US20060153693A1 - Administering apparatus comprising a service life timer - Google Patents
Administering apparatus comprising a service life timer Download PDFInfo
- Publication number
- US20060153693A1 US20060153693A1 US11/316,208 US31620805A US2006153693A1 US 20060153693 A1 US20060153693 A1 US 20060153693A1 US 31620805 A US31620805 A US 31620805A US 2006153693 A1 US2006153693 A1 US 2006153693A1
- Authority
- US
- United States
- Prior art keywords
- adder
- movement
- recorder
- input member
- coupler
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3202—Devices for protection of the needle before use, e.g. caps
- A61M5/3204—Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
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- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31553—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe without axial movement of dose setting member
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- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/31555—Mechanically operated dose setting member by purely axial movement of dose setting member, e.g. during setting or filling of a syringe
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- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
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- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
- A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B49/00—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00
- F04B49/10—Other safety measures
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- A61M2005/2006—Having specific accessories
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- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
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- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
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- A61M5/178—Syringes
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- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
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- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
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Definitions
- the invention relates to medical devices and methods of using and making such devices. More particularly, it relates to an administering apparatus for administering a fluid product. It is preferably used in an injection apparatus in the form of an injection pen. Injection apparatus and/or infusion apparatus may be used for diabetes therapy, administering growth hormones or osteoporosis preparations. In particular, in cases in which a user self-administers a product or substance, the user has to be able to rely on his/her apparatus operating reliably. In principle, however, this requirement also applies in the out-patient, clinical and veterinary fields, which also represent areas of application for the invention.
- WO 03/057285 A2 is an example of an injection apparatus that includes a weekday display which is adjusted when setting the dosage. According to this example, when a dosage is to be administered daily, a user may check that he/she has administered the intended dosage.
- the present invention comprises an administering apparatus, such as an injection apparatus or an infusion apparatus, having a service life timer.
- the administering apparatus includes a casing with a reservoir for a container for a product to be administered, a conveying member for the product, an adder for recording and adding a change in the state of the apparatus, and an output coupled to the adder providing a perceptible signal in response to a change in state of the apparatus.
- the present invention comprises an administering apparatus, such as an injection apparatus or an infusion apparatus, comprising a service life timer, the administering apparatus comprising a casing comprising a reservoir for a container for a product to be administered, a conveying member for the product, an adder for recording and adding a change in the state of the apparatus, wherein the adder is incremented upon administering the product, and an output means coupled to the adder, the output means outputting a signal perceivable by the senses, in accordance with the addition result.
- an administering apparatus such as an injection apparatus or an infusion apparatus, comprising a service life timer
- the administering apparatus comprising a casing comprising a reservoir for a container for a product to be administered, a conveying member for the product, an adder for recording and adding a change in the state of the apparatus, wherein the adder is incremented upon administering the product, and an output means coupled to the adder, the output means outputting a signal perceivable by the sense
- the apparatus is equipped with a service life timer which provides the user with an indication of when the apparatus has reached its service life, after which it is no longer certain that the apparatus will function reliably.
- the service life timer includes an adder, preferably a mechanical adder (although any suitable combinational component, whether mechanical, electrical, analog or digital, may be used), for recording and adding a change in the state of the apparatus which results from repeated administration of the product. In this way, changes to the state of the apparatus due to normal wear and tear are tracked. Such changes in state occur when setting a product dosage to be administered and when delivering said dosage. Over the total period of use of the apparatus, these changes in state are constantly repeated, often several times per day, and accumulatively lead to a gradual loss of reliability.
- the service life timer also includes an output means which is connected to the adder and outputs a signal which can be perceived by the senses, in accordance with the addition result.
- the display may include an acoustic, tactile, and/or optical display.
- the service life timer operates without electrical energy.
- the adder counts the number of container changes.
- the number of container changes may be regarded as an integral value for the number of deliveries and/or dosage setting processes if the apparatus is equipped with a dosing means. If the number of container changes has reached or exceeded a predetermined critical value, the output means may indicate to the user that the apparatus has reached the end of its service life.
- the apparatus may also be equipped with a blocking (or locking) means which is coupled to the service life timer such that when the end of the service life is reached, the service life timer automatically places the blocking means in a blocking state preventing product delivery.
- a blocking means preferably operates after a warning indication is signaled by the output means. This allows sufficient time for the user to acquire a new apparatus.
- the adder only counts the number of container changes as changes in state.
- the apparatus may additionally count the number of deliveries and/or dosage setting processes and incorporate these in ascertaining the end of the service life.
- the adder may count the number of deliveries, the number of dosage setting processes, or may counts these two changes in state in combination.
- Each type of action may be weighted according to the extent it wears on the apparatus. For example, delivery movements may wear more on the apparatus compared to the dosage setting process. When the adder increments for delivery, the increment may be larger compared to the increment corresponding to the dosage setting.
- the output means in addition to indicating that an “end of service life” event has occurred, the output means may also indicate the approaching expiration of the service life of the apparatus. For example, ten or twenty container changes before the expiration of the apparatus, the output means may sound a warning signal indicating the apparatus' status.
- the output means may also include an output structure for an optical display.
- the expiration of service life indication may be imparted by a colored marking. For example, a color which is characteristic of the non-critical range, for example green, may be displayed up until a critical service life is reached, and then a warning color such as red may be displayed.
- the colored marking may also include one or more transition regions, for example from green to red. The transition regions may be yellow, or yellow and orange in succession.
- the output structure may thus be provided with a colored strip which is colored continuously green in a first portion and then abruptly red, may be colored yellow in an adjoining second strip and then transition to red, or may be colored yellow, then orange, and then red. Accordingly, a colored strip may be used which continuously changes in color, or color graduations may form the optical display.
- an illuminated display such as a rear illumination may also be provided. The illuminated display may also be equipped with an energy source of its own and thus autonomous from the apparatus.
- the adder cooperates with an actuator which is actuated in response to the change in device status or device state.
- an actuator may be formed by an operable triggering element which performs a triggering movement which causes a delivery movement of the conveying member.
- the conveying member also forms a preferred actuator, either as an alternative to the triggering element, or in a coupling with the triggering element which is established directly by the change in device status, or only when the change in device status is recorded. Both the coupling with the triggering element and the coupling with the conveying member enable the delivery processes to be counted.
- a dosing member of the dosing means may form the actuator.
- the dosing movement of the dosing member is recorded.
- the triggering element also simultaneously forms a dosing member which is moved when setting the dosage
- the dosing movement of the triggering element may be recorded instead of or in addition to the triggering movement.
- the adder for recording and adding the change in device status is coupled both to the triggering element and the conveying member.
- the conveying member or the triggering element can mount to the adder.
- This type of coupling is particularly suitable for counting the container changes if, after a new filled container is inserted, the conveying member assumes a different position relative to the triggering element than after the container is emptied or partially emptied.
- Mounting the adder using the triggering element is particularly preferably combined with recording the change in state on the basis of a position which the conveying member assumes relative to the triggering element.
- container changes may also be determined solely on the basis of recording the position of the conveying member relative to the casing of the apparatus or to another structure.
- the adder may be coupled to casing parts of the casing such that the separating or connecting processes of the casing parts, to be performed for a container change, are recorded. While the number of separating and connecting processes does not have to exactly match the number of container changes, the number of separating and connecting processes may provide a useful indication.
- the adder may be formed by a mechanical reducing gear.
- the reducing gear may operate pneumatically, hydraulically, or may operate by pneumatic and hydraulic components.
- a recorder for the individual changes in device status may form the input or trigger the drive member of the reducing gear.
- the recorder may thus be a movement recorder, or a contact recorder, which is itself moved by contact with the actuator cited.
- the movements of such a recorder caused by the changes in device status are reduced by other gear components and transferred to the output means, for example onto a display structure.
- the recorder may be coupled to a subsequent adding member, such that the changes in device status cause a movement of the adding member. If the recorder is moved by the change in device status, its movements are preferably mechanically transferred onto the adding member. In each case, the adding member is moved on from an initial position, which it assumes before the recorded change in device status, to a new position.
- the new position is the initial position when recording the next change in device status. In this sense, the changes in device status and consequently the change in the state of the recorder caused by them are transferred into a further movement of the adding member, added and thus counted.
- the adding member alone may therefore forms a counting member, and the recorder may operate as a switching member.
- the display structure on the device may be fixedly connected to the adding member, or may be formed integrally with the adding member.
- the reducing gear is multi-staged with at least two reducing stages, such that a larger number of changes in state may be counted, with a compact design of the adder.
- Each of the stages may be formed as an adding stage.
- the movement of the adding member may for example be a rotational movement about a rotational axis or, as applicable, a back-and-forth linear movement, the path distance of which—in the case of rotational movement measured at the circumference—is transferred into a shorter path distance of a subsequent gear member.
- the display structure may form an adding output member of the adder.
- the adding member forms an adding input member of the multi-staged embodiment of the adder.
- the adding input member and the adding output member are preferably coupled to each other via one or more intermediate members.
- the adder may be formed as a toothed wheel gear or include a toothed wheel, gear or the like as one stage or as a number of toothed wheel stages in which an input speed is reduced to an output speed.
- the recorder and the adding input member may be mounted and coupled to each other such that the recorder may be moved back and forth between two end positions and causes the adding input member to move further when moving in at least one of the two directions.
- the coupling is formed as an adjusting engagement which the recorder passes into through its movement with the adding input member.
- the back-and-forth recording movement of the recorder is preferably converted in the adjusting engagement into a rotational movement of the adding input member.
- the recorder may instead complete a rotational movement itself during recording and thus roll off on the adding input member, in order to rotate it in this way. Such an adjusting engagement is useful when dosage setting processes are counted by means of the recorder.
- the rotational movement of the adding input member may be reduced with respect to its speed in a multi-staged reducing gear, by the adding input member driving an adding intermediate member in another adjusting engagement, such that the adding intermediate member performs only a partial revolution per revolution of the adding input member.
- the adder may also have multiple recorders, one of which for example performs a rotational recording movement and the other a translational recording movement. The multiple recorders may act on the same adding input member, in succession.
- the recorder slidably shifts in response to a change in the apparatus and engages with the adding input member and rotatably shifts the adding input member from a first position to a second position.
- the display structure is rotatable in response to the adding input member shifting from the first position to the second position.
- the recorder includes a restoring member such as a spring for tensing the recorder in an advancing position.
- the adding output structure includes an annular disk mounted by the adder casing, and is rotatable relative to a portion of the apparatus.
- a recorder is secured against rotating by the adder casing.
- the adder casing may further include rotational guide for guiding the adding input member.
- the adding input member includes a ring with one or more sets of toothings (which also may be referred to as teeth, and which may take the form of any suitable texturing or meshing structures).
- the sets of toothings may be situated opposite one or more toothings situated on a recorder.
- the recorder slides in a recording motion and the toothings of the recorder passes into a toothed engagement with one or more sets of adding input member toothings, where the adding input member is rotatable from a first position to a second position in response to the recorder recording motion.
- the recorder is slidable in response to an apparatus container change.
- an intermediate member for coupling the adding input member to the adding output structure is included.
- the adder is mounted to the administering apparatus, such that the adder casing is connected to a triggering element of the apparatus.
- FIG. 1 depicts an injection apparatus according to an embodiment of the present invention, in a perspective view
- FIG. 2 depicts an injection apparatus according to an embodiment of the present invention with the coupler open, in a longitudinal section;
- FIG. 3 depicts an injection apparatus according to an embodiment of the present invention with the coupler closed;
- FIG. 4 depicts a detail from the injection apparatus of FIG. 2 , an according to an embodiment of the present invention
- FIG. 5 depicts a detail from the injection apparatus of FIG. 3 , an according to an embodiment of the present invention
- FIG. 6 depicts an injection apparatus according to an embodiment of the present invention after a dosage has been set
- FIG. 7 depicts an injection apparatus according to an embodiment of the present invention after a reservoir has been emptied
- FIG. 8 depicts a decoupling member and a casing part of an injection apparatus according to an embodiment of the present invention
- FIG. 9 depicts a distal portion of the injection apparatus with the casing parts connected according to an embodiment of the present invention.
- FIG. 10 depicts a distal portion of the injection apparatus while the casing parts are being detached according to an embodiment of the present invention
- FIG. 11 depicts an injection apparatus of an exemplary embodiment, with the coupler open, in a longitudinal section
- FIG. 12 depicts an injection apparatus with the coupler closed, in a different longitudinal section according to an embodiment of the present invention
- FIG. 13 depicts a detail from FIG. 11 according to an embodiment of the present invention.
- FIG. 14 depicts a detail from FIG. 12 , according to an embodiment of the present invention.
- FIG. 15 depicts an injection apparatus after a dosage has been set, according to an embodiment of the present invention.
- FIG. 16 depicts an injection apparatus after the reservoir has been emptied, according to an embodiment of the present invention
- FIG. 17 depicts an injection apparatus of the second exemplary embodiment, with the casing parts detached from each other, according to an embodiment of the present invention
- FIG. 18 depicts a detail from FIG. 17 , according to an embodiment of the present invention.
- FIG. 19 depicts an injection apparatus according to an embodiment of the present invention.
- FIG. 20 depicts a proximal part of the injection apparatus of the third exemplary embodiment, with the coupler open, according to an embodiment of the present invention
- FIG. 21 depicts the injection apparatus of the third exemplary embodiment, with the coupler closed, according to an embodiment of the present invention
- FIG. 22 depicts a proximal part of the injection apparatus of the third exemplary embodiment, when correcting the dosage, according to an embodiment of the present invention
- FIG. 23 depicts a proximal part of the injection apparatus of the third exemplary embodiment, after the reservoir has been emptied, according to an embodiment of the present invention
- FIG. 24 depicts a blocking member and a stopping member of the third exemplary embodiment, according to an embodiment of the present invention
- FIG. 25 depicts a service life timer, according to an embodiment of the present invention.
- FIGS. 26-38 depict a module and components of the service life timer, in various views and sections, according to an embodiment of the present invention.
- fastening, mounting, attaching or connecting the components of devices of the present invention unless specifically described as otherwise, conventional fasteners such as screws, rivets, toggles, pins and the like may be used.
- Other fastening or attachment means appropriate for connecting components include friction fitting, adhesives, welding and soldering, the latter particularly with regard to electrical or processing components or systems of the devices.
- Any suitable mechanical or power communicating links, linkages or transmission may be used.
- Any suitable electronic, electrical, communication, computer or processing components may be used, including any suitable electrical components and circuitry, wires, wireless components, sensors, chips, boards, micro-processing or control system components, software, firmware, hardware, etc.
- FIG. 1 shows an injection apparatus of a first exemplary embodiment.
- the injection apparatus comprises a first casing part 1 and a second casing part 4 which are detachably connected to each other.
- the casing parts 1 and 4 are screwed to each other.
- the injection apparatus is formed as a slim injection pen.
- the casing part 1 serves to accommodate a container 2 filled with a fluid product and in this sense forms a reservoir
- the casing part 4 serves as a bearer for a dosing and drive means, a dosing member 18 of which may be seen.
- the casing part 4 is breached in the region of the dosing member 18 , such that a user has direct access to the dosing member 18 .
- the dosing member 18 is mounted such that it may be rotated about a central longitudinal axis of the apparatus, and formed as a sleeve which is ribbed on its outer circumference so as to be user-fiendly.
- a dosage display 20 may also be seen, which is laterally placed through a breach in the shell of the casing part 4 .
- FIG. 2 shows the injection apparatus of the first exemplary embodiment, in a longitudinal section.
- the container 2 is accommodated in the casing part 1 .
- a piston 3 is accommodated such that it can be moved in an advancing direction V.
- the piston 3 seals the container 2 , fluid-proof, at its proximal end.
- Advancing the piston 3 in the advancing direction V displaces and delivers product through an outlet of the container 2 .
- the outlet for example, may include an injection needle protruding into the outlet and fastened to the distal end of the casing part 1 by means of a needle holder.
- the container 2 is formed in the manner of conventional ampoules.
- the casing part 1 directly forms a container holder; in the exemplary embodiment, an ampoule holder.
- the proximal end of the casing part 1 protrudes into the casing part 4 and is screwed to the casing part 4 .
- the casing part 4 accommodates a piston rod 15 and the dosing and drive means which is formed as a dosing and drive mechanism.
- the dosing and drive means includes a drive member 5 and a coupler which in a coupled state, i.e. in a coupler engagement, couples the drive member 5 to the piston rod 15 .
- the piston rod 15 together with the piston 3 , forms a conveying means.
- coupler members 6 - 10 transfer a drive force exerted on the drive member 5 onto the piston rod 15 .
- No coupler engagement exists in FIG. 2 , such that the piston rod 15 is decoupled from the drive member 5 .
- the user may set the product dosage to be administered, by a dosing movement of the dosing member 18 ; in the exemplary embodiment, a rotational movement.
- the drive member 5 is sleeve-shaped. On its shell outer area, it comprises a thread about a threaded axis R pointing in the advancing direction V. Via this thread, the drive member 5 is in threaded engagement with coupler input member 6 .
- the coupler input member 6 is also sleeve-shaped and provided with a corresponding inner thread for the threaded engagement. The thread pitch in the threaded engagement is large enough that self-locking cannot occur.
- the dosing member 18 surrounds the coupler input member 6 and is connected to the coupler input member 6 such that it is secured against rotating and cannot be moved axially.
- the piston rod 15 protrudes into the drive member 5 and the coupler input member 6 .
- the piston rod 15 is provided with an outer thread over its axial length. Via the outer thread, it is in threaded engagement with a coupler output member 9 which is provided with a corresponding inner thread. These two threads also exhibit a thread pitch which prevents self-locking in the threaded engagement. In one example, the thread pitch is less than the thread pitch in the threaded engagement between the drive member 5 and the coupler input member 6 .
- a coupler sleeve 8 is connected to the coupler output member 9 such that it is secured against rotating and cannot be moved axially.
- the coupler sleeve 8 and the coupler output member 9 may be regarded as an integral component with respect to the movements between the drive member 5 and the piston rod 15 ; however, in order to accommodate an equalizing spring 17 , they are embodied in two parts and fixedly connected to each other.
- the coupler output member 9 and the coupler sleeve 8 are mounted in the casing part 4 such that they may be rotated about the threaded axis R of the coupler output member 9 but cannot be moved axially. In the threaded engagement, the piston rod 15 protrudes through the coupler output member 9 and protrudes into the coupler sleeve 8 .
- the equalizing spring 17 is clamped between a proximal end of the coupler sleeve 8 and a proximal end of the piston rod 15 and acts on the piston rod 15 in the advancing direction V as a pressure spring.
- the equalizing spring 17 presses onto the piston rod 15 via a disc 15 a which is supported such that it may be rotated on the piston rod 15 and forms a flange of a sleeve placed onto the piston rod 15 .
- the piston rod 15 is linearly guided in and counter to the advancing direction V in a linear guide 4 a , such that it cannot be rotated relative to the casing part 1 .
- the drive member 5 is also linearly guided relative to the casing part 4 such that it may be moved in and counter to the advancing direction V, for which purpose the casing part 4 directly forms a linear guide 4 b.
- the threaded axis of the piston rod 15 forms the main movement axis of the device. It forms a rotational axis R for the rotational drive movement of the coupler input member 6 and, via the coupler intermediate member 7 , the coupler output member 9 . It forms both threaded axes. It also forms the translational axis for the piston rod 15 and the drive member 5 .
- the coupler also includes a coupler intermediate member 7 and a coupler restoring member 10 which is formed as a pressure spring and charges the coupler intermediate member 7 with an elasticity force acting counter to the advancing direction V.
- the restoring member 10 is clamped between the coupler output member 9 and the coupler intermediate member 7 .
- the restoring member 10 ensures, via the coupler intermediate member 7 , that the coupler engagement is released. This state is shown in FIG. 2 .
- the coupler input member 6 is pressed in the advancing direction V until it abuts against the coupler intermediate member 7 , and is pressed into a proximal end position by the restoring member 10 via the coupler intermediate member 7 .
- the restoring member 10 holds the coupler input member 6 in a holding position relative to the coupler output member 9 and the coupler sleeve 8 fastened to it.
- the restoring member 10 and the coupler intermediate member 7 thus form a holding means, acting in a non-positive lock, for the coupler input member 6 .
- FIG. 3 shows the injection apparatus in a coupled state.
- a coupler engagement exists between the coupler input member 6 and the coupler sleeve 8 .
- the coupler input member 6 and the coupler sleeve 8 form engaging elements which, in the coupler engagement, establish a rotationally secured connection between the two members 6 and 8 about the threaded axis R pointing in the advancing direction V.
- the engaging elements co-operate as grooves and springs or toothings which are formed parallel to the advancing direction V and evenly distributed about the threaded axis R.
- FIGS. 4 and 5 show the region of the coupler engagement in detail.
- FIG. 4 shows the apparatus in the decoupled state
- FIG. 5 shows the apparatus in the coupled state.
- FIG. 4 thus corresponds to FIG. 2
- FIG. 5 thus corresponds to FIG. 3 .
- the coupler input member 6 is retracted from the coupler sleeve 8 counter to the advancing direction V, such that the coupler input member 6 may be freely rotated relative to the coupler sleeve 8 , and therefore the coupler output member 9 fixedly connected to it.
- the coupler output member 9 is simultaneously connected, such that it cannot be rotated, to the casing part 4 via the coupler sleeve 8 , the coupler intermediate member 7 and a decoupling member 11 .
- the coupler intermediate member 7 is provided with engaging elements 7 b on an inner area radially facing the coupler sleeve 8
- the coupler sleeve 8 is provided with corresponding engaging elements 8 b .
- the coupler intermediate member 7 is provided with engaging elements 7 b on an outer circumferential area, and the decoupling member 11 is provided with radially facing engaging elements 11 a on a shell inner area which, in the decoupled state, interlock with each other—like the engaging elements 7 b and 8 b —in the manner of grooves and springs or toothings parallel to the advancing direction V.
- the coupler intermediate member 7 in its rotationally secured engagement with the coupler sleeve 8 and its rotationally secured engagement with the decoupling member 11 , may be moved axially in and counter to the advancing direction V, wherein the engagement with the decoupling member 11 is released when it moves in the advancing direction V.
- the drive member 5 If the drive member 5 is operated by exerting a pressure force on a triggering element 16 in the advancing direction V, the drive member 5 and the coupler input member 6 together complete an axial coupler stroke of length X.
- the coupler input member 6 pushes the coupler intermediate member 7 in the advancing direction V, against the restoring elasticity force of the restoring member 10 .
- the engaging elements 6 a and 8 a pass into engagement with each other, while the coupler intermediate member 7 simultaneously moves relative to the decoupling member 11 until it passes out of the rotationally secured engagement with the decoupling member 11 .
- the coupler intermediate member 7 remains in the rotationally secured engagement with the coupler sleeve 8 .
- the coupler movement is limited by a stopper of the triggering element 16 on the coupler sleeve 8 ; in the exemplary embodiment, on its proximal facing area.
- FIG. 5 shows the injection apparatus in the coupled state.
- the engaging elements 6 a and 8 a are axially superimposed, such that the coupler engagement is established as a rotationally secured engagement between the coupler input member 6 and the coupler sleeve 8 .
- the engagement between the coupler intermediate member 7 and the decoupling member 11 is not released until the coupler engagement is securely established.
- the user rotates the dosing member 18 , which locks in easily releasable locking positions.
- the dosing member 18 is connected to the coupler input member 6 such that it is secured against rotating and also cannot be moved axially, such that the latter rotates with it.
- the drive member 5 guided linearly in and counter to the advancing direction V at 4 b is moved, by the dosing movement of the coupler input member 6 , in the proximal direction and then protrudes out of the casing part 4 .
- the axial dosing path of the drive member 5 follows from the rotational angle by which the dosing member 18 is rotated and the thread pitch in the threaded engagement between the drive member 5 and the coupler input member 6 which abuts against the coupler intermediate member 7 in the advancing direction V and against the casing part 4 counter to the advancing direction V.
- FIG. 6 shows the injection apparatus with the container 2 still completely filled, after a first dosage has been set.
- the user penetrates the skin with the injection needle, for a subcutaneous injection.
- the user operates the drive member 5 by pressing it in the advancing direction V, into the casing part 4 .
- the drive member 5 slaves the coupler input member 6 , against the elastic restoring force of the restoring member 10 , until the coupler engagement with the coupler sleeve 8 is established and the rotationally secured engagement between the coupler intermediate member 7 and the decoupling member 11 is released.
- the coupler stroke X is complete and a delivery stroke follows as the second portion of the drive movement.
- the drive member 5 is pressed further in the advancing direction V. Since the coupler input member 6 cannot perform any further movement in the advancing direction V once it abuts axially against the coupler intermediate member 7 , it rotates—in the threaded engagement with the drive member 5 which is guided such that it is secured against rotating—about the common threaded axis R.
- the coupler input member 6 slaves the coupler sleeve 8 , which slaves the coupler output member 9 .
- the coupler sleeve 8 is held in the casing part 4 , together with the coupler output member 9 , such that it cannot be moved axially.
- the rotational movement of the coupler output member 9 advances the piston rod 15 , via the threaded engagement with the piston rod 15 and its rotationally secured linear guide at 4 a , and thus causes the delivery movement of the piston rod 15 and together with it the piston 3 .
- the injection button 16 passes into abutting contact against the coupler sleeve 8 in the course of the drive and delivery movement ( FIG. 3 ), the delivery process is complete.
- the restoring member 10 moves the coupler input member 6 , via the coupler intermediate member 7 , back to the holding position retracted out of the coupler engagement, as shown in FIGS. 2 and 4 .
- the coupler input member 6 and together with it the drive member 5 , the dosing member 18 and the dosage display 20 are decoupled from the coupler output member 9 and thus from the piston rod 15 by the retracting movement of the coupler input member 6 .
- the piston rod 15 is again connected to the casing part 4 , such that it is secured against rotating, via the returning coupler intermediate member 7 and decoupling member 11 .
- FIG. 7 shows the injection apparatus at the end of a final delivery which has emptied the container 2 .
- the casing part 1 is detached from the casing part 4 ; in the exemplary embodiment, by a screwing movement.
- the decoupling member 11 is automatically moved relative to the casing part 4 , counter to the direction of the coupler movement of the coupler input member 6 ; in the exemplary embodiment, counter to the advancing direction V.
- the casing part 4 mounts the decoupling member 11 accordingly.
- the axial path which the decoupling member 11 thus travels relative to the casing part 4 is as long as the coupler stroke X, such that once the casing parts 1 and 4 have been detached, the decoupling member 11 lying axially opposite the coupler input member 6 blocks it, and the coupler input member 6 may no longer be moved in the advancing direction V, at least not into the coupler engagement with the coupler sleeve 8 .
- Blocking the coupler input member 6 in the disengaged position prevents the coupler output member 9 from being able to pass into a rotationally secured connection with the casing part 4 and so prevent the piston rod 15 from being able to be retracted. In other words, it ensures that the piston rod 15 may be retracted into the casing part 4 , without being blocked.
- FIG. 8 shows the decoupling member 11 and the first casing part 1 in a perspective view.
- the decoupling member 11 is a sleeve part and comprises, in a distal portion, three engaging elements 12 protruding radially inwards and, in a proximal portion, a fixing element 13 protruding radially outwards.
- FIG. 9 shows the casing part 1 and a connecting portion of the casing part 4 , wherein the hidden decoupling member 11 is shown by a broken line.
- the decoupling member 11 is accommodated in the connecting portion of the casing part 4 such that it may be rotated and moved axially.
- Its relative mobility is determined by an axial guide 4 e and a circumferential guide 4 c , along which the fixing element 13 moves in succession when the casing part 1 is detached from the casing part 4 .
- the circumferential guide 4 c extends at a right angle to the axial guide 4 e , in the circumferential direction about the screw axis. It is formed as a breach or cavity in the casing part 4 .
- the decoupling member 11 is in a guiding engagement with the casing part 1 .
- one guiding curve 1 a per engaging element 12 is formed on a shell outer area of the casing part 1 and guides the engaging element 12 and thus the decoupling member 11 when the casing parts 1 and 4 are detached.
- Another guiding curve 1 a spaced in parallel, guides the decoupling member 11 accordingly, when the casing parts 1 and 4 are connected ( FIG. 10 ).
- the guiding curve 1 a runs obliquely, i.e.
- the pitch measures about 45° and is constant.
- the pitch measurement may be selected from the entire range larger than 0° and smaller than 180° and, as applicable, may also be variable, as long as the relative movement required for detaching the casing parts 1 and 4 —in the exemplary embodiment, a screwing movement—causes a movement of the decoupling member 11 counter to the coupler movement X to be performed by the coupler input member 6 for coupling.
- a distal portion of the guiding curve 1 a runs axially, such that when the casing parts 1 and 4 are screwed further apart, the fixing element 13 is moved along the circumferential guide 4 c .
- the fixing element 13 slides over a fixing element 4 d in the region of the circumferential guide 4 c .
- the fixing element 4 d is formed as a cam on a strip portion of the casing part 4 .
- the strip portion acts as a spiral spring which is fixedly clamped on both sides and elastically gives when the fixing element 13 moves over the fixing element 4 d , in order to then spring back again into its initial position and form a releasable locking engagement for the decoupling member 11 .
- the fixing element 13 In the locking position, the fixing element 13 abuts the fixing element 4 d in one circumferential direction and in the other circumferential direction abuts a collar formed in the circumferential guide 4 c and is thus fixed in both circumferential directions.
- FIG. 10 shows the two casing parts 1 and 4 and the decoupling member 11 , after its fixing element 13 has been moved behind the fixing element 4 d of the casing part 4 .
- the decoupling member 11 is in the releasable locking engagement with the casing part 4 via the fixing elements 4 d and 13 and in this way is axially fixed on the casing part 4 such that it is secured against rotating.
- the decoupling member 11 blocks the coupler input member 6 and thus ensures that the drive member 5 and the piston rod 15 are decoupled.
- its engaging element 12 moves out of the guiding engagement with the guiding curve 1 a when the casing parts 1 and 4 are screwed further apart.
- the guiding curve 1 a is shaped accordingly.
- the dosage display 20 of the first exemplary embodiment is coupled to the drive member 5 via a display coupling member 21 and the coupler input member 6 .
- the display coupling member 21 is connected to the coupler input member 6 such that it is secured against rotating, by being able to move on the coupler input member 6 and relative to it in and counter to the direction of the coupler movement X, forming a ring in the exemplary embodiment.
- the display coupling member 21 may be rotated with respect to the casing part 4 about the rotational axis R, but is held such that it cannot be moved axially relative to the casing part 4 .
- the display coupling member 21 circumferentially comprises a toothing, which in the exemplary embodiment is formed as a conical toothing, via which it is in toothed engagement with a gear of the dosage display 20 , in order to introduce the dosing movement and also the drive movement into the gear.
- FIGS. 11 to 18 show an injection apparatus of a second exemplary embodiment.
- the injection apparatus of the second exemplary embodiment exhibits some modifications as compared to the apparatus of the first exemplary embodiment with regard to the coupling and decoupling of the drive member 5 and the piston rod 15 .
- the drive member 5 and the piston rod 15 and the manner in which they cooperate remains the same.
- the functionally identical components are provided with the same reference numbers as in the first exemplary embodiment. In order to indicate modifications, the relevant components are provided with the same reference numbers, but apostrophized.
- FIG. 11 shows the injection apparatus in its resting state, in which the drive member 5 is decoupled from the piston rod 15 .
- the first casing part 1 is covered by a protective cap 37 which is connected to the casing part 4 and removed for administering the product.
- the coupler engagement is established and released between the modified coupler input member 6 ′ and the modified coupler intermediate member 7 ′.
- FIG. 12 shows the injection apparatus of the second exemplary embodiment in its coupled state, which is established by charging the triggering element 16 and therefore the drive member 5 and the coupler input member 6 ′ with a drive force acting in the advancing direction V.
- the protective cap 37 has been replaced by a casing part 38 which is placed onto the casing part 4 and snapped onto it.
- the casing part 38 mounts a needle protection 39 , for example, in the form of a needle protecting sleeve, such that it may be elastically moved counter to the advancing direction V.
- the needle protection 39 springs counter to the advancing direction V, into the casing part 38 ; in a reversal of this movement, the needle penetrates through a distal opening of the needle protection 39 .
- FIGS. 13 and 14 show the region of the coupler engagement in detail, wherein FIG. 13 stands for the decoupled state and FIG. 14 stands for the coupled state.
- the engaging elements 6 a and 7 c between which the coupler engagement is established exhibits an inclination with respect to the advancing direction V.
- the engaging elements 6 a and 7 c are each formed in the manner of a conical toothed ring encircling the threaded axis of the piston rod 15 , wherein the coupler input member 6 ′ forms its engaging elements 6 a on its distal end as inner cones, and the coupler intermediate member 7 ′ forms the engaging elements 7 c on its proximal end as outer cones.
- the conical engaging areas are congruent to each other and lie directly opposite each other, axially facing, with the clear distance X. Instead of conical, the coupler areas could also be shaped to be congruently convex/concave.
- the coupler intermediate member 7 ′ may be moved axially and is in engagement with the coupler output member 9 , such that it is secured against rotating, in any axial position. It is again formed as a sleeve part and mounted on the coupler output member 9 such that it may be slid axially. For this purpose, it penetrates through the coupler sleeve 8 ′ which is axially slit accordingly, which however is not visible in the figures.
- the rotationally secured connection is created in a positive lock via engaging elements formed as axially linear toothings.
- the restoring member 10 ′ which is the same in its embodiment and installation but reduced with regard to its function, is tensed between the coupler output member 9 and the coupler intermediate member 7 ′, as in the first exemplary embodiment, and charges the latter with an elasticity force, counter to the advancing direction V.
- the restoring member 10 ′ presses the coupler intermediate member 7 ′ into the rotationally secured engagement with the decoupling member 11 ′.
- the corresponding engaging elements are again indicated as 7 a and 11 a .
- the engaging elements 7 a and 11 a are also formed as conical toothed rings.
- the engagement between the coupler intermediate member 7 ′ and the decoupling member 11 ′ may alternatively be purely in a frictional lock.
- the engaging elements 7 a and 11 a comprise mutually facing congruent frictional areas; in the exemplary embodiment, these would be the mutually facing conical areas.
- the dosing member 18 ′ Another modification exists in the dosing member 18 ′. Unlike the dosing member 18 of the first exemplary embodiment, the dosing member 18 ′ cannot be moved relative to the casing part 4 in the direction of the coupler movement X; in the exemplary embodiment, the axial direction. Instead, the coupler input member 6 ′ is again connected to the dosing member 18 ′ such that it is secured against rotating, but may be moved axially. The rotationally secured engagement between the coupler input member 6 ′ and the dosing member 18 ′ exists in the decoupled state of the drive member 5 and the piston rod 15 and is released in the course of the coupler stroke X, namely directly before the rotationally secured connection between the coupler output member 9 and the casing part 4 is released.
- the coupler input member 6 ′ and the dosing member 18 ′ are provided with engaging elements 6 b and 18 a which are formed on shell areas, radially facing each other, of the two members 6 ′ and 18 ′ in the manner of grooves and springs.
- FIGS. 11 and 12 With respect to the rotationally secured connection between the coupler input member 6 ′ and the dosing member 18 ′, reference may also be made to FIGS. 11 and 12 .
- the rotationally secured connection exists in the decoupled state shown in FIG. 11 , and is released in the coupled state shown in FIG. 12 .
- the restoring member 10 ′ has no effect which separates the coupler members 6 ′ and 9 from each other.
- the holding means of the second exemplary embodiment includes a coupler restoring member 14 , a supporting structure 6 c and the dosing member 18 ′.
- the restoring member 14 charges the coupler input member 6 ′, via the supporting structure 6 c , with an elastic restoring force which counteracts the coupler movement X of the coupler input member 6 ′.
- the restoring member 14 is supported on the dosing member 18 ′ which forms a supporting collar for this purpose.
- the supporting structure 6 c is connected to the coupler input member 6 ′ such that it cannot be moved in or counter to the direction of the coupler movement X. It is formed as a short sleeve with an outer flange on which the restoring member 14 is supported. Counter to direction of the coupler movement X, the supporting structure 6 c abuts with respect to the casing part 4 .
- the coupler movement X moves the coupler input member 6 ′, against the elastic restoring force of the restoring member 14 , into the coupler engagement with the coupler intermediate member 7 ′.
- the restoring member 14 is formed as a pressure spring charged with a pressure force in the direction of the coupler movement X.
- the mode of operation of the modified coupler is the same as the coupler of the first exemplary embodiment.
- the coupler output member 9 is connected, such that it is secured against rotating, to the casing part 4 via the coupler sleeve 8 ′, the coupler intermediate member 7 ′ and the decoupling member 11 ′.
- Operating the injection button 16 and consequently performing the coupler stroke X establishes the coupler engagement, in the second exemplary embodiment between the coupler input member 6 ′ and the coupler intermediate member 7 ′.
- the engaging elements 6 a and 7 c interlock with each other, such that the coupler input member 6 ′ is connected, such that it is secured against rotating, to the coupler output member 9 via the coupler intermediate member 7 ′ and the coupler sleeve 8 ′. Only once the rotationally secured engagement has been established is the coupler intermediate member 7 ′ moves out of engagement with the decoupling member 11 ′ by the coupler input member 6 ′ pressing in the advancing direction V, such that the coupler output member 9 may freely rotate about the threaded axis R formed with the piston rod 15 and the coupler engagement is completely established.
- FIG. 14 shows the injection apparatus in its coupled state, i.e., in the coupler engagement
- FIGS. 15 and 16 correspond generally to FIGS. 6 and 7 of the first exemplary embodiment, such that reference may be made to FIGS. 6 and 7 .
- FIG. 17 shows the injection apparatus of the second exemplary embodiment while the reservoir 2 is being exchanged.
- the casing part 1 is already accommodating the new reservoir 2 .
- the casing part 1 may be moved towards the casing part 4 using the piston 3 which proximally seals the reservoir 2 .
- the piston rod 15 which freely protrudes out of the casing part 4 is moved back by the pressing piston 3 in the threaded engagement with the coupler output member 9 which may be freely rotated but is axially fixed.
- the piston rod 15 Due to the rotationally secured linear guide 4 a , which in the second exemplary embodiment is formed by a coupler receptacle which is inserted into the casing part 4 such that it is secured against rotating, the piston rod 15 completes an axial linear movement when retracted, while the coupler output member 9 freely rotates, together with the coupler sleeve 8 ′, about the common threaded axis.
- the piston rod 15 may also be moved back beforehand by pressing directly on its plunger.
- FIG. 18 shows the coupler region, with the decoupling member 11 ′ situated in the decoupling position, in detail.
- the function of the decoupling member 11 ′ corresponds to that of the first exemplary embodiment, namely blocking the coupler input member 6 ′ in the retracted axial position.
- the dosing movement and the drive movement are also introduced into the gear of the dosage display 20 ′ via the coupler input member 6 ′ and a display coupling member 22 in the second exemplary embodiment.
- the display coupling member 22 is also connected to the coupler input member 6 ′, such that it is secured against rotating, and cannot be moved relative to the casing part 4 in and counter to the direction of the coupler movement X.
- FIGS. 19 to 24 show a third exemplary embodiment of the injection apparatus, in which during administering, the drive force for delivering the product is not applied manually but rather by a drive member 25 formed as a drive spring.
- the drive member 25 is tensed by setting the dosage to be administered.
- the spring energy absorbed when setting the dosage is released when the apparatus is triggered and converted into advancing the piston rod 15 .
- FIG. 19 shows the injection apparatus of the third exemplary embodiment, complete with the assembled casing part 38 and the needle protection 39 accommodated in it, which may be slid counter to the advancing direction V, against the force of a restoring spring.
- FIGS. 20 and 21 show the casing part 4 with the components of the injection apparatus accommodated in it; FIG. 20 in a resting state comparable to the preceding exemplary embodiments, in which the dosage may be set, and FIG. 21 in the coupler engagement. Where nothing different is said below, reference is made in particular to FIGS. 20 and 21 .
- the drive member 25 is a spiral spring acting as a torsion spring, comprising spring windings which encircle the threaded axis R of the threaded engagement between the coupler output member 9 and the piston rod 15 .
- the spring windings are arranged one over the other, radially with respect to the spring windings; they exhibit a zero pitch with respect to the threaded axis R.
- An inner end of the spring windings is fastened to the coupler input member 6 ′, and an outer end is fastened to a supporting structure 26 which is connected to the casing part 4 such that it may be moved in the direction of the coupler movement X but is secured against rotating.
- the supporting structure 26 is connected to the coupler input member 6 ′ such that it cannot be moved in and counter to the direction of the coupler movement X.
- the coupler input member 6 ′ may be rotated about the threaded axis R relative to the supporting structure 26 .
- Another supporting structure 6 d is connected to the coupler input member 6 ′ such that it cannot be moved in and counter to the direction of the coupler movement X; in the exemplary embodiment, the coupler input member 6 ′ and the supporting structure 6 d are formed integrally.
- the drive member 25 is axially enclosed by the supporting structures 6 d and 26 .
- the functionality of the coupler corresponds to that of the second exemplary embodiment, such that the same reference indicators are used for the coupler members 6 ′- 10 ′ and the decoupling member 11 ′. Unlike the coupler of the second exemplary embodiment, however, the coupler sleeve 8 ′ therein has been omitted.
- the coupler intermediate member 7 ′ is directly in an engagement with the coupler output member 9 which transfers the rotational drive movement of the coupler input member 6 ′ onto the coupler output member 9 .
- the 20 ′′ indicates a dosage display which is coupled to the coupler input member 6 ′ via a display coupling member 23 and, like the display coupling members 21 and 22 of the other exemplary embodiments previously, is connected to the coupler input member 6 ′, such that it is secured against rotating.
- the display coupling member 23 cannot be moved in and counter to the direction of the coupler movement X relative to the casing part 4 .
- the rotationally secured connection of the display coupling member 23 exists both in the decoupled and in the coupled state of the device.
- a rotational block is formed between the coupler input member 6 ′ and the casing part 4 .
- the rotational block exists between a first blocking member 24 and a second blocking member 34 .
- the blocking member 24 is connected to the coupler input member 6 ′, such that it is secured against rotating.
- the blocking member 34 is connected to the casing part 4 , such that it is secured against rotating but may be moved in and counter to the direction of the coupler movement X relative to the casing part 4 and the coupler input member 6 ′.
- the facing areas of the blocking members 24 and 34 which contact each other in the blocking engagement, form a ratchet which allows a rotational movement of the coupler input member 6 ′ which tenses the drive member 25 and prevents a rotational movement in the opposite direction.
- FIG. 24 depicts the coupler input member 6 ′ together with the blocking member 24 mounted on it, such that it is secured against rotating, the display coupling member 23 connected to the coupler input member 6 ′, such that it is secured against rotating, and a connecting part 33 connected to the input member 6 ′ such that it cannot be moved.
- the display coupling member 23 forms a units counting ring of the dosage display 20 ′′ and is suitably coupled to a tens counting ring in order to display the dosage set.
- the blocking member 24 On proximal facing side facing the blocking member 34 , the blocking member 24 is provided with blocking teeth 24 a which are arranged evenly about the axis R and in the blocking engagement co-operate with counter teeth of the blocking member 34 , in order to form the rotational block with respect to the drive movement.
- a shell outer area of the blocking member 24 is provided with a thread 24 b , the threaded axis of which coincides with the threaded axis R of the piston rod 15 .
- a stopping member 27 engages with the thread 24 b .
- the stopping member 27 is guided such that it may be linearly moved parallel to the threaded axis R; in the exemplary embodiment, in an axial groove on the inner shell area of the casing part 4 .
- the blocking member 24 forms a rotational stopper 24 c for the stopping member 27 , which limits the drive movement of the coupler input member 6 ′ which advances the piston rod 15 .
- It forms another rotational stopper 24 d for the stopping member 27 , which determines the maximum dosage which may be delivered and set.
- Another stopping member 27 is arranged on the other side of the threaded axis R, opposite the stopping member 27 which may be seen in the view in FIG. 23 , and co-operates in the same way with two other rotational stoppers 24 c and 24 d .
- the thread 24 b is double-threaded.
- the stopping members 27 simultaneously abut against the respectively assigned rotational stoppers 24 c and 24 d , as may be seen in the cross-sectional representation in FIG. 23 for the rotational stoppers 24 c .
- the rotational stoppers 24 c determine a zero dosage position and the rotational stoppers 24 d determine a maximum dosage position.
- the holding means is formed in a third variant. It includes a coupler restoring member 19 , as well as the display coupling member 23 and the blocking member 24 .
- the restoring member 19 is supported on the casing part 4 via the display coupling member 23 in the direction of the coupler movement X and by the blocking member 24 counter to the direction of the coupler movement X.
- the restoring member 19 presses the blocking member 24 until it abuts against the connecting part 33 .
- the connecting part 33 Since the connecting part 33 is connected to the coupler input member 6 ′ such that it cannot be moved in and counter to the direction of the coupler movement X, the restoring member 19 thus exerts an elastic restoring force, acting counter to the direction of the coupler movement X, on the coupler input member 6 ′ via the blocking member 24 and the connecting part 33 , said elastic restoring force holding the coupler input member 6 ′ in the holding position retracted out of the coupler engagement. It again acts as a pressure spring.
- the blocking member 24 is a sleeve part comprising an outer shell forming the thread 24 b , an inner shell serving to mount it on the coupler input member 6 ′ such that it is secured against rotating, and a base connecting the two shells, on which the blocking teeth 24 a are formed.
- the restoring member 19 protrudes into the blocking member 24 which is cup-shaped in this way, and is supported on the base of the blocking member 24 .
- the restoring member 19 not only presses the blocking member 24 until it abuts against the connecting part 33 , but also until it abuts against the casing part 4 . Abutting in this other way prevents the blocking member 24 from being able to be moved counter to the direction of the coupler movement X beyond the holding position assumed in FIG. 20 .
- the blocking member 24 may thus be moved relative to the coupler input member 6 ′, against the restoring elasticity force of the restoring member 19 , in the direction of the coupler movement X.
- the coupler input member 6 ′ may be moved counter to the direction of the coupler movement X relative to the blocking member 24 abutting against the casing part 4 .
- the equalizing spring 17 supports the restoring member 19 in its function of holding the coupler input member 6 ′ in the holding position.
- the equalizing spring 17 may replace the restoring member 19 for retracting the coupler members 6 ′, 7 ′ and 9 .
- the equalizing spring 17 may be weak enough that, at least once it has been partially relaxed, it may no longer hold the coupler members 6 ′- 9 in the holding position, and thus may no longer reliably hold the coupler in the decoupled state.
- a triggering element 28 is provided for triggering the drive member 25 .
- the triggering element 28 may be moved translationally relative to the casing part 4 in the direction of the coupler movement X—in the exemplary embodiment, the advancing direction V and/or the distal direction—and rotationally about the rotational axis R of the coupler input member 6 ′, which in the exemplary embodiment coincides with the threaded axis R of the piston rod 15 , and is guided in these two movements by the casing part 4 .
- the translational movement in the distal direction establishes the coupler engagement between the coupler input member 6 ′ and the coupler intermediate member 7 ′ and releases the rotational block between the blocking members 24 and 34 , which triggers the drive member 25 , i.e. delivery.
- the translational movement in the advancing direction V is therefore also referred to as the triggering movement in the following.
- the triggering element 28 forms the dosing member of the third exemplary embodiment.
- the rotational movement of the triggering element 28 relative to the casing part 4 sets the product dosage which may be delivered by the next delivery process. This movement is also referred to as the dosing movement in the following. From the zero dosage position, which is shown in FIG. 20 and determined by the stopping members 27 abutting the rotational stoppers 24 c of the blocking member 24 which limit the drive movement of the coupler input member 6 ′, the dosage may be set by rotating the triggering element 28 in the direction of the rotational direction arrow indicated, the dosing direction.
- the rotational dosing movement of the triggering element 28 is transferred onto the coupler input member 6 ′ via an inner part 29 , which is connected to the triggering element 28 such that it is secured against rotating and shifting or is formed integrally with it, and the connecting part 33 .
- the inner part 29 and the connecting part 33 are in an engagement with each other, such that they are secured against rotating, and the connecting part 33 is connected to the coupler input member 6 ′ such that it is secured against rotating.
- the inner part 29 and the connecting part 33 are provided with an inner toothing 29 a and an outer toothing 33 a which interlock with each other in the resting state of the apparatus and may be axially shifted with respect to each other.
- the triggering element 28 is arranged in the proximal end region of the casing part 4 so as to be user-friendly. Its outer sleeve part surrounds the casing part 4 . A base of the triggering element 28 forms a proximal end of the injection apparatus.
- the triggering element 28 may be operated as a turning button and is ribbed on its outer shell area for this purpose. For triggering, it may be operated as a push button.
- the triggering element 28 locks with the casing part 4 in discrete positions corresponding to the dosage units.
- a stopper element 29 b facing a proximal facing area of the connecting part 33 projects radially inwards from the inner part 29 .
- a clear distance remains between the connecting part 33 and the stopper element 29 b , which is just large enough that the rotational block between the inner part 29 and the connecting part 33 is released during the triggering movement of the triggering element 28 , before the stopper element 29 b terminates the relative movement of the triggering element 28 relative to the connecting part 33 by abutting contact.
- the second blocking member 34 is tensed in the blocking engagement with the blocking member 24 by means of a blocking spring 31 .
- the blocking spring 31 is supported in the direction of the coupler movement X on the blocking member 34 and counter to the coupler movement X on a casing part 30 which is fixedly connected to the casing part 4 .
- Another spring 32 arranged between the inner part 29 and the blocking member 34 , tenses the triggering element 28 relative to the blocking member 34 into a proximal end position.
- the blocking member 34 is axially guided, such that it is secured against rotating, by the casing part 4 .
- the casing part 4 forms a distal and a proximal stopper for the mobility of the blocking member 34 .
- the user sets the dosage by rotating the triggering element 28 in the dosing direction.
- the triggering element 28 slaves the connecting part 33 via the rotational block 29 a , 33 a , which for its part slaves the coupler input member 6 ′ which thus completes the same rotational dosing movement as the triggering element 28 .
- Rotating the coupler input member 6 ′ tenses the drive member 25 .
- the stopping member 27 migrates from the stopper 24 c of the thread 24 b determining the zero dosage in the direction of the stopper 24 d determining the maximum dosage ( FIG. 24 ).
- the injection apparatus also offers a convenient way of correcting the dosage, as is clear from a comparison of FIGS. 20 and 22 . If the user has inadvertently set too high a dosage, he/she may correct the dosage by rotating the coupler input member 6 ′ back. For correcting the dosage, he/she pulls the triggering element 28 in the proximal direction. This retracting movement of the triggering element 28 is indicated in FIG. 22 by an arrow, as is the rotational direction for correcting. In the resting state of the apparatus, the inner part 29 and the blocking member 34 are in a slaving engagement with respect to a movement in the proximal direction. The corresponding slaving means are indicated as 29 c and 34 a .
- the slaving means 29 c formed by the inner part 29 and the slaving means 34 a formed by the blocking member 34 grip behind each other and form a latch for the retracting movement of the triggering element 28 .
- the blocking member 34 is thus also moved in the proximal direction, against the force of the blocking spring 31 , and is thus released from the blocking engagement with the blocking member 24 which abuts against the casing part 4 .
- the user may correct the dosage by means of a reverse rotational movement of the triggering element 28 and the still extant rotationally secured engagement between the inner part 29 and the connecting part 33 .
- the user releases the triggering element 28 , it snaps back together with the blocking member 34 due to the effect of the blocking spring 31 in the distal direction and the blocking member 34 thus snaps back into the blocking engagement with the blocking member 24 .
- the user expediently continues to hold the triggering element 28 , which is facilitated by the rotational angular locking positions of the triggering element 28 .
- the user may also let the triggering element 28 snap back and re-dose as applicable.
- the apparatus is placed onto the skin at the desired administering location, and the injection needle is injected.
- the triggering element 28 takes on another function, for which purpose it is coupled to the needle protection 39 ( FIG. 19 ).
- a first phase of injecting the user presses the injection apparatus against the skin, such that the needle protection 39 is moved in the distal direction relative to the casing part 38 .
- this first part of the movement of the needle protection 39 does not yet expose the injection needle; rather, its tip remains short of the needle protection 39 .
- the needle protection 39 abuts against a resisting element, such that it cannot be moved further in the distal direction relative to the casing part 38 .
- the user presses the triggering element 28 in the proximal direction.
- the triggering element 28 releases an abutting contact between the needle protection 39 and the resisting element, such that the injection apparatus, and together with it the injection needle, is moved relative to the needle protection 39 in the direction of the skin, and the injection needle injects.
- the triggering element 28 for injecting the injection needle reference may be made to the U.S. patent application entitled “Attachment Module for an Injection Device Comprising an Engagement Control for a Needle Covering Element,” owned by the owner of the present application and incorporated by reference herein.
- the drive member 25 may be released and the product delivered by pressing further onto the triggering element 28 .
- the triggering element 28 and therefore the inner part 29 is pressed further in the distal direction relative to the connecting part 33 , against the pressure of the spring 32 , such that the rotational block 29 a , 33 a is released.
- the triggering element 28 may rotate idly.
- the stopper element 29 b passes into abutting contact with the connecting part 33 .
- the triggering element 28 presses the connecting part 33 and therefore the coupler input member 6 ′ via the stopper element 29 b , in the direction of the coupler movement X; in the exemplary embodiment, in the advancing direction V. Due to the effect of the spring force of the blocking spring 31 , the blocking member 34 follows this movement, until it abuts against the casing part 4 . Before the blocking member 34 reaches the abutting position, the coupler input member 6 ′ passes into the coupler engagement with the coupler intermediate member 7 ′. The coupler input member 6 ′ presses the coupler intermediate member 7 ′ out of the frictional-lock blocking engagement with the decoupling member 11 ′, against the force of the restoring member 10 ′.
- the blocking member 34 abuts the casing part 4 .
- the triggering element 28 presses the blocking member 24 out of the blocking engagement with the blocking member 34 via the connecting part 33 .
- the rotational drive movement of the coupler input member 6 ′ is initiated due to the drive force of the drive member 25 and is transferred onto the coupler output member 9 via the coupler engagement. Because it is guided—such that it is secured against rotating—in the linear guide 4 a , the piston rod 15 is moved, in the threaded engagement with the coupler output member 9 , in the advancing direction V, and product is delivered. This delivery movement is terminated by the stopping member 27 abutting the stopper 24 c of the blocking member 24 determining the zero dosage.
- FIG. 21 shows the injection apparatus when a zero dosage or a small priming dosage is set, in the coupled state after the rotational block has been released, i.e. after the triggering element 28 has completely performed the triggering movement. If pressure is continuously exerted on the triggering element 28 , the triggering sequence described above progresses automatically from injecting to completely delivering the dosage set.
- FIG. 23 shows the injection apparatus after the container 2 has been emptied.
- the casing part 1 has already been removed from the casing part 4 .
- the piston rod 15 assumes its most distal position.
- the decoupling member 11 ′ blocks the coupler input member 6 ′ in the position retracted from the coupler intermediate member 7 ′.
- the functionality of the decoupling member 11 ′ corresponds to that in the other exemplary embodiments. Unlike the two first exemplary embodiments, however, the casing part 1 and the decoupling member 11 ′ are not directly in a guiding engagement with each other, but rather via an adapter structure 35 .
- the adapter structure 35 is a sleeve in the casing part 4 which is fixed in and counter to the direction of the coupler movement X in the connecting portion, but may be rotated about the central longitudinal axis R of the casing part 4 .
- the adapter structure 35 forms a guiding curve 35 a either as a cavity on or a breach in its shell area facing the decoupling member 11 ′.
- the guiding curve 35 a exhibits the course of a threaded portion.
- the length measured over the circumference and the pitch of the guiding curve 35 a measured with respect to the central longitudinal axis of the casing part 4 are dimensioned such that the decoupling member 11 ′ is moved into the decoupling position shown in FIG.
- the adapter structure 35 forms a linear guide for the casing part 1 .
- the casing part 1 may be inserted into the adapter structure 35 , where a slight frictional lock and correspondingly a sliding guide for the casing part 1 may be present.
- the casing part 1 may not be rotated about the central longitudinal axis of the casing part 4 relative to the adapter structure 35 .
- the engagement which may be rotationally secured, is established right at the beginning of inserting the casing part 1 into the adapter structure 35 .
- the casing part 1 is rotated relative to the casing part 4 and slaves the adapter structure 35 during this rotational movement, until the engaging element 12 of the decoupling member 11 ′ abuts the end of the guiding curve 35 a .
- the rotational movement of the casing part 1 is prevented until its axial abutting position. This may provide a rotational block up until the abutting position may be formed between the casing parts 1 and 4 .
- the movement of the decoupling member 11 ′ caused in the guiding engagement exhibits an axial length which is greater than the length X of the complete coupler movement.
- the decoupling member 11 ′ presses the coupler input member 6 ′ beyond its holding position assumed in the resting state and blocks it in said decoupling position.
- the coupler input member 6 ′ slaves the triggering element 28 via the stopper element 29 b .
- the blocking member 34 is also slaved against the force of the blocking spring 31 , and moved out of the blocking engagement.
- the blocking member 24 may not follow the blocking member 34 , since it is abutting against the casing part 4 .
- Detaching the casing parts 1 and 4 thus releases the rotational block by means of the decoupling mechanism which the casing parts 1 and 4 form with the decoupling member 11 ′ via the adapter structure 35 .
- the coupler input member 6 ′ has not yet assumed the zero dosage position, it is now at the latest rotated into the zero dosage position by the drive member 25 and the dosage display 20 ′′ is zeroed.
- the dosage display 20 ′′ is reset in accordance with the delivered dosage. If the dosage set is not delivered one time, for example because the injection process is aborted or the container 2 is no longer contains the complete dosage set, the user may then read this from the dosage display 20 ′′ which is only partially reset.
- the injection apparatus of the second exemplary embodiment is equipped with a service life timer.
- the service life timer counts the number of changes of the container 2 and indicates to the user when the end of the service life has been reached.
- the service life timer signals to the user that the service life of the injection apparatus has passed.
- Resetting the piston rod 15 serves as an indication that the container 2 has been changed.
- the piston rod 15 forms a first actuator of the service life timer and the triggering element 16 forms a second actuator, which co-operate to switch or further switch the service life timer and in this way count the container changes.
- FIG. 25 shows the proximal end region of the injection apparatus of the second exemplary embodiment, in the state from FIG. 11 .
- the apparatus assumes this state directly after another container 2 has been inserted and the piston rod 15 correspondingly reset, before the triggering element 16 is pressed in.
- the service life timer includes an adder 50 which is formed as a mechanical gear.
- An adder casing 51 which mounts the components of the adder 50 such that they may be moved, is connected to the triggering element 16 , such that it cannot be moved in and counter to the direction of the triggering movement.
- the adder casing 51 is secured against rotating.
- triggering element 16 and display structure 56 may together form output means of the service life timer.
- FIG. 26 shows the adder 50 and the output means as a separate module, separate from the injection apparatus, in a side view.
- the module is simply plugged or snapped into the drive member 5 which is open at the proximal end, such that the module is fixedly connected to the drive member 5 and cannot perform any movements relative to the drive member 5 in and counter to the direction of the coupler movement X or any rotational movements about the rotational axis R.
- FIG. 27 shows the module in a view counter to the advancing direction V.
- FIG. 28 shows the module in the longitudinal section indicated in FIG. 27
- FIGS. 29 and 30 show the cross-sections A-A and B-B indicated in FIG. 26 .
- FIG. 31 shows components of the module without the adder casing 51
- FIG. 32 shows components of the module with the adder casing 51 , each in a perspective view.
- FIG. 33 shows the components of the module individually, in their assembly positions relative to each other. The output means in particular may be seen in FIG. 34 .
- FIG. 35 individually shows an adding input member 54 of the adder 50
- FIG. 36 individually shows an adding intermediate member 55 of the adder 50
- FIGS. 37 and 38 show an adjusting engagement formed between these two components, in detail.
- the service life timer is described below with reference to FIGS. 25 to 38 .
- the adder 50 includes the adder casing 51 and the adder members which it mounts such that they may be moved, namely a recorder 52 , the adding input member 54 , the adding intermediate member 55 , the display structure 56 which simultaneously forms an adding output member, and a recorder restoring member 53 which is formed as a spring member and tenses the recorder 52 in the advancing direction V relative to the adder casing 51 , into a resting position.
- the recorder restoring member 53 acts as a pressure spring which is supported on the recorder 52 in the advancing direction V and on the adder casing 51 counter to the advancing direction V.
- the display structure 56 is formed as an annular disc which is mounted by the adder casing 51 , such that it may be rotated relative to the triggering element 16 , in a space remaining free between the adder casing 51 and the triggering element 16 .
- a journal projects from the annular disc, through an opening of the adder casing 51 , and into a bore of the recorder 52 , in which the recorder restoring member 53 is also accommodated.
- the annular disc of the display structure 56 also forms a hollow wheel for a final stage of the adder 50 .
- the adder casing 51 mounts the recorder 52 such that it may be linearly moved back and forth in and counter to the advancing direction V, and guides it such that it is secured against rotating.
- the adder casing 51 is provided with a circular cylindrical groove encircling the rotational axis R, in which the adding input member 54 is guided such that it may be rotated about the rotational axis R but cannot be moved in and counter to the advancing direction V.
- Other rotational guides for example a groove in the adding input member 54 and a circumferential stay on the casing 51 , are also conceivable.
- the adding input member 54 is shaped as a ring and provided on both axial facing sides, circumferentially in each case, with a toothing 54 a and 54 b of serrated teeth in an even separation.
- the two toothings 54 a and 54 b together form a sagittal toothing.
- the recorder 52 protrudes through the adding input member 54 and into a receptacle of the adder casing 51 , and is slide-guided in the receptacle 51 , such that it is secured against rotating.
- the receptacle is open on a longitudinal side, wherein the opening extends on both sides of the adding input member 54 in its guiding groove.
- Two toothings 52 a and 52 b of the recorder 52 ( FIGS.
- the recorder 52 thus forms the counter toothing 52 a for the toothing 54 a and the counter toothing 52 b for the toothing 54 b .
- the counter toothings 52 a and 52 b are formed as short tooth segments in the circumferential direction, and in the exemplary embodiment exhibit a width of two teeth.
- the counter toothings 52 a and 52 b are shaped to be congruent to the toothings 54 a and 54 b and are offset by half a tooth with respect to each other.
- the counter toothing 52 a passes into toothed engagement with the toothing 54 a and thus rotates the adding input member 54 further by half a tooth.
- the counter toothing 52 b passes into toothed engagement with the toothing 54 b , such that the adding input member 54 is again rotated further by half a tooth.
- the forward and reverse movement together forms the recording movement of the recorder 52 , by which the adding input member 54 is rotated further from an initial rotational angular position to a new rotational angular position.
- the recording movement corresponds to a change of the container 2 . In the next container change, the new position of the previous container change is the initial position.
- the adding input member 54 operates as a first counting member of the adder 50 .
- the recording movement is limited in both directions by corresponding stoppers.
- the stoppers are formed by the adding input member 54 , namely in the maximum toothed engagement of the toothings 52 a and 54 a on the one hand and of the toothings 52 b and 54 b on the other hand. This results in a switching path for the recorder 52 from one of the two end positions to the other, respectively.
- the recorder restoring member 53 presses the recorder 52 into the toothed engagement with the toothing 54 b of the adding input member 54 .
- the switching path is longer than the coupler stroke X.
- the adding input member 54 is coupled to the display structure 56 via an adding intermediate member 55 which is shown individually in FIG. 36 and may in particular also be seen in FIGS. 28, 31 , 33 , 37 and 38 .
- the adding intermediate member 55 is formed by a shaft 55 a and two spur wheels 55 b and 55 c —in the exemplary embodiment, toothed wheels—which are placed rotationally rigid on the shaft 55 a .
- the spur wheel 55 b is an input wheel and the spur wheel 55 c an output wheel of the adding intermediate member 55 .
- the input wheel 55 b co-operates with the adding input member 54 .
- the output wheel 55 c rolls off on a shell inner face of the display structure 56 which thus forms a hollow wheel for the output wheel 55 c .
- the engagement between the output wheel 55 c and the display structure 56 is also formed as a toothed engagement ( FIGS. 29 and 31 ).
- the inner toothing of the display structure 56 does extend over almost the entire circumference of the shell inner area, but is not formed circumferentially but is rather interrupted by a radially raised region.
- FIG. 35 shows the adding input member 54 in a perspective view, in particular onto its shell inner area. It forms an engaging structure 54 c for the input wheel 55 b on the shell inner area. Measured over the entire circumference of the shell inner area, the engaging structure 54 c is very short; in the exemplary embodiment, it exhibits a width, measured in the circumferential direction, of one separation of the toothing of the input wheel 55 b , such that one full revolution of the adding input member 54 rotates the input wheel 55 b and therefore the entire adding intermediate member 55 further by one tooth separation.
- FIGS. 37 and 38 show the adjusting engagement formed between the adding input member 54 and the adding intermediate member 55 by the engaging structure 54 c and the input wheel 55 b , in detail.
- the input wheel 55 b exhibits an even number of teeth comprising first teeth of equal length and second teeth of equal length, which however are axially shorter than the first teeth.
- the first teeth and second teeth are alternately distributed over the circumference. All the teeth of the input wheel 55 b are identical in profile and co-operate in the same way with the engaging structure 54 c .
- the adding input member 54 it may also be noted that it comprises two circular axial portions 54 d and 54 e having different diameters.
- the axially shorter teeth of the input wheel 55 b axially cover only the axial portion 54 d having the greater diameter, while the longer teeth of the input wheel 55 b also extend into the axial portion 54 e having the smaller diameter.
- the engaging structure 54 c is shaped such that the longer teeth may mesh with the engaging structure 54 c in the adjusting engagement, though only in the adjusting engagement.
- the smaller-diameter axial portion 54 e which adjoins the engaging structure 54 c on both sides in the circumferential direction, prevents the adding intermediate member 55 from being able to rotate idly once it has passed through the engaging structure 54 c , by blocking the longer teeth of the input wheel 55 b with the axial portion 54 e having the smaller diameter.
- the functionality of the output means may be seen in particular from an overview of FIGS. 28, 31 and 34 .
- the proximal facing area of the display structure 56 is provided with a colored marking in the form of a colored ring or colored annular portion, and the triggering element 16 comprises a window 16 a axially flush with the colored marking, through which the colored marking may be read.
- the colored marking is colored green over a significant part of its arc length, yellow in an adjoining part and red in a short end part. In the course of the service life, the user thus sees the green part through the window, towards the end of the service life classified as reliable he/she sees the yellow part, and at the end of the service life the red part of the colored marking appears in the window 16 a.
- the adder 50 reduces the recording movement of the recorder 52 to a slow rotational movement of the display structure 56 corresponding to the recorded change in state and composed of discrete rotational increments.
- the recorder 52 performs its back-and-forth recording movement.
- the adding input member 54 is rotated further by one tooth per recording movement.
- the recorder 52 and the adding input member 54 form a first counting and reducing stage.
- a second, next reducing stage is formed by the adding input member 54 and the adding intermediate member 55 , namely by means of the adjusting engagement between the engaging structure 54 c and the input wheel 55 b .
- the adding intermediate member 55 is rotated further by two teeth of its input wheel 55 b for each full revolution of the adding input member 54 .
- the third and final reducing stage is formed by the output wheel 55 c and the display structure 56 .
- the adding input member 54 exhibits a number of teeth in the range of 20 to 30
- the input wheel 55 b exhibits a number of teeth in the range of 6 to 10
- the output wheel 55 c also exhibits a number of teeth in the range of 6 to 10
- the display structure 56 also exhibits a number of teeth in the range of 20 to 30, then the output means 16 , 56 will display the state “end of service life” after at least 120 and at most 750 container changes.
- the piston rod 15 When changing the container 2 , the piston rod 15 is reset to the proximal position shown in FIG. 25 , either manually before connecting the casing parts 1 and 4 or by the piston 3 pressing against the piston rod 15 , while connecting the casing parts 1 and 4 . At the end of the resetting movement, it contacts the recorder 52 and presses it slightly into the adder casing 51 , via its disc 15 a and against the recorder restoring member 53 . This first part of the recording movement should disengage the recorder 52 from the toothing 54 b , in order to prevent the service life timer from counting when the triggering element 16 is merely pressed.
- a priming dosage of a few dosage units for example one to three units, should then be set and the triggering element 16 operated such that the piston rod 15 performs a short priming stroke corresponding to the priming dosage.
- the recorder 52 is initially moved by the coupler stroke X relative to the adding input member 54 , into the toothed engagement with the toothing 54 a and rotates the adding input member 54 further by half a tooth.
- the subsequent priming stroke of the piston rod 15 moves the recorder 52 back by the priming stroke.
- the triggering element 16 When the triggering element 16 is relaxed, it moves even further back relative to the adding input member 54 , by the coupler stroke X, and into engagement with the toothing 54 b , such that the adding input member 54 is rotated further by another half a tooth and the container change is counted.
- the recorder 52 is moved into engagement with the toothing 52 a by abutting against the piston rod 15 situated in the proximal position.
- solely the container change without the triggering movement, alone rotates the adding input member 54 further, at least far enough that when the recorder 52 is relaxed, its toothing 52 b passes into engagement with the toothing 54 b .
- the recorder 52 should not yet pass into a maximum engagement with the toothing 52 a due to the contact with the reset piston rod 15 , in order not to block the coupler movement X after a priming dosage has been set.
- the toothings 52 a and 54 a are embodied correspondingly long in the advancing direction V.
- the adder 50 may be provided in the injection apparatus of the first exemplary embodiment in the same way as has been explained on the basis of the second exemplary embodiment.
- the adder casing 51 merely has to be connected to the triggering element 16 of the first exemplary embodiment in a corresponding way.
- the adder 50 may be inserted in the space remaining free between the stopper element 29 b and the base of the triggering element 28 and may be connected to the triggering element 28 such that it cannot be moved in and counter to the advancing direction V.
- the recorder 52 then protrudes through the stopper element 29 b and is held out of engagement with the toothing 54 b , against the force of the recorder restoring member 53 , by the piston rod 15 situated in the proximal position.
- the switching path of the recorder 52 is also dimensioned such that the full triggering movement moves the recorder 52 into a sufficient toothed engagement with the toothings 52 a and 54 a such that the adding input member 54 is rotated at least far enough that the toothings 52 b and 54 b may then interlock with each other, in order to rotate the adding input member 54 further.
- the toothings 52 b and 54 b do not engage until the piston rod 15 has been advanced slightly away from the drive member 25 .
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Environmental & Geological Engineering (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102004063644A DE102004063644A1 (de) | 2004-12-31 | 2004-12-31 | Vorrichtung zur dosierten Verabreichung eines fluiden Produkts mit Drehfederantrieb |
DE102004063648A DE102004063648A1 (de) | 2004-12-31 | 2004-12-31 | Injektions- oder Infusionsgerät mit Lebensdauer-Ermittlungseinrichtung |
DE102004063647A DE102004063647A1 (de) | 2004-12-31 | 2004-12-31 | Vorrichtung zur dosierten Verabreichung eines fluiden Produkts mit Kupplung |
DE102004063648.6 | 2004-12-31 | ||
DE102004063645A DE102004063645A1 (de) | 2004-12-31 | 2004-12-31 | Vorrichtung zur dosierten Verabreichung eines fluiden Produkts mit Entkopplung für einen Behältniswechsel |
Publications (1)
Publication Number | Publication Date |
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US20060153693A1 true US20060153693A1 (en) | 2006-07-13 |
Family
ID=40491053
Family Applications (7)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/316,208 Abandoned US20060153693A1 (en) | 2004-12-31 | 2005-12-22 | Administering apparatus comprising a service life timer |
US11/769,194 Active 2029-01-14 US8409148B2 (en) | 2004-12-31 | 2007-06-27 | Device for the dosed administration of a fluid product, provided with a coupling |
US11/769,213 Active 2028-01-18 US7951113B2 (en) | 2004-12-31 | 2007-06-27 | Device for the dosed administration of a fluid product comprising a torsion spring drive |
US11/769,496 Expired - Fee Related US7976494B2 (en) | 2004-12-31 | 2007-06-27 | Device for the dosed administration of a fluid product, adapted for the replacement of a container |
US13/178,893 Active 2027-11-14 US9057369B2 (en) | 2004-12-31 | 2011-07-08 | Device for the dosed administration of a fluid product, adapted for the replacement of a container |
US14/735,991 Active 2026-09-23 US10099017B2 (en) | 2004-12-31 | 2015-06-10 | Device for the dosed administration of a fluid product, adapted for the replacement of a container |
US16/127,951 Active 2026-07-02 US11065393B2 (en) | 2004-12-31 | 2018-09-11 | Device for the dosed administration of a fluid product, adapted for the replacement of a container |
Family Applications After (6)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/769,194 Active 2029-01-14 US8409148B2 (en) | 2004-12-31 | 2007-06-27 | Device for the dosed administration of a fluid product, provided with a coupling |
US11/769,213 Active 2028-01-18 US7951113B2 (en) | 2004-12-31 | 2007-06-27 | Device for the dosed administration of a fluid product comprising a torsion spring drive |
US11/769,496 Expired - Fee Related US7976494B2 (en) | 2004-12-31 | 2007-06-27 | Device for the dosed administration of a fluid product, adapted for the replacement of a container |
US13/178,893 Active 2027-11-14 US9057369B2 (en) | 2004-12-31 | 2011-07-08 | Device for the dosed administration of a fluid product, adapted for the replacement of a container |
US14/735,991 Active 2026-09-23 US10099017B2 (en) | 2004-12-31 | 2015-06-10 | Device for the dosed administration of a fluid product, adapted for the replacement of a container |
US16/127,951 Active 2026-07-02 US11065393B2 (en) | 2004-12-31 | 2018-09-11 | Device for the dosed administration of a fluid product, adapted for the replacement of a container |
Country Status (8)
Country | Link |
---|---|
US (7) | US20060153693A1 (fr) |
EP (5) | EP3811992A1 (fr) |
JP (2) | JP4709853B2 (fr) |
CN (3) | CN101094699B (fr) |
AU (3) | AU2005321731B2 (fr) |
DE (4) | DE102004063644A1 (fr) |
PL (1) | PL1833536T3 (fr) |
WO (3) | WO2006069457A1 (fr) |
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2005
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- 2005-11-30 EP EP20208610.4A patent/EP3811992A1/fr active Pending
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- 2005-11-30 WO PCT/CH2005/000713 patent/WO2006069457A1/fr active Application Filing
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- 2005-11-30 CN CN2005800456013A patent/CN101094701B/zh not_active Expired - Fee Related
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- 2005-11-30 EP EP05804308.4A patent/EP1833536B1/fr active Active
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2006
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2007
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2011
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