MX2019007640A - Hidrogenacion catalitica de nitrilos. - Google Patents

Hidrogenacion catalitica de nitrilos.

Info

Publication number
MX2019007640A
MX2019007640A MX2019007640A MX2019007640A MX2019007640A MX 2019007640 A MX2019007640 A MX 2019007640A MX 2019007640 A MX2019007640 A MX 2019007640A MX 2019007640 A MX2019007640 A MX 2019007640A MX 2019007640 A MX2019007640 A MX 2019007640A
Authority
MX
Mexico
Prior art keywords
catalytic hydrogenation
nitriles
ethanamine
pyridin
trifluoromethyl
Prior art date
Application number
MX2019007640A
Other languages
English (en)
Inventor
Himmler Thomas
Norbert Müller Thomas
Ahmed Moradi Wahed
Original Assignee
Bayer Cropscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Ag filed Critical Bayer Cropscience Ag
Publication of MX2019007640A publication Critical patent/MX2019007640A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/26—Radicals substituted by halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención se refiere a una nueva hidrogenación catalítica de derivados de 2- metilcianopiridilo sustituidos, en particular 3-cloro-5-(trifluorometil)piridin-2-il] acetonitrilo [=Py-CN] a derivados de 2-etilaminopiridina sustituidos, en particular 2-[3-cloro-5-(trifluorometil)piridin-2-il]etanamina [=Py-etanamina] o sus sales, en presencia de catalizadores Raney, en particular níquel Raney o cobalto.
MX2019007640A 2016-12-21 2017-12-18 Hidrogenacion catalitica de nitrilos. MX2019007640A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16205582 2016-12-21
PCT/EP2017/083321 WO2018114810A1 (en) 2016-12-21 2017-12-18 Catalytic hydrogenation of nitriles

Publications (1)

Publication Number Publication Date
MX2019007640A true MX2019007640A (es) 2019-09-06

Family

ID=57583030

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019007640A MX2019007640A (es) 2016-12-21 2017-12-18 Hidrogenacion catalitica de nitrilos.

Country Status (12)

Country Link
US (1) US10766859B2 (es)
EP (1) EP3558944B1 (es)
JP (1) JP7110200B2 (es)
KR (1) KR102610959B1 (es)
CN (1) CN110291069A (es)
BR (1) BR112019012885B1 (es)
DK (1) DK3558944T3 (es)
ES (1) ES2912531T3 (es)
IL (1) IL267481B (es)
MX (1) MX2019007640A (es)
TW (1) TWI762543B (es)
WO (1) WO2018114810A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112552231B (zh) * 2020-12-11 2022-03-11 南京正荣医药化学有限公司 一种2-(3-氯-5-(三氟甲基)吡啶-2-基)乙胺的合成方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE758296A (fr) 1969-11-07 1971-04-01 Rhodiatoce Procede de fabrication d'hexamethylenediamine
DE2101856C3 (de) 1971-01-15 1974-11-07 Kasachskij Gosudarstwenny Uniwersitet Imeni S.M. Kirowa, Alma-Ata (Sowjetunion) Aluminium-Nickel-Legierung, insbesondere zur Verwendung als Katalysator für die Hydrierung von ungesättigten organischen Verbindungen
DE2100373C3 (de) 1971-01-15 1979-04-12 Institut Chimitscheskich Nauk Akademii Nauk Kasachskoj Ssr Katalysator zum Hydrieren von Nitroverbindungen
US4153578A (en) 1978-07-31 1979-05-08 Gaf Corporation Catalyst comprising Raney nickel with adsorbed molybdenum compound
DE4222152A1 (de) * 1992-07-06 1994-01-13 Bayer Ag Verfahren zur Herstellung von 2-Chlor-5-aminomethyl-pyridin
PL224003B1 (pl) 2002-08-12 2016-11-30 Bayer Sas Sposób wytwarzania pochodnej 2-pirydyloetylobenzamidu
ES2350977T3 (es) 2002-11-05 2011-01-28 Glaxo Group Limited Agentes antibacterianos.
EP1500651A1 (en) 2003-07-25 2005-01-26 Bayer CropScience S.A. N-[2-(2-Pyridinyl)ethyl]benzamide compounds and their use as fungicides
EP2371814A1 (en) * 2004-10-14 2011-10-05 Abbott GmbH & Co. KG Aminoethylaromatic compounds suitable for treating disorders that respond to modulation of the dopamine D3 receptor
EP1674455A1 (en) 2004-12-21 2006-06-28 Bayer CropScience S.A. Process for the preparation of a 2-ethylaminopyridine derivative
US7915410B2 (en) * 2005-09-09 2011-03-29 Bristol-Myers Squibb Company Acyclic IKur inhibitors
TWI425917B (zh) * 2006-04-21 2014-02-11 Senomyx Inc 包含高度鮮味風味劑之可食用組合物及其製造方法
ATE496045T1 (de) 2007-04-12 2011-02-15 Hoffmann La Roche Pyrimidinderivate als inhibitoren von phosphatidylinositol-3-kinase
WO2011047156A1 (en) 2009-10-15 2011-04-21 Hercules Technology Management Co V, Inc. Sepiapterin reductase inhibitors for the treatment of pain
KR102314669B1 (ko) * 2013-11-15 2021-10-18 바이엘 크롭사이언스 악티엔게젤샤프트 니트릴의 촉매 수소화

Also Published As

Publication number Publication date
BR112019012885B1 (pt) 2022-12-27
ES2912531T3 (es) 2022-05-26
BR112019012885A2 (pt) 2019-11-26
IL267481A (en) 2019-08-29
TW201835046A (zh) 2018-10-01
KR102610959B1 (ko) 2023-12-06
KR20190092562A (ko) 2019-08-07
TWI762543B (zh) 2022-05-01
IL267481B (en) 2022-04-01
DK3558944T3 (da) 2022-05-30
US10766859B2 (en) 2020-09-08
EP3558944A1 (en) 2019-10-30
JP2020503308A (ja) 2020-01-30
EP3558944B1 (en) 2022-03-09
JP7110200B2 (ja) 2022-08-01
WO2018114810A1 (en) 2018-06-28
CN110291069A (zh) 2019-09-27
US20200039936A1 (en) 2020-02-06

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