UY33507A - Proceso para la preparacion de sales de enolato de 4-fluoro-2-hidroximetileno-3-oxo-butiratos - Google Patents

Proceso para la preparacion de sales de enolato de 4-fluoro-2-hidroximetileno-3-oxo-butiratos

Info

Publication number
UY33507A
UY33507A UY0001033507A UY33507A UY33507A UY 33507 A UY33507 A UY 33507A UY 0001033507 A UY0001033507 A UY 0001033507A UY 33507 A UY33507 A UY 33507A UY 33507 A UY33507 A UY 33507A
Authority
UY
Uruguay
Prior art keywords
fluoro
enolate salts
hydroximethylene
butirates
oxo
Prior art date
Application number
UY0001033507A
Other languages
English (en)
Inventor
Paul Hanselmann
Zaragoba Dorwald Florencio
Martina Dressel
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of UY33507A publication Critical patent/UY33507A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/58—Preparation of carboxylic acid halides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/58—Preparation of carboxylic acid halides
    • C07C51/62—Preparation of carboxylic acid halides by reactions not involving the carboxylic acid halide group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/14—Preparation of carboxylic acid esters from carboxylic acid halides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C07C69/12—Acetic acid esters
    • C07C69/14—Acetic acid esters of monohydroxylic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/716—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/716—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • C07C69/72—Acetoacetic acid esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids

Abstract

Sales de Enolato de 4-fluoro-2-hidroximetileno-3-oxobutiratos de la fórmula en donde R1 es aquilo C1-10, R2 yR3 son independientemente hidrógeno o flúor, M es un metal alcalino o alcalinotérreo, y n es 1 o 2, se preparan a partir de sales de Enolato de los 4 -fluoro -3-oxobutiratos correspondientes y el monóxido de carbono. Se pueden alquilatar o acilatar las sales de enolato de la fórmula I para obtener los éteres y estéres de enol correspondientes
UY0001033507A 2010-07-13 2011-07-12 Proceso para la preparacion de sales de enolato de 4-fluoro-2-hidroximetileno-3-oxo-butiratos UY33507A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP10007208 2010-07-13

Publications (1)

Publication Number Publication Date
UY33507A true UY33507A (es) 2012-01-31

Family

ID=43086152

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001033507A UY33507A (es) 2010-07-13 2011-07-12 Proceso para la preparacion de sales de enolato de 4-fluoro-2-hidroximetileno-3-oxo-butiratos

Country Status (15)

Country Link
US (1) US9156771B2 (es)
EP (1) EP2593420B1 (es)
JP (1) JP5911859B2 (es)
KR (1) KR101870462B1 (es)
CN (1) CN103153939B (es)
AR (1) AR082159A1 (es)
AU (1) AU2011278705A1 (es)
BR (1) BR112013000763A2 (es)
CA (1) CA2806717A1 (es)
ES (1) ES2610147T3 (es)
HK (1) HK1186172A1 (es)
HU (1) HUE033005T2 (es)
TW (1) TWI562985B (es)
UY (1) UY33507A (es)
WO (1) WO2012007142A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114105792B (zh) * 2022-01-14 2023-03-31 山东国邦药业有限公司 一种环丙沙星关键中间体的制备方法
CN114933543B (zh) * 2022-07-21 2022-10-28 山东国邦药业有限公司 一种3-环丙胺基-2-(2,4-二氯-5-氟苯甲酰基)丙烯酸甲酯的合成方法
CN115010753A (zh) * 2022-07-27 2022-09-06 南京工业大学 一种水相中制备磷酸化偕二氟二烯烃化合物的方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2394255A (en) * 1942-04-07 1946-02-05 American Cyanamid Co Formylacetic ester
US3637812A (en) * 1967-10-02 1972-01-25 Merck & Co Inc Acylation of reactive organic acid esters
DE2952070C2 (de) * 1979-12-22 1983-09-08 Dynamit Nobel Ag, 5210 Troisdorf Verfahren zur Herstellung von Alkaliformylessigsäurealkylester
JPS61152640A (ja) * 1984-12-26 1986-07-11 Daicel Chem Ind Ltd アルカリホルミルカルボン酸エステルの製法
JPH0822853B2 (ja) 1987-10-23 1996-03-06 三井東圧化学株式会社 ピラゾール−４−カルボン酸類およびその製造方法
US5093347A (en) 1991-01-28 1992-03-03 Monsanto Company 3-difluoromethylpyrazolecarboxamide fungicides, compositions and use
DE4142191A1 (de) * 1991-12-20 1993-06-24 Bayer Ag Verfahren zur herstellung von 3-alkoxy-acrylestern
US5616713A (en) * 1996-07-22 1997-04-01 Development Center For Biotechnology Process of preparing 2-hydroxymethyl-3,5-dimethyl-4-methoxypyridine
JP2004325727A (ja) * 2003-04-24 2004-11-18 Konica Minolta Medical & Graphic Inc 熱現像装置
WO2005123690A1 (de) 2004-06-18 2005-12-29 Basf Aktiengesellschaft 1-methyl-3-difluormethyl-pyrazol-4-carbonsäure-(ortho-phenyl)-anilide und ihre verwendung als fungizid
US7863460B2 (en) * 2005-02-25 2011-01-04 Sagami Chemical Research Center Process for producing 1-substituted-3-fluoroalkylpyrazole-4-carboxylate
JP2007326784A (ja) * 2006-06-06 2007-12-20 Sagami Chem Res Center １−置換−５−フルオロアルキルピラゾール−４−カルボン酸エステルの製造方法
CN101801906A (zh) * 2007-08-16 2010-08-11 索尔维公司 制备4-氟取代的3-氧代-烷酸酯的方法
UA102386C2 (ru) * 2008-02-29 2013-07-10 Басф Се Способ получения алкил-2-алкоксимэтилен-4,4-дифтор-3-оксобутиратов

Also Published As

Publication number Publication date
KR20130140603A (ko) 2013-12-24
AR082159A1 (es) 2012-11-14
EP2593420B1 (en) 2016-10-19
HK1186172A1 (zh) 2014-03-07
JP2013535430A (ja) 2013-09-12
TW201206879A (en) 2012-02-16
AU2011278705A1 (en) 2013-02-28
WO2012007142A1 (en) 2012-01-19
CA2806717A1 (en) 2012-01-19
EP2593420A1 (en) 2013-05-22
WO2012007142A8 (en) 2013-02-28
CN103153939A (zh) 2013-06-12
KR101870462B1 (ko) 2018-06-22
TWI562985B (en) 2016-12-21
US9156771B2 (en) 2015-10-13
ES2610147T3 (es) 2017-04-26
BR112013000763A2 (pt) 2016-05-24
CN103153939B (zh) 2016-01-20
HUE033005T2 (hu) 2017-11-28
JP5911859B2 (ja) 2016-04-27
US20130338394A1 (en) 2013-12-19

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Effective date: 20200813