UY27385A1 - Composición farmacéutica que comprende un inhibidor de la bomba de protones y antiácidos - Google Patents

Composición farmacéutica que comprende un inhibidor de la bomba de protones y antiácidos

Info

Publication number
UY27385A1
UY27385A1 UY27385A UY27385A UY27385A1 UY 27385 A1 UY27385 A1 UY 27385A1 UY 27385 A UY27385 A UY 27385A UY 27385 A UY27385 A UY 27385A UY 27385 A1 UY27385 A1 UY 27385A1
Authority
UY
Uruguay
Prior art keywords
protons
inhibitor
acids
pump
pharmaceutical composition
Prior art date
Application number
UY27385A
Other languages
English (en)
Inventor
Criere Bruno
Nouri Nourredine
Pilbrandt Ake
Suplie Pascal
Zuccarelli Jean-Marc
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of UY27385A1 publication Critical patent/UY27385A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/08Oxides; Hydroxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10Carbonates; Bicarbonates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Tableta de particulado múltiple desintegrable en la boca y su procedimiento de fabricación conteniendo: I) agente inhibidor de bomba de protones particularmente similar al bencimidazol, en forma de microgánulos con revestimiento entérico estando recubiertos al menos con recubrimiento actuante como barrera, por ejemplo una película a base de copolímero metacrílico; II) al menos un antiácido en forma de gránulos, por ejemplo a base de CACO3 y/o Mg (OH)2 y/o AL(OH)3 y; III) una mezcla de excipientes comprendiendo al menos un agente disgregante, un diluyente, un lubricante y opcionalmente uno para el aumento del volumen, un permeabilizante, edulcorantes, saborizantes y colorantes.-
UY27385A 2001-07-16 2002-07-16 Composición farmacéutica que comprende un inhibidor de la bomba de protones y antiácidos UY27385A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01401896 2001-07-16

Publications (1)

Publication Number Publication Date
UY27385A1 true UY27385A1 (es) 2003-02-28

Family

ID=8182807

Family Applications (1)

Application Number Title Priority Date Filing Date
UY27385A UY27385A1 (es) 2001-07-16 2002-07-16 Composición farmacéutica que comprende un inhibidor de la bomba de protones y antiácidos

Country Status (24)

Country Link
US (2) US20040219211A1 (es)
EP (1) EP1416922A1 (es)
JP (1) JP2004536855A (es)
KR (1) KR20040018463A (es)
CN (1) CN100469366C (es)
AR (1) AR034757A1 (es)
AU (1) AU2002316020B2 (es)
BG (1) BG108515A (es)
BR (1) BR0211117A (es)
CA (1) CA2453290A1 (es)
CO (1) CO5550417A2 (es)
HU (1) HUP0401941A3 (es)
IL (1) IL159584A0 (es)
IS (1) IS7111A (es)
MX (1) MXPA04000385A (es)
MY (1) MY136137A (es)
NO (1) NO20040178L (es)
NZ (1) NZ530511A (es)
PL (1) PL367686A1 (es)
RU (1) RU2301662C2 (es)
UA (1) UA75673C2 (es)
UY (1) UY27385A1 (es)
WO (1) WO2003007917A1 (es)
ZA (1) ZA200400285B (es)

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AR045068A1 (es) * 2003-07-23 2005-10-12 Univ Missouri Formulacion de liberacion inmediata de composiciones farmaceuticas
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JP3841804B2 (ja) * 2003-10-15 2006-11-08 富士化学工業株式会社 口腔内速崩壊性錠剤用の組成物
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EP1621187A1 (en) * 2004-07-26 2006-02-01 AstraZeneca AB Pharmaceutical multiparticulate tablet formulations and process for their preparation
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DE102005024614A1 (de) * 2005-05-25 2006-11-30 Röhm Gmbh Verwendung von Polymermischungen zur Herstellung von überzogenen Arzneiformen sowie Arzneiform mit polymerem Mischüberzug
US20080166407A1 (en) * 2005-07-29 2008-07-10 Shalaby Shalaby W Solid oral formulations for combination therapy
CN100431526C (zh) * 2005-11-07 2008-11-12 上海艾力斯医药科技有限公司 一种酸敏感型药物的快速崩解片剂
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WO2009086942A1 (en) * 2008-01-10 2009-07-16 Evonik Röhm Gmbh Coated pharmaceutical or nutraceutical preparation with accelerated controlled active substance release
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RU2497503C9 (ru) * 2008-03-10 2014-09-20 Байер Конзюмер Кер АГ Приятная на вкус твердая композиция, включающая нейтрализатор кислотности и стимулятор слюноотделения
GEP20135845B (en) 2008-03-11 2013-06-10 Takeda Pharmaceutical Orally-disintegrating solid formulation
MX2011004744A (es) * 2008-11-17 2011-05-30 Nycomed Pharma As Estabilidad mejorada de disolucion de tabletas de carbonato de calcio.
KR101908748B1 (ko) * 2010-12-03 2018-10-16 다케다 야쿠힌 고교 가부시키가이샤 구강내 붕괴정
CN102085188B (zh) * 2011-01-14 2013-01-02 寿光富康制药有限公司 一种兰索拉唑肠溶微丸的制备方法
CN102078616A (zh) * 2011-01-28 2011-06-01 北京虹湾医药技术有限公司 埃索美拉唑碳酸氢钠组合物
US8277842B1 (en) * 2012-01-20 2012-10-02 Dart Neuroscience (Cayman) Ltd. Enteric-coated HT-2157 compositions and methods of their use
CN102631327B (zh) * 2012-05-14 2013-08-28 海南葫芦娃制药有限公司 一种奥美拉唑肠溶微丸及其制备方法
CN103479593B (zh) * 2013-05-10 2014-10-08 青岛双鲸药业有限公司 一种奥美拉唑肠溶片的制备方法
JP6156037B2 (ja) * 2013-10-03 2017-07-05 ライオン株式会社 固形医薬製剤組成物
CN103784414B (zh) * 2013-12-18 2018-01-30 北京华禧联合科技发展有限公司 一种埃索美拉唑肠溶片及其制备方法
CA2910865C (en) 2014-07-15 2016-11-29 Isa Odidi Compositions and methods for reducing overdose
EP3288556A4 (en) 2015-04-29 2018-09-19 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
CA3010778C (en) * 2016-02-03 2024-02-27 Novartis Ag Galenic formulations of organic compounds
US20190151297A1 (en) * 2016-04-29 2019-05-23 Nauts Equine Brand Pty Ltd Veterinary Composition
US10076494B2 (en) * 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
CN108434117A (zh) * 2018-03-29 2018-08-24 成都通德药业有限公司 一种奥美拉唑肠溶胶囊的制备方法
RU2727506C1 (ru) * 2019-09-09 2020-07-22 Пивипи Лабс Пте. Лтд. Средство для лечения эректильной дисфункции
CN114980867B (zh) * 2020-01-23 2024-03-15 韩美药品株式会社 包含质子泵抑制剂和抗酸剂的药物复合制剂
KR20220065997A (ko) * 2020-11-13 2022-05-23 (주)휴온스 라베프라졸 및 제산제를 포함하는 약제학적 복합제제 및 이의 제조방법
CN116887866A (zh) 2020-12-03 2023-10-13 巴特尔纪念研究院 聚合物纳米颗粒和dna纳米结构组合物及用于非病毒递送的方法
CN114617852B (zh) * 2020-12-10 2023-06-27 昆药集团股份有限公司 一种奥美拉唑肠溶制剂及其制备方法
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Also Published As

Publication number Publication date
MY136137A (en) 2008-08-29
ZA200400285B (en) 2005-06-29
UA75673C2 (en) 2006-05-15
WO2003007917A1 (en) 2003-01-30
CN100469366C (zh) 2009-03-18
PL367686A1 (en) 2005-03-07
KR20040018463A (ko) 2004-03-03
AU2002316020B2 (en) 2007-03-15
BR0211117A (pt) 2004-06-22
CA2453290A1 (en) 2003-01-30
RU2004101061A (ru) 2005-04-20
NO20040178L (no) 2004-03-16
HUP0401941A3 (en) 2008-04-28
IL159584A0 (en) 2004-06-01
CN1555256A (zh) 2004-12-15
HUP0401941A2 (hu) 2005-01-28
CO5550417A2 (es) 2005-08-31
RU2301662C2 (ru) 2007-06-27
EP1416922A1 (en) 2004-05-12
US20110135722A1 (en) 2011-06-09
IS7111A (is) 2004-01-15
NZ530511A (en) 2005-06-24
AR034757A1 (es) 2004-03-17
BG108515A (en) 2005-02-28
US20040219211A1 (en) 2004-11-04
JP2004536855A (ja) 2004-12-09
MXPA04000385A (es) 2004-05-04

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