US9995618B2 - Capsule-weighing device, capsule-filling machine, and method for weighing a capsule - Google Patents

Capsule-weighing device, capsule-filling machine, and method for weighing a capsule Download PDF

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Publication number
US9995618B2
US9995618B2 US14/414,133 US201314414133A US9995618B2 US 9995618 B2 US9995618 B2 US 9995618B2 US 201314414133 A US201314414133 A US 201314414133A US 9995618 B2 US9995618 B2 US 9995618B2
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Prior art keywords
capsule
weighing
holder
capsule holder
weighing device
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US14/414,133
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US20150204714A1 (en
Inventor
Walter Boehringer
Jens Schlipf
Martin Vogt
Thomas Franck
Werner Runft
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Syntegon Technology GmbH
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Robert Bosch GmbH
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Assigned to ROBERT BOSCH GMBH reassignment ROBERT BOSCH GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: BOEHRINGER, WALTER, FRANCK, THOMAS, RUNFT, WERNER, SCHLIPF, JENS, VOGT, MARTIN
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Assigned to ROBERT BOSCH PACKAGING TECHNOLOGY GMBH reassignment ROBERT BOSCH PACKAGING TECHNOLOGY GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: ROBERT BOSCH GMBH
Assigned to SYNTEGON TECHNOLOGY GMBH reassignment SYNTEGON TECHNOLOGY GMBH CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: ROBERT BOSCH PACKAGING TECHNOLOGY GMBH
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01GWEIGHING
    • G01G17/00Apparatus for or methods of weighing material of special form or property
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/074Filling capsules; Related operations
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B1/00Packaging fluent solid material, e.g. powders, granular or loose fibrous material, loose masses of small articles, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B1/04Methods of, or means for, filling the material into the containers or receptacles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B7/00Closing containers or receptacles after filling
    • B65B7/16Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons
    • B65B7/28Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons by applying separate preformed closures, e.g. lids, covers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01GWEIGHING
    • G01G7/00Weighing apparatus wherein the balancing is effected by magnetic, electromagnetic, or electrostatic action, or by means not provided for in the preceding groups
    • G01G7/06Weighing apparatus wherein the balancing is effected by magnetic, electromagnetic, or electrostatic action, or by means not provided for in the preceding groups by electrostatic action
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2200/00General characteristics or adaptations
    • A61J2200/70Device provided with specific sensor or indicating means
    • A61J2200/74Device provided with specific sensor or indicating means for weight

Definitions

  • the present invention relates to a capsule-weighing device, and to a capsule-filling machine comprising the capsule-weighing device.
  • a method for weighing a capsule is also disclosed.
  • the capsule is filled in particular with medical preparations.
  • the capsule-weighing device With the capsule-weighing device according to the invention, the capsule-filling machine and the method, it is possible that each capsule lower part inserted into the capsule holder is weighed individually, without the capsule lower part moving relative to the capsule holder.
  • the weighing unit is separate from the transport unit and the capsule holder, such that the structure is simple and requires only low maintenance. It is a stationary weighing unit, or a weighing unit that can be moved and positioned independently of the capsule holder. Thus, ideally, only one weighing unit is needed for an entire capsule-filling machine. This one weighing unit can be used at various locations on the capsule-filling machine.
  • the capsule lower part remains securely and free of movement in the capsule holder.
  • the capsule lower part does not have to be removed from and placed back into the capsule holder, and therefore a potential source of error is eliminated.
  • the net weight of each filled capsule lower part can be determined individually.
  • the arrangement according to the invention permits individual weighing of each empty capsule lower part and also of each capsule lower part after partial or complete filling.
  • the medium introduced into the capsule is not measured before the filling procedure. According to the invention, the medium is weighed after the filling procedure, i.e. in the capsule lower part.
  • the weighing unit is separate from the capsule holder and, on the other hand, the capsule lower parts are received in the capsule holder in such a way that an outer wall of the capsule lower parts is either partially exposed or is enclosed by only a very thin wall of the capsule holder.
  • the weighing device is provided with at least one electrode per capsule lower part to be measured.
  • the capsule-weighing device comprises a capsule holder for receiving at least one capsule lower part.
  • the capsule holder is designed to receive a multiplicity of capsule lower parts, in particular more than three capsule lower parts.
  • a weighing unit with at least a first electrode is provided for weighing the capsule lower parts on the capsule holder.
  • one first electrode is provided per capsule lower part.
  • the capsule holder can be moved, independently of the weighing unit, to various stations, for example an insert station, a filling station and a closing station.
  • a second electrode is needed as a counterpart to the first electrode. As is explained later in more detail, this second electrode is formed either on the capsule holder or on the weighing unit.
  • the seat in the capsule holder for the individual capsule lower parts is so configured that the outer wall of each capsule lower part is either exposed or is enclosed by only a very thin wall of the material of the capsule holder. It is thereby possible for a first electrode to come very close to each capsule lower part. An exact measurement is thus made possible. The measurement by means of the electric field takes place particularly by using the two electrodes as capacitor or by what is called the relaxation measurement. Both methods are described in DE 2008 037 986 A1.
  • the capsule holder comprises, for each capsule lower part to be received, a dedicated thin-walled pot.
  • the pot has, at the lower end and/or on its circumferential surface, at least one aperture. The design of these pots permits a very exact movement of the weighing unit to the capsule lower parts.
  • the material thickness of the capsule holder between electrode and capsule lower part i.e. in particular the material thickness of the abovementioned pots, is at most 3 mm, preferably at most 1.5 mm, particularly preferably at most 0.5 mm.
  • the capsule holder is preferably designed such that at least the areas responsible for receiving the capsule are made from materials which permit good capacitive measurement or the like. That is to say, at least the portions of the capsule holder that touch the capsule lower part are electrically non-conductive, preferably made of plastic.
  • both the first electrode and also the second electrode are located on the weighing unit.
  • One first electrode and one second electrode are provided for each capsule lower part that is to be weighed.
  • the weighing unit is driven to the capsule holder in such a way that a capsule lower part is in each case located between a first electrode and a second electrode.
  • the second electrode is formed in the capsule holder. In this case, when the weighing unit is driven to the capsule holder, only the first electrode has to be brought into contact with the pot or directly with the capsule part.
  • a sealed space arises when the weighing unit is placed onto the capsule holder. At least the contact point between the first electrode and the pot or the capsule lower part is located in this sealed space.
  • a vacuum pump By means of a vacuum pump, an underpressure is generated in the sealed space. A very exact measurement is thus made possible.
  • the vacuum is applied to ensure that the capsule bears securely with a defined force on the electrode. This force can be generated by the vacuum. Alternatively, however, this force can be generated by using compressed air from above or by some other means, e.g. by a spring or the like.
  • the invention further comprises a capsule-filling machine.
  • the advantageous embodiments described in the context of the capsule-weighing device according to the invention are accordingly applied advantageously to the capsule-filling machine according to the invention.
  • the capsule-filling machine comprises at least one of the capsule-weighing devices.
  • the capsule-filling machine comprises an insert station for inserting the capsule lower parts into the capsule holder.
  • a filling station serves for filling the capsule lower part.
  • a capsule upper part is placed onto the capsule lower part.
  • the empty capsule lower part has to be weighed before the first filling.
  • the capsule lower part has to be weighed in order to check whether the desired amount of the individual preparation is in the capsule lower part. Therefore, the weighing unit can be driven to the capsule holder at the individual stations and/or between the stations. Alternatively, the capsule holder can also be driven to the weighing unit. During weighing, there is no movement of the capsule lower parts in the capsule holder.
  • the weighing unit can be installed one or more stations before the filling station in order to determine the tare weight, and/or one or more stations later in order to determine the gross weight. If the weighing unit is used directly under a filling station, the tare weight can be measured first, after which the filling takes place and, subsequently, the measurement of the gross weight, such that the net weight can be determined, or the weighing unit is set to “0” on taring, such that the filling weight can be determined directly after filling.
  • the invention further comprises a method for weighing a capsule.
  • the advantageous embodiments described in the context of the capsule-weighing device and capsule-filling machine are accordingly applied advantageously to the method according to the invention.
  • a capsule holder with at least one inserted capsule lower part is made available.
  • several capsule lower parts are inserted.
  • the capsule lower part remains in the capsule holder during filling, transporting and closing.
  • a weighing unit is driven to the capsule holder and/or the capsule holder is driven to the weighing unit for weighing the at least one capsule lower part with an electric field.
  • the capsule lower part remains motionless in the capsule holder.
  • the capsule holder is designed, for the capsule-weighing device, for the capsule-filling machine and for the method according to the invention, such that two or more capsule lower parts can be received therein.
  • the weighing unit is designed such that at least two of the capsule lower parts, preferably all of the capsule lower parts, can be weighed at the same time.
  • FIG. 1 shows a first sectional view of a capsule-weighing device according to the invention in a first illustrative embodiment
  • FIG. 2 shows a second sectional view of the capsule-weighing device according to the invention in the first illustrative embodiment
  • FIG. 3 shows an isometric view of the capsule-weighing device according to the invention in the first illustrative embodiment
  • FIG. 4 shows a detail of the capsule-weighing device according to the invention in a second illustrative embodiment
  • FIG. 5 shows a first sectional view of the capsule-weighing device according to the invention in a third illustrative embodiment
  • FIG. 6 shows a second sectional view of the capsule-weighing device according to the invention in the third illustrative embodiment
  • FIG. 7 shows a capsule-filling machine according to the invention in a fourth illustrative embodiment
  • FIG. 8A shows an isometric view from below of a capsule holder for the capsule-weighing device according to the invention in a fifth illustrative embodiment
  • FIG. 8B is a plan view of the capsule holder shown in FIG. 8A .
  • FIG. 8C is a view taken along line B-B in FIG. 8B .
  • FIG. 9A shows an isometric view from below of a capsule holder for the capsule-weighing device according to the invention in a sixth illustrative embodiment
  • FIG. 9B is a sectional view of the capsule holder shown in FIG. 9A .
  • a first illustrative embodiment of a capsule-weighing device 1 is described below with reference to FIGS. 1 to 3 .
  • the capsule-weighing device 1 comprises a capsule holder 2 which, by means of a transport device 3 , can be moved to various stations S 1 to S 12 (see FIG. 7 ) of a capsule-filling machine 16 (see FIG. 7 ).
  • the capsule holder 2 has a plurality of pots 11 . Capsule lower parts 4 are inserted into these pots 11 .
  • the capsule lower parts 4 are filled in particular with medical preparations and closed.
  • a further component part of the capsule-weighing device 1 is a weighing unit 5 , which can be moved and positioned independently of the capsule holder 2 .
  • the weighing unit 5 comprises a first electrode 8 and a second electrode 9 per capsule lower part 4 and per pot 11 .
  • FIG. 1 shows the capsule-weighing device 1 at a filling device 6 of a filling station S 5 to S 7 (see FIG. 7 ).
  • the weighing unit 5 is located in a position in which weighing of the capsule lower parts 4 is possible.
  • the weighing unit 5 is located in a position before and after weighing.
  • FIG. 2 indicates the corresponding feed movement 10 that is needed in order to drive the electrodes 8 , 9 directly to the pots 11 or the capsule lower parts 4 .
  • the capsule lower parts 4 each have an outer wall 7 . With this outer wall 7 , the capsule lower parts 4 are received with a form fit and/or force fit in the capsule holder 2 , in particular in the pots 11 .
  • the pots 11 are designed such that the outer wall 7 is partially exposed and/or is enclosed only by extremely thin material of the pots 11 .
  • a suitably small material thickness 13 of the pots 11 is shown in FIG. 4 .
  • FIG. 3 shows an isometric view of the capsule-weighing device 1 according to the first illustrative embodiment. It shows that pots 11 are provided in a capsule holder 2 . A capsule lower part 4 sits in each of the pots 11 . By means of the weighing unit 5 , each capsule lower part 4 can be separately weighed simultaneously.
  • FIG. 4 shows in detail a second illustrative embodiment of the capsule-weighing device 1 .
  • the pots 11 have several apertures 12 both at the lower end and also on the circumferential surface. Through these apertures 12 , the capsule lower parts 4 can be still better measured by means of the electric field between the two electrodes 8 , 9 .
  • FIGS. 5 and 6 show a third illustrative embodiment of the capsule-weighing device 1 .
  • the weighing unit 5 is located in a position for measuring the capsule lower parts 4 .
  • the weighing unit 5 is located in a position before or after weighing.
  • the second electrode 9 is formed in the capsule holder 2 .
  • the weighing unit 5 comprises only first electrodes 8 .
  • the weighing unit 5 is provided with one first electrode 8 per capsule lower part 4 or per pot 11 .
  • the lower ends of the capsule lower parts 4 lie exposed in the pots 11 or in the capsule holder 2 .
  • the weighing unit 5 is driven upward, such that in each case a first electrode 8 is driven to a lower end of the capsule lower parts 4 .
  • the weighing unit 5 comprises a sealing lip 15 .
  • a sealed space 14 is closed between capsule holder 2 and weighing unit 5 .
  • the contact point between capsule lower parts 4 and first electrodes 8 is located in this sealed space 14 .
  • a vacuum pump not shown
  • underpressure can be generated in the sealed space 14 and, in this way, the measuring accuracy can be increased.
  • FIG. 7 shows a capsule-filling machine 16 according to a fourth illustrative embodiment, comprising one of the capsule-weighing devices 1 described above. Structural parts that are identical or have an identical function are provided with the same reference signs in all of the embodiments.
  • FIG. 7 shows that, in the capsule-filling machine 16 , the capsules are moved in a circle by means of the transport device 3 .
  • the capsule upper parts 18 are transported in the holder 17 shown, while the capsule lower parts 4 are being filled.
  • Stations S 1 to S 12 are passed through.
  • the capsules are inserted into the capsule holder 2 .
  • the capsules are weighed (tare) and a capsule upper part 18 is removed from the capsule lower part 4 .
  • the capsule lower parts 4 are filled.
  • the capsule upper part 18 is placed onto the capsule lower part 4 .
  • the completely filled capsules are weighed.
  • defective capsules are rejected.
  • capsules are removed from the capsule holder 2 .
  • the capsule holder 2 is cleaned.
  • the weighing of the capsules is represented by a symbolic balance.
  • the weighing of the capsule lower part 4 with the capsule-weighing device 1 according to the invention is carried out at various locations in the capsule-filling machine 16 , for example at the individual stations S 1 to S 12 or between the stations.
  • the capsule upper part 18 can also be placed on the capsule lower part 4 during this weighing procedure.
  • FIG. 8 shows two variants of the design of the capsule holder 2 .
  • FIG. 8 shows an isometric view of the capsule holder 2 from below.
  • a plan view and a sectional view are shown on the right-hand side.
  • FIG. 8 shows two different variants of the design of the capsule holder 2 .
  • the area 21 indicates a first variant.
  • the area 22 indicates a second variant.
  • different webs 23 are used to stiffen the pots 11 .
  • different webs 23 can be formed both transversely and also longitudinally between the pots 11 in order to stiffen the latter.
  • the webs 23 are arranged such that one of the above-described weighing units 5 can always be moved with the corresponding electrodes 8 , 9 as close as possible to the pots 11 .
  • FIG. 9 shows the design of the capsule holder 2 according to a sixth illustrative embodiment.
  • An isometric view of the capsule holder 2 is shown in the upper area of FIG. 9 .
  • a sectional view is shown in the lower area.
  • the pots 11 can also extend upward on the capsule holder 2 . Accordingly, the weighing unit 5 is driven to the pots 11 from above and/or from the side.

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  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Electromagnetism (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Basic Packing Technique (AREA)
US14/414,133 2012-07-10 2013-05-15 Capsule-weighing device, capsule-filling machine, and method for weighing a capsule Active 2034-10-20 US9995618B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE102012212033 2012-07-10
DE102012212033.5A DE102012212033A1 (de) 2012-07-10 2012-07-10 Kapselwägevorrichtung, Kapselfüllmaschine und Verfahren zum Wiegen einer Kapsel
DE102012212033.5 2012-07-10
PCT/EP2013/059983 WO2014009040A1 (de) 2012-07-10 2013-05-15 Kapselwägevorrichtung, kapselfüllmaschine und verfahren zum wiegen einer kapsel

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US20150204714A1 US20150204714A1 (en) 2015-07-23
US9995618B2 true US9995618B2 (en) 2018-06-12

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US (1) US9995618B2 (de)
EP (1) EP2872102B1 (de)
CN (1) CN104507442B (de)
DE (1) DE102012212033A1 (de)
ES (1) ES2575504T3 (de)
WO (1) WO2014009040A1 (de)

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US11307079B2 (en) * 2018-01-04 2022-04-19 Syntegon Technology Gmbh Device for determining the weight of a capsule arranged in a capsule holder of an incrementally rotated conveyor wheel
US11376196B2 (en) 2017-10-31 2022-07-05 I.M.A. Industria Macchine Automatiche S.P.A. Filling machine

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EP3224146B1 (de) * 2014-11-26 2019-10-16 Azionaria Costruzioni Macchine Automatiche A.C.M.A. S.p.A. Kapselherstellungsmaschine
ITUA20163077A1 (it) * 2016-05-02 2017-11-02 Mg 2 Srl Gruppo di alimentazione per il dosaggio di granuli, in particolare microgranuli, in capsule
DE102016218085A1 (de) 2016-09-21 2018-03-22 Robert Bosch Gmbh Wirbelschichtanlage
GB201620628D0 (en) * 2016-12-05 2017-01-18 3P Innovation Ltd Capsule Filler
DE102017207307A1 (de) 2017-03-13 2018-09-13 Bausch + Ströbel Maschinenfabrik Ilshofen GmbH + Co. KG System mit alternierender Füllung von Behältern und Verfahren hierzu
IT201700086434A1 (it) * 2017-07-27 2019-01-27 Mg 2 Srl Dispositivo di misura per una macchina opercolatrice di capsule farmaceutiche
CN107719721A (zh) * 2017-09-29 2018-02-23 南昌富泰力诺检测应用系统有限公司 微量固体粉末自动定量分装压盖系统
EP3488841B1 (de) * 2017-11-24 2020-03-18 Harro Höfliger Verpackungsmaschinen GmbH Kapselwiegeeinrichtung und kapselfülleinrichtung mit einer solchen kapselwiegeeinrichtung
WO2019149345A1 (de) 2018-01-31 2019-08-08 Robert Bosch Gmbh Vorrichtung zum dosieren eines produkts
DK3545937T3 (da) * 2018-03-28 2022-08-15 Hoefliger Harro Verpackung Kapselbøsning til stikkapsler og bøsningssystem
US11366004B2 (en) 2018-07-18 2022-06-21 Mg 2—S.R.L. Electronic device for detecting the weight of capsules for pharmaceutical products
EP3607931B1 (de) * 2018-08-07 2023-03-29 Harro Höfliger Verpackungsmaschinen GmbH Kapselverschliesseinrichtung zum verschliessen zweiteiliger kapseln
IT201900007266A1 (it) * 2019-05-27 2020-11-27 Ima Spa Apparecchiatura e procedimento di pesatura, preferibilmente per pesare uno o piu’ contenitori configurati per contenere prodotti fluidi, solidi o in polvere, in una macchina di riempimento automatico dei suddetti contenitori.
DE102019135276A1 (de) * 2019-12-19 2021-06-24 James Bradley Vorrichtung zur Messung des Füllinhalts flüssigkeitsgefüllter Behältnisse

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US20150204714A1 (en) 2015-07-23
EP2872102B1 (de) 2016-04-20
DE102012212033A1 (de) 2014-01-16
CN104507442A (zh) 2015-04-08
EP2872102A1 (de) 2015-05-20
CN104507442B (zh) 2018-06-08
WO2014009040A1 (de) 2014-01-16

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