UA80258C2 - Methods of treating pulmonary disease - Google Patents
Methods of treating pulmonary disease Download PDFInfo
- Publication number
- UA80258C2 UA80258C2 UA2004042510A UA2004042510A UA80258C2 UA 80258 C2 UA80258 C2 UA 80258C2 UA 2004042510 A UA2004042510 A UA 2004042510A UA 2004042510 A UA2004042510 A UA 2004042510A UA 80258 C2 UA80258 C2 UA 80258C2
- Authority
- UA
- Ukraine
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- group
- pulmonary
- alkyl
- dipropyl
- substituted
- Prior art date
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- 229910052708 sodium Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
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- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
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- 239000007921 spray Substances 0.000 description 1
- 208000024794 sputum Diseases 0.000 description 1
- 210000003802 sputum Anatomy 0.000 description 1
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- 230000036262 stenosis Effects 0.000 description 1
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- 239000008174 sterile solution Substances 0.000 description 1
- 208000008467 subacute bacterial endocarditis Diseases 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
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- 239000004094 surface-active agent Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 230000006794 tachycardia Effects 0.000 description 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 125000006169 tetracyclic group Chemical class 0.000 description 1
- 125000003718 tetrahydrofuranyl group Chemical group 0.000 description 1
- 125000001412 tetrahydropyranyl group Chemical group 0.000 description 1
- 125000003831 tetrazolyl group Chemical group 0.000 description 1
- 125000000335 thiazolyl group Chemical group 0.000 description 1
- 125000001544 thienyl group Chemical group 0.000 description 1
- 125000002813 thiocarbonyl group Chemical group *C(*)=S 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31790801P | 2001-09-06 | 2001-09-06 | |
| PCT/US2002/028580 WO2003022284A1 (en) | 2001-09-06 | 2002-09-06 | Methods of treating pulmonary disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA80258C2 true UA80258C2 (en) | 2007-09-10 |
Family
ID=23235775
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA2004042510A UA80258C2 (en) | 2001-09-06 | 2002-06-09 | Methods of treating pulmonary disease |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20040259889A1 (is) |
| EP (1) | EP1429775A4 (is) |
| JP (2) | JP4388373B2 (is) |
| KR (1) | KR100979738B1 (is) |
| CN (1) | CN1564688A (is) |
| AU (1) | AU2002341618B2 (is) |
| BR (1) | BR0212329A (is) |
| CA (1) | CA2459533A1 (is) |
| EA (1) | EA014684B1 (is) |
| GE (1) | GEP20074132B (is) |
| HU (1) | HUP0401805A3 (is) |
| IL (1) | IL160715A0 (is) |
| IS (1) | IS7163A (is) |
| MX (1) | MXPA04002135A (is) |
| NZ (1) | NZ532083A (is) |
| PL (1) | PL368935A1 (is) |
| UA (1) | UA80258C2 (is) |
| WO (1) | WO2003022284A1 (is) |
| YU (1) | YU20104A (is) |
| ZA (1) | ZA200401765B (is) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS107404A (en) * | 2002-06-12 | 2007-02-05 | Biogen Idec Ma Inc., | Method of treating ischemia perefusion injury using adenosine receptor antagonists |
| US20040229901A1 (en) * | 2003-02-24 | 2004-11-18 | Lauren Otsuki | Method of treatment of disease using an adenosine A1 receptor antagonist |
| MXPA05011371A (es) * | 2003-04-25 | 2005-12-01 | Novacardia Inc | Metodo para mejorar la diuresis en individuos con la funcion renal deteriorada. |
| WO2005009343A2 (en) * | 2003-06-06 | 2005-02-03 | Endacea, Inc. | A1 adenosine receptor antogonists |
| JP2009532479A (ja) * | 2006-04-06 | 2009-09-10 | ノヴァカーディア，インク． | アデノシンａ１受容体アンタゴニストと抗痙攣薬の同時投与 |
| EP2035009A1 (en) * | 2006-06-16 | 2009-03-18 | Novacardia, Inc. | Prolonged improvement of renal function comprising infrequent administration of an aa1ra |
| DE602007010312D1 (de) | 2006-06-23 | 2010-12-16 | Incyte Corp | Purinonderivate als hm74a-agonisten |
| AR061625A1 (es) | 2006-06-23 | 2008-09-10 | Incyte Corp | Derivados de purinona como agonistas de hm74a |
| WO2008121893A1 (en) * | 2007-03-29 | 2008-10-09 | Novacardia, Inc. | Methods of treating heart failure and renal dysfunction in individuals with an adenosine a1 receptor antagonist |
| US20080242684A1 (en) * | 2007-03-29 | 2008-10-02 | Howard Dittrich | Methods of administration of adenosine a1 receptor antagonists |
| WO2009055021A1 (en) * | 2007-10-26 | 2009-04-30 | New York University School Of Medicine | Methods and compositions for treating hepatic diseases |
| US20090228097A1 (en) * | 2008-03-07 | 2009-09-10 | Abbott Cardiovascular Systems Inc. | A1 Adenosine Receptor Antagonist-Coated Implantable Medical Device |
| US20100063071A1 (en) * | 2008-06-13 | 2010-03-11 | Kiesman William F | Therapeutic compositions and related methods of use |
| CN103237548A (zh) * | 2010-06-30 | 2013-08-07 | 吉利德科学股份有限公司 | A2b腺苷受体拮抗剂用于治疗肺高血压的应用 |
| JP2016516708A (ja) * | 2013-03-14 | 2016-06-09 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | ビシクロ［２．２．２］酸のｇｐｒ１２０モジュレーター |
| CN111770926B (zh) | 2018-01-04 | 2023-07-21 | 因佩蒂斯生物科学有限公司 | 三环化合物、组合物及其医药应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5208240A (en) * | 1991-03-12 | 1993-05-04 | Merrell Dow Pharmaceuticals Inc. | 8-substituted purines as selective adenosine receptor agents |
| TW252044B (is) * | 1992-08-10 | 1995-07-21 | Boehringer Ingelheim Kg | |
| US5446046A (en) * | 1993-10-28 | 1995-08-29 | University Of Florida Research Foundation | A1 adenosine receptor agonists and antagonists as diuretics |
| US5504090A (en) * | 1994-03-30 | 1996-04-02 | Trustees Of The University Of Pennsylvania | Compositions and methods for the prevention and treatment of ischemia-reperfusion organ injury |
| ATE226583T1 (de) * | 1996-06-07 | 2002-11-15 | Hoechst Ag | Verwendung von theophyllinderivaten zur behandlung und propylaxe von schockzuständen, neue xanthinverbindungen und verfahren zu deren herstellung |
| GB9723553D0 (en) * | 1997-11-07 | 1998-01-07 | Duff Gordon W | Prediction of the risk of chronic obstructive airway disease |
| ZA9810766B (en) * | 1997-11-28 | 1999-05-25 | Mochida Pharm Co Ltd | Novel compounds having cgmp-pde inhibitory activity |
| WO1999034803A1 (en) * | 1998-01-09 | 1999-07-15 | The Trustees Of The University Of Pennsylvania | Compositions and methods for use in ischemia-reperfusion and endotoxin-related tissue injury |
| EP0970696A1 (en) * | 1998-05-05 | 2000-01-12 | Kyowa Hakko Kogyo Co., Ltd. | Combination of loop diuretics with adenosine A1-receptor antagonists |
| GEP20043303B (en) * | 1999-11-12 | 2004-01-12 | Biogen Idec Inc | Polycycloalkylpurines as Adenosine Receptor Antagonists |
| AU784878B2 (en) * | 1999-12-02 | 2006-07-13 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A1 A2A and A3 receptors and uses thereof |
-
2002
- 2002-06-09 UA UA2004042510A patent/UA80258C2/uk unknown
- 2002-09-06 IL IL16071502A patent/IL160715A0/xx unknown
- 2002-09-06 BR BR0212329-0A patent/BR0212329A/pt not_active IP Right Cessation
- 2002-09-06 JP JP2003526413A patent/JP4388373B2/ja not_active Expired - Lifetime
- 2002-09-06 CN CNA028195264A patent/CN1564688A/zh active Pending
- 2002-09-06 WO PCT/US2002/028580 patent/WO2003022284A1/en active IP Right Grant
- 2002-09-06 US US10/488,573 patent/US20040259889A1/en not_active Abandoned
- 2002-09-06 AU AU2002341618A patent/AU2002341618B2/en not_active Ceased
- 2002-09-06 PL PL02368935A patent/PL368935A1/xx not_active Application Discontinuation
- 2002-09-06 GE GE5528A patent/GEP20074132B/en unknown
- 2002-09-06 HU HU0401805A patent/HUP0401805A3/hu unknown
- 2002-09-06 KR KR1020047003399A patent/KR100979738B1/ko not_active IP Right Cessation
- 2002-09-06 EA EA200400399A patent/EA014684B1/ru not_active IP Right Cessation
- 2002-09-06 NZ NZ532083A patent/NZ532083A/en not_active IP Right Cessation
- 2002-09-06 YU YU20104A patent/YU20104A/sh unknown
- 2002-09-06 MX MXPA04002135A patent/MXPA04002135A/es not_active Application Discontinuation
- 2002-09-06 CA CA002459533A patent/CA2459533A1/en not_active Abandoned
- 2002-09-06 EP EP02775769A patent/EP1429775A4/en not_active Withdrawn
-
2004
- 2004-02-26 IS IS7163A patent/IS7163A/is unknown
- 2004-03-03 ZA ZA200401765A patent/ZA200401765B/en unknown
-
2009
- 2009-06-22 JP JP2009147918A patent/JP2009209156A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL160715A0 (en) | 2004-08-31 |
| CN1564688A (zh) | 2005-01-12 |
| EA014684B1 (ru) | 2010-12-30 |
| KR100979738B1 (ko) | 2010-09-09 |
| AU2002341618B2 (en) | 2008-06-26 |
| HUP0401805A2 (hu) | 2004-12-28 |
| PL368935A1 (en) | 2005-04-04 |
| EP1429775A1 (en) | 2004-06-23 |
| HUP0401805A3 (en) | 2007-05-02 |
| JP2005501915A (ja) | 2005-01-20 |
| US20040259889A1 (en) | 2004-12-23 |
| EA200400399A1 (ru) | 2004-08-26 |
| CA2459533A1 (en) | 2003-03-20 |
| JP2009209156A (ja) | 2009-09-17 |
| MXPA04002135A (es) | 2005-03-07 |
| GEP20074132B (en) | 2007-06-25 |
| BR0212329A (pt) | 2004-09-21 |
| IS7163A (is) | 2004-02-26 |
| EP1429775A4 (en) | 2007-04-11 |
| JP4388373B2 (ja) | 2009-12-24 |
| ZA200401765B (en) | 2005-04-05 |
| YU20104A (sh) | 2006-08-17 |
| WO2003022284A1 (en) | 2003-03-20 |
| KR20040040457A (ko) | 2004-05-12 |
| NZ532083A (en) | 2005-10-28 |
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