DK2197919T3 - Flydende formulering af g-csf-konjugat - Google Patents

Flydende formulering af g-csf-konjugat

Info

Publication number
DK2197919T3
DK2197919T3 DK08787525.8T DK08787525T DK2197919T3 DK 2197919 T3 DK2197919 T3 DK 2197919T3 DK 08787525 T DK08787525 T DK 08787525T DK 2197919 T3 DK2197919 T3 DK 2197919T3
Authority
DK
Denmark
Prior art keywords
liquid formulation
csf conjugate
csf
conjugate
formulation
Prior art date
Application number
DK08787525.8T
Other languages
English (en)
Inventor
Walter Hinderer
Christian Scheckermann
Original Assignee
Ratiopharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ratiopharm Gmbh filed Critical Ratiopharm Gmbh
Application granted granted Critical
Publication of DK2197919T3 publication Critical patent/DK2197919T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • C07K17/08—Peptides being immobilised on, or in, an organic carrier the carrier being a synthetic polymer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK08787525.8T 2007-08-27 2008-08-27 Flydende formulering af g-csf-konjugat DK2197919T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07115047 2007-08-27
PCT/EP2008/061232 WO2009027437A1 (en) 2007-08-27 2008-08-27 Liquid formulation of g-csf conjugate

Publications (1)

Publication Number Publication Date
DK2197919T3 true DK2197919T3 (da) 2014-07-07

Family

ID=39862881

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08787525.8T DK2197919T3 (da) 2007-08-27 2008-08-27 Flydende formulering af g-csf-konjugat

Country Status (24)

Country Link
US (1) US8546328B2 (da)
EP (2) EP2578235A3 (da)
JP (2) JP5570988B2 (da)
KR (1) KR20100052501A (da)
CN (2) CN104689333B (da)
AU (1) AU2008292186B9 (da)
BR (1) BRPI0815975B8 (da)
CA (1) CA2696594C (da)
CY (1) CY1115908T1 (da)
DE (1) DE202008017456U1 (da)
DK (1) DK2197919T3 (da)
EA (1) EA020069B1 (da)
ES (1) ES2476915T3 (da)
HR (1) HRP20140590T1 (da)
IL (1) IL204190A (da)
MX (1) MX2010002448A (da)
NZ (1) NZ583276A (da)
PL (1) PL2197919T3 (da)
PT (1) PT2197919E (da)
RS (1) RS53404B (da)
SI (1) SI2197919T1 (da)
UA (1) UA98001C2 (da)
WO (1) WO2009027437A1 (da)
ZA (1) ZA201000798B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101340710B1 (ko) * 2010-01-19 2013-12-12 한미사이언스 주식회사 지속형 과립구 콜로니 자극인자 결합체의 액상 제제
NZ601759A (en) 2010-03-17 2013-07-26 Biogenerix Gmbh Method for obtaining biologically active recombinant human g-csf
EP2384759A1 (en) 2010-05-06 2011-11-09 Suomen Punainen Risti Veripalvelu Sulphated hyaluronic acid in combination with G-CSF for use in mobilising blood stem cells
CN108368512B (zh) * 2016-04-18 2020-03-27 江苏恒瑞医药股份有限公司 一种重组人粒细胞集落刺激因子的制备方法
IT201700108526A1 (it) * 2017-09-28 2019-03-28 Alfasigma Spa Composizioni orali per il trattamento del refluso gastroesofageo.
EA202092623A1 (ru) * 2018-05-04 2021-02-01 Илькоген Илач Санайи Ве Тиджарет А.Ш. СТАБИЛЬНЫЙ СОСТАВ НА ОСНОВЕ G-CSF, СЛИТОГО С ГИБРИДНЫМ Fc
CN114224853B (zh) * 2022-01-04 2022-09-23 山东新时代药业有限公司 聚乙二醇化重组人粒细胞刺激因子注射用冻干制剂
WO2024037633A2 (en) * 2022-08-19 2024-02-22 Evive Biotechnology (Shanghai) Ltd Formulations comprising g-csf and uses thereof

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Also Published As

Publication number Publication date
RS53404B (en) 2014-10-31
ZA201000798B (en) 2010-10-27
EP2197919B1 (en) 2014-04-09
CN104689333A (zh) 2015-06-10
AU2008292186A1 (en) 2009-03-05
NZ583276A (en) 2012-06-29
SI2197919T1 (sl) 2014-09-30
JP5570988B2 (ja) 2014-08-13
EP2197919A1 (en) 2010-06-23
EP2578235A2 (en) 2013-04-10
DE202008017456U1 (de) 2009-08-27
BRPI0815975B8 (pt) 2021-05-25
CN101827864A (zh) 2010-09-08
AU2008292186B9 (en) 2014-07-03
BRPI0815975A2 (pt) 2015-02-18
AU2008292186B2 (en) 2014-02-27
JP2014101362A (ja) 2014-06-05
KR20100052501A (ko) 2010-05-19
EA020069B1 (ru) 2014-08-29
CY1115908T1 (el) 2017-01-25
JP2010536929A (ja) 2010-12-02
PT2197919E (pt) 2014-07-17
CA2696594A1 (en) 2009-03-05
IL204190A (en) 2015-01-29
JP5836351B2 (ja) 2015-12-24
ES2476915T3 (es) 2014-07-15
EP2578235A3 (en) 2013-08-28
EA201070315A1 (ru) 2010-08-30
WO2009027437A1 (en) 2009-03-05
MX2010002448A (es) 2010-10-04
PL2197919T3 (pl) 2014-09-30
CA2696594C (en) 2019-03-19
HRP20140590T1 (hr) 2014-08-15
US20110053844A1 (en) 2011-03-03
CN104689333B (zh) 2018-05-29
UA98001C2 (uk) 2012-04-10
BRPI0815975B1 (pt) 2019-04-02
US8546328B2 (en) 2013-10-01

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