UA86284C2 - Способ получения анилинов, применение аммиака в этом способе и способ аминирования - Google Patents
Способ получения анилинов, применение аммиака в этом способе и способ аминирования Download PDFInfo
- Publication number
- UA86284C2 UA86284C2 UAA200707793A UAA200707793A UA86284C2 UA 86284 C2 UA86284 C2 UA 86284C2 UA A200707793 A UAA200707793 A UA A200707793A UA A200707793 A UAA200707793 A UA A200707793A UA 86284 C2 UA86284 C2 UA 86284C2
- Authority
- UA
- Ukraine
- Prior art keywords
- formula
- compounds
- copper
- ammonia
- trans
- Prior art date
Links
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 title abstract description 32
- 238000000034 method Methods 0.000 title abstract description 25
- 229910021529 ammonia Inorganic materials 0.000 title abstract description 16
- 238000005576 amination reaction Methods 0.000 title description 3
- 150000001448 anilines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract description 69
- 238000006243 chemical reaction Methods 0.000 abstract description 18
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 abstract description 12
- 229910052802 copper Inorganic materials 0.000 abstract description 12
- 239000010949 copper Substances 0.000 abstract description 12
- 229910052739 hydrogen Inorganic materials 0.000 abstract description 11
- 239000001257 hydrogen Substances 0.000 abstract description 11
- 238000002360 preparation method Methods 0.000 abstract description 11
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract description 10
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract description 7
- 229910052794 bromium Inorganic materials 0.000 abstract description 7
- 230000003197 catalytic effect Effects 0.000 abstract description 6
- 125000001246 bromo group Chemical group Br* 0.000 abstract description 5
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract description 5
- 229910052801 chlorine Chemical group 0.000 abstract description 2
- 239000000460 chlorine Chemical group 0.000 abstract description 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 30
- 239000000203 mixture Substances 0.000 description 20
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 18
- VMQMZMRVKUZKQL-UHFFFAOYSA-N Cu+ Chemical class [Cu+] VMQMZMRVKUZKQL-UHFFFAOYSA-N 0.000 description 11
- 239000002904 solvent Substances 0.000 description 7
- JPVYNHNXODAKFH-UHFFFAOYSA-N Cu2+ Chemical class [Cu+2] JPVYNHNXODAKFH-UHFFFAOYSA-N 0.000 description 6
- 239000003480 eluent Substances 0.000 description 6
- 238000001704 evaporation Methods 0.000 description 5
- 230000008020 evaporation Effects 0.000 description 5
- 150000001408 amides Chemical class 0.000 description 4
- 239000000417 fungicide Substances 0.000 description 4
- 229910052738 indium Inorganic materials 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- WDYVUKGVKRZQNM-UHFFFAOYSA-N 6-phosphonohexylphosphonic acid Chemical compound OP(O)(=O)CCCCCCP(O)(O)=O WDYVUKGVKRZQNM-UHFFFAOYSA-N 0.000 description 3
- GSGMVZAYOUOQFT-UHFFFAOYSA-N CC(C1)(C2CC2)C1C(C=CC=C1)=C1N Chemical compound CC(C1)(C2CC2)C1C(C=CC=C1)=C1N GSGMVZAYOUOQFT-UHFFFAOYSA-N 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 3
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 3
- 238000004587 chromatography analysis Methods 0.000 description 3
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 description 3
- 239000012074 organic phase Substances 0.000 description 3
- 239000000741 silica gel Substances 0.000 description 3
- 229910002027 silica gel Inorganic materials 0.000 description 3
- 229910052938 sodium sulfate Inorganic materials 0.000 description 3
- 235000011152 sodium sulphate Nutrition 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- WRBFUJVNYHEZAL-UHFFFAOYSA-N 2-(2-cyclopropylcyclopropyl)aniline Chemical compound NC1=CC=CC=C1C1C(C2CC2)C1 WRBFUJVNYHEZAL-UHFFFAOYSA-N 0.000 description 2
- PAYRUJLWNCNPSJ-UHFFFAOYSA-N Aniline Chemical compound NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 description 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 2
- DKGAVHZHDRPRBM-UHFFFAOYSA-N Tert-Butanol Chemical compound CC(C)(C)O DKGAVHZHDRPRBM-UHFFFAOYSA-N 0.000 description 2
- -1 copper(I) compounds Chemical class 0.000 description 2
- 230000000855 fungicidal effect Effects 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 239000012442 inert solvent Substances 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- JFEKQFAEQBOBIU-UHFFFAOYSA-N 1-bromo-2-(2-cyclopropylcyclopropyl)benzene Chemical group BrC1=CC=CC=C1C1C(C2CC2)C1 JFEKQFAEQBOBIU-UHFFFAOYSA-N 0.000 description 1
- ZEWLWECUJRWWJY-UHFFFAOYSA-N 1-bromo-2-[2-(1-methylcyclopropyl)cyclopropyl]benzene Chemical group C1C(C=2C(=CC=CC=2)Br)C1C1(C)CC1 ZEWLWECUJRWWJY-UHFFFAOYSA-N 0.000 description 1
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 description 1
- BDAGIHXWWSANSR-UHFFFAOYSA-N Formic acid Chemical compound OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000003054 catalyst Substances 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 125000001309 chloro group Chemical group Cl* 0.000 description 1
- RFKZUAOAYVHBOY-UHFFFAOYSA-M copper(1+);acetate Chemical compound [Cu+].CC([O-])=O RFKZUAOAYVHBOY-UHFFFAOYSA-M 0.000 description 1
- OPQARKPSCNTWTJ-UHFFFAOYSA-L copper(ii) acetate Chemical compound [Cu+2].CC([O-])=O.CC([O-])=O OPQARKPSCNTWTJ-UHFFFAOYSA-L 0.000 description 1
- 150000005171 halobenzenes Chemical class 0.000 description 1
- 150000002431 hydrogen Chemical class 0.000 description 1
- 239000000543 intermediate Substances 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/04—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups
- C07C209/06—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of halogen atoms
- C07C209/10—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of halogen atoms with formation of amino groups bound to carbon atoms of six-membered aromatic rings or from amines having nitrogen atoms bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C211/44—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring
- C07C211/45—Monoamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
В заявке описан способ получения соединения формулы І, (I)в которой R, Rи Rвсе независимо друг от друга означают водород или метил, реакцией соединения формулы II, (II)в которой R, Rи Rявляются такими, как определено для формулы І, и Х означает бром или хлор, с аммиаком в присутствии каталитического количества, по меньшей мере, одного медьсодержащего соединения.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH20502004 | 2004-12-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA86284C2 true UA86284C2 (ru) | 2009-04-10 |
Family
ID=35735149
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200707793A UA86284C2 (ru) | 2004-12-10 | 2005-08-12 | Способ получения анилинов, применение аммиака в этом способе и способ аминирования |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20090177011A1 (ru) |
| EP (1) | EP1819660A1 (ru) |
| JP (1) | JP2008523012A (ru) |
| KR (1) | KR20070085983A (ru) |
| CN (1) | CN101072746B (ru) |
| AR (1) | AR051991A1 (ru) |
| AU (1) | AU2005313499A1 (ru) |
| BR (1) | BRPI0518964A2 (ru) |
| CA (1) | CA2587554A1 (ru) |
| EA (1) | EA012435B1 (ru) |
| IL (1) | IL183287A0 (ru) |
| MX (1) | MX2007006747A (ru) |
| TW (1) | TW200633953A (ru) |
| UA (1) | UA86284C2 (ru) |
| WO (1) | WO2006061226A1 (ru) |
| ZA (1) | ZA200703940B (ru) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR053137A1 (es) * | 2005-02-21 | 2007-04-25 | Syngenta Participations Ag | Proceso para la preparacion de anilinas |
| AU2006286808B2 (en) * | 2005-08-30 | 2011-02-24 | Syngenta Participations Ag | Process for the production of anilines |
| DE102006033090A1 (de) * | 2006-07-14 | 2008-01-24 | Bayer Cropscience Ag | Verfahren zum Herstellen von Alkylaniliden aus Halogenbenzolderivaten |
| DE102006033092A1 (de) | 2006-07-14 | 2008-01-24 | Bayer Cropscience Ag | Verfahren zum Herstellen von in 1'-Stellung unverzweigten Alkylnitrobenzolen und Alkylanilinen aus Nitrotoluolen |
| JP2010500304A (ja) * | 2006-08-08 | 2010-01-07 | シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト | フェロセニルビホスフィンリガンドを含むパラジウム複合体の存在下での芳香族アミン類の製造方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU661019A1 (ru) * | 1977-04-11 | 1979-05-05 | Белорусский ордена Трудового Красного Знамени научно-исследовательский институт эпидемиологии и микробиологии | Ингибитор вируса бешенства |
| JPS5727133A (en) * | 1980-07-23 | 1982-02-13 | Mitsubishi Gas Chem Co Inc | Recovery of copper catalyst |
| JPS5727134A (en) * | 1980-07-23 | 1982-02-13 | Mitsubishi Gas Chem Co Inc | Method for recovering copper catalyst |
| JPS61143340A (ja) * | 1984-12-18 | 1986-07-01 | Asahi Chem Ind Co Ltd | １，４−ジアミノベンゼンの製法 |
| JPS6267053A (ja) * | 1985-09-19 | 1987-03-26 | Asahi Chem Ind Co Ltd | １，４−ジブロモベンゼンのアミノ化方法 |
| JPH05194330A (ja) * | 1992-01-21 | 1993-08-03 | Toray Ind Inc | ３，５−ジクロルアニリンの製造方法 |
| JP4511191B2 (ja) * | 2002-03-05 | 2010-07-28 | シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト | Ｏ−シクロプロピル−カルボキサニリド及びそれらの殺真菌剤としての使用 |
-
2005
- 2005-08-12 UA UAA200707793A patent/UA86284C2/ru unknown
- 2005-12-08 BR BRPI0518964-0A patent/BRPI0518964A2/pt not_active IP Right Cessation
- 2005-12-08 CA CA002587554A patent/CA2587554A1/en not_active Abandoned
- 2005-12-08 TW TW094143376A patent/TW200633953A/zh unknown
- 2005-12-08 CN CN2005800421847A patent/CN101072746B/zh not_active Expired - Fee Related
- 2005-12-08 KR KR1020077013055A patent/KR20070085983A/ko not_active Application Discontinuation
- 2005-12-08 US US11/720,692 patent/US20090177011A1/en not_active Abandoned
- 2005-12-08 AU AU2005313499A patent/AU2005313499A1/en not_active Abandoned
- 2005-12-08 JP JP2007544821A patent/JP2008523012A/ja active Pending
- 2005-12-08 MX MX2007006747A patent/MX2007006747A/es not_active Application Discontinuation
- 2005-12-08 EA EA200701163A patent/EA012435B1/ru not_active IP Right Cessation
- 2005-12-08 EP EP05815160A patent/EP1819660A1/en not_active Withdrawn
- 2005-12-08 WO PCT/EP2005/013167 patent/WO2006061226A1/en active Application Filing
- 2005-12-09 AR ARP050105157A patent/AR051991A1/es not_active Application Discontinuation
-
2007
- 2007-05-16 ZA ZA200703940A patent/ZA200703940B/xx unknown
- 2007-05-17 IL IL183287A patent/IL183287A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0518964A2 (pt) | 2008-12-16 |
| TW200633953A (en) | 2006-10-01 |
| JP2008523012A (ja) | 2008-07-03 |
| EA012435B1 (ru) | 2009-10-30 |
| CN101072746B (zh) | 2010-05-05 |
| IL183287A0 (en) | 2007-09-20 |
| MX2007006747A (es) | 2007-07-09 |
| AR051991A1 (es) | 2007-02-21 |
| US20090177011A1 (en) | 2009-07-09 |
| WO2006061226A1 (en) | 2006-06-15 |
| CN101072746A (zh) | 2007-11-14 |
| AU2005313499A1 (en) | 2006-06-15 |
| EP1819660A1 (en) | 2007-08-22 |
| ZA200703940B (en) | 2008-09-25 |
| EA200701163A1 (ru) | 2007-12-28 |
| CA2587554A1 (en) | 2006-06-15 |
| KR20070085983A (ko) | 2007-08-27 |
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