UY37831A - Nuevos derivados de quinolina - Google Patents
Nuevos derivados de quinolinaInfo
- Publication number
- UY37831A UY37831A UY0001037831A UY37831A UY37831A UY 37831 A UY37831 A UY 37831A UY 0001037831 A UY0001037831 A UY 0001037831A UY 37831 A UY37831 A UY 37831A UY 37831 A UY37831 A UY 37831A
- Authority
- UY
- Uruguay
- Prior art keywords
- compounds
- preparation
- quinolina
- new derivatives
- pharmaceutical compositions
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 5
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000006806 disease prevention Effects 0.000 abstract 1
- 244000000013 helminth Species 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
Abstract
La invención abarca nuevos compuestos de quinolina de la fórmula general (I): en la cual A, R1, R2, R3, R4, R5, R6 y Q son como se definen en el presente, procedimientos para la elaboración de dichos compuestos, compuestos intermedios útiles para la elaboración de dichos compuestos, composiciones farmacéuticas y combinaciones que comprenden dichos compuestos y el uso de dichos compuestos para la elaboración de composiciones farmacéuticas para el tratamiento, control y/o prevención de enfermedades, en particular de infecciones con helmintos, como un único agente o en combinación con otros principios activos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17185001 | 2017-08-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY37831A true UY37831A (es) | 2019-02-28 |
Family
ID=59558299
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY0001037831A UY37831A (es) | 2017-08-04 | 2018-08-03 | Nuevos derivados de quinolina |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US11254661B2 (es) |
| EP (1) | EP3634959A1 (es) |
| JP (1) | JP7455294B2 (es) |
| KR (1) | KR20200036909A (es) |
| CN (1) | CN111132977B (es) |
| AU (1) | AU2018311019B2 (es) |
| BR (1) | BR112020002348A2 (es) |
| CA (1) | CA3071759A1 (es) |
| CL (1) | CL2020000301A1 (es) |
| CO (1) | CO2020001244A2 (es) |
| DO (1) | DOP2020000023A (es) |
| IL (1) | IL272156B2 (es) |
| MX (1) | MX2020001403A (es) |
| PH (1) | PH12020500257A1 (es) |
| SG (1) | SG11202000266VA (es) |
| TW (1) | TWI790263B (es) |
| UY (1) | UY37831A (es) |
| WO (1) | WO2019025341A1 (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3643711A1 (en) * | 2018-10-24 | 2020-04-29 | Bayer Animal Health GmbH | New anthelmintic compounds |
| BR112021012016A2 (pt) | 2018-12-18 | 2021-09-08 | Elanco Tiergesundheit Ag | Derivados bicíclicos |
| CN113490527A (zh) | 2018-12-18 | 2021-10-08 | 瑞士伊兰科动物保健有限公司 | 双环衍生物 |
| PE20220281A1 (es) * | 2019-03-19 | 2022-02-25 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos de aza-benzotiofeno y aza-benzofurano como antihelminticos |
| CA3141905A1 (en) * | 2019-06-07 | 2020-12-10 | Elanco Tiergesundheit Ag | Bicyclic derivatives for treating endoparasites |
| TW202120490A (zh) * | 2019-07-30 | 2021-06-01 | 德商拜耳動物保健有限公司 | 新穎異喹啉衍生物 |
| AU2020406093A1 (en) | 2019-12-18 | 2022-06-16 | Intervet International B.V. | Anthelmintic compounds comprising a quinoline structure |
| MX2022015038A (es) | 2020-05-29 | 2023-01-04 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos heterociclicos como anthelminticos. |
| AU2021384833A1 (en) | 2020-11-18 | 2023-06-15 | Elanco Tiergesundheit Ag | N-(2,3-dihydro-1,4-benzoxazin-4-yl)-3-isopropyl-7-(2,3,5-trifluorophenyl)benzo-thiophene-2-carboxamide derivatives and similar compounds for the treatment of heartworm infections |
| TW202237600A (zh) | 2020-12-04 | 2022-10-01 | 瑞士商禮藍動物保健股份有限公司 | 雙環衍生物 |
| CN116600807A (zh) | 2020-12-11 | 2023-08-15 | 英特维特国际股份有限公司 | 包含噻吩并吡啶结构的驱虫化合物 |
| EP4259606A1 (en) | 2020-12-11 | 2023-10-18 | Intervet International B.V. | Anthelmintic compounds comprising a pyridine structure |
| EP4148052A1 (en) * | 2021-09-09 | 2023-03-15 | Bayer Animal Health GmbH | New quinoline derivatives |
| TW202333665A (zh) | 2021-11-01 | 2023-09-01 | 德商百靈佳殷格翰維美迪加股份有限公司 | 驅蟲吡咯幷嗒𠯤化合物 |
| WO2023183437A1 (en) * | 2022-03-22 | 2023-09-28 | Sporos Biodiscovery, Inc. | Tead inhibitors and methods of use |
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| DE3639877A1 (de) | 1986-11-21 | 1988-05-26 | Bayer Ag | Hetarylalkyl substituierte 5- und 6-ringheterocyclen |
| US6559145B2 (en) | 2000-07-12 | 2003-05-06 | Pharmacia & Upjohn Company | Heterocycle carboxamides as antiviral agents |
| GB0213715D0 (en) | 2002-06-14 | 2002-07-24 | Syngenta Ltd | Chemical compounds |
| TWI312272B (en) | 2003-05-12 | 2009-07-21 | Sumitomo Chemical Co | Pyrimidine compound and pests controlling composition containing the same |
| GB0414438D0 (en) | 2004-06-28 | 2004-07-28 | Syngenta Participations Ag | Chemical compounds |
| TWI382020B (zh) | 2004-10-20 | 2013-01-11 | Kumiai Chemical Industry Co | ３-三唑基苯基硫醚衍生物及以其為有效成份之殺蟲、殺蟎、殺線蟲劑 |
| MX2007009168A (es) * | 2005-01-28 | 2007-08-14 | Janssen Pharmaceutica Nv | Compuestos antihelminticos. |
| CN102936221B (zh) | 2005-10-06 | 2014-09-10 | 日本曹达株式会社 | 桥联环状胺化合物以及有害生物防除剂 |
| JP2008214323A (ja) | 2007-03-08 | 2008-09-18 | Kyowa Hakko Kogyo Co Ltd | 皮膚疾患の治療及び／または予防剤 |
| JP5268461B2 (ja) | 2008-07-14 | 2013-08-21 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | Ｐｆ１３６４物質、その製造方法、生産菌株、及び、それを有効成分とする農園芸用殺虫剤 |
| CN101337937B (zh) | 2008-08-12 | 2010-12-22 | 国家农药创制工程技术研究中心 | 具有杀虫活性的n-苯基-5-取代氨基吡唑类化合物 |
| CN101337940B (zh) | 2008-08-12 | 2012-05-02 | 国家农药创制工程技术研究中心 | 具杀虫活性的含氮杂环二氯烯丙醚类化合物 |
| CN101715774A (zh) | 2008-10-09 | 2010-06-02 | 浙江化工科技集团有限公司 | 一个具有杀虫活性化合物制备及用途 |
| EP2184273A1 (de) | 2008-11-05 | 2010-05-12 | Bayer CropScience AG | Halogen-substituierte Verbindungen als Pestizide |
| GB0820344D0 (en) | 2008-11-06 | 2008-12-17 | Syngenta Ltd | Herbicidal compositions |
| WO2010066780A1 (en) | 2008-12-12 | 2010-06-17 | Syngenta Participations Ag | Spiroheterocyclic n-oxypiperidines as pesticides |
| EP2379076B1 (en) | 2008-12-23 | 2014-11-12 | The Trustees of Columbia University in the City of New York | Phosphodiesterase inhibitors and uses thereof |
| WO2011085575A1 (zh) | 2010-01-15 | 2011-07-21 | 江苏省农药研究所股份有限公司 | 邻杂环甲酰苯胺类化合物及其合成方法和应用 |
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| CN102391261A (zh) | 2011-10-14 | 2012-03-28 | 上海交通大学 | 一种n-取代噁二嗪类化合物及其制备方法和应用 |
| RU2014122035A (ru) * | 2011-11-02 | 2015-12-10 | Байер Интеллектуэль Проперти Гмбх | Соединения с нематоцидной активностью |
| TWI566701B (zh) | 2012-02-01 | 2017-01-21 | 日本農藥股份有限公司 | 芳烷氧基嘧啶衍生物及包含該衍生物作為有效成分的農園藝用殺蟲劑及其使用方法 |
| US9006257B2 (en) | 2012-02-09 | 2015-04-14 | Glenmark Pharmaceuticals S.A. | Bicyclic compounds as mPGES-1 inhibitors |
| WO2013144213A1 (en) | 2012-03-30 | 2013-10-03 | Basf Se | N-substituted pyridinylidene compounds and derivatives for combating animal pests |
| EP2647626A1 (en) | 2012-04-03 | 2013-10-09 | Syngenta Participations AG. | 1-Aza-spiro[4.5]dec-3-ene and 1,8-diaza-spiro[4.5]dec-3-ene derivatives as pesticides |
| US9282739B2 (en) | 2012-04-27 | 2016-03-15 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
| RU2627654C2 (ru) | 2012-04-27 | 2017-08-09 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Пестицидные композиции и относящиеся к ним способы |
| CN103232431B (zh) | 2013-01-25 | 2014-11-05 | 青岛科技大学 | 一种二卤代吡唑酰胺类化合物及其应用 |
| CN103109816B (zh) | 2013-01-25 | 2014-09-10 | 青岛科技大学 | 硫代苯甲酰胺类化合物及其应用 |
| WO2014158644A1 (en) | 2013-03-13 | 2014-10-02 | Dow Agrosciences Llc | Process for the preparation of triaryl rhamnose carbamates |
| CN105228448B (zh) | 2013-05-23 | 2019-03-01 | 先正达参股股份有限公司 | 桶混配制品 |
| CN103265527B (zh) | 2013-06-07 | 2014-08-13 | 江苏省农用激素工程技术研究中心有限公司 | 邻氨基苯甲酰胺化合物及其制备方法和应用 |
| CN103524422B (zh) | 2013-10-11 | 2015-05-27 | 中国农业科学院植物保护研究所 | 苯并咪唑衍生物及其制备方法和用途 |
| MX2016004942A (es) | 2013-10-17 | 2016-06-28 | Dow Agrosciences Llc | Procesos para la preparacion de compuestos plaguicidas. |
| EP3057429A4 (en) | 2013-10-17 | 2017-08-09 | Dow AgroSciences LLC | Processes for the preparation of pesticidal compounds |
| AR098475A1 (es) * | 2013-11-26 | 2016-06-01 | Bayer Cropscience Ag | Compuestos pesticidas y usos |
| TW201613866A (en) | 2014-07-07 | 2016-04-16 | Bayer Cropscience Ag | Process for preparing fluorinated iminopyridine compounds |
| UY36196A (es) * | 2014-07-25 | 2016-02-29 | Bayer Animal Health Gmbh | Compuestos para usar en el tratamiento antihelmíntico |
| KR101961581B1 (ko) | 2015-02-17 | 2019-03-22 | 닛뽕소다 가부시키가이샤 | 농약 조성물 |
| RU2018126105A (ru) | 2015-12-17 | 2020-01-17 | Астекс Терапьютикс Лимитед | Хинолин-3-карбоксамиды в качестве ингибиторов h-pgds |
| CN109890793B (zh) * | 2016-11-11 | 2022-11-18 | 拜耳动物保健有限责任公司 | 新的抗蠕虫药喹啉-3-甲酰胺衍生物 |
-
2018
- 2018-07-30 KR KR1020207005873A patent/KR20200036909A/ko not_active Application Discontinuation
- 2018-07-30 IL IL272156A patent/IL272156B2/en unknown
- 2018-07-30 CN CN201880064509.9A patent/CN111132977B/zh active Active
- 2018-07-30 AU AU2018311019A patent/AU2018311019B2/en active Active
- 2018-07-30 US US16/636,276 patent/US11254661B2/en active Active
- 2018-07-30 SG SG11202000266VA patent/SG11202000266VA/en unknown
- 2018-07-30 BR BR112020002348-5A patent/BR112020002348A2/pt unknown
- 2018-07-30 JP JP2020505351A patent/JP7455294B2/ja active Active
- 2018-07-30 WO PCT/EP2018/070552 patent/WO2019025341A1/en unknown
- 2018-07-30 CA CA3071759A patent/CA3071759A1/en active Pending
- 2018-07-30 MX MX2020001403A patent/MX2020001403A/es unknown
- 2018-07-30 EP EP18745626.4A patent/EP3634959A1/en active Pending
- 2018-08-02 TW TW107126871A patent/TWI790263B/zh active
- 2018-08-03 UY UY0001037831A patent/UY37831A/es not_active Application Discontinuation
-
2020
- 2020-02-03 CL CL2020000301A patent/CL2020000301A1/es unknown
- 2020-02-04 CO CONC2020/0001244A patent/CO2020001244A2/es unknown
- 2020-02-04 PH PH12020500257A patent/PH12020500257A1/en unknown
- 2020-02-04 DO DO2020000023A patent/DOP2020000023A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2020109388A3 (es) | 2021-11-30 |
| MX2020001403A (es) | 2020-03-09 |
| CN111132977A (zh) | 2020-05-08 |
| IL272156B2 (en) | 2023-09-01 |
| EP3634959A1 (en) | 2020-04-15 |
| CN111132977B (zh) | 2024-07-23 |
| WO2019025341A1 (en) | 2019-02-07 |
| KR20200036909A (ko) | 2020-04-07 |
| US11254661B2 (en) | 2022-02-22 |
| CL2020000301A1 (es) | 2020-07-31 |
| JP2020528921A (ja) | 2020-10-01 |
| AU2018311019B2 (en) | 2022-05-26 |
| RU2020109388A (ru) | 2021-09-07 |
| IL272156B1 (en) | 2023-05-01 |
| JP7455294B2 (ja) | 2024-03-26 |
| TW201920155A (zh) | 2019-06-01 |
| AU2018311019A1 (en) | 2020-01-30 |
| PH12020500257A1 (en) | 2020-09-14 |
| CO2020001244A2 (es) | 2020-02-18 |
| TWI790263B (zh) | 2023-01-21 |
| SG11202000266VA (en) | 2020-02-27 |
| DOP2020000023A (es) | 2020-02-28 |
| BR112020002348A2 (pt) | 2020-09-08 |
| CA3071759A1 (en) | 2019-02-07 |
| IL272156A (en) | 2020-03-31 |
| US20200377486A1 (en) | 2020-12-03 |
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Effective date: 20231110 |