003-02-27 |
Family
ID=26620644
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2002/008341 WO2003015834A1 (fr) | 2001-08-20 | 2002-08-19 | Procede de desinfection |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1426064A4 (ja) |
JP (1) | JP2003135572A (ja) |
WO (1) | WO2003015834A1 (ja) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004037302A1 (ja) * | 2002-10-28 | 2004-05-06 | Menicon Co., Ltd. | 消毒方法 |
WO2020198091A1 (en) * | 2019-03-22 | 2020-10-01 | Zeteo Tech, Inc. | Microwave assisted methods and systems for surface decontamination |
US11938243B2 (en) | 2019-03-22 | 2024-03-26 | Zeteo Tech, Inc. | Mobile systems for microwave assisted surface decontamination and decontamination methods |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20140018773A (ko) * | 2011-01-22 | 2014-02-13 | 가부시키가이샤 에이제트 | 살균 방법 및 살균 장치 |
TWI421128B (zh) * | 2011-09-23 | 2014-01-01 | Univ Nat Kaohsiung 1St Univ Sc | 以乙烯二胺四乙酸-鐵錯合物加速光催化反應之方法 |
EP4031645A1 (en) * | 2019-09-20 | 2022-07-27 | Reair S.r.l. | Sanitization composition and method for sanitization- purification of surfaces and environments |
Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1980001457A1 (en) * | 1979-01-11 | 1980-07-24 | J Peel | Method of sterilisation |
JPS5675158A (en) * | 1979-11-27 | 1981-06-22 | Dainippon Printing Co Ltd | Sterilizer |
JPS56113530A (en) * | 1980-02-13 | 1981-09-07 | Dainippon Printing Co Ltd | Method of sterilizing packing material |
EP0045201A1 (en) * | 1980-07-29 | 1982-02-03 | Liquipak International B.V. | A method of rendering material aseptic |
JPS61142130A (ja) * | 1984-12-06 | 1986-06-30 | 凸版印刷株式会社 | プラスチツク容器等の殺菌方法 |
WO1991004060A1 (en) * | 1989-09-21 | 1991-04-04 | Tomei Sangyo Kabushiki Kaisha | Cleaning and disinfection of soft contact lens and treating solution for soft contact lens |
WO1996005869A1 (en) * | 1994-08-23 | 1996-02-29 | Novartis Ag | Process for sterilizing articles and providing sterile storage environments |
JPH1133537A (ja) * | 1997-07-18 | 1999-02-09 | Fuji Photo Film Co Ltd | 液体又は気体の浄化方法 |
WO1999008932A1 (en) * | 1997-08-15 | 1999-02-25 | Tetra Laval Holdings & Finance S.A. | Uv radiation and vapor-phase hydrogen peroxide sterilization of packaging |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1233447B (it) * | 1987-12-30 | 1992-04-01 | Interox Chimica Spa | Procedimento di sbianca e di sterilizzazione di articoli in sughero e articoli in sughero sbiancati mediante detto procedimento |
US5120499A (en) * | 1990-01-11 | 1992-06-09 | U. V. Black Box Corporation | Method and system for asepticizing contact lenses and storing device |
DE19628133A1 (de) * | 1996-07-12 | 1998-01-15 | Heraeus Noblelight Gmbh | Verfahren zum Desinfizieren und Reinigen von Kleinteilen und dafür geeignete Vorrichtung |
JP4481470B2 (ja) * | 1999-11-01 | 2010-06-16 | 株式会社メニコン | コンタクトレンズの消毒方法及びそのための消毒液 |
-
2002
- 2002-08-14 JP JP2002236242A patent/JP2003135572A/ja not_active Withdrawn
- 2002-08-19 EP EP02762803A patent/EP1426064A4/en not_active Withdrawn
- 2002-08-19 WO PCT/JP2002/008341 patent/WO2003015834A1/ja active Application Filing
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1980001457A1 (en) * | 1979-01-11 | 1980-07-24 | J Peel | Method of sterilisation |
JPS5675158A (en) * | 1979-11-27 | 1981-06-22 | Dainippon Printing Co Ltd | Sterilizer |
JPS56113530A (en) * | 1980-02-13 | 1981-09-07 | Dainippon Printing Co Ltd | Method of sterilizing packing material |
EP0045201A1 (en) * | 1980-07-29 | 1982-02-03 | Liquipak International B.V. | A method of rendering material aseptic |
JPS61142130A (ja) * | 1984-12-06 | 1986-06-30 | 凸版印刷株式会社 | プラスチツク容器等の殺菌方法 |
WO1991004060A1 (en) * | 1989-09-21 | 1991-04-04 | Tomei Sangyo Kabushiki Kaisha | Cleaning and disinfection of soft contact lens and treating solution for soft contact lens |
WO1996005869A1 (en) * | 1994-08-23 | 1996-02-29 | Novartis Ag | Process for sterilizing articles and providing sterile storage environments |
JPH1133537A (ja) * | 1997-07-18 | 1999-02-09 | Fuji Photo Film Co Ltd | 液体又は気体の浄化方法 |
WO1999008932A1 (en) * | 1997-08-15 | 1999-02-25 | Tetra Laval Holdings & Finance S.A. | Uv radiation and vapor-phase hydrogen peroxide sterilization of packaging |
Non-Patent Citations (1)
Title |
---|
See also references of EP1426064A4 * |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004037302A1 (ja) * | 2002-10-28 | 2004-05-06 | Menicon Co., Ltd. | 消毒方法 |
EP1557180A1 (en) * | 2002-10-28 | 2005-07-27 | Menicon Co., Ltd. | Disinfection method |
EP1557180A4 (en) * | 2002-10-28 | 2007-09-05 | Menicon Co Ltd | DISINFECTION METHOD |
WO2020198091A1 (en) * | 2019-03-22 | 2020-10-01 | Zeteo Tech, Inc. | Microwave assisted methods and systems for surface decontamination |
US11524087B2 (en) | 2019-03-22 | 2022-12-13 | Zeteo Tech, Inc. | Microwave assisted methods and systems for surface decontamination |
US11872322B2 (en) | 2019-03-22 | 2024-01-16 | Zeteo Tech, Inc. | Microwave assisted methods and systems for surface decontamination |
US11938243B2 (en) | 2019-03-22 | 2024-03-26 | Zeteo Tech, Inc. | Mobile systems for microwave assisted surface decontamination and decontamination methods |
Also Published As
Publication number | Publication date |
---|---|
EP1426064A4 (en) | 2004-12-15 |
JP2003135572A (ja) | 2003-05-13 |
EP1426064A1 (en) | 2004-06-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP4481470B2 (ja) | コンタクトレンズの消毒方法及びそのための消毒液 | |
US20040234569A1 (en) | Disinfection method | |
US11331404B2 (en) | Disinfection system of contact lens | |
JPH05502874A (ja) | 非酸化的眼科組成物とその保存並びに使用方法 | |
US4986963A (en) | Method of disinfecting contact lenses with peracetic acid | |
EP1416975B1 (en) | Disinfecting and cleansing system for contact lenses | |
JP2013511337A (ja) | コンタクトレンズの消毒のための過酸化水素溶液及びキット | |
JP4484468B2 (ja) | コンタクトレンズの消毒方法及びそのための消毒液 | |
JP4244129B2 (ja) | 消毒方法 | |
WO2003015834A1 (fr) | Procede de desinfection | |
JP2005211545A (ja) | コンタクトレンズの消毒方法及びコンタクトレンズ用消毒液 | |
EP0819968A1 (en) | Disinfecting/washing composition for contact lenses and method for disinfecting and washing contact lenses by using the same | |
JPH03275063A (ja) | 過酸化水素分解触媒およびそれを用いたコンタクトレンズの消毒方法 | |
JP2004361714A (ja) | コンタクトレンズの保存/消毒方法 | |
JP3610986B2 (ja) | コンタクトレンズ用洗浄消毒液およびそれを用いたコンタクトレンズの洗浄消毒方法 | |
JPH04242649A (ja) | 含水性カラーコンタクトレンズの消毒方法 | |
KR940006102B1 (ko) | 콘택트렌즈 보존액 | |
JPH04226666A (ja) | コンタクトレンズの消毒洗浄方法 | |
JPH0519218A (ja) | ソフトコンタクトレンズの処理方法 | |
JPH05161694A (ja) | コンタクトレンズの処理方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A1 Kind code of ref document: A1 Designated state(s): US |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FR GB GR IE IT LU MC NL PT SE SK TR Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LU MC NL PT SE SK TR |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
WWE | Wipo information: entry into national phase |
Ref document number: 10482505 Country of ref document: US |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2002762803 Country of ref document: EP |
|
WWP | Wipo information: published in national office |
Ref document number: 2002762803 Country of ref document: EP |