UY27800A1 - Utilizacion de inhibidores de la transduccion de senales inducida por egfr para el tratamiento de la hiperplasia de la prostata benigna (hps) /hipertrofia de la prostata. - Google Patents

Utilizacion de inhibidores de la transduccion de senales inducida por egfr para el tratamiento de la hiperplasia de la prostata benigna (hps) /hipertrofia de la prostata.

Info

Publication number
UY27800A1
UY27800A1 UY27800A UY27800A UY27800A1 UY 27800 A1 UY27800 A1 UY 27800A1 UY 27800 A UY27800 A UY 27800A UY 27800 A UY27800 A UY 27800A UY 27800 A1 UY27800 A1 UY 27800A1
Authority
UY
Uruguay
Prior art keywords
prostate
treatment
hyperplasia
benigna
indirected
Prior art date
Application number
UY27800A
Other languages
English (en)
Inventor
Dr Thomas Singer
Dr Stefan Platz
Dr Florian Colbatzky
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of UY27800A1 publication Critical patent/UY27800A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate

Abstract

La invención se refiere a: Utilización de determinados antagonistas del receptor de EGF para preparar un medicamento para prevención y/o tratamiento de hiperplasia de próstata benigna y/o hipertrofia de próstata. Método para tratamiento o prevención de hiperplasia de próstata benigna y/o hipertrofia de prnstata que abarca la administración de un antagonista del receptor de EGF de los grupos (A) , (B) o (C) , evaentualmente en combinación con compuestos conocidos, para el tratamiento o la prevención de la hiperplasia de la próstata benigna y/o hipertrofia de la próstata, así como composiciones farmacéuticas correspondientes.
UY27800A 2002-05-11 2003-05-09 Utilizacion de inhibidores de la transduccion de senales inducida por egfr para el tratamiento de la hiperplasia de la prostata benigna (hps) /hipertrofia de la prostata. UY27800A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10221018A DE10221018A1 (de) 2002-05-11 2002-05-11 Verwendung von Hemmern der EGFR-vermittelten Signaltransduktion zur Behandlung von gutartiger Prostatahyperplasie (BPH)/Prostatahypertrophie

Publications (1)

Publication Number Publication Date
UY27800A1 true UY27800A1 (es) 2003-12-31

Family

ID=29285302

Family Applications (1)

Application Number Title Priority Date Filing Date
UY27800A UY27800A1 (es) 2002-05-11 2003-05-09 Utilizacion de inhibidores de la transduccion de senales inducida por egfr para el tratamiento de la hiperplasia de la prostata benigna (hps) /hipertrofia de la prostata.

Country Status (11)

Country Link
US (1) US8431585B2 (es)
EP (1) EP1505981B1 (es)
JP (1) JP4630659B2 (es)
AR (1) AR039987A1 (es)
AU (1) AU2003233223A1 (es)
CA (1) CA2483590C (es)
DE (1) DE10221018A1 (es)
PE (1) PE20040400A1 (es)
TW (1) TW200407147A (es)
UY (1) UY27800A1 (es)
WO (1) WO2003094921A2 (es)

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US8828391B2 (en) 2011-05-17 2014-09-09 Boehringer Ingelheim International Gmbh Method for EGFR directed combination treatment of non-small cell lung cancer
CN103254183B (zh) * 2013-05-10 2015-11-11 苏州明锐医药科技有限公司 阿法替尼的制备方法
WO2014180271A1 (zh) * 2013-05-10 2014-11-13 苏州明锐医药科技有限公司 阿法替尼及其中间体的制备方法
ES2773296T3 (es) * 2013-10-23 2020-07-10 Gemvax & Kael Co Ltd Composición para tratar y prevenir la hiperplasia prostática benigna
US9242965B2 (en) 2013-12-31 2016-01-26 Boehringer Ingelheim International Gmbh Process for the manufacture of (E)-4-N,N-dialkylamino crotonic acid in HX salt form and use thereof for synthesis of EGFR tyrosine kinase inhibitors
AU2016333987A1 (en) 2015-10-05 2018-05-10 Ny State Psychiatric Institute Activators of autophagic flux and phospholipase D and clearance of protein aggregates including tau and treatment of proteinopathies
CN105669658B (zh) * 2016-04-05 2018-06-29 北京民康百草医药科技有限公司 一种阿法替尼的精制方法
CN107488172B (zh) * 2016-06-10 2020-06-12 山东新时代药业有限公司 一种阿法替尼的制备方法

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Also Published As

Publication number Publication date
CA2483590C (en) 2011-01-04
US20100144639A1 (en) 2010-06-10
EP1505981A2 (de) 2005-02-16
WO2003094921A2 (de) 2003-11-20
JP2005526123A (ja) 2005-09-02
AR039987A1 (es) 2005-03-09
DE10221018A1 (de) 2003-11-27
EP1505981B1 (de) 2012-07-11
TW200407147A (en) 2004-05-16
WO2003094921A3 (de) 2004-03-18
AU2003233223A1 (en) 2003-11-11
JP4630659B2 (ja) 2011-02-09
US8431585B2 (en) 2013-04-30
PE20040400A1 (es) 2004-08-02
CA2483590A1 (en) 2003-11-20

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