UA82420C2 - Pyridazin-3(2h)-one derivatives and their use as pde4 inhibitors - Google Patents

Pyridazin-3(2h)-one derivatives and their use as pde4 inhibitors Download PDF

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Publication number
UA82420C2
UA82420C2 UAA200606338A UAA200606338A UA82420C2 UA 82420 C2 UA82420 C2 UA 82420C2 UA A200606338 A UAA200606338 A UA A200606338A UA A200606338 A UAA200606338 A UA A200606338A UA 82420 C2 UA82420 C2 UA 82420C2
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ethyl
amino
group
mono
optionally substituted
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UAA200606338A
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English (en)
Ukrainian (uk)
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Пьяц Витторио Даль
Искиэрдо Нуриа Агилар
Альберо Мариа Антониа Буил
Рубио Иоланда Гарридо
Мариа Паола Джованнони
Феррер Хорде Грасиа
Амадор Венсеслао Лумерас
Клаудиа Верджелли
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Алмиралл Продесфарма, С.А.
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Publication of UA82420C2 publication Critical patent/UA82420C2/uk

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    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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  • Chemical & Material Sciences (AREA)
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  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyridine Compounds (AREA)

Abstract

Описаны производные пиридазин-3(2Н)-она общей формулы (І)(I),а также способы их получения, фармацевтические композиции, которые содержат указанные соединения, и применение указанных композиций для лечения как ингибиторов фосфодиэстеразы 4.
UAA200606338A 2003-11-10 2004-08-11 Pyridazin-3(2h)-one derivatives and their use as pde4 inhibitors UA82420C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200302613A ES2232306B1 (es) 2003-11-10 2003-11-10 Nuevos derivados de piridazin-3(2h)-ona.
PCT/EP2004/012604 WO2005049581A1 (en) 2003-11-10 2004-11-08 Pyridazin-3 (2h) -one derivatives and their use as pde4 inhibitors

Publications (1)

Publication Number Publication Date
UA82420C2 true UA82420C2 (en) 2008-04-10

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ID=34586123

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Application Number Title Priority Date Filing Date
UAA200606338A UA82420C2 (en) 2003-11-10 2004-08-11 Pyridazin-3(2h)-one derivatives and their use as pde4 inhibitors

Country Status (20)

Country Link
US (1) US7511038B2 (ru)
EP (1) EP1682519A1 (ru)
JP (1) JP2007510689A (ru)
KR (1) KR20070001907A (ru)
CN (1) CN1878759A (ru)
AR (1) AR046445A1 (ru)
AU (1) AU2004291282A1 (ru)
BR (1) BRPI0416212A (ru)
CA (1) CA2545193A1 (ru)
CO (1) CO5690558A2 (ru)
EC (1) ECSP066541A (ru)
ES (1) ES2232306B1 (ru)
IL (1) IL175278A0 (ru)
NO (1) NO20062726L (ru)
PE (1) PE20050490A1 (ru)
RU (1) RU2006120082A (ru)
TW (1) TW200526593A (ru)
UA (1) UA82420C2 (ru)
WO (1) WO2005049581A1 (ru)
ZA (1) ZA200602415B (ru)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
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UY32297A (es) 2008-12-22 2010-05-31 Almirall Sa Sal mesilato de 5-(2-{[6-(2,2-difluoro-2-fenilitoxi) hexil]amino}-1-hidroxietil)-8-hidroxiquinolin-2( 1h)-ona como agonista del receptor b(beta)2 acrenérgico
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ES2232306B1 (es) 2006-08-01
CO5690558A2 (es) 2006-10-31
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US20070197536A1 (en) 2007-08-23
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KR20070001907A (ko) 2007-01-04
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IL175278A0 (en) 2006-09-05
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WO2005049581A1 (en) 2005-06-02
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