PL2340253T3 - Sposoby selektywnego aminowania ketomorfinanów - Google Patents

Sposoby selektywnego aminowania ketomorfinanów

Info

Publication number
PL2340253T3
PL2340253T3 PL09789384T PL09789384T PL2340253T3 PL 2340253 T3 PL2340253 T3 PL 2340253T3 PL 09789384 T PL09789384 T PL 09789384T PL 09789384 T PL09789384 T PL 09789384T PL 2340253 T3 PL2340253 T3 PL 2340253T3
Authority
PL
Poland
Prior art keywords
ketomorphinans
processes
selective amination
amination
selective
Prior art date
Application number
PL09789384T
Other languages
English (en)
Inventor
Edmund C Hudson
Douglas Teramura
Christopher W Grote
Catherine E Thomasson
Gary L Cantrell
Original Assignee
SpecGx LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SpecGx LLC filed Critical SpecGx LLC
Publication of PL2340253T3 publication Critical patent/PL2340253T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/09—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems
    • C07D489/10—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14
    • C07D489/12—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14 the bridge containing only two carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL09789384T 2008-09-30 2009-09-29 Sposoby selektywnego aminowania ketomorfinanów PL2340253T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19469608P 2008-09-30 2008-09-30
EP09789384.6A EP2340253B1 (en) 2008-09-30 2009-09-29 Processes for the selective amination of ketomorphinans
PCT/US2009/005377 WO2010039222A2 (en) 2008-09-30 2009-09-29 Processes for the selective amination of ketomorphinans

Publications (1)

Publication Number Publication Date
PL2340253T3 true PL2340253T3 (pl) 2014-04-30

Family

ID=41381615

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09789384T PL2340253T3 (pl) 2008-09-30 2009-09-29 Sposoby selektywnego aminowania ketomorfinanów

Country Status (9)

Country Link
US (1) US8269006B2 (pl)
EP (1) EP2340253B1 (pl)
CN (1) CN102227434B (pl)
AU (1) AU2009300392B2 (pl)
CA (1) CA2738628C (pl)
ES (1) ES2439015T3 (pl)
NZ (2) NZ607842A (pl)
PL (1) PL2340253T3 (pl)
WO (1) WO2010039222A2 (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10221018A1 (de) * 2002-05-11 2003-11-27 Boehringer Ingelheim Pharma Verwendung von Hemmern der EGFR-vermittelten Signaltransduktion zur Behandlung von gutartiger Prostatahyperplasie (BPH)/Prostatahypertrophie
PL2398808T3 (pl) * 2009-02-17 2014-04-30 Mallinckrodt Llc Sposób redukcyjnego alkilowania normorfinanów
EP2440561B1 (en) * 2009-06-11 2014-04-30 Mallinckrodt LLC Reductive amination of 6-keto normorphinans by catalytic hydrogen transfer
CA2764915C (en) * 2009-06-11 2017-07-11 Mallinckrodt Llc Preparation of 6-alpha-amino n-substituted morphinans by catalytic hydrogen transfer
AU2011263416B2 (en) 2010-06-11 2014-04-10 Rhodes Technologies Process for N-dealkylation of tertiary amines
WO2011154827A2 (en) 2010-06-11 2011-12-15 Rhodes Technologies Transition metal-catalyzed processes for the preparation of n-allyl compounds and use thereof
PL2718294T3 (pl) 2011-06-09 2019-04-30 SpecGx LLC Redukcyjne aminowanie 6-keto morfinanów przez katalityczne przeniesienie wodoru
KR20140063763A (ko) 2011-09-08 2014-05-27 말린크로트 엘엘씨 중간체를 단리하지 않는 알칼로이드의 제조 방법
WO2015015146A1 (en) * 2013-08-02 2015-02-05 Johnson Matthey Public Limited Company Process for the preparation of oxymorphone

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CN1939920B (zh) 2005-09-29 2011-08-31 中国人民解放军军事医学科学院毒物药物研究所 东罂粟碱类化合物及其医药用途
EP2032579A2 (en) 2006-05-25 2009-03-11 Alpharma (Bermuda) Investments Ltd Process useful in the preparation of morphinan antagonists
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Also Published As

Publication number Publication date
CN102227434A (zh) 2011-10-26
US8269006B2 (en) 2012-09-18
CA2738628C (en) 2017-07-04
AU2009300392B2 (en) 2014-10-23
WO2010039222A3 (en) 2010-11-18
WO2010039222A2 (en) 2010-04-08
CA2738628A1 (en) 2010-04-08
AU2009300392A1 (en) 2010-04-08
ES2439015T3 (es) 2014-01-21
EP2340253B1 (en) 2013-11-13
CN102227434B (zh) 2015-02-18
EP2340253A2 (en) 2011-07-06
US20100081817A1 (en) 2010-04-01
NZ592005A (en) 2013-03-28
NZ607842A (en) 2013-12-20

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