CN1939920B - 东罂粟碱类化合物及其医药用途 - Google Patents
东罂粟碱类化合物及其医药用途 Download PDFInfo
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- CN1939920B CN1939920B CN2005101058284A CN200510105828A CN1939920B CN 1939920 B CN1939920 B CN 1939920B CN 2005101058284 A CN2005101058284 A CN 2005101058284A CN 200510105828 A CN200510105828 A CN 200510105828A CN 1939920 B CN1939920 B CN 1939920B
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- compound
- methyl
- formula
- oripavine
- hydroxyl
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CN2005101058284A CN1939920B (zh) | 2005-09-29 | 2005-09-29 | 东罂粟碱类化合物及其医药用途 |
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CN2005101058284A CN1939920B (zh) | 2005-09-29 | 2005-09-29 | 东罂粟碱类化合物及其医药用途 |
Publications (2)
Publication Number | Publication Date |
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CN1939920A CN1939920A (zh) | 2007-04-04 |
CN1939920B true CN1939920B (zh) | 2011-08-31 |
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CN2005101058284A Expired - Fee Related CN1939920B (zh) | 2005-09-29 | 2005-09-29 | 东罂粟碱类化合物及其医药用途 |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8530494B2 (en) | 2008-07-30 | 2013-09-10 | Purdue Pharma Lp | Buprenophine analogs |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2439015T3 (es) | 2008-09-30 | 2014-01-21 | Mallinckrodt Llc | Procedimientos de aminación selectiva de cetomorfinanos |
US8273887B2 (en) | 2008-09-30 | 2012-09-25 | Mallinckrodt Llc | Processes for synthesis of opiate alkaloid derivatives |
PL2344509T3 (pl) | 2008-09-30 | 2016-04-29 | SpecGx LLC | Sposoby wytwarzania buprenorfiny przy zmniejszonym tworzeniu zanieczyszczeń |
CN108530452B (zh) * | 2017-03-01 | 2023-02-03 | 泰州华元医药科技有限公司 | 高效抗成瘾药物 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3931189A (en) * | 1972-06-21 | 1976-01-06 | Boehringer Ingelheim Gmbh | N-(heteroaryl-methyl)-6,14-(endoethano or endoetheno)-7α-hydroxyalkyl-tetrahydro-nororipavines or-northebaines and salts thereof |
CN1408714A (zh) * | 2001-09-14 | 2003-04-09 | 中国人民解放军军事医学科学院毒物药物研究所 | 新的东罂粟碱衍生物及其医药用途 |
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2005
- 2005-09-29 CN CN2005101058284A patent/CN1939920B/zh not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3931189A (en) * | 1972-06-21 | 1976-01-06 | Boehringer Ingelheim Gmbh | N-(heteroaryl-methyl)-6,14-(endoethano or endoetheno)-7α-hydroxyalkyl-tetrahydro-nororipavines or-northebaines and salts thereof |
CN1408714A (zh) * | 2001-09-14 | 2003-04-09 | 中国人民解放军军事医学科学院毒物药物研究所 | 新的东罂粟碱衍生物及其医药用途 |
Non-Patent Citations (3)
Title |
---|
He Liu,et al,.Synthesis, crystal Structural and Pharmacological StudyofN-cyclopropylmethyl-7α-[(R)-1-hydroxyl-1-methyl-3-(thien-2-yl)propyl]-6,14-endoethanotetrahydronooripavine.Acta Chim.Slov.,80.2005,8080-85. * |
仲伯华等,.N-环丙甲基-7α-[(R)-1-羟基-1-甲基-3-(2-噻吩基)-丙基]-6,14-内乙基桥四氢去甲基蒂巴因(噻诺啡)合成和晶体结构.有机化学,25 2.2005,25(2),第210-212页. |
仲伯华等,.N-环丙甲基-7α-[(R)-1-羟基-1-甲基-3-(2-噻吩基)-丙基]-6,14-内乙基桥四氢去甲基蒂巴因(噻诺啡)合成和晶体结构.有机化学,25 2.2005,25(2),第210-212页. * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8530494B2 (en) | 2008-07-30 | 2013-09-10 | Purdue Pharma Lp | Buprenophine analogs |
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CN1939920A (zh) | 2007-04-04 |
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Inventor after: Zhong Bohua Inventor after: Gong Zehui Inventor after: Wang Jingyan Inventor after: Yu Gang Inventor after: Liu Chunhe Inventor after: Wu Bo Inventor after: Shi Weiguo Inventor after: Zhang Zhenqing Inventor after: Xie Jianwei Inventor before: Zhong Bohua Inventor before: Gong Zehui Inventor before: Wang Jingyan Inventor before: Yu Gang Inventor before: Liu Chunhe Inventor before: Wu Bo |
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Free format text: CORRECT: INVENTOR; FROM: ZHONG BOHUA GONG ZEHUI WANG JINGYAN YU GANG LIU CHUNHE WU BO TO: ZHONG BOHUA GONG ZEHUI WANG JINGYAN YU GANG LIU CHUNHE WU BO SHI WEIGUO ZHANG ZHENQING XIE JIANWEI |
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