UY32336A - Nuevos compuestos de acido 2-({ [(1Z)-1-2(2-amino-1,3-tiazol-4-il)-2-{ [(3S)-1-({ [5-hidroxi-4-oxo-1,4-dihidropiridin-2-il)-5-oxo-4-propil-4, 5 - dihidro - 1H - 1, 2, 4 - trialzol - 1 - il]sulfonil} carbamoil) -2 - oxazetidin -3 -il] amino} - 2 - oxoetiliden] amino} oxi) - 2 - metilpropanoico, composiciones farmacéuticas conteniendolos y aplicaciones. - Google Patents
Nuevos compuestos de acido 2-({ [(1Z)-1-2(2-amino-1,3-tiazol-4-il)-2-{ [(3S)-1-({ [5-hidroxi-4-oxo-1,4-dihidropiridin-2-il)-5-oxo-4-propil-4, 5 - dihidro - 1H - 1, 2, 4 - trialzol - 1 - il]sulfonil} carbamoil) -2 - oxazetidin -3 -il] amino} - 2 - oxoetiliden] amino} oxi) - 2 - metilpropanoico, composiciones farmacéuticas conteniendolos y aplicaciones.Info
- Publication number
- UY32336A UY32336A UY0001032336A UY32336A UY32336A UY 32336 A UY32336 A UY 32336A UY 0001032336 A UY0001032336 A UY 0001032336A UY 32336 A UY32336 A UY 32336A UY 32336 A UY32336 A UY 32336A
- Authority
- UY
- Uruguay
- Prior art keywords
- amino
- oxo
- pharmaceutical compositions
- trialzol
- oxazetidine
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 title 2
- -1 2-amino-1,3-thiazol-4-yl Chemical group 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 title 1
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13915908P | 2008-12-19 | 2008-12-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY32336A true UY32336A (es) | 2010-07-30 |
Family
ID=41727494
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY0001032336A UY32336A (es) | 2008-12-19 | 2009-12-17 | Nuevos compuestos de acido 2-({ [(1Z)-1-2(2-amino-1,3-tiazol-4-il)-2-{ [(3S)-1-({ [5-hidroxi-4-oxo-1,4-dihidropiridin-2-il)-5-oxo-4-propil-4, 5 - dihidro - 1H - 1, 2, 4 - trialzol - 1 - il]sulfonil} carbamoil) -2 - oxazetidin -3 -il] amino} - 2 - oxoetiliden] amino} oxi) - 2 - metilpropanoico, composiciones farmacéuticas conteniendolos y aplicaciones. |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US8252782B2 (https=) |
| EP (1) | EP2379546A1 (https=) |
| JP (1) | JP2012512863A (https=) |
| KR (1) | KR20110086742A (https=) |
| CN (1) | CN102325769A (https=) |
| AR (1) | AR074801A1 (https=) |
| AU (1) | AU2009329169B2 (https=) |
| CA (1) | CA2744756C (https=) |
| IL (1) | IL213216A0 (https=) |
| MX (1) | MX2011006541A (https=) |
| PA (1) | PA8855001A1 (https=) |
| SG (1) | SG171781A1 (https=) |
| TW (1) | TW201026696A (https=) |
| UY (1) | UY32336A (https=) |
| WO (1) | WO2010070523A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012512863A (ja) * | 2008-12-19 | 2012-06-07 | ファイザー・インク | モノカルバム |
| DK2646436T3 (en) | 2010-11-29 | 2015-06-29 | Pfizer | monobactams |
| UY34585A (es) | 2012-01-24 | 2013-09-02 | Aicuris Gmbh & Co Kg | Compuestos b-lactámicos sustituidos con amidina, su preparación y uso |
| PL3353175T3 (pl) * | 2015-09-23 | 2021-02-22 | Novartis Ag | Sole i postacie stałe antybiotyku monobaktamowego |
| CN105481812B (zh) * | 2015-11-30 | 2020-04-21 | 重庆天奕恒化科技有限公司 | 一种5-苄氧基-4-氧代-4h-吡喃-2-羧酸的制备方法 |
| AU2017339587A1 (en) | 2016-12-21 | 2019-07-04 | Aicuris Gmbh & Co. Kg | Combination therapy with amidine substituted ß-lactam compounds and ß-lactamase inhibitors for infections with antibiotic resistant bacterial strains |
| JP7235718B2 (ja) | 2017-08-02 | 2023-03-08 | ノバルティス アーゲー | モノバクタム系抗生物質およびその中間体を製造するための化学的方法 |
| CN110997627B (zh) | 2017-08-23 | 2023-10-10 | 亥姆霍兹感染研究中心有限公司 | 孢囊菌酰胺衍生物 |
| JP7366746B2 (ja) | 2017-08-31 | 2023-10-23 | 北興化学工業株式会社 | １－（ｎ，ｎ－ジ置換カルバモイル）４－（置換スルホニル）トリアゾリン－５－オン誘導体、４－（ｎ，ｎ－ジ置換カルバモイル）１－（置換スルホニル）トリアゾリン－５－オン誘導体、およびそれらを有効成分として含有する除草剤 |
| WO2019144969A1 (zh) | 2018-01-29 | 2019-08-01 | 南京明德新药研发股份有限公司 | 用于治疗细菌感染的单环β-内酰胺化合物 |
| WO2020125670A1 (zh) | 2018-12-18 | 2020-06-25 | 南京明德新药研发有限公司 | 单环β-内酰胺化合物在制药中的应用 |
| CN114828850B (zh) | 2019-12-19 | 2024-08-13 | 深圳嘉科生物科技有限公司 | 化合物在制药中的应用 |
| WO2023205463A1 (en) | 2022-04-22 | 2023-10-26 | Vertex Pharmaceuticals Incorporated | Heteroaryl compounds for the treatment of pain |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4587047A (en) * | 1981-04-09 | 1986-05-06 | E. R. Squibb & Sons, Inc. | 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines |
| NZ199981A (en) | 1981-04-09 | 1985-08-16 | Squibb & Sons Inc | 2-oxo-1-(((substituted sulphonyl)amino)carbonyl)azetidines |
| KR890700588A (ko) | 1987-02-11 | 1989-04-25 | 로버어트 에이 아미테이지 | 항생 물질로서 신규 N-1 치환된 β -락탐 |
| US5006650A (en) * | 1987-02-11 | 1991-04-09 | The Upjohn Company | Novel N-1 substituted beta-lactams as antibiotics |
| KR890700586A (ko) * | 1987-02-27 | 1989-04-25 | 로버어트 에이 아마테이지 | 피리돈 카르복실산 또는 산유도체를 함유하는 항균제 베타-락탐 |
| CA1317298C (en) * | 1987-03-03 | 1993-05-04 | Upjohn Company (The) | Antibiotic sulfonylaminocarbonyl activated .beta.-lactams |
| US4762922A (en) * | 1987-07-01 | 1988-08-09 | Squibb Corporation | 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines |
| US5015737A (en) * | 1987-07-22 | 1991-05-14 | The Upjohn Company | Therapeutically useful beta-lactams |
| US4777252A (en) * | 1987-08-13 | 1988-10-11 | E. R. Squibb & Sons, Inc. | 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines |
| US4889930A (en) | 1987-12-21 | 1989-12-26 | E. R. Squibb & Sons, Inc. | Process for making 2-oxo-1-((substituted sulfonyl)amino)carbonzyl)azetidines and intermediates used therein |
| JPH01305081A (ja) | 1988-04-04 | 1989-12-08 | E R Squibb & Sons Inc | ３―アシルアミノ―１―［［［（置換スルホニル）アミノ〕カルボニル〕アミノ〕―２―アゼチジノン類 |
| EP0344707A3 (en) | 1988-06-02 | 1990-04-18 | E.R. Squibb & Sons, Inc. | 2-Oxo-1-[[(substituted sulfonyl)-amino]carbonyl]-azetidine derivatives |
| US4959470A (en) * | 1988-08-17 | 1990-09-25 | E. R. Squibb & Sons, Inc. | 2-oxo-[[(substituted sulfonyl)-amino]carbonyl]-azetidines |
| AU4064089A (en) | 1988-09-27 | 1990-04-18 | Upjohn Company, The | Dihydroxyaryl 4-substituted monocarbams as antibiotics |
| CA2210787A1 (en) | 1997-07-17 | 1999-01-17 | William R. Collier | Self-contained work station |
| RU2488394C2 (ru) | 2007-03-23 | 2013-07-27 | Базилеа Фармацойтика Аг | Комбинированные лекарственные средства для лечения бактериальных инфекций |
| JP2012512863A (ja) * | 2008-12-19 | 2012-06-07 | ファイザー・インク | モノカルバム |
-
2009
- 2009-12-07 JP JP2011541665A patent/JP2012512863A/ja active Pending
- 2009-12-07 SG SG2011036704A patent/SG171781A1/en unknown
- 2009-12-07 KR KR1020117013944A patent/KR20110086742A/ko not_active Abandoned
- 2009-12-07 CA CA2744756A patent/CA2744756C/en not_active Expired - Fee Related
- 2009-12-07 EP EP09795553A patent/EP2379546A1/en not_active Withdrawn
- 2009-12-07 MX MX2011006541A patent/MX2011006541A/es active IP Right Grant
- 2009-12-07 AU AU2009329169A patent/AU2009329169B2/en not_active Ceased
- 2009-12-07 WO PCT/IB2009/055544 patent/WO2010070523A1/en not_active Ceased
- 2009-12-07 CN CN2009801569587A patent/CN102325769A/zh active Pending
- 2009-12-17 UY UY0001032336A patent/UY32336A/es not_active Application Discontinuation
- 2009-12-18 US US12/641,343 patent/US8252782B2/en not_active Expired - Fee Related
- 2009-12-18 TW TW098143723A patent/TW201026696A/zh unknown
- 2009-12-18 AR ARP090104977A patent/AR074801A1/es not_active Application Discontinuation
- 2009-12-18 PA PA20098855001A patent/PA8855001A1/es unknown
-
2011
- 2011-05-30 IL IL213216A patent/IL213216A0/en unknown
-
2012
- 2012-07-26 US US13/558,989 patent/US8324198B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2009329169A1 (en) | 2010-06-24 |
| WO2010070523A1 (en) | 2010-06-24 |
| IL213216A0 (en) | 2011-07-31 |
| AU2009329169B2 (en) | 2012-06-28 |
| CA2744756C (en) | 2013-05-28 |
| US8252782B2 (en) | 2012-08-28 |
| AR074801A1 (es) | 2011-02-16 |
| SG171781A1 (en) | 2011-07-28 |
| US20100160281A1 (en) | 2010-06-24 |
| CN102325769A (zh) | 2012-01-18 |
| JP2012512863A (ja) | 2012-06-07 |
| EP2379546A1 (en) | 2011-10-26 |
| US20120289455A1 (en) | 2012-11-15 |
| KR20110086742A (ko) | 2011-07-29 |
| CA2744756A1 (en) | 2010-06-24 |
| MX2011006541A (es) | 2011-07-20 |
| PA8855001A1 (es) | 2010-07-27 |
| US8324198B1 (en) | 2012-12-04 |
| TW201026696A (en) | 2010-07-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 109 | Application deemed to be withdrawn |
Effective date: 20190117 |