WO1984004885A1 - Compositions for cosmetic, health- and body-preserving use - Google Patents

Compositions for cosmetic, health- and body-preserving use Download PDF

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Publication number
WO1984004885A1
WO1984004885A1 PCT/HU1984/000036 HU8400036W WO8404885A1 WO 1984004885 A1 WO1984004885 A1 WO 1984004885A1 HU 8400036 W HU8400036 W HU 8400036W WO 8404885 A1 WO8404885 A1 WO 8404885A1
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WO
WIPO (PCT)
Prior art keywords
elements
blood
waters
compositions
natural
Prior art date
Application number
PCT/HU1984/000036
Other languages
English (en)
French (fr)
Inventor
Laszlo Dede
Laszlone Dede
Laszlo Bogdany
Laszlone Bodgany
Original Assignee
Caola Kozmetikai
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU831991A external-priority patent/HU190723B/hu
Priority claimed from HU317683A external-priority patent/HU195727B/hu
Application filed by Caola Kozmetikai filed Critical Caola Kozmetikai
Priority to JP59502414A priority Critical patent/JPS60501506A/ja
Publication of WO1984004885A1 publication Critical patent/WO1984004885A1/en
Priority to FI850354A priority patent/FI82598C/fi
Priority to DK47885A priority patent/DK47885A/da
Priority to SU864027297A priority patent/RU2027431C1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/965—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of inanimate origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/004—Aftersun preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/008—Preparations for oily hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth

Definitions

  • This invention relates to cosmetic, health- and body-preserving compositions of high biological value, promoting the restoration of the cells and of that the skin, optimizing the biological processes occurring in the skin cells and providing the most preferable function of the enzyme system of the cells connected with the age of the organism.
  • the aim of the invention is to provide the restoration and preservation of the cells and the skin by using natural substances.
  • this aim is accomplished by treating proteins, suitably prepared from the blood or from the elements thereof with inorganic materials occurring as trace elements in the organism, or with natural, river-, lake-, sea-, mineral and medicinal waters, with inorganic materials obtained from these waters, by transforming the materials obtained to various cosmetic, healthand body-preserving compositions and by using those for serving these purposes.
  • the disorders arising from the deficiency of trace elements exert a general influence on the organism and hence also on the condition of the skin which is most striking for the observer.
  • the skin is a highly differentiated organ and its condition has a decisive influence on the aesthetic appearance of a man.
  • the trace elements are only capable of playing their role in the organism, in the skin cell3 when they can be coupled with a so-called carrier molecule transferring these elements to the site of action and thus providing the incorporation into the appropriate enzyme.
  • carrier molecules are in general proteins, obtained particularly from the blood or from the blood plasma, respectively. The eicact mechanism of this process is not known at present, it is understood however, that the connection of the trace element with a protein has a decisive importance in a multi-step process.
  • Silicium plays an important role in the structural development of both the collagenous and cartilaginous tissues.
  • a number of other ones, such as selenium as well as sulphur, sulphides, vanadium and nickel also possess important roles. Practically all inorganic materials are significant for the optimum function of a living cell, which is not surprising while considering that all these materials were present in the primary ocean, at the appearance of the life.
  • an inorganic substance, trace element or ion can get into the active transfer by being bound to a carrier protein on the one side /outer side/ of the cell .membrane Where a carrier-substrate complex is formed. This complex penetrates the membrane, then the carrier protein leaves the substrate on the other side of the membrane and returns to the membrane surface.
  • carrier molecules are the plasma proteins, transferrin,. alpha-microglobulins, transmangin, nicke loplasmins, etc.
  • the number and nature of these substances are not exactly known at present, their existence and roles are, however, well demonstrated.
  • the trace elements, inorganic salts and ions as such cannot freely diffuse through the skin into the living organism and the cells to a sufficient extent and cannot be bound to the enzymes; this occurs only by the aid of the carrier molecules.
  • These carriers can specifically transfer only a single, defined trace element to the site of the action and it can be supposed that these carriers are present in the blood.
  • the aim of this invention is to use the plasma proteins as a whole by treating those with trace elements, mineral, medicinal, natural waters and with the materials thereof to obtain compositions possessing a satisfactory activity.
  • compositions can be obtained which show an extraordinarily outstanding activity for the care of skin, for the therapy of rheumatic pains, for improvement of the hair quality, restoration of the hair bulbs as well as for the treatment of skin disorders and eczematous symptoms caused by detergents, by treating the proteins, e.g. prepared from the blood or blood elements with the appropriate trace elements and optionally by heating the mixture obtained.
  • Example 6 The action of the cream described in Example 6 was studied by using the adjuvant arthritis test on Long-Evans rats to observe a possible measurable effect of a cosmetic containing plasma proteins treated with medicinal water or with materials obtained therefrom on the alteration of the rat arthritis.
  • the rats under test were treated with a cream containing 1 or 5 per cent, respectively, of phenylbutazone known as one of the best anti-arthritic agents at present.
  • the arthritis was induced by injecting "Ravenal" /Mycobacterium tuberculosis in a concentration of 0.2 mg/kg, in an amount of 0.1 ml/paw, in a paraffin oil suspension/ to the right posterior paw of the rat.
  • the left posterior and both anterior paws of the animals were treated with the cream daily once for three weeks, i.e. 16 times in the course of the experiment.
  • the evaluation was made on the basis of the volume alteration of the left posterior paw.
  • a generalization of the arthritis was indicated by the swelling of the joints of the legs./
  • the leg use and physical state of the animals, as compared to the controls, were also scored. /This gave an information about the mo bility of the arthritic rats./
  • compositions of the invention are also preferably be used for the treatment of psoriasis when the appropriate medicinal water is chosen as an aqueous phase and mixed with the protein component.
  • Such medicinal water components are e.g. the waters of Harkány or Hajduszoboszl ⁇ as described in Examples 1 and 3.
  • Harkány and Héviz - as described in Examples 20 and 22, respectively, the restoration of hair bulbs is promoted and the hair fattening is diminished.
  • Example 24 enhances the restoration of skin damaged by sunburn and exerts a beneficial effect on milder household burn injuries.
  • compositions of the invention are intensified when in addition to or instead of medicinal waters, the mixtures of plant extracts and/or plant juices with medicinal waters, the mixtures of natural waters and/or extracts and the solutions thereof enriched with the required trace elements are used as aqueous phases of the compositions of the invention.
  • the proteins are suitable treated wich noble metal salts and with the solutions thereof in water and/or inmedicinal waters as illustrated by Example 2.
  • the compositions and embodiments of the invention are illustrated by the following non-limiting Examples.
  • Example 1 A mixture containing 137.5 g of white petrolatum /vaseline/, 82.5 g of cetyl alcohol, 27.5 g of paraffin oil and 27.5 g of Tween 60 is heated to 80 °C to form the fatty phase of the composition. Meanwhile, 10 g of plasma protein prepared from cattle blood plasma are swollen in 200 ml of the medicinal water of Harkany and the mixture is heat-treated at 112 °C for 90 minutes. After the treatment v/ith the medicinal water, the protein is cooled to 60 °C and mixed to the fatty phase kept at 80 °C.
  • Example 2 The process described in Example 1 is followed, except that 1 mg of gold /III/-trichloride is added to the plasma protein before or after the heat treatment.
  • Example 3 The process described in Example 1 or 2 is followed, except that the medicinal water of Hajduszoboszl ⁇ is used as an aqueous phase.
  • Example 4 The process described in Example 1 is followed, except that the medicinal water of Hajduszoboszl ⁇ is used as an aqueous phase.
  • Example 5 The process described in Example 1 or 2 is followed, except that the medicinal water of Parad is used as an aqueous phase.
  • Example 6 The process described in Example 1 is followed, except that the plasma protein is treated with 200 ml of the medicinal water arising from the Lukács-bath /Budapest/ which contain 1 mg of ferrous sulphate, 1 mg of cupric sulphate, 0.5 mg of nickelous sulphate, 1 mg of zinc sulphate and 0.5 mg of cobaltic chloride added previously.
  • Example 9 The process described in Examples 1 to 7 is followed, except that the natural water of Balaton is used as an aqueous phase.
  • Example 10 The process described in Example 1 is followed, except that the plasma protein is heat-treated with 200 ml of distilled water and then 600 ml of sea-water, e.g. of the water of the Aegean Sea is used for preparing the cream.
  • Example 10 The process described in Example 1 is followed, except that the plasma protein is heat-treated with 200 ml of distilled water and then 600 ml of sea-water, e.g. of the water of the Aegean Sea is used for preparing the cream.
  • Example 10 The process described in Example 1 is followed, except that the plasma protein is heat-treated with 200 ml of distilled water and then 600 ml of sea-water, e.g. of the water of the Aegean Sea is used for preparing the cream.
  • Example 11 The process described in Example 1 is followed, except that the plasma protein Is treated with the medicinal water in the presence of 2 mg of zinc sulphate.
  • Example 12 The process described in Example 1 is followed, except that, instead of the medicinal water a water is used which contains in 1 ml each 5 /ug of copper, 5 /ug of iron, 10 /ug of zinc, 2 /ug of cobalt, 1 /ug of nickel, 20 /ug of magnesium and 20 /ug of calcium.
  • Example 14 The process described in Example 1 is followed, except that carrot juice is used as an aqueous phase.
  • Example 15 The process described in Examples 1 to 6 is followed, except that apple vine neutralized by sodium hydrogen carbonate is used as an aqueous phase.
  • Example 16 The process described in Examples 1 to 6 is followed, except that a fruit juice, e.g. apple juice is used as an aqueous phase.
  • a fruit juice e.g. apple juice
  • Example 18 80 ml of water and 2 g of sodium hydrogen carbonate are added to 20 ml of swine blood, then the mixture is kept at 120 °C for 1 hour. The material obtained is filtered and 700 ml of the medicinal water of Harkány are added to the filtrate. The aqueous solution obtained is worked up to a cream in a manner known in the art to give an excellent, hydratating and skin-restoring /skin-preserving/ cosmetic which is also useful for alleviating rheumatic pains.
  • Example 18 80 ml of water and 2 g of sodium hydrogen carbonate are added to 20 ml of swine blood, then the mixture is kept at 120 °C for 1 hour. The material obtained is filtered and 700 ml of the medicinal water of Harkány are added to the filtrate. The aqueous solution obtained is worked up to a cream in a manner known in the art to give an excellent, hydratating and skin-restoring /skin-preserving/ cosmetic which is also useful for alleviating r
  • Example 20 The plasma protein prepared from 10 g of swine blood is treated with 200 ml of the medicinal water of Héviz at 120 oC. for 1 hour. To the solution obtained, 300 ml of the natural medicinal water of Héviz are added, the mixture is fille d to ampoules of 2 ml volume and sterilized after sealing. This ampouled composition is suitable to the preservation of the skin by manual infriction or by iontophoresis.
  • Example 21 2 mg of ferrous sulphate, 1 mg of manganous chloride, 1 mg of cupric sulphate, 1 mg of zinc sulphate and the extract prepared from 1 g of camomile with 20 ml of hot water are added to 100 ml of native cattle blood plasma. The mixture is heated to 80 °C under intensive stirring to give a jelly-like material with a highly hydratating and skin-restoring /skin-preserving/ effect.
  • Example 22 The process described in Example 20 or 21 is followed, except that instead of the medicinal water of Héviz, an 1 : 1 mixture containing the medicinal water of Harkany and Kajduszoboszl ⁇ is used.
  • Example 23 2 mg of ferrous sulphate, 1 mg of manganous chloride, 1 mg of cupric sulphate, 1 mg of zinc sulphate and the extract prepared from 1 g of camomile with 20 ml of hot water are added to 100 ml of native cattle blood plasma. The mixture is heated to 80 °C under intensive stirring to give a
  • a plasma protein powder prepared from 10 g of cattle blood 200 ml of the medicinal water of Harkany kept at 70°C are added and the mixture is heated at 112 °C for 90 minutes. After cooling, 70 ml of natural medicinal water of Harkány, 30 g of Alfozide KT-25, 30 g of Hala betaine, 570 g of sodium lauryl ether sulphate, 20 g of Alfid-D-11, 2 g of Alphasept (a preservative), 10 g of polyethyleneglycol M-200 and 10 ml of 96 % ethanol are added to the mixture to give an excellent refreshing, skin-restoring foam bath which also promotes the restoration of the rheumatic parts of the body.
  • Example 24 A Plasma protein prepared from 10 g of swine-blood is treated with 200 ml of the medicinal water of Harkany at 120 °C for 1 hour, then 125 ml of the medicinal water of Harkány and 125 ml of the medicinal water of the Lukács-bath /Budapest/ are added to the solution obtained. This mixture is supplemented with an appropriate preservative and used in spray form to treat the skin injuries caused by sunburn.
  • Example 2-5 A Plasma protein prepared from 10 g of swine-blood is treated with 200 ml of the medicinal water of Harkany at 120 °C for 1 hour, then 125 ml of the medicinal water of Harkány and 125 ml of the medicinal water of the Lukács-bath /Budapest/ are added to the solution obtained. This mixture is supplemented with an appropriate preservative and used in spray form to treat the skin injuries caused by sunburn.
  • Example 2-5 A Plasma protein prepared from 10 g of
  • a plasma protein prepared from 10 g of rabbit blood is treated with 200 ml of the medicinal water of Hajduszoboszl ⁇ at 112 °C for 90 minutes, then 300 ml of the medicinal water of Balf and 50 ml of sea-water are added to the hot solution. Then 92 g of Alfozide KT-25, 75 g of Zala betaine, 190 g of sodium lauryl ether sulphate, 10 g of Alfid-D-11 and 2 g of Alphasept are added to the mixture to give an outstanding hair shampoo promoting tho restoration of the hair bulbs and the steady hair growth.
  • a plasma protein powder prepared from 10 g of cattle blood is swollen with 200 ml of the medicinal water of Harkány while stirring and kept at 112 °C for 1 hour.
  • 300 ml of a medicinal water of Harkány are added which contain 0.2 mg of ferrous sulphate, 0.2 mg of zinc sulphate, 0.2 mg of cupric sulphate, 0.1 mg of nickelous sulphate and 0.1 mg of cobaltic chloride.
  • the mixture obtained is filled to ampoules of 2 ml volume and sterilized by heat.
  • This composition excellently inhibits the fattening of the hair by infriction into the hair and hair skin and promotes the restoration of the hair bulbs.
  • the composition also inhibits the seborrhea of the hair.
  • a plasma protein prepared from 10 g of swine blood is transformed to a solution by treating with 100 ml of the medicinal water of Hajduszoboszl ⁇ and 100 ml of the medicinal water of Harkány at 120 °C.
  • g of cosmetic lanolin, 20 g of propyleneglycol and 3 g of Fipagin M is added.
  • the mixture is supplemented with 1100 ml of medicinal water of Hajduszoboszl ⁇ kept at 60°C and with 5 g of potassium hydroxide and stirred until cool.
  • This composition is excellently useful as a hand-preserving balsam to restore the eczematous skin disorders caused by e.g. detergents.
  • 142 g of stearin is saponified by 23.5 g of potassium hydroxide in 500 ml of dis tilled water at 30°C , then a solution prepared from 10 g of plasma protein with 200 ml of the medicinal water of Héviz at 160 °C, as well as 100 g of sodium lauryl ether sulphate, 100 g of glycerol, 3 g of llipagin M preservative agent are added and stirred until cool.
  • An outstanding cleaning agent is obtained which inhibits the damaging /injury/ and desiccation of the skin.
  • Example 32 The process described in Example
  • Example 31 or 32 The process described in Example 31 or 32 is followed, except that 1 mg of ferrous sulphate, 1 mg of zinc sulphate, 1 mg of cupric sulphate, 0.5 mg of nickelous sulphate, 0.5 mg of manganous sulphate and 0.2 mg of ammonium molybdate are dissolved in the aqueous phase before mixing.
  • Example 34 A salt mixture obtained by evaporating

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
PCT/HU1984/000036 1983-06-03 1984-06-01 Compositions for cosmetic, health- and body-preserving use WO1984004885A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP59502414A JPS60501506A (ja) 1983-06-03 1984-06-01 化粧用、健康維持用及び身体保護用組成物
FI850354A FI82598C (fi) 1983-06-03 1985-01-28 Kosmetiska kompositioner avsedda foer utvaertesbruk.
DK47885A DK47885A (da) 1983-06-03 1985-02-01 Kompositioner til brug som kosmetiske, sundhedsbevarende og kropsbeskyttende midler
SU864027297A RU2027431C1 (ru) 1983-06-03 1986-04-08 Средство для ухода за кожей

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU831991A HU190723B (en) 1983-06-03 1983-06-03 Cosmetical composition containing protein-trace element adducts and process for producing them
HU317683A HU195727B (en) 1983-09-13 1983-09-13 Cosmetics based on medical, mineral or thermal water and process for production of the active substance

Publications (1)

Publication Number Publication Date
WO1984004885A1 true WO1984004885A1 (en) 1984-12-20

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Application Number Title Priority Date Filing Date
PCT/HU1984/000036 WO1984004885A1 (en) 1983-06-03 1984-06-01 Compositions for cosmetic, health- and body-preserving use

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CA (1) CA1243957A (enrdf_load_stackoverflow)
CH (1) CH677319A5 (enrdf_load_stackoverflow)
CS (1) CS252816B2 (enrdf_load_stackoverflow)
DE (1) DE3490279T1 (enrdf_load_stackoverflow)
DK (1) DK47885A (enrdf_load_stackoverflow)
ES (1) ES533050A0 (enrdf_load_stackoverflow)
FI (1) FI82598C (enrdf_load_stackoverflow)
FR (1) FR2546754B1 (enrdf_load_stackoverflow)
GB (1) GB2156216B (enrdf_load_stackoverflow)
GR (1) GR82188B (enrdf_load_stackoverflow)
NL (1) NL8420169A (enrdf_load_stackoverflow)
NO (1) NO850391L (enrdf_load_stackoverflow)
PL (1) PL248003A1 (enrdf_load_stackoverflow)
PT (1) PT78679B (enrdf_load_stackoverflow)
SE (1) SE8500470D0 (enrdf_load_stackoverflow)
SU (1) SU1718709A3 (enrdf_load_stackoverflow)
WO (1) WO1984004885A1 (enrdf_load_stackoverflow)
YU (1) YU95284A (enrdf_load_stackoverflow)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0217975A1 (de) * 1985-10-08 1987-04-15 Psori-Med Ag Salzmischung zur Behandlung der Schuppenflechte (Psoriasis) und anderer Hautkrankheiten
EP0351766A3 (de) * 1988-07-19 1991-03-27 Vogt-Dembowski, Elisabeth, Dr. med. Dermatologisches Präparat
RU2131254C1 (ru) * 1994-07-22 1999-06-10 Л'Ореаль Применение воды с содержанием ионов менее 400 мг/л в косметической и/или дерматологической композиции, косметическая и/или дерматологическая композиция и способ обработки кожи
WO2000050045A3 (de) * 1999-02-26 2000-11-16 Chakravarty Adusumalli Injektionslösung enthaltend einer goldverbindung, calendula und belladonna extrakten zur behandlung von arthrosen
US6372791B1 (en) 2000-06-29 2002-04-16 Johnson & Johnson Consumer Companies, Inc. Method of promoting skin cell metabolism
US6432424B1 (en) 2000-06-29 2002-08-13 Johnson & Johnson Consumer Companies, Inc. Cosmetic compositions containing creatine, carnitine, and/or pyruvic acid
US6630175B1 (en) 2000-06-29 2003-10-07 Johnson & Johnson Consumer Companies, Inc. Method of reducing eye irritation
US6649176B1 (en) 2000-06-29 2003-11-18 Johnson & Johnson Consumer Companies, Inc. Compositions containing mineral water
DE10325158A1 (de) * 2003-05-28 2004-12-23 Coty B.V. Kosmetikum für die Remineralisierung und Anti-Alterungsbehandlung der Haut

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DE3327840C1 (de) * 1983-08-02 1984-09-20 Blendax Werke Schneider Co Hautpflegemittel
FR2587208B1 (fr) * 1985-09-19 1988-05-13 Scherninski Francois Lotion antichute et regeneratrice capillaire
WO1987005503A1 (en) * 1986-03-11 1987-09-24 Karoly Fabian Cosmetic compositions and process for preparing the same
FR2688133A1 (fr) * 1992-03-06 1993-09-10 Plantes Tropicales Lab Composition d'hygiene a base d'eau de mer.
FR2735021B1 (fr) * 1995-06-08 1998-02-27 Maugendre Renee Jane Procede de preparation d'eau de mer pour la desagregation du cerumen
FR2738742B1 (fr) * 1995-09-19 1997-11-14 Oreal Utilisation d'au moins une eau thermale de vichy en tant qu'antagoniste de substance p
RS20100392A3 (en) * 2010-09-06 2012-12-31 Pavlov, Aleksandar PROCEDURE FOR OBTAINING A HERBAL PREPARATION BASED ON AN EXTRACT OF A HERBAL MIXTURE FOR APPLICATION TO THE SKIN AND A HERBAL PREPARATION OBTAINED BY THIS PROCEDURE

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US4177261A (en) * 1977-01-03 1979-12-04 Thera Gesellschaft Fur Patentverwertung Mbh Pharmaceutical composition and method of stimulating blood circulation and wound healing
US4343793A (en) * 1980-03-10 1982-08-10 Max-Planck Gesellschaft Zur Forderung Der Wissenschaften Process for obtaining intact and viable leucocytes and thrombocytes from blood

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0217975A1 (de) * 1985-10-08 1987-04-15 Psori-Med Ag Salzmischung zur Behandlung der Schuppenflechte (Psoriasis) und anderer Hautkrankheiten
US4943432A (en) * 1985-10-08 1990-07-24 Biener Hans F Salt mixture for the treatment of psoriasis
EP0351766A3 (de) * 1988-07-19 1991-03-27 Vogt-Dembowski, Elisabeth, Dr. med. Dermatologisches Präparat
RU2131254C1 (ru) * 1994-07-22 1999-06-10 Л'Ореаль Применение воды с содержанием ионов менее 400 мг/л в косметической и/или дерматологической композиции, косметическая и/или дерматологическая композиция и способ обработки кожи
WO2000050045A3 (de) * 1999-02-26 2000-11-16 Chakravarty Adusumalli Injektionslösung enthaltend einer goldverbindung, calendula und belladonna extrakten zur behandlung von arthrosen
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CS252816B2 (en) 1987-10-15
ES8603258A1 (es) 1985-12-16
DE3490279T1 (de) 1985-05-15
FI82598C (fi) 1991-04-10
GB2156216A (en) 1985-10-09
FI82598B (fi) 1990-12-31
FI850354L (fi) 1985-01-28
PT78679B (en) 1986-07-11
CA1243957A (en) 1988-11-01
GB2156216B (en) 1987-03-25
NL8420169A (nl) 1985-04-01
SU1718709A3 (ru) 1992-03-07
DK47885D0 (da) 1985-02-01
FR2546754B1 (fr) 1987-12-18
PT78679A (en) 1984-07-01
DK47885A (da) 1985-02-04
FR2546754A1 (fr) 1984-12-07
GB8502534D0 (en) 1985-03-06
NO850391L (no) 1985-02-01
PL248003A1 (en) 1986-02-11
CH677319A5 (de) 1991-05-15
YU95284A (en) 1991-02-28
ES533050A0 (es) 1985-12-16
FI850354A0 (fi) 1985-01-28
SE8500470L (sv) 1985-02-01
CS414284A2 (en) 1987-03-12
SE8500470D0 (sv) 1985-02-01
GR82188B (enrdf_load_stackoverflow) 1984-12-13

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