UA98001C2 - Жидкая лекарственная форма конъюгата полимер-g-csf - Google Patents
Жидкая лекарственная форма конъюгата полимер-g-csf Download PDFInfo
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- UA98001C2 UA98001C2 UAA201003493A UAA201003493A UA98001C2 UA 98001 C2 UA98001 C2 UA 98001C2 UA A201003493 A UAA201003493 A UA A201003493A UA A201003493 A UAA201003493 A UA A201003493A UA 98001 C2 UA98001 C2 UA 98001C2
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
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- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
- C07K17/02—Peptides being immobilised on, or in, an organic carrier
- C07K17/08—Peptides being immobilised on, or in, an organic carrier the carrier being a synthetic polymer
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- Health & Medical Sciences (AREA)
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- General Health & Medical Sciences (AREA)
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- Neurosurgery (AREA)
- Medicinal Preparation (AREA)
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Abstract
Данное изобретение касается жидкой фармацевтической композиции, содержащей полипептид гранулоцитарного колониестимулирующего фактора, конъюгированный с полимером, причем композиция имеет значение рН в диапазоне от 4,5 до 5,5, а натрий присутствует в концентрации 10 ммоль/л.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07115047 | 2007-08-27 | ||
PCT/EP2008/061232 WO2009027437A1 (en) | 2007-08-27 | 2008-08-27 | Liquid formulation of g-csf conjugate |
Publications (1)
Publication Number | Publication Date |
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UA98001C2 true UA98001C2 (ru) | 2012-04-10 |
Family
ID=39862881
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA201003493A UA98001C2 (ru) | 2007-08-27 | 2008-08-27 | Жидкая лекарственная форма конъюгата полимер-g-csf |
Country Status (24)
Country | Link |
---|---|
US (1) | US8546328B2 (ru) |
EP (2) | EP2197919B1 (ru) |
JP (2) | JP5570988B2 (ru) |
KR (1) | KR20100052501A (ru) |
CN (2) | CN101827864A (ru) |
AU (1) | AU2008292186B9 (ru) |
BR (1) | BRPI0815975B8 (ru) |
CA (1) | CA2696594C (ru) |
CY (1) | CY1115908T1 (ru) |
DE (1) | DE202008017456U1 (ru) |
DK (1) | DK2197919T3 (ru) |
EA (1) | EA020069B1 (ru) |
ES (1) | ES2476915T3 (ru) |
HR (1) | HRP20140590T1 (ru) |
IL (1) | IL204190A (ru) |
MX (1) | MX2010002448A (ru) |
NZ (1) | NZ583276A (ru) |
PL (1) | PL2197919T3 (ru) |
PT (1) | PT2197919E (ru) |
RS (1) | RS53404B (ru) |
SI (1) | SI2197919T1 (ru) |
UA (1) | UA98001C2 (ru) |
WO (1) | WO2009027437A1 (ru) |
ZA (1) | ZA201000798B (ru) |
Families Citing this family (8)
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JP5657698B2 (ja) * | 2010-01-19 | 2015-01-21 | ハンミ サイエンス カンパニー リミテッドHanmi Scienceco.,Ltd. | 持続型顆粒球コロニー刺激因子結合体の液剤 |
BR112012022518A2 (pt) | 2010-03-17 | 2020-10-13 | Biogenerix Gmbh | método para obtenção de g- csf recombinante humano biologicamente ativo |
EP2384759A1 (en) | 2010-05-06 | 2011-11-09 | Suomen Punainen Risti Veripalvelu | Sulphated hyaluronic acid in combination with G-CSF for use in mobilising blood stem cells |
TWI751154B (zh) * | 2016-04-18 | 2022-01-01 | 大陸商江蘇恆瑞醫藥股份有限公司 | 一種重組人粒細胞集落刺激因子的製備方法 |
IT201700108526A1 (it) * | 2017-09-28 | 2019-03-28 | Alfasigma Spa | Composizioni orali per il trattamento del refluso gastroesofageo. |
EA202092623A1 (ru) * | 2018-05-04 | 2021-02-01 | Илькоген Илач Санайи Ве Тиджарет А.Ш. | СТАБИЛЬНЫЙ СОСТАВ НА ОСНОВЕ G-CSF, СЛИТОГО С ГИБРИДНЫМ Fc |
CN114224853B (zh) * | 2022-01-04 | 2022-09-23 | 山东新时代药业有限公司 | 聚乙二醇化重组人粒细胞刺激因子注射用冻干制剂 |
TW202417034A (zh) * | 2022-08-19 | 2024-05-01 | 大陸商億一生物醫藥開發(上海)有限公司 | 包含g—csf之調配物及其用途 |
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- 2008-08-27 BR BRPI0815975A patent/BRPI0815975B8/pt not_active IP Right Cessation
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- 2008-08-27 CN CN200880104971A patent/CN101827864A/zh active Pending
- 2008-08-27 RS RS20140361A patent/RS53404B/en unknown
- 2008-08-27 WO PCT/EP2008/061232 patent/WO2009027437A1/en active Application Filing
- 2008-08-27 ES ES08787525.8T patent/ES2476915T3/es active Active
- 2008-08-27 DK DK08787525.8T patent/DK2197919T3/da active
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- 2008-08-27 UA UAA201003493A patent/UA98001C2/ru unknown
- 2008-08-27 DE DE202008017456U patent/DE202008017456U1/de not_active Expired - Lifetime
- 2008-08-27 SI SI200831235T patent/SI2197919T1/sl unknown
- 2008-08-27 EP EP12194213.0A patent/EP2578235A3/en not_active Withdrawn
- 2008-08-27 CN CN201510065114.9A patent/CN104689333B/zh not_active Expired - Fee Related
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- 2014-06-24 HR HRP20140590AT patent/HRP20140590T1/hr unknown
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