BR112016010568A2 - hidrogenação catalítica de nitrilas - Google Patents

hidrogenação catalítica de nitrilas

Info

Publication number
BR112016010568A2
BR112016010568A2 BR112016010568A BR112016010568A BR112016010568A2 BR 112016010568 A2 BR112016010568 A2 BR 112016010568A2 BR 112016010568 A BR112016010568 A BR 112016010568A BR 112016010568 A BR112016010568 A BR 112016010568A BR 112016010568 A2 BR112016010568 A2 BR 112016010568A2
Authority
BR
Brazil
Prior art keywords
nitriles
catalytic hydrogenation
hydrogenation
catalytic
Prior art date
Application number
BR112016010568A
Other languages
English (en)
Other versions
BR112016010568B1 (pt
Inventor
Schnatterer Albert
Schlegel Günter
Himmler Thomas
Norbert Müller Thomas
Ahmed Moradi Wahed
Original Assignee
Bayer Cropscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Ag filed Critical Bayer Cropscience Ag
Publication of BR112016010568A2 publication Critical patent/BR112016010568A2/pt
Publication of BR112016010568B1 publication Critical patent/BR112016010568B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/56Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/38Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
    • B01J23/40Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
    • B01J23/44Palladium
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57Nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Catalysts (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BR112016010568-0A 2013-11-15 2014-11-11 Processo para preparação de um derivado de 2-etilaminopiridina substituída BR112016010568B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13193164 2013-11-15
EP13193164.4 2013-11-15
PCT/EP2014/074212 WO2015071230A1 (en) 2013-11-15 2014-11-11 Catalytic hydrogenation of nitriles

Publications (2)

Publication Number Publication Date
BR112016010568A2 true BR112016010568A2 (pt) 2018-05-02
BR112016010568B1 BR112016010568B1 (pt) 2021-09-21

Family

ID=49585315

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016010568-0A BR112016010568B1 (pt) 2013-11-15 2014-11-11 Processo para preparação de um derivado de 2-etilaminopiridina substituída

Country Status (12)

Country Link
US (2) US9988353B2 (pt)
EP (1) EP3068766B1 (pt)
JP (2) JP6882891B2 (pt)
KR (1) KR102314669B1 (pt)
CN (1) CN105745194B (pt)
BR (1) BR112016010568B1 (pt)
DK (1) DK3068766T3 (pt)
ES (1) ES2665579T3 (pt)
IL (1) IL244947B (pt)
MX (1) MX366445B (pt)
TW (1) TWI650305B (pt)
WO (1) WO2015071230A1 (pt)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116037153A (zh) * 2023-01-03 2023-05-02 上海华谊(集团)公司 加氢脱氯催化剂及其工艺

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015071230A1 (en) * 2013-11-15 2015-05-21 Bayer Cropscience Ag Catalytic hydrogenation of nitriles
JP7128189B2 (ja) * 2016-12-21 2022-08-30 バイエル・クロップサイエンス・アクチェンゲゼルシャフト 2-ピリジルエチルカルボキサミド誘導体を調製する方法
WO2018114810A1 (en) * 2016-12-21 2018-06-28 Bayer Cropscience Aktiengesellschaft Catalytic hydrogenation of nitriles
JP2021532138A (ja) 2018-07-26 2021-11-25 バイエル、アクチエンゲゼルシャフトBayer Aktiengesellschaft フルオピラムの結晶形
CN111170932A (zh) * 2020-01-13 2020-05-19 大连九信精细化工有限公司 一种2-氨甲基-5-三氟甲基吡啶盐的制备方法
CN112552231B (zh) * 2020-12-11 2022-03-11 南京正荣医药化学有限公司 一种2-(3-氯-5-(三氟甲基)吡啶-2-基)乙胺的合成方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07138209A (ja) * 1993-11-12 1995-05-30 Sumitomo Seika Chem Co Ltd 含ハロゲンアミノメチル化合物の製造法
EP0806205A3 (en) * 1996-05-06 1997-11-19 Eli Lilly And Company Urea, thiourea and guanidine compounds and their use as anti-viral agents
US6645990B2 (en) * 2000-08-15 2003-11-11 Amgen Inc. Thiazolyl urea compounds and methods of uses
DE10207926A1 (de) * 2002-02-23 2003-09-11 Clariant Gmbh Verfahren zur Herstellung von primären Aminen durch Hydrierung von Nitrilen
SI1531673T1 (sl) * 2002-08-12 2006-06-30 Bayer Cropscience Sa Novi 2-piridiletilbenzamidni derivati
EP1560488B1 (en) * 2002-11-05 2010-09-01 Glaxo Group Limited Antibacterial agents
EP1674455A1 (en) * 2004-12-21 2006-06-28 Bayer CropScience S.A. Process for the preparation of a 2-ethylaminopyridine derivative
MX2009010886A (es) * 2007-04-12 2009-12-14 Hoffmann La Roche Derivados de pirimidina como inhibidores de fosfatidilinositol-3-c inasa.
WO2011047156A1 (en) * 2009-10-15 2011-04-21 Hercules Technology Management Co V, Inc. Sepiapterin reductase inhibitors for the treatment of pain
JP5659860B2 (ja) * 2011-02-28 2015-01-28 エヌ・イーケムキャット株式会社 ニトリル化合物水素化用パラジウム含有触媒および該触媒を用いたニトリル化合物の水素化方法
US8829238B2 (en) * 2011-09-22 2014-09-09 Ut-Battelle, Llc Methods for the synthesis of deuterated acrylate salts
GB201309340D0 (en) * 2013-05-23 2013-07-10 Led Lighting Consultants Ltd Improvements relating to power adaptors
WO2015071230A1 (en) * 2013-11-15 2015-05-21 Bayer Cropscience Ag Catalytic hydrogenation of nitriles

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116037153A (zh) * 2023-01-03 2023-05-02 上海华谊(集团)公司 加氢脱氯催化剂及其工艺

Also Published As

Publication number Publication date
KR20160085778A (ko) 2016-07-18
MX2016005727A (es) 2016-08-12
IL244947B (en) 2019-03-31
BR112016010568B1 (pt) 2021-09-21
ES2665579T3 (es) 2018-04-26
EP3068766B1 (en) 2018-01-10
US20180244621A1 (en) 2018-08-30
WO2015071230A1 (en) 2015-05-21
IL244947A0 (en) 2016-05-31
US9988353B2 (en) 2018-06-05
KR102314669B1 (ko) 2021-10-18
CN105745194A (zh) 2016-07-06
JP6882891B2 (ja) 2021-06-02
JP2019210293A (ja) 2019-12-12
CN105745194B (zh) 2018-09-25
TW201533012A (zh) 2015-09-01
EP3068766A1 (en) 2016-09-21
US20160280648A1 (en) 2016-09-29
DK3068766T3 (en) 2018-04-23
MX366445B (es) 2019-07-09
TWI650305B (zh) 2019-02-11
JP2016538287A (ja) 2016-12-08
US10414730B2 (en) 2019-09-17

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 11/11/2014, OBSERVADAS AS CONDICOES LEGAIS.