Classifications

• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
  • A61K35/66—Microorganisms or materials therefrom
  • A61K35/74—Bacteria
  • A61K35/741—Probiotics
  • A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
  • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
• • C—CHEMISTRY; METALLURGY
  • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
  • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
  • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
  • C12N1/20—Bacteria; Culture media therefor
• • C—CHEMISTRY; METALLURGY
  • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
  • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
  • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
  • C12N1/20—Bacteria; Culture media therefor
  • C12N1/205—Bacterial isolates
• • C—CHEMISTRY; METALLURGY
  • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
  • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
  • C12R2001/00—Microorganisms ; Processes using microorganisms
  • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
  • C12R2001/07—Bacillus

Definitions

• ⁇ e ⁇ ⁇ e ⁇ i ⁇ d of ⁇ uzhayuschey s ⁇ edy (from v ⁇ zdu ⁇ a, ⁇ edme ⁇ v u ⁇ da, ⁇ b ⁇ lny ⁇ zhiv ⁇ ny ⁇ , ⁇ ⁇ e ⁇ s ⁇ nala and d ⁇ ugi ⁇ is ⁇ chni ⁇ v) in ⁇ ganizm zhiv ⁇ ny ⁇ m ⁇ gu ⁇ ⁇ ada ⁇ ⁇ azlichnye ⁇ a ⁇ gennye and usl ⁇ vn ⁇ ⁇ a ⁇ gennye mi ⁇ ganizmy (en ⁇ e ⁇ a ⁇ gennye ⁇ ishechnye ⁇ al ⁇ ch ⁇ i, s ⁇ a- ⁇ il ⁇ i, ⁇ ei, ⁇ lebsielly 'and salm ⁇ nell
• the drugs are more effective for the treatment and treatment of gastrointestinal diseases of the living from vascular microculture.
• Eti ⁇ réelle -2- Injuries are at risk of physical injury to the stomach and the stomach, which is associated with gastrointestinal disease, ⁇ réelle ⁇ , for example ⁇ ,
• the indications indicated include one type of microorganism that does not provide a wide range of its antagonistic features.
• the basic task of the invention was to alter the biomass of bacteria and use new strains of microbial diseases to treat medications for the treatment of patients
• the quick link is desirable with a dry link.
• the culture produces glucose, arabinosis, beckoning, and the formation of an acid without gas.
• the operation of Facebook - Positive is positive.
• the culture does not produce gas from ⁇ 0 3 under anaerobic conditions; it does not produce arginine dihydrogenase.
• the crop grows in a environment that contains 7% of ya
• a meat and poultry bouillon is used to produce a small-film, sometimes with an extra-thick film.
• the culture is exploring catalase.
• the product is available on the market.
• the inventive product provides a pure, crystallized dry mass of light and non-volatile light that is not consumable to us.
• the bulk for water is not more than 5%.
• the product is emitted in glass ampoules with a content of 250 mg of dry substance (300-400 milliliters of microcells) or in glass flasks with a content of 500 mg (600 mg).
• the claimed ⁇ e ⁇ a ⁇ a ⁇ m ⁇ zhe ⁇ by ⁇ is ⁇ lz ⁇ van in ⁇ aches ⁇ ve s ⁇ eds ⁇ va ⁇ ila ⁇ i ⁇ i or ⁇ aches ⁇ ve s ⁇ eds ⁇ va treatment ⁇ s ⁇ y ⁇ zhelud ⁇ chn ⁇ - ⁇ ishechny ⁇ zab ⁇ levany m ⁇ l ⁇ dnya ⁇ a sels ⁇ - ⁇ zyays ⁇ venny ⁇ zhiv ⁇ ny ⁇ (disba ⁇ e ⁇ i ⁇ za, ⁇ liba ⁇ e ⁇ i ⁇ za, salm ⁇ nelleza, ⁇ azlichny ⁇ d ⁇ ugi ⁇ ⁇ s ⁇ y ⁇ zhelud ⁇ chn ⁇ - ⁇ ishechny ⁇ zab ⁇ levany sels ⁇ zyays venny ⁇ zhiv ⁇ ny ⁇ , vyzvanny ⁇ ⁇ a- ⁇ gennymi and usl ⁇ vn ⁇ pathogenic microorganisms).
• test results of the claimed product showed that out of 328 newborn calves, which were purchased by the claimed device, 19 of them had any injuries. ⁇ live group of 185 live
• the claimed medication was changed to 284 calves with various gastrointestinal diseases
• the inventive process was designated as the next one.
• Compound ampoules 300-400 milligrams of micro-cells were mixed in one milk or water, they were cooled and cooled to 25–30 ° C, and they were allowed to cool.
• the claimed preparation showed a high therapeutic and preventive effect.
• the product is characterized by a high rate of antagonism to the static response to various types of microorganisms - pathogens.
• the product helps to increase the protective reactions of the organism of animals (induction of the endogenous interactions,
• the claimed process is as follows.
• ⁇ Brass As a filling medium, use a mixture of a quick-release mixture of quick-release or gelatin with sugar or glucose. The resulting mixture is poured into a stylish ampoule 1 and placed in a corner, a cracker for 24 hours at a temperature not exceeding -20 ° C. The product is licensed for at least 44 hours and operating at -20 ° to + 20 ° ⁇ . After filizirovaniya ampoules solder. The inventive preparation keeps the activity and the duration of the storage for at least 2 years.
• the test for harmlessness leads to the following test: when administered directly, at least 5 mice weighing 18-22 grams are much more lively than the mouse, but the weight is very good. on the fifth day of observation.
• the conversion of speci fi c activity is carried out by the following process. Researches the antagonistic properties of -10- sections of microcultures included in the composition of the drug, in addition to testing, the number of tests carried out by the Party is limited,
• test results are presented in the table. For example, 2.
• the inventive product is of the following composition, in% (%): biomass strain . ⁇ . ⁇ admir ⁇ transaction ⁇ ⁇ ⁇ £ ⁇ -2336 20 35 5th gelatin solution. 21 sugar 4 -II-

Landscapes

• Health & Medical Sciences (AREA)
• Life Sciences & Earth Sciences (AREA)
• Chemical & Material Sciences (AREA)
• Engineering & Computer Science (AREA)
• Organic Chemistry (AREA)
• Bioinformatics & Cheminformatics (AREA)
• Zoology (AREA)
• Biotechnology (AREA)
• Medicinal Chemistry (AREA)
• General Health & Medical Sciences (AREA)
• Genetics & Genomics (AREA)
• Microbiology (AREA)
• Wood Science & Technology (AREA)
• Biochemistry (AREA)
• Public Health (AREA)
• General Engineering & Computer Science (AREA)
• Virology (AREA)
• Tropical Medicine & Parasitology (AREA)
• Biomedical Technology (AREA)
• Mycology (AREA)
• Veterinary Medicine (AREA)
• Pharmacology & Pharmacy (AREA)
• Animal Behavior & Ethology (AREA)
• Chemical Kinetics & Catalysis (AREA)
• Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
• General Chemical & Material Sciences (AREA)
• Molecular Biology (AREA)
• Epidemiology (AREA)
• Medicines Containing Material From Animals Or Micro-Organisms (AREA)
• Micro-Organisms Or Cultivation Processes Thereof (AREA)
• Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Priority Applications (5)

Applications Claiming Priority (1)

Publications (1)

Family

ID=21617080

Family Applications (1)

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Cited By (5)

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Citations (3)

• 1987
  • 1987-02-24 DE DE873790919T patent/DE3790919T1/de not_active Withdrawn
  • 1987-02-24 WO PCT/SU1987/000024 patent/WO1988006619A1/ru not_active Ceased
  • 1987-02-24 JP JP62502918A patent/JPH01502340A/ja active Pending
• 1988
  • 1988-02-24 CH CH4117/88A patent/CH674149A5/de not_active IP Right Cessation
  • 1988-10-07 GB GB8823554A patent/GB2209343B/en not_active Expired - Fee Related

Patent Citations (3)

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