UA92833C2 - Pyrazole analogues - Google Patents

Pyrazole analogues

Info

Publication number
UA92833C2
UA92833C2 UAA200903927A UAA200903927A UA92833C2 UA 92833 C2 UA92833 C2 UA 92833C2 UA A200903927 A UAA200903927 A UA A200903927A UA A200903927 A UAA200903927 A UA A200903927A UA 92833 C2 UA92833 C2 UA 92833C2
Authority
UA
Ukraine
Prior art keywords
compounds
disorders
preparation
conditions
pyrazole analogues
Prior art date
Application number
UAA200903927A
Other languages
English (en)
Ukrainian (uk)
Inventor
Меттью Дж. Грането
Тодд Майкл Меддакс
Джейме Л. Месферер
Original Assignee
Пфайзер Продактс Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пфайзер Продактс Инк. filed Critical Пфайзер Продактс Инк.
Publication of UA92833C2 publication Critical patent/UA92833C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Изобретение касается соединений формулы (И):(I)или ее фармацевтически приемлемой соли и сольвата, где R- F или Н, способов их получения, промежуточных соединений, применение в приготавлении композиций.Соединения согласно заявленному изобретению являются полезными в лечении многочисленных болезней, расстройств и состояний, в частности аллергических и респираторных болезней, расстройств и состояний.
UAA200903927A 2006-11-27 2007-11-14 Pyrazole analogues UA92833C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86733706P 2006-11-27 2006-11-27

Publications (1)

Publication Number Publication Date
UA92833C2 true UA92833C2 (en) 2010-12-10

Family

ID=39226772

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200903927A UA92833C2 (en) 2006-11-27 2007-11-14 Pyrazole analogues

Country Status (32)

Country Link
US (1) US7772269B2 (ru)
EP (1) EP2097407A1 (ru)
JP (1) JP4469924B2 (ru)
KR (1) KR20090074264A (ru)
CN (1) CN101541790A (ru)
AP (1) AP2009004849A0 (ru)
AR (1) AR063924A1 (ru)
AU (1) AU2007327004A1 (ru)
BR (1) BRPI0718672A2 (ru)
CA (1) CA2667566C (ru)
CL (1) CL2007003403A1 (ru)
CO (1) CO6180447A2 (ru)
CR (1) CR10745A (ru)
CU (1) CU23801B7 (ru)
DO (1) DOP2009000121A (ru)
EA (1) EA016588B1 (ru)
EC (1) ECSP099328A (ru)
GE (1) GEP20125386B (ru)
GT (1) GT200700104A (ru)
HN (1) HN2007000505A (ru)
IL (1) IL198412A0 (ru)
MA (1) MA30924B1 (ru)
MX (1) MX2009005526A (ru)
NO (1) NO20092413L (ru)
NZ (1) NZ576376A (ru)
PE (1) PE20081299A1 (ru)
RS (1) RS20090211A (ru)
TN (1) TN2009000205A1 (ru)
TW (1) TW200831495A (ru)
UA (1) UA92833C2 (ru)
UY (1) UY30743A1 (ru)
WO (1) WO2008065493A1 (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4718650B2 (ja) 2007-11-26 2011-07-06 ファイザー・インク ５−ｌｏ阻害剤としてのピラゾール誘導体
EP2151450A1 (de) * 2008-07-29 2010-02-10 Sandoz AG Verfahren zur Aufarbeitung von mikrobiologisch hergestellten zyklischen Oligopeptiden
WO2011137363A1 (en) * 2010-04-30 2011-11-03 Allergan, Inc. Novel treatment for age related macular degeneration and ocular ischemic disease associated with complement activation by targeting 5-lipoxygenase
US8759386B2 (en) * 2011-01-24 2014-06-24 Boehringer Ingelheim International Gmbh Pyrazole compounds as CRTH2 antagonists

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE913866A1 (en) * 1990-11-28 1992-06-03 Ici Plc Aryl derivatives
NZ266541A (en) 1993-06-14 1997-11-24 Pfizer Imidazole derivatives, intermediate compounds and pharmaceutical compositions
SK281577B6 (sk) * 1994-10-18 2001-05-10 Pfizer Inc. Heterocyklické zlúčeniny a farmaceutický prostriedok na ich báze
US5883106A (en) 1994-10-18 1999-03-16 Pfizer Inc. 5-lipoxygenase inhibitors
JP3400392B2 (ja) * 1994-10-18 2003-04-28 ファイザー製薬株式会社 ５−リポキシゲナーゼ阻害剤及び新規医薬組成物
WO1997011079A1 (en) 1995-09-18 1997-03-27 Pfizer Pharmaceuticals Inc. Novel imidazole lipoxygenase inhibitors
US6194585B1 (en) * 1998-12-22 2001-02-27 Pfizer Inc. Process for preparing 5-lipoxygenase inhibitors
JP2001100686A (ja) * 1999-09-28 2001-04-13 Hitachi Kokusai Electric Inc 表示データ取込方法及び比較検査装置
JP2001100682A (ja) * 1999-09-28 2001-04-13 Sanyo Electric Co Ltd サインシステム

Also Published As

Publication number Publication date
UY30743A1 (es) 2008-07-03
AU2007327004A1 (en) 2008-06-05
PE20081299A1 (es) 2008-09-17
JP4469924B2 (ja) 2010-06-02
CR10745A (es) 2009-05-22
GEP20125386B (en) 2012-01-25
CA2667566A1 (en) 2008-06-05
TW200831495A (en) 2008-08-01
ECSP099328A (es) 2009-06-30
NZ576376A (en) 2011-02-25
WO2008065493A1 (en) 2008-06-05
CO6180447A2 (es) 2010-07-19
CA2667566C (en) 2012-01-03
BRPI0718672A2 (pt) 2013-11-26
IL198412A0 (en) 2010-02-17
NO20092413L (no) 2009-07-20
KR20090074264A (ko) 2009-07-06
US20080125474A1 (en) 2008-05-29
DOP2009000121A (es) 2009-06-15
CU23801B7 (es) 2012-03-15
GT200700104A (es) 2011-04-13
EA200970422A1 (ru) 2009-12-30
TN2009000205A1 (fr) 2010-10-18
MX2009005526A (es) 2009-06-05
HN2007000505A (es) 2010-06-09
CU20090083A7 (es) 2011-09-21
AP2009004849A0 (en) 2009-06-30
AR063924A1 (es) 2009-02-25
EP2097407A1 (en) 2009-09-09
RS20090211A (en) 2010-10-31
CL2007003403A1 (es) 2008-07-04
EA016588B1 (ru) 2012-06-29
MA30924B1 (fr) 2009-11-02
CN101541790A (zh) 2009-09-23
JP2010511601A (ja) 2010-04-15
US7772269B2 (en) 2010-08-10

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