WO2002100484A1 - Emplatre pour la peau muni d'un dispositif emettant de la lumiere et des rayonnements et procede pour l'utiliser - Google Patents

Emplatre pour la peau muni d'un dispositif emettant de la lumiere et des rayonnements et procede pour l'utiliser Download PDF

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Publication number
WO2002100484A1
WO2002100484A1 PCT/EP2002/006126 EP0206126W WO02100484A1 WO 2002100484 A1 WO2002100484 A1 WO 2002100484A1 EP 0206126 W EP0206126 W EP 0206126W WO 02100484 A1 WO02100484 A1 WO 02100484A1
Authority
WO
WIPO (PCT)
Prior art keywords
light
radiation
source
wound
skin patch
Prior art date
Application number
PCT/EP2002/006126
Other languages
German (de)
English (en)
Inventor
Michael Lenke
Original Assignee
Novicur Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novicur Ag filed Critical Novicur Ag
Publication of WO2002100484A1 publication Critical patent/WO2002100484A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0619—Acupuncture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0635—Radiation therapy using light characterised by the body area to be irradiated
    • A61N2005/0643—Applicators, probes irradiating specific body areas in close proximity
    • A61N2005/0645—Applicators worn by the patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/065—Light sources therefor
    • A61N2005/0651—Diodes

Definitions

  • the present invention relates to a skin plaster with at least one adhesive surface adhering to the skin and optionally a sterile fleece, which at least partially covers a wound, according to the preamble of claim 1 and also according to the preamble of claim 3, and also to a light or radiation-emitting device therefor the preamble of claim 12, and s , a method for increasing human well-being, in particular for the irradiation of wounds, according to the preamble of claim 16.
  • a light acupuncture treatment device has become known from DE 295 19 433 . in which the light pulses generated by a laser diode are used instead of the punctures generated by means of acupuncture needles for an acupuncture treatment.
  • the present invention proposes for the first time a skin patch with at least one adhesive surface adhering to the skin and optionally a sterile fleece that at least partially covers a miracle, in which the skin patch has a passage opening that essentially allows access to the wound and that has a cover that is transparent to light and radiation is provided, which rests on the side of the skin patch facing away from the wound.
  • a light or radiation-emitting device should be arranged on or above the light- or radiation-permeable cover.
  • the injured person can hold the wound supplied with the skin plaster according to the invention, for example, under a suitable radiation source in order to generally apply radiation to the wound without removing the plaster covering the wound with the usual use of conventional skin plasters and without having to cover the wound again after irradiation with a new skin patch.
  • the person concerned is no longer exposed to any risk to the eyes from the emitted radiation, since the light or radiation emitting Device with respect to the radiation direction of the wound, so that there is no risk that the radiation could be directed towards the eyes of the person concerned or escape.
  • the above-mentioned object is achieved by the first proposed method according to the invention for increasing human well-being, in particular for irradiating wounds.
  • a preferably monochromatic radiation generated by a light or radiation-emitting device for example in the form of a light-emitting diode and / or soft laser, is applied to the skin tissue to be irradiated in the area of the wound through a skin plaster with a passage opening that essentially makes the wound accessible, which is provided with a light-permeable or radiation-permeable cover, which rests on the side of the skin plaster facing away from the wound, is supplied and released there, preferably diffusely distributed.
  • a wound such as a graze, a cut or a burn, or a surgical scar or the like, can be exposed to radiation that promotes the wound healing process without provoking the aforementioned dangers.
  • the radiation source such as a light-emitting diode and / or a soft laser
  • the radiation source can be placed or attached for a long time above or above the wound to be treated and remain there without the wound becoming contaminated or affected is pulled. Due to the permanent availability of the radiation source, it can advantageously emit its radiation into the skin tissue in the area of the wound as often and as long as necessary, it being possible for the radiation to be emitted in a regulated or program-controlled manner by the intensity , optimally adjust the duration and type of radiation to the respective wound type and the wound healing process required.
  • the skin plaster according to the invention has the further advantage that it can be removed from the skin and disposed of after use or after the affected wound has healed, whereas the radiation source or the light or radiation-emitting device is removed or removed beforehand and again can be used. This helps to significantly save costs in the healthcare system.
  • the skin plaster according to the invention, the light or radiation-emitting device according to the invention and the method according to the invention advantageously have different biological effects of the radiation or bio-photons emitted by the light-emitting diode or the soft laser.
  • Primary or direct effects are the so-called biochemical effects, such as the stimulation of the release of anabolic substances or the modification of the normal enzymatic reactions in the wound.
  • bioelectrical effects such as the normalization of the membrane potential, which blocks the transmission of pain and thus improves the well-being of the person concerned.
  • bioenergetic effects such as the stimulation of metabolism and physiology.
  • secondary or indirect effects also advantageously occur. These are, for example, the stimulation of the microcirculation and the circulation of the cellular metabolism. Both the primary or direct as well as the secondary or indirect effects have a mutually reinforcing effect and ultimately help to shorten a wound healing process, which usually lasts for days or even weeks, so that a patient can be released from treatment much earlier , or inpatient treatment lent can be omitted. This can significantly reduce the treatment costs.
  • analgesic effect e.g. local sedation of pain due to anti-inflammatory effects
  • activation of the broad, myelinated ad webs which advantageously blocks the narrow ones
  • the anti-inflammatory and anti-edematous effects can be used in an advantageous manner by the biophotons influencing the natural defense mechanisms of the cells by stimulating phagocytosis. This also applies to the biostimulatory effect, which leads to a stimulation of tissue metabolism. All these effects help to promote a wound healing process and in this way are advantageously developed with the skin plaster according to the invention, which was first proposed and has an integrated light or radiation source.
  • the type of wound and, consequently, the healing process are determined by various aspects. These are the force of the violence, the cause (mechanical, thermal or chemical), the size and shape of the damaging medium, the direction of the skin lines and the type of tissue that has been injured. In some cases, not only is there superficial cutaneous erosion, but tissue layers at greater depths have been affected. This may have created a cavity in the body and substance loss may have occurred.
  • the skin patch according to the invention with an integrated light or radiation-emitting source can be used here and can be of great value in order to reconstruct tissue. In general, if there is a wound in the tissue with low elasticity and gaping wound edges, then the wounds of the cut vessels, muscles, tendons and nerves retract.
  • the use of the skin plaster according to the invention with an integrated light or radiation-emitting source can restore the granulation tissue through the biocompatible radiation available therewith. This is necessary in order to reconstruct lost tissue. It also advantageously accelerates the re-epithelization of the wound.
  • wound healing is to unite two bleeding areas and restore the original structure as quickly as possible. This must be done as soon as possible to prevent an infection that could disrupt or even prevent the homeopathy process.
  • the skin plaster according to the invention and the light or radiation-emitting device according to the invention save valuable time and decisively accelerate the wound healing process.
  • the skin plaster according to the invention with the integrated light or radiation source is stuck over the wound and the radiation treatment is started.
  • a dose of 4 J / cm can initially be assumed here, which primarily causes an increase in the number of connective tissue cells and stimulates the formation of new capillaries.
  • the regeneration of the epithelium is improved, with the result that the wound is completely closed again after a few days or even hours.
  • a wound can cause loss of substance, which is accompanied by separation of the wound edges.
  • infection or necrosis can occur arise. In these cases, the formation of granulation tissue with capillaries, connective tissue cells and leukocytes is necessary for the recovery process.
  • the formation of the latter in particular is not always guaranteed, especially not in the elderly and in poor nutrition.
  • the skin plaster according to the invention with an integrated light or radiation source is advantageously helpful to the person concerned. Because especially the bio-compatible radiation with bio-photons helps to achieve good results. For example, the regeneration process in the tissue around the wound can be promoted in a relatively short time due to the permanent availability of the light or radiation source and the biocompatible radiation that is available at any time to the extent that reddish, completely coherent granulation tissue is formed. The anti-inflammatory effect of bio-photon radiation prevents inflammation.
  • the treatment of any wound in which substance loss has occurred can concentrate on the two main forms of application: First, granulation tissue must be stimulated by irradiating the deep-lying parts of the wound with a dose of 3 to 4 J / cm become. This is easily possible with the light or radiation source of the skin plaster according to the invention and can be done automatically by the skin plaster itself or can be carried out by the patient by calling up corresponding treatment programs. Thereafter, care must be taken to stimulate the wound edge with appropriate radiation.
  • the light or radiation-emitting device of the skin patch according to the invention also does this independently, but it can also be carried out easily and even by the person concerned by calling up the corresponding program steps.
  • the light or radiation-emitting device is a light or radiation source which is preferably designed as a biophoton source and is supplied with the necessary voltage by an energy source which is preferably in the form of a direct current source, the light - Or radiation source is connected to this energy source by means of a circuit and the energy supply for light or.
  • Radiation source is regulated. In this way, the duration of the loading Radiation are regulated.
  • the regulation can take place, for example, by means of correspondingly configured circuits, via preferably programmable electronics, via operating elements or the like which can be reached from the outside.
  • the energies supplied by the light-emitting diode to the tissue by means of the biophoto-nes can advantageously be matched to the respective requirement.
  • an excessive supply of energy is avoided and on the other hand it is impossible for a treatment to be ended before the injured tissue has been supplied with sufficient new energies for a complete wound healing process.
  • the light or radiation source, the energy source and any circuit or control system used to regulate the emission of light or radiation are arranged on a circuit board, so that the most compact and space-saving construction possible is achieved.
  • a film construction can be used here, so that the light or radiation source is just as flexible and conformable to any prevailing body contour as the skin patch.
  • the light or. Radiation source at least one light emitting diode and / or at least one soft laser.
  • a light source for generating the radiation is provided which is harmless to the human eye.
  • the disadvantages of the risk of injury to the eyes known from laser therapy treatment devices with hard lasers are excluded.
  • light-emitting diodes in particular offer the further advantage that, like lasers, they can also provide monochromatic light, but their light or radiation does not decay. absolutely parallel and is therefore gentler, so to speak. In other words, the radiation from light emitting diodes is more suitable when irradiating human tissue in order to promote a wound healing process and thus decisively increase human well-being.
  • the photons, preferably monochromatic, generated by LEDs are also recently called biophotons due to their good biological compatibility. These biophotons help to increase human well-being, in particular, for example, to decisively promote the healing process in gaping or open wounds or also sewn wounds.
  • the biophotons generated by the light-emitting diodes can supply the cells in the skin tissue in the area of a wound with the energy required for healing.
  • the light energy or radiation generated by a soft laser or a light-emitting diode stimulates the mitochondria contained in a cell and produces the cell fuel adenosine triphosphate (ATP) in the excited cell.
  • ATP adenosine triphosphate
  • the light source is formed by ultra-bright red and / or blue LEDs.
  • the light energy emitted in particular by ultra-bright LEDs is approximately from 1,000 ⁇ candela. Since, in particular with red LEDs with a light wavelength of 600 nm to 660 nm, preferably around 630 nm, the first positive effects in the healing process can already be seen from this relatively low light energy quantity of approximately 1000 ⁇ candela the ultra bright red LEDs are preferred for a rapid wound healing process.
  • the LEDs used in the skin plaster according to the invention can be used with light energies in the range from approximately 3,000 to 25,000 ⁇ candela.
  • the light emitted by red LEDs is said to have a particularly anti-inflammatory effect.
  • the light generated by blue LEDs has an antiseptic effect.
  • a combination of red and blue LEDs in the light source thus helps to combine anti-inflammatory and antiseptic effects and to reinforce each other. In this way, the wound healing process required to heal an existing wound can be optimally tailored to the type and type of wound.
  • the use of differently colored LEDs offers the advantage of a color-controlled treatment. The injured person or the user can call up the pre-programmed treatment or radiation programs and the control of the light or radiation source takes over all other tasks, i.e.
  • the control of the LEDs or the soft laser and their supply with energy so that the desired light and color pattern for the respective irradiation can be called up as continuous light or pulsed or in other variations for use.
  • Time-dependent radiation patterns can also be depicted. For example, during or after deep sleep phases, in which the human body achieves the greatest healing success on its own, the irradiation of the wound to be healed can be specifically activated in order to positively strengthen the self-healing powers and thus decisively accelerate the wound healing process.
  • the light- or radiation-emitting device is covered by a housing or by this sem includes.
  • the housing is flush with the translucent or translucent cover and / or the skin patch.
  • the skin plaster according to the invention can thus advantageously first be positioned on or above the wound in such a way that it remains visible through its passage opening.
  • the light- or radiation-emitting device can then be placed and aligned on the light- or radiation-permeable cover, which is made of a clear plastic, for example, so that its radiation hits the tissue to be treated exactly or penetrates into the corresponding skin layers. can.
  • the light- or radiation-emitting device can then be covered or covered by the housing and thus reliably protected against external influences.
  • the light- or radiation-emitting device with a housing and to place and fasten the unit formed in this way on the skin patch over the light- or radiation-permeable cover.
  • the light- or radiation-permeable cover is formed from a crystal-clear plastic. This simplifies manufacturing and helps to save manufacturing costs.
  • the light- or radiation-permeable cover is designed as a diffusing screen or as a Fresnel lens. This means that both a compact, flat design and one possible wide scatter of light or radiation can be achieved, so that larger or larger wounds can be treated without problems.
  • the light- or radiation-emitting device covered by the housing is releasably connected to the skin patch again.
  • skin patch and radiation source can be separated after use.
  • the skin patch can be disposed of appropriately and the light or radiation source or a light source or radiation source, for example, from a housing with it or therein and the associated energy supply and electronics can be reused. In this way, costs can be saved and the degree of utilization of the light or radiation device can be significantly increased.
  • Fig. 1 in a schematically simplified manner in a three-dimensional view the structure of an exemplary embodiment of a skin patch according to the invention to promote wound healing, and
  • Fig. 2 is a schematically simplified sectional view of the skin plaster shown schematically in Fig. 1 in the state glued to the skin with the radiation device located thereon.
  • 1 schematically shows an embodiment of a skin plaster according to the invention with an integrated light or radiation-emitting device, such as a biophoton radiation source.
  • photon source 1 uses a high-power LED or a soft laser with radiation in the wavelength range from 420 nm to 900 nm.
  • the light-emitting diode 1 is fed via a corresponding circuit from an energy source which is designed, for example, as a direct current source 2.
  • the duration and intensity of the energy supplied is regulated by control electronics 3.
  • the light or radiation-emitting device consisting of light-emitting diode 1, direct current source 2 and electronic control unit 3, for example in the form of a biophoton radiation unit, is arranged above the skin patch 4 according to the invention and covered or encased by a housing 5.
  • the electronic components are mounted on a circuit board 6, not shown in FIG. 1. This can be seen, for example, from FIG. 2, which shows a schematic sectional view of the skin patch shown in FIG. 1.
  • Fig. 2 it can also be seen that the skin patch 4 is glued to the skin tissue 7 in the state shown.
  • the biophotons 8 generated by the light-emitting diode 1 penetrate the skin tissue 7. Here they cross through the clear cover 9, with which the through opening 10 of the skin patch 4 is covered to protect the wound against the light source.
  • the through opening 10 can be round, oval, triangular, rectangular, polygonal or in any other desired shape. For example, it can be punched out of a commercially available skin patch or cut out using other suitable methods. It is also conceivable to use only a base layer provided with the adhesive surfaces, to dispense with a sterile fleece and to introduce the through-opening into the skin patch 4 thus formed without a fleece.
  • the side of the skin patch facing away from the wound is cover, for example by gluing it along the edges. Furthermore, the side of the skin patch facing away from the wound can be appropriately prepared for receiving or supporting the light or radiation-emitting device 11 and can be provided with suitable adhesives, for example.
  • a skin plaster is thus created for the first time, which can be glued onto the skin by means of at least one adhesive surface adhering to the skin and in which a through opening is provided which essentially leaves a wound accessible, the through opening including a light or radiation-permeable cover is provided, which is placed on the side of the skin plaster facing away from the wound, so that radiation can penetrate through it into the wound or into the injured skin tissue from the outside in order to promote a wound healing process there.
  • Any light or radiation emitting source can be used for this.
  • a light or radiation-emitting device is preferably arranged above the light- or radiation-permeable cover.
  • the present invention for the first time creates a method for increasing human well-being, in particular for irradiating wounds, in which preferably monochromatic radiation generated by at least one light-emitting diode and / or soft laser passes through the skin tissue to be irradiated in the area of the wound a skin plaster with a passage opening that essentially allows access to the wound, which is provided with a light-permeable or radiation-permeable cover, which rests on the side of the skin plaster facing away from the wound, is supplied and is preferably diffusely distributed and dispensed there.

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  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

L'invention concerne une nouveauté consistant en un emplâtre pour la peau (4) comportant au moins une surface adhésive adhérant à la peau et éventuellement un non-tissé stérile recouvrant au moins en partie une plaie. Ce nouvel emplâtre (4) présente une ouverture de passage (10) permettant d'accéder sensiblement à la plaie, qui est recouverte d'un revêtement (9) perméable à la lumière est aux rayonnements, placé sur la face de l'emplâtre pour la peau (4), opposée à la plaie. L'invention concerne en outre un dispositif (11) émettant de la lumière et des rayonnements, prévu notamment pour un emplâtre pour la peau de ce type (4), qui comprend une source lumineuse et de rayonnement (1), une source d'énergie (2) et un circuit reliant la source lumineuse et de rayonnement (1) avec la source d'énergie (2). Ces différents éléments constitutifs sont recouverts ou entourés au moins en partie d'un boîtier (5). La source de lumière et de rayonnement (1) se présente de préférence sous forme de source de biophotons et la source d'énergie (2), quant à elle, se présente de préférence sous forme de source de courant continu. L'invention concerne par ailleurs un procédé permettant d'améliorer le confort des patients à l'aide de l'emplâtre pour la peau (4) obtenu selon l'invention et du dispositif émetteur de lumière et de rayonnements (11) selon l'invention.
PCT/EP2002/006126 2001-06-13 2002-06-04 Emplatre pour la peau muni d'un dispositif emettant de la lumiere et des rayonnements et procede pour l'utiliser WO2002100484A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2001128629 DE10128629A1 (de) 2001-06-13 2001-06-13 Hautpflaster, Licht bzw. Strahlung emittierende Vorrichtung hierfür, sowie Verfahren zur Anhebung des menschlichen Wohlbefindens
DE10128629.5 2001-06-13

Publications (1)

Publication Number Publication Date
WO2002100484A1 true WO2002100484A1 (fr) 2002-12-19

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DE (1) DE10128629A1 (fr)
WO (1) WO2002100484A1 (fr)

Cited By (7)

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WO2007126577A2 (fr) * 2006-03-28 2007-11-08 Carestream Health, Inc. Dispositif phototherapeutique utilisant des guides de lumiere
WO2008017975A1 (fr) 2006-08-07 2008-02-14 Koninklijke Philips Electronics N.V. Système de plâtre et dispositif de rayonnement
EP2422844A1 (fr) 2010-08-24 2012-02-29 Polyphotonix Limited Dispositif de photothérapie portable
GB2514892A (en) * 2013-04-12 2014-12-10 Avatar Star Technology Corp Phototherapy device
US20140379050A1 (en) * 2013-06-19 2014-12-25 Gcsol Tech Co., Ltd. Light acupuncture module
WO2019036444A1 (fr) * 2017-08-14 2019-02-21 Veralase, LLC Dispositif de traitement laser portable miniature
DE102022003609A1 (de) 2021-09-30 2023-03-30 Mehmet Karaduman Zuverlässige Vorrichtung zur Beschleunigung der Abheilung von infolge von Keimen verursachten Hautentzündungen und Desinfektion von Wunden und der Mundhöhle

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DE10335231B4 (de) * 2003-08-01 2007-06-28 Lts Lohmann Therapie-Systeme Ag Verfahren zur Verbesserung der Durchlässigkeit der menschlichen Haut und Pflaster für die transdermale Zufuhr von Wirkstoffen
GB0324254D0 (en) * 2003-10-16 2003-11-19 Euphotonics Ltd Apparatus for illuminating a zone of mammalian skin
DE102004018340B4 (de) * 2004-04-15 2017-02-09 Klaus Teichert Positioniereinrichtung zur Anbringung einer Stimulationseinrichtung am Körper eines Organismus, Behandlungsvorrichtung zur äußeren Stimulation des Organismus, medizinisches Gerät und Verfahren zur Signalübertragung
EP1839705A1 (fr) * 2006-03-27 2007-10-03 Universidad de Alcala Emplâtre cutané de thérapie laser
AT505280B1 (de) 2007-06-11 2008-12-15 Univ Wien Tech Vorrichtung zum bestrahlen von gewebe mit licht
EP2445586A1 (fr) * 2009-06-24 2012-05-02 Koninklijke Philips Electronics N.V. Appareil thérapeutique et son utilisation pour le traitement du psoriasis
WO2012010861A1 (fr) * 2010-07-22 2012-01-26 Ambicare Health Limited Dispositif jetable pour soins de la peau
DE102012013036B4 (de) 2012-06-29 2015-04-02 Isabellenhütte Heusler Gmbh & Co. Kg Widerstand, insbesondere niederohmiger Strommesswiderstand, sowie Beschichtungsverfahren hierzu
EP2992929B1 (fr) 2014-09-03 2017-11-01 GMG Beratungs- und Beteiligungs Verwaltungs GmbH Appareil de traitement avec un dispositif de positionnement et un dispositif de stimulation

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Publication number Priority date Publication date Assignee Title
WO2007126577A2 (fr) * 2006-03-28 2007-11-08 Carestream Health, Inc. Dispositif phototherapeutique utilisant des guides de lumiere
WO2007126577A3 (fr) * 2006-03-28 2007-12-21 Carestream Health Inc Dispositif phototherapeutique utilisant des guides de lumiere
WO2008017975A1 (fr) 2006-08-07 2008-02-14 Koninklijke Philips Electronics N.V. Système de plâtre et dispositif de rayonnement
JP2010500076A (ja) * 2006-08-07 2010-01-07 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ プラスタ及び放射装置のシステム
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EP2422844A1 (fr) 2010-08-24 2012-02-29 Polyphotonix Limited Dispositif de photothérapie portable
WO2012025399A1 (fr) 2010-08-24 2012-03-01 Polyphotonix Limited Dispositif de photothérapie portable
GB2514892A (en) * 2013-04-12 2014-12-10 Avatar Star Technology Corp Phototherapy device
US20140379050A1 (en) * 2013-06-19 2014-12-25 Gcsol Tech Co., Ltd. Light acupuncture module
WO2019036444A1 (fr) * 2017-08-14 2019-02-21 Veralase, LLC Dispositif de traitement laser portable miniature
US10799713B2 (en) 2017-08-14 2020-10-13 Veralase, LLC Miniature wearable laser treatment device
DE102022003609A1 (de) 2021-09-30 2023-03-30 Mehmet Karaduman Zuverlässige Vorrichtung zur Beschleunigung der Abheilung von infolge von Keimen verursachten Hautentzündungen und Desinfektion von Wunden und der Mundhöhle

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