UA81470C2 - Fused heterocycles and uses thereof - Google Patents

Info

Publication number

UA81470C2

UA81470C2 UAA200509430A UA2005009430A UA81470C2 UA 81470 C2 UA81470 C2 UA 81470C2 UA A200509430 A UAA200509430 A UA A200509430A UA 2005009430 A UA2005009430 A UA 2005009430A UA 81470 C2 UA81470 C2 UA 81470C2

Authority

UA

Ukraine

Prior art keywords

optionally substituted

methyl

oxo

benzyl

propyl

Prior art date

2003-03-07

Links

• Espacenet
• Global Dossier
• Discuss

• 125000000623 heterocyclic group Chemical group 0.000 title claims description 48
• 238000000034 method Methods 0.000 claims abstract description 160
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• 238000011282 treatment Methods 0.000 claims abstract description 30
• 206010028980 Neoplasm Diseases 0.000 claims abstract description 20
• 201000011510 cancer Diseases 0.000 claims abstract description 14
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• 238000011321 prophylaxis Methods 0.000 claims abstract description 4
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• 150000003839 salts Chemical class 0.000 claims description 57
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• 125000001424 substituent group Chemical group 0.000 claims description 37
• 125000003118 aryl group Chemical group 0.000 claims description 23
• 125000000547 substituted alkyl group Chemical group 0.000 claims description 22
• RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical compound C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 claims description 18
• UHBGYFCCKRAEHA-UHFFFAOYSA-N P-toluamide Chemical compound CC1=CC=C(C(N)=O)C=C1 UHBGYFCCKRAEHA-UHFFFAOYSA-N 0.000 claims description 17
• 125000003107 substituted aryl group Chemical group 0.000 claims description 17
• 125000000217 alkyl group Chemical group 0.000 claims description 15
• 229910052799 carbon Inorganic materials 0.000 claims description 14
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• 125000004426 substituted alkynyl group Chemical group 0.000 claims description 10
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• XXUNIGZDNWWYED-UHFFFAOYSA-N 2-methylbenzamide Chemical compound CC1=CC=CC=C1C(N)=O XXUNIGZDNWWYED-UHFFFAOYSA-N 0.000 claims description 9
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• 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 8
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• 239000012044 organic layer Substances 0.000 description 13
• 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 13
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