WO2002044192A1 - Derives de glucopyranosyloxybenzylbenzene, compositions medicinales contenant ces derives et produits intermediaires obtenus lors de l'elaboration de ces compositions - Google Patents
Derives de glucopyranosyloxybenzylbenzene, compositions medicinales contenant ces derives et produits intermediaires obtenus lors de l'elaboration de ces compositions Download PDFInfo
- Publication number
- WO2002044192A1 WO2002044192A1 PCT/JP2001/010115 JP0110115W WO0244192A1 WO 2002044192 A1 WO2002044192 A1 WO 2002044192A1 JP 0110115 W JP0110115 W JP 0110115W WO 0244192 A1 WO0244192 A1 WO 0244192A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- optionally substituted
- substituted lower
- intermediates
- production
- same
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002429833A CA2429833A1 (en) | 2000-11-30 | 2001-11-20 | Glucopyranosyloxybenzylbenzene derivatives, medicinal compositions containing the same and intermediates in the production thereof |
AU2002223127A AU2002223127A1 (en) | 2000-11-30 | 2001-11-20 | Glucopyranosyloxybenzyl benzene derivatives, medicinal compositions containing the same and intermediates in the production thereof |
US10/432,905 US7053060B2 (en) | 2000-11-30 | 2001-11-20 | Glucopyranosyloxybenzylbenzene derivatives, medicinal compositions containing the same and intermediates in the production thereof |
EP01998555A EP1344780A4 (en) | 2000-11-30 | 2001-11-20 | GLUCOPYRANOSYLOXYBENZYLBENZOLE DERIVATIVES, MEDICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION |
JP2002546562A JP4212891B2 (ja) | 2000-11-30 | 2001-11-20 | グルコピラノシルオキシベンジルベンゼン誘導体、それを含有する医薬組成物およびその製造中間体 |
US10/978,413 US7129381B2 (en) | 2000-11-30 | 2004-11-02 | Glucopyranosyloxybenzylbenzene derivatives, medicinal compositions containing the same and intermediates in the production thereof |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000366192 | 2000-11-30 | ||
JP2000-366192 | 2000-11-30 | ||
JP2000-380482 | 2000-12-14 | ||
JP2000380482 | 2000-12-14 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10432905 A-371-Of-International | 2001-11-20 | ||
US10/978,413 Division US7129381B2 (en) | 2000-11-30 | 2004-11-02 | Glucopyranosyloxybenzylbenzene derivatives, medicinal compositions containing the same and intermediates in the production thereof |
Publications (1)
Publication Number | Publication Date |
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WO2002044192A1 true WO2002044192A1 (fr) | 2002-06-06 |
Family
ID=26605024
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2001/010115 WO2002044192A1 (fr) | 2000-11-30 | 2001-11-20 | Derives de glucopyranosyloxybenzylbenzene, compositions medicinales contenant ces derives et produits intermediaires obtenus lors de l'elaboration de ces compositions |
Country Status (9)
Country | Link |
---|---|
US (3) | US7053060B2 (ja) |
EP (1) | EP1344780A4 (ja) |
JP (1) | JP4212891B2 (ja) |
AR (1) | AR034280A1 (ja) |
AU (1) | AU2002223127A1 (ja) |
CA (1) | CA2429833A1 (ja) |
PE (1) | PE20020573A1 (ja) |
TW (1) | TWI290556B (ja) |
WO (1) | WO2002044192A1 (ja) |
Cited By (26)
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EP1367060A1 (en) * | 2001-02-14 | 2003-12-03 | Kissei Pharmaceutical Co., Ltd. | Glucopyranosyloxybenzylbenzene derivatives and medicinal use thereof |
WO2004050122A1 (ja) * | 2002-12-04 | 2004-06-17 | Kissei Pharmaceutical Co., Ltd. | 高血糖症に起因する疾患の予防又は治療剤 |
JP2004196788A (ja) * | 2002-12-04 | 2004-07-15 | Kissei Pharmaceut Co Ltd | ベンジルフェノール誘導体、それを含有する医薬組成物およびその医薬用途 |
WO2004099230A1 (en) * | 2003-05-12 | 2004-11-18 | Fujisawa Pharmaceutical Co., Ltd. | Monosaccharide compounds |
JP2006510643A (ja) * | 2002-12-12 | 2006-03-30 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 新しい芳香族フルオログリコシド誘導体、該化合物を含有する医薬品、およびその使用 |
JP2006510644A (ja) * | 2002-12-12 | 2006-03-30 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 新しい複素環フルオログリコシド誘導体、該化合物を含有する医薬品、およびその使用 |
JP2006232825A (ja) * | 2005-01-31 | 2006-09-07 | Tanabe Seiyaku Co Ltd | 医薬組成物 |
JP2007518682A (ja) * | 2003-08-01 | 2007-07-12 | 田辺製薬株式会社 | 新規化合物 |
WO2007128761A2 (de) | 2006-05-04 | 2007-11-15 | Boehringer Ingelheim International Gmbh | Verwendungen von dpp iv inhibitoren |
WO2007147478A1 (de) | 2006-06-23 | 2007-12-27 | Merck Patent Gmbh | 3 -amino- imidazo [1, 2-a] pyridinderivate als sglt inhibitoren |
WO2008016132A1 (en) | 2006-08-04 | 2008-02-07 | Daiichi Sankyo Company, Limited | Benzyl phenyl glucopyranoside derivative |
JPWO2005095429A1 (ja) * | 2004-03-31 | 2008-02-21 | キッセイ薬品工業株式会社 | フェノール誘導体、それを含有する医薬組成物及びその医薬用途 |
WO2008070692A2 (en) | 2006-12-06 | 2008-06-12 | Smithkline Beecham Corporation | Bicyclic compounds and use as antidiabetics |
DE102007008420A1 (de) | 2007-02-21 | 2008-08-28 | Merck Patent Gmbh | Benzimidazolderivate |
DE102007048716A1 (de) | 2007-10-11 | 2009-04-23 | Merck Patent Gmbh | Imidazo[1,2-a]pyrimidinderivate |
WO2009096503A1 (ja) * | 2008-01-31 | 2009-08-06 | Daiichi Sankyo Company, Limited | ベンジルフェニルグルコピラノシド誘導体 |
DE102008017590A1 (de) | 2008-04-07 | 2009-10-08 | Merck Patent Gmbh | Glucopyranosidderivate |
US7767651B2 (en) | 2005-01-28 | 2010-08-03 | Chugai Seiyaku Kabushiki Kaisha | Spiroketal derivatives and use thereof as diabetic medicine |
WO2011039338A2 (en) | 2009-10-02 | 2011-04-07 | Sanofi-Aventis | Use of compounds with sglt-1/sglt-2 inhibitor activity for producing medicaments for treatment of bone diseases |
WO2011051864A1 (en) | 2009-11-02 | 2011-05-05 | Pfizer Inc. | Dioxa-bicyclo[3.2.1]octane-2,3,4-triol derivatives |
WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
EP2774619A1 (de) | 2013-03-04 | 2014-09-10 | BioActive Food GmbH | Zusammensetzung zur Behandlung von hyperglykämischen Erkrankungen |
US9061060B2 (en) | 2008-07-15 | 2015-06-23 | Theracos Inc. | Deuterated benzylbenzene derivatives and methods of use |
EP2944311A1 (de) | 2014-05-16 | 2015-11-18 | BioActive Food GmbH | Kombination von biologisch aktiven Substanzen zur Behandlung von hyperglykämischen Erkrankungen |
US9573959B2 (en) | 2013-03-14 | 2017-02-21 | Msd International Gmbh | Methods for preparing SGLT2 inhibitors |
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CN1020944C (zh) | 1990-01-30 | 1993-05-26 | 阿图尔-费希尔股份公司费希尔厂 | 紧固件 |
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US7371732B2 (en) * | 2003-12-22 | 2008-05-13 | Boehringer Ingelheim International Gmbh | Glucopyranosyloxy-substituted aromatic compounds, medicaments containing such compounds, their use and process for their manufacture |
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JP2008524162A (ja) | 2004-12-16 | 2008-07-10 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | グルコピラノシル置換ベンゼン誘導体、該化合物を含む薬物、その使用及びその製造方法 |
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2001
- 2001-11-20 WO PCT/JP2001/010115 patent/WO2002044192A1/ja active Application Filing
- 2001-11-20 EP EP01998555A patent/EP1344780A4/en not_active Withdrawn
- 2001-11-20 AU AU2002223127A patent/AU2002223127A1/en not_active Abandoned
- 2001-11-20 US US10/432,905 patent/US7053060B2/en not_active Expired - Fee Related
- 2001-11-20 JP JP2002546562A patent/JP4212891B2/ja not_active Expired - Fee Related
- 2001-11-20 CA CA002429833A patent/CA2429833A1/en not_active Abandoned
- 2001-11-29 PE PE2001001204A patent/PE20020573A1/es not_active Application Discontinuation
- 2001-11-29 TW TW090129522A patent/TWI290556B/zh not_active IP Right Cessation
- 2001-11-29 AR ARP010105567A patent/AR034280A1/es not_active Application Discontinuation
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2004
- 2004-11-02 US US10/978,413 patent/US7129381B2/en not_active Expired - Fee Related
- 2004-11-02 US US10/978,331 patent/US20050113315A1/en not_active Abandoned
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EP1367060A1 (en) * | 2001-02-14 | 2003-12-03 | Kissei Pharmaceutical Co., Ltd. | Glucopyranosyloxybenzylbenzene derivatives and medicinal use thereof |
EP1367060A4 (en) * | 2001-02-14 | 2004-04-14 | Kissei Pharmaceutical | GLUCOPYRANOSYLOXYBENZYLBENZENE DERIVATIVES AND THEIR MEDICAL USE |
US7541341B2 (en) | 2001-02-14 | 2009-06-02 | Kissei Pharmaceutical Co., Ltd. | Glucopyranosyloxybenzylbenzene derivatives and medicinal use thereof |
WO2004050122A1 (ja) * | 2002-12-04 | 2004-06-17 | Kissei Pharmaceutical Co., Ltd. | 高血糖症に起因する疾患の予防又は治療剤 |
JP2004196788A (ja) * | 2002-12-04 | 2004-07-15 | Kissei Pharmaceut Co Ltd | ベンジルフェノール誘導体、それを含有する医薬組成物およびその医薬用途 |
JP4651934B2 (ja) * | 2002-12-04 | 2011-03-16 | キッセイ薬品工業株式会社 | ベンジルフェノール誘導体、それを含有する医薬組成物およびその医薬用途 |
US7288528B2 (en) | 2002-12-12 | 2007-10-30 | Sanofi-Aventis Deutschland Gmbh | Aromatic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof |
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JP2006510644A (ja) * | 2002-12-12 | 2006-03-30 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 新しい複素環フルオログリコシド誘導体、該化合物を含有する医薬品、およびその使用 |
JP4806193B2 (ja) * | 2002-12-12 | 2011-11-02 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 新しい複素環フルオログリコシド誘導体、該化合物を含有する医薬品、およびその使用 |
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JP2007518682A (ja) * | 2003-08-01 | 2007-07-12 | 田辺製薬株式会社 | 新規化合物 |
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JPWO2005095429A1 (ja) * | 2004-03-31 | 2008-02-21 | キッセイ薬品工業株式会社 | フェノール誘導体、それを含有する医薬組成物及びその医薬用途 |
US7767651B2 (en) | 2005-01-28 | 2010-08-03 | Chugai Seiyaku Kabushiki Kaisha | Spiroketal derivatives and use thereof as diabetic medicine |
JP2006232825A (ja) * | 2005-01-31 | 2006-09-07 | Tanabe Seiyaku Co Ltd | 医薬組成物 |
WO2007128761A2 (de) | 2006-05-04 | 2007-11-15 | Boehringer Ingelheim International Gmbh | Verwendungen von dpp iv inhibitoren |
EP2351568A2 (de) | 2006-05-04 | 2011-08-03 | Boehringer Ingelheim International GmbH | Verwendungen von dpp iv Inhibitoren |
WO2007147478A1 (de) | 2006-06-23 | 2007-12-27 | Merck Patent Gmbh | 3 -amino- imidazo [1, 2-a] pyridinderivate als sglt inhibitoren |
WO2008016132A1 (en) | 2006-08-04 | 2008-02-07 | Daiichi Sankyo Company, Limited | Benzyl phenyl glucopyranoside derivative |
EP2325182A1 (en) | 2006-12-06 | 2011-05-25 | Glaxosmithkline LLC | Bicyclic compounds and use as antidiabetics |
WO2008070692A2 (en) | 2006-12-06 | 2008-06-12 | Smithkline Beecham Corporation | Bicyclic compounds and use as antidiabetics |
DE102007008420A1 (de) | 2007-02-21 | 2008-08-28 | Merck Patent Gmbh | Benzimidazolderivate |
WO2009049731A1 (de) | 2007-10-11 | 2009-04-23 | Merck Patent Gmbh | Imidazo [ 1, 2 -a] pyrimidinderivate zur behandlung von erkrankungen wie diabetes |
DE102007048716A1 (de) | 2007-10-11 | 2009-04-23 | Merck Patent Gmbh | Imidazo[1,2-a]pyrimidinderivate |
WO2009096503A1 (ja) * | 2008-01-31 | 2009-08-06 | Daiichi Sankyo Company, Limited | ベンジルフェニルグルコピラノシド誘導体 |
WO2009124638A1 (de) | 2008-04-07 | 2009-10-15 | Merck Patent Gmbh | Glucopyranosidderivate |
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US9061060B2 (en) | 2008-07-15 | 2015-06-23 | Theracos Inc. | Deuterated benzylbenzene derivatives and methods of use |
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WO2011051864A1 (en) | 2009-11-02 | 2011-05-05 | Pfizer Inc. | Dioxa-bicyclo[3.2.1]octane-2,3,4-triol derivatives |
WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
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US9573959B2 (en) | 2013-03-14 | 2017-02-21 | Msd International Gmbh | Methods for preparing SGLT2 inhibitors |
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WO2023222144A1 (zh) * | 2022-05-18 | 2023-11-23 | 上海科利生物医药有限公司 | 一类硫代糖苷列净类似物及其制备方法和应用 |
Also Published As
Publication number | Publication date |
---|---|
AU2002223127A1 (en) | 2002-06-11 |
EP1344780A1 (en) | 2003-09-17 |
CA2429833A1 (en) | 2002-06-06 |
JP4212891B2 (ja) | 2009-01-21 |
AR034280A1 (es) | 2004-02-18 |
US7129381B2 (en) | 2006-10-31 |
PE20020573A1 (es) | 2002-07-31 |
US20050059614A1 (en) | 2005-03-17 |
US7053060B2 (en) | 2006-05-30 |
EP1344780A4 (en) | 2004-01-28 |
US20050113315A1 (en) | 2005-05-26 |
TWI290556B (en) | 2007-12-01 |
JPWO2002044192A1 (ja) | 2004-04-02 |
US20040063170A1 (en) | 2004-04-01 |
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