WO2002088062A1 - Procede de preparation de derives d'alcool - Google Patents

Procede de preparation de derives d'alcool Download PDF

Info

Publication number
WO2002088062A1
WO2002088062A1 PCT/JP2002/003985 JP0203985W WO02088062A1 WO 2002088062 A1 WO2002088062 A1 WO 2002088062A1 JP 0203985 W JP0203985 W JP 0203985W WO 02088062 A1 WO02088062 A1 WO 02088062A1
Authority
WO
WIPO (PCT)
Prior art keywords
compound
general formula
represented
formula
alkyl group
Prior art date
Application number
PCT/JP2002/003985
Other languages
English (en)
Japanese (ja)
Inventor
Manabu Sasyou
Toshihiko Naito
Original Assignee
Eisai Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co., Ltd. filed Critical Eisai Co., Ltd.
Priority to JP2002585366A priority Critical patent/JPWO2002088062A1/ja
Publication of WO2002088062A1 publication Critical patent/WO2002088062A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/22—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of halogens; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

L'invention porte sur un procédé de préparation de dérivés d'alcool à application industrielle, plus particulièrement un procédé de préparation de composés représentés par la formule générale (6), leurs sels ou leurs hydrates, caractérisé par l'halogénation d'un composé représenté par la formule générale (5) : dans laquelle R désigne un alkyle C1-6 ; et X2 désigne un halogéno.
PCT/JP2002/003985 2001-04-23 2002-04-22 Procede de preparation de derives d'alcool WO2002088062A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2002585366A JPWO2002088062A1 (ja) 2001-04-23 2002-04-22 アルコール誘導体の製造方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001124861 2001-04-23
JP2001-124861 2001-04-23

Publications (1)

Publication Number Publication Date
WO2002088062A1 true WO2002088062A1 (fr) 2002-11-07

Family

ID=18974172

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/003985 WO2002088062A1 (fr) 2001-04-23 2002-04-22 Procede de preparation de derives d'alcool

Country Status (2)

Country Link
JP (1) JPWO2002088062A1 (fr)
WO (1) WO2002088062A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008016079A1 (fr) * 2006-08-02 2008-02-07 Nippon Shinyaku Co., Ltd. Procédé pour introduire un groupe protecteur d'acide nucléique

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996039411A1 (fr) * 1995-06-05 1996-12-12 Eisai Co., Ltd. Liposaccharides substitues utiles dans le traitement et la prevention de l'endotoxemie
JPH11171855A (ja) * 1997-12-05 1999-06-29 Sumitomo Chem Co Ltd 光学活性Ｎ置換α−アミノ−γ−ハロゲノ酪酸エステルの製造方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996039411A1 (fr) * 1995-06-05 1996-12-12 Eisai Co., Ltd. Liposaccharides substitues utiles dans le traitement et la prevention de l'endotoxemie
US5935938A (en) * 1995-06-05 1999-08-10 Eisai Co., Ltd. Substituted liposaccharides useful in the treatment and prevention of endotoxemia
JPH11171855A (ja) * 1997-12-05 1999-06-29 Sumitomo Chem Co Ltd 光学活性Ｎ置換α−アミノ−γ−ハロゲノ酪酸エステルの製造方法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
KATRITZKY ALAN R. ET AL.: "Nucleophilic additions to N-propargylpyridinium and to 1,3-propenediylbis (pyridinium) salts", J. ORG. CHEM., vol. 50, no. 6, 1985, pages 847 - 852, XP002955610 *
POHMAKOTR MANAT ET AL.: "A new synthesis of alpha, beta-unsaturated gamma- and delta-lactones via intramolecular acylation of alpha-sulfinyl carbanion", TETRAHEDRON LETT., vol. 26, no. 18, 1985, pages 2253 - 2256, XP002955609 *
TAKANO SEIICHI ET AL.: "Enantiodivergent synthesis of both enantiomers of sulcatol and matsutake alcohol from (R)-epichlorohydrin", CHEM. LETT., no. 10, 1987, pages 2017 - 2020, XP002955611 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008016079A1 (fr) * 2006-08-02 2008-02-07 Nippon Shinyaku Co., Ltd. Procédé pour introduire un groupe protecteur d'acide nucléique
US8158774B2 (en) 2006-08-02 2012-04-17 Nippon Shinyaku Co., Ltd. Method for introducing a nucleic-acid protecting group
JP5168145B2 (ja) * 2006-08-02 2013-03-21 日本新薬株式会社 核酸保護基の導入方法
KR101405632B1 (ko) 2006-08-02 2014-06-10 니뽄 신야쿠 가부시키가이샤 핵산 보호기의 도입 방법

Also Published As

Publication number Publication date
JPWO2002088062A1 (ja) 2004-08-12

Similar Documents

Publication Publication Date Title
WO2009155386A1 (fr) Procédé pour préparer le promoteur d'apoptose abt-263
JP2015533852A (ja) 胆汁酸誘導体を調製するためのプロセス
JP2006188470A (ja) インドリン誘導体およびその製造方法
EP1948626B1 (fr) Procede pour la preparation de delmopinol et de derives de celui-ci
CN115490697A (zh) 一种手性氮杂螺[4,5]-癸胺的不对称合成方法
WO2002088062A1 (fr) Procede de preparation de derives d'alcool
JPS62192382A (ja) メルカプトピラゾロピリミジンの製法
US5463051A (en) Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
WO2002083636A1 (fr) Derive de pyrolidine et son procede d'obtention
EP1926709A1 (fr) Procédé de synthèse d'un composé chiral de type 3-hydroxypyrrolidine et de dérivés dudit composé de pureté optique élevée
WO2002088072A1 (fr) Procede de preparation de composes d'alkylene
GB2290790A (en) Asymmetric synthesis of 6-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes
JPH04169583A (ja) フェノチアジン誘導体およびその製造方法
JPS63270650A (ja) Ｐ−（トランス−４−アミノメチルシクロヘキシルカルボニル）フエニルプロピオン酸の製造方法
JPS5846515B2 (ja) インド−ル誘導体の製造方法
JPH0597735A (ja) 光学活性二級アルコ−ルの製造方法
JPS60120844A (ja) ９−カルバモイルフルオレン誘導体の製法
CN117263941A (zh) 一种egfr抑制剂的制备方法
JP2903805B2 (ja) 光学活性ベンジルグリシジルエーテルの製法
TW202334107A (zh) 茚并[1,2-b]噁庚因-4-亞基化合物及其製造方法
CN114181145A (zh) 一种依匹哌唑中间体的制备方法
JP4447742B2 (ja) ３−メルカプト−１−（１，３−チアゾリン−２−イル）アゼチジンの製造法
JPH03176463A (ja) ピロリジノール誘導体およびその製法
JPH08245526A (ja) 光学活性なアミン類、光学活性なイミン類およびそれらの製造法
JPH01319496A (ja) ウラシル誘導体

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TN TR TT TZ UA UG US UZ VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2002585366

Country of ref document: JP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase