UY30985A1 - Procedimiento para la preparacion de derivados de epotilona por epoxidacion catalitica selectiva. - Google Patents

Procedimiento para la preparacion de derivados de epotilona por epoxidacion catalitica selectiva.

Info

Publication number
UY30985A1
UY30985A1 UY30985A UY30985A UY30985A1 UY 30985 A1 UY30985 A1 UY 30985A1 UY 30985 A UY30985 A UY 30985A UY 30985 A UY30985 A UY 30985A UY 30985 A1 UY30985 A1 UY 30985A1
Authority
UY
Uruguay
Prior art keywords
epotilone
derivatives
procedure
preparation
selective catalytic
Prior art date
Application number
UY30985A
Other languages
English (en)
Inventor
Dr Stephan Proehs
Dr Orlin Petrov
Johannes Platzek
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of UY30985A1 publication Critical patent/UY30985A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)

Abstract

La presente invencion describe un nuevo procedimiento para preparar un derivado de epotilona usando piridinas sustituidas y metiltrioxorenio como catalizador
UY30985A 2007-03-30 2008-03-27 Procedimiento para la preparacion de derivados de epotilona por epoxidacion catalitica selectiva. UY30985A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102007016046A DE102007016046A1 (de) 2007-03-30 2007-03-30 Verfahren zur Herstellung von Epothilonderivaten durch selektive katalytische Epoxidierung

Publications (1)

Publication Number Publication Date
UY30985A1 true UY30985A1 (es) 2008-10-31

Family

ID=39551678

Family Applications (1)

Application Number Title Priority Date Filing Date
UY30985A UY30985A1 (es) 2007-03-30 2008-03-27 Procedimiento para la preparacion de derivados de epotilona por epoxidacion catalitica selectiva.

Country Status (13)

Country Link
US (2) US20080242868A1 (es)
EP (1) EP2142539A2 (es)
JP (1) JP2010523481A (es)
KR (1) KR20090125259A (es)
CN (1) CN101652362B (es)
AR (1) AR066692A1 (es)
CA (1) CA2681806A1 (es)
CL (1) CL2008000901A1 (es)
DE (1) DE102007016046A1 (es)
PA (1) PA8773901A1 (es)
TW (1) TW200902538A (es)
UY (1) UY30985A1 (es)
WO (1) WO2008119563A2 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114539143A (zh) * 2022-01-28 2022-05-27 安徽瑞邦生物科技有限公司 一种4-氰基吡啶的纯化方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1140944B1 (en) * 1998-12-22 2003-08-27 Novartis AG Epothilone derivatives and their use as antitumor agents
PE20010116A1 (es) 1999-04-30 2001-02-15 Schering Ag Derivados de 6-alquenil-, 6-alquinil- y 6-epoxi-epotilona, procedimientos para su preparacion
EP1340498A1 (en) * 2002-03-01 2003-09-03 Schering Aktiengesellschaft Use of epothilones in the treatment of brain diseases associated with proliferative processes
GB0405898D0 (en) * 2004-03-16 2004-04-21 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
EP2142539A2 (de) 2010-01-13
PA8773901A1 (es) 2008-11-19
CN101652362B (zh) 2012-10-10
CA2681806A1 (en) 2008-10-09
JP2010523481A (ja) 2010-07-15
KR20090125259A (ko) 2009-12-04
US20120077984A1 (en) 2012-03-29
WO2008119563A3 (de) 2009-02-12
CL2008000901A1 (es) 2008-10-17
WO2008119563A2 (de) 2008-10-09
US8314248B2 (en) 2012-11-20
US20080242868A1 (en) 2008-10-02
TW200902538A (en) 2009-01-16
CN101652362A (zh) 2010-02-17
DE102007016046A1 (de) 2008-10-23
AR066692A1 (es) 2009-09-09

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20170919