MX2016005727A - Hidrogenacion catalitica de nitrilos. - Google Patents

Hidrogenacion catalitica de nitrilos.

Info

Publication number
MX2016005727A
MX2016005727A MX2016005727A MX2016005727A MX2016005727A MX 2016005727 A MX2016005727 A MX 2016005727A MX 2016005727 A MX2016005727 A MX 2016005727A MX 2016005727 A MX2016005727 A MX 2016005727A MX 2016005727 A MX2016005727 A MX 2016005727A
Authority
MX
Mexico
Prior art keywords
catalytic hydrogenation
nitriles
pyridin
trifluoromethyl
chloro
Prior art date
Application number
MX2016005727A
Other languages
English (en)
Other versions
MX366445B (es
Inventor
Himmler Thomas
Norbert Müller Thomas
Ahmed Moradi Wahed
Schnatterer Albert
Schlegel Günter
Original Assignee
Bayer Cropscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Ag filed Critical Bayer Cropscience Ag
Publication of MX2016005727A publication Critical patent/MX2016005727A/es
Publication of MX366445B publication Critical patent/MX366445B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/56—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
    • B01J23/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
    • B01J23/44—Palladium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57—Nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Catalysts (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a una nueva hidrogenación catalítica de derivados 2-metilcianopiridilo sustituidos, en particular, 3-cloro-5-(trifluorometil)piridin-2-il]acetonitrilo [= Py-CN) hasta derivados de 2-etilaminopiridina sustituidos, en particular, 2-[3-cloro-5-(trifluorometil)piridin-2-il]etanamina [= Py-etanamina] o sales de los mismos en presencia de catalizadores metálicos, en particular, catalizadores de paladio.
MX2016005727A 2013-11-15 2014-11-11 Hidrogenacion catalitica de nitrilos. MX366445B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13193164 2013-11-15
PCT/EP2014/074212 WO2015071230A1 (en) 2013-11-15 2014-11-11 Catalytic hydrogenation of nitriles

Publications (2)

Publication Number Publication Date
MX2016005727A true MX2016005727A (es) 2016-08-12
MX366445B MX366445B (es) 2019-07-09

Family

ID=49585315

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016005727A MX366445B (es) 2013-11-15 2014-11-11 Hidrogenacion catalitica de nitrilos.

Country Status (12)

Country Link
US (2) US9988353B2 (es)
EP (1) EP3068766B1 (es)
JP (2) JP6882891B2 (es)
KR (1) KR102314669B1 (es)
CN (1) CN105745194B (es)
BR (1) BR112016010568B1 (es)
DK (1) DK3068766T3 (es)
ES (1) ES2665579T3 (es)
IL (1) IL244947B (es)
MX (1) MX366445B (es)
TW (1) TWI650305B (es)
WO (1) WO2015071230A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2665579T3 (es) * 2013-11-15 2018-04-26 Bayer Cropscience Aktiengesellschaft Hidrogenación catalítica de nitrilos
JP7110200B2 (ja) * 2016-12-21 2022-08-01 バイエル・クロップサイエンス・アクチェンゲゼルシャフト ニトリルの接触水素化
KR102522231B1 (ko) * 2016-12-21 2023-04-14 바이엘 크롭사이언스 악티엔게젤샤프트 2-피리딜에틸카복사미드 유도체의 제조 방법
WO2020020897A1 (en) 2018-07-26 2020-01-30 Bayer Aktiengesellschaft Crystalline form of fluopyram
CN111170932A (zh) * 2020-01-13 2020-05-19 大连九信精细化工有限公司 一种2-氨甲基-5-三氟甲基吡啶盐的制备方法
CN112552231B (zh) * 2020-12-11 2022-03-11 南京正荣医药化学有限公司 一种2-(3-氯-5-(三氟甲基)吡啶-2-基)乙胺的合成方法
CN116037153A (zh) * 2023-01-03 2023-05-02 上海华谊（集团）公司 加氢脱氯催化剂及其工艺

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07138209A (ja) * 1993-11-12 1995-05-30 Sumitomo Seika Chem Co Ltd 含ハロゲンアミノメチル化合物の製造法
WO1997041846A1 (en) 1996-05-06 1997-11-13 Eli Lilly And Company Anti-viral compounds
US6645990B2 (en) * 2000-08-15 2003-11-11 Amgen Inc. Thiazolyl urea compounds and methods of uses
DE10207926A1 (de) * 2002-02-23 2003-09-11 Clariant Gmbh Verfahren zur Herstellung von primären Aminen durch Hydrierung von Nitrilen
OA19202A (en) * 2002-08-12 2006-10-13 Trinity Bay Equipment Holdings, LLC Protector assembly for flexible pipe coils and method of using same.
AU2003291227A1 (en) * 2002-11-05 2004-06-07 Smithkline Beecham Corporation Antibacterial agents
EP1674455A1 (en) 2004-12-21 2006-06-28 Bayer CropScience S.A. Process for the preparation of a 2-ethylaminopyridine derivative
KR20100016433A (ko) 2007-04-12 2010-02-12 에프. 호프만-라 로슈 아게 포스파티딜이노시톨-3-키나제의 저해제로서의 피리미딘 유도체
AU2010306750B2 (en) * 2009-10-15 2014-11-13 Children's Medical Center Corporation Sepiapterin reductase inhibitors for the treatment of pain
JP5659860B2 (ja) * 2011-02-28 2015-01-28 エヌ・イーケムキャット株式会社 ニトリル化合物水素化用パラジウム含有触媒および該触媒を用いたニトリル化合物の水素化方法
US8829238B2 (en) * 2011-09-22 2014-09-09 Ut-Battelle, Llc Methods for the synthesis of deuterated acrylate salts
GB201309340D0 (en) * 2013-05-23 2013-07-10 Led Lighting Consultants Ltd Improvements relating to power adaptors
ES2665579T3 (es) * 2013-11-15 2018-04-26 Bayer Cropscience Aktiengesellschaft Hidrogenación catalítica de nitrilos

Also Published As

Publication number Publication date
CN105745194A (zh) 2016-07-06
KR20160085778A (ko) 2016-07-18
ES2665579T3 (es) 2018-04-26
JP2019210293A (ja) 2019-12-12
US10414730B2 (en) 2019-09-17
EP3068766A1 (en) 2016-09-21
WO2015071230A1 (en) 2015-05-21
US20180244621A1 (en) 2018-08-30
JP6882891B2 (ja) 2021-06-02
CN105745194B (zh) 2018-09-25
MX366445B (es) 2019-07-09
TWI650305B (zh) 2019-02-11
DK3068766T3 (en) 2018-04-23
EP3068766B1 (en) 2018-01-10
TW201533012A (zh) 2015-09-01
JP2016538287A (ja) 2016-12-08
IL244947A0 (en) 2016-05-31
US9988353B2 (en) 2018-06-05
KR102314669B1 (ko) 2021-10-18
US20160280648A1 (en) 2016-09-29
BR112016010568A2 (pt) 2018-05-02
BR112016010568B1 (pt) 2021-09-21
IL244947B (en) 2019-03-31

Similar Documents

Publication Publication Date Title
MX366445B (es) Hidrogenacion catalitica de nitrilos.
BR302013002747S1 (pt) Configuração aplicada em metais sanitários.
SG10201903962PA (en) Method of producing an immunoligand/payload conjugate by means of a sequence-specific transpeptidase enzyme
ZA201307339B (en) Steel sheets for hot stamping,use, method of production of same, and method of production of high-strength parts.
GB201509757D0 (en) Ammonia oxidation catalyst
AP2015008922A0 (en) A process for co-production of ammonia, urea and methanol
SG11201400146RA (en) Hydrogenation and dehydrogenation catalyst, and methods of making and using the same
MX348767B (es) Metodo para preparar mentona a partir de isopulegol.
EP2920818A4 (en) SCHOTTKY DIODE ON GAN BASE WITH A PARTIALLY TAKEN DOUBLE METAL ELECTRODE
BR112013030528A2 (pt) elemento alimentador alongado, e, sistema alimentador para fundição de metal.
MX358006B (es) Catalizador de reformado de vapor y metodo para la fabricacion del mismo.
BR112015004825A2 (pt) composição microbicida aquosa.
MX362070B (es) Polioles que contienen tanino, su producción y su uso.
BR112014005761A2 (pt) complexo de catalisador de irídio, composição de catalisador, e, método de desidrogenação de alcanos
EA201400926A1 (ru) Платино-палладиевый катализатор на цеолитном носителе
CL2016001505A1 (es) Proceso para la producción de gas de síntesis de amoníaco.
MX2019007640A (es) Hidrogenacion catalitica de nitrilos.
GB201412144D0 (en) Catalyst for aldehyde production
SI2902544T1 (sl) Vodni sestavek, ki obsega polivalentno kovino, ki tvori komplekse s kabonatnimi ligandi in ligandi karboksilne kisline, ter njegova uporaba
BR112015003217A2 (pt) novos derivados de piridina.
GB201312315D0 (en) Catalyst for aldehyde production
HRP20150950T1 (en) Method for enzymatic synthesis of (7s)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carboxylic acid, and use for the synthesis of ivabradine and the salts thereof
ZA201508119B (en) Clopyralid aqueous concentrate composition
BR112014032479A2 (pt) método de preparação de derivados de 2,2- difluoroetilamina por alquilação da 2,2-difluoroetilamina.
ES1077581Y (es) Mesa para cultivo doméstico.

Legal Events

Date Code Title Description
FG Grant or registration