UA76934C2 - Reconstructed human anti-hm 1.24 antibody, coding dna, vector, host cell, method for production of reconstructed human antibody, pharmaceutical composition and drug for treating myeloma containing reconstructed human anti-hm 1.24 antibody - Google Patents
Reconstructed human anti-hm 1.24 antibody, coding dna, vector, host cell, method for production of reconstructed human antibody, pharmaceutical composition and drug for treating myeloma containing reconstructed human anti-hm 1.24 antibody Download PDFInfo
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-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/734—Complement-dependent cytotoxicity [CDC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP26475696 | 1996-10-04 | ||
| PCT/JP1997/003553 WO1998014580A1 (fr) | 1996-10-04 | 1997-10-03 | Anticorps anti-hm1.24 humain reconstitue |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA76934C2 true UA76934C2 (en) | 2006-10-16 |
Family
ID=17407753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA99042469A UA76934C2 (en) | 1996-10-04 | 1997-03-10 | Reconstructed human anti-hm 1.24 antibody, coding dna, vector, host cell, method for production of reconstructed human antibody, pharmaceutical composition and drug for treating myeloma containing reconstructed human anti-hm 1.24 antibody |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US6699974B2 (ru) |
| EP (1) | EP0960936B1 (ru) |
| KR (1) | KR100388256B1 (ru) |
| CN (2) | CN1271205C (ru) |
| AT (1) | ATE512224T1 (ru) |
| AU (1) | AU715156B2 (ru) |
| BR (1) | BR9712488A (ru) |
| CA (1) | CA2267072C (ru) |
| CZ (1) | CZ296790B6 (ru) |
| HK (1) | HK1024261A1 (ru) |
| IL (1) | IL129286A0 (ru) |
| NO (1) | NO325178B1 (ru) |
| PL (1) | PL187642B1 (ru) |
| RU (1) | RU2184147C2 (ru) |
| SK (1) | SK44399A3 (ru) |
| TR (1) | TR199900722T2 (ru) |
| TW (1) | TW530064B (ru) |
| UA (1) | UA76934C2 (ru) |
| WO (1) | WO1998014580A1 (ru) |
| ZA (1) | ZA978865B (ru) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998035698A1 (fr) * | 1997-02-12 | 1998-08-20 | Chugai Seiyaku Kabushiki Kaisha | Remedes contre les tumeurs lymphocitaires |
| CA2282631A1 (en) * | 1997-02-28 | 1998-09-03 | Chugai Seiyaku Kabushiki Kaisha | Lymphocyte activation inhibitors |
| WO1999018997A1 (fr) | 1997-10-14 | 1999-04-22 | Chugai Seiyaku Kabushiki Kaisha | Potentialisateur pour anticorps anti-tumeur lymphoide |
| WO1999043703A1 (fr) * | 1998-02-25 | 1999-09-02 | Chugai Seiyaku Kabushiki Kaisha | Technique de dosage immunochimique de l'anticorps anti-hm1.24 |
| WO2000017395A1 (en) | 1998-09-18 | 2000-03-30 | Chugai Seiyaku Kabushiki Kaisha | Method for detecting or measuring plasmocytomas |
| CA2372585A1 (en) * | 1999-05-10 | 2000-11-16 | Chugai Seiyaku Kabushiki Kaisha | Method of culturing cells |
| CN1370076A (zh) | 1999-08-23 | 2002-09-18 | 中外制药株式会社 | Hm1.24抗原的表达增强剂 |
| WO2001077362A1 (fr) * | 2000-04-06 | 2001-10-18 | Chugai Seiyaku Kabushiki Kaisha | Dosage immunologique d'anticorps anti hm1 . 24 |
| WO2002013860A1 (fr) | 2000-08-11 | 2002-02-21 | Chugai Seiyaku Kabushiki Kaisha | Preparations stabilisees contenant un anticorps |
| ATE457318T1 (de) * | 2000-12-28 | 2010-02-15 | Kyowa Hakko Kirin Co Ltd | Gegen das menschliche bst2 antigen gerichteter monoklonaler antikörper |
| US7931897B2 (en) | 2001-02-07 | 2011-04-26 | Chugai Seiyaku Kabushiki Kaisha | Therapeutic agent for hematopoietic tumors |
| WO2002072615A1 (fr) | 2001-03-09 | 2002-09-19 | Chugai Seiyaku Kabushiki Kaisha | Methode de purification de proteines |
| JP2005508838A (ja) * | 2001-03-23 | 2005-04-07 | アフトン コーポレーション | 膵癌の組合せ治療 |
| JP4297689B2 (ja) * | 2001-04-13 | 2009-07-15 | 中外製薬株式会社 | 抗原の発現量を定量する方法 |
| US20090191232A1 (en) * | 2001-05-04 | 2009-07-30 | Gevas Philip C | Combination therapy for the treatment of tumors |
| KR100877176B1 (ko) * | 2001-06-22 | 2009-01-07 | 츄가이 세이야꾸 가부시키가이샤 | 항글리피칸 3항체를 포함하는 세포증식 억제제 |
| CN1525868A (zh) * | 2001-07-09 | 2004-09-01 | 埃弗顿有限公司 | 治疗和预防肝脏、肺脏和食道的癌症和癌症前期症状 |
| JP4364645B2 (ja) | 2002-02-14 | 2009-11-18 | 中外製薬株式会社 | 抗体含有溶液製剤 |
| US20080219974A1 (en) * | 2002-03-01 | 2008-09-11 | Bernett Matthew J | Optimized antibodies that target hm1.24 |
| JP4753578B2 (ja) * | 2002-06-03 | 2011-08-24 | ジェネンテック， インコーポレイテッド | 合成抗体ファージライブラリー |
| US20060058511A1 (en) | 2002-08-27 | 2006-03-16 | Chugai Seiyaku Kabushiki Kaisha | Method for stabilizing protein solution preparation |
| SI1561756T1 (sl) | 2002-09-11 | 2016-02-29 | Chugai Seiyaku Kabushiki Kaisha | Postopek čiščenja proteinov |
| CA2520010C (en) * | 2003-03-28 | 2012-07-10 | Aphton Corporation | Gastrin hormone immunoassays |
| WO2005014651A1 (ja) | 2003-08-11 | 2005-02-17 | Chugai Seiyaku Kabushiki Kaisha | 糖鎖改変抗hm1.24抗体 |
| JP2007501011A (ja) * | 2003-08-01 | 2007-01-25 | ジェネンテック・インコーポレーテッド | 制限多様性配列を有する結合型ポリペプチド |
| US8603481B2 (en) * | 2003-10-10 | 2013-12-10 | Chugai Seiyaku Kabushiki Kaisha | Therapeutic agents for solid tumors |
| LT2380911T (lt) | 2003-11-05 | 2018-07-10 | Roche Glycart Ag | Antigeną surišančios molekulės, pasižyminčios padidintu fc receptoriaus surišimo afiniškumu ir efektoriaus funkcija |
| EP2168986A3 (en) * | 2004-02-19 | 2010-07-28 | Genentech, Inc. | CDR-repaired antibodies |
| AU2005228897B2 (en) * | 2004-03-29 | 2009-12-10 | Cancer Advances, Inc. | Monoclonal antibodies to gastrin hormone |
| CA2580965C (en) | 2004-09-22 | 2014-04-08 | Receptor Biologix, Inc. | Monoclonal antibodies to progastrin |
| AU2012216702B2 (en) * | 2005-08-26 | 2014-12-04 | Roche Glycart Ag | Modified antigen binding molecules with altered cell signaling activity |
| CA2619298C (en) * | 2005-08-26 | 2017-07-04 | Glycart Biotechnology Ag | Modified antigen binding molecules with altered cell signaling activity |
| EP1957531B1 (en) | 2005-11-07 | 2016-04-13 | Genentech, Inc. | Binding polypeptides with diversified and consensus vh/vl hypervariable sequences |
| EP1973951A2 (en) * | 2005-12-02 | 2008-10-01 | Genentech, Inc. | Binding polypeptides with restricted diversity sequences |
| WO2007074880A1 (ja) | 2005-12-28 | 2007-07-05 | Chugai Seiyaku Kabushiki Kaisha | 抗体含有安定化製剤 |
| CA2660795C (en) | 2006-09-18 | 2014-11-18 | Xencor, Inc. | Optimized antibodies that target hm1.24 |
| PE20091174A1 (es) | 2007-12-27 | 2009-08-03 | Chugai Pharmaceutical Co Ltd | Formulacion liquida con contenido de alta concentracion de anticuerpo |
| EP2473531A4 (en) | 2009-09-03 | 2013-05-01 | Merck Sharp & Dohme | ANTI-GITRANT ANTIBODIES |
| TWI609698B (zh) | 2010-01-20 | 2018-01-01 | Chugai Pharmaceutical Co Ltd | 穩定化的含抗體溶液製劑 |
| EP2735315B1 (en) | 2011-07-19 | 2019-10-02 | Chugai Seiyaku Kabushiki Kaisha | Stable protein-containing preparation containing argininamide or valinamide |
| KR101993488B1 (ko) | 2011-09-01 | 2019-06-26 | 추가이 세이야쿠 가부시키가이샤 | 한외여과에 의해 고도로 농축된 항체를 포함하는 조성물의 제조 방법 |
| CA2935143C (en) | 2013-12-27 | 2024-05-07 | Chugai Seiyaku Kabushiki Kaisha | Method for purifying antibody having low isoelectric point |
| JP6858559B2 (ja) | 2014-08-20 | 2021-04-14 | 中外製薬株式会社 | 蛋白質溶液の粘度測定方法 |
| MA40764A (fr) | 2014-09-26 | 2017-08-01 | Chugai Pharmaceutical Co Ltd | Agent thérapeutique induisant une cytotoxicité |
| CN111050789A (zh) | 2017-06-15 | 2020-04-21 | 癌症进展有限公司 | 用于诱导针对肿瘤和癌症的体液免疫和细胞免疫的组合物和方法 |
| CN109748964B (zh) * | 2017-11-01 | 2020-11-17 | 深圳宾德生物技术有限公司 | CD317单链抗体317scFv、其编码序列及制备方法和应用 |
| US11505610B2 (en) | 2018-04-06 | 2022-11-22 | Atyr Pharma, Inc. | Compositions and methods comprising anti-NRP2 antibodies |
| CN112512480A (zh) | 2018-05-21 | 2021-03-16 | 中外制药株式会社 | 被封入玻璃容器的冷冻干燥制剂 |
| EP3805112A4 (en) | 2018-05-28 | 2022-03-09 | Chugai Seiyaku Kabushiki Kaisha | FILLING NOZZLE |
| WO2021067761A1 (en) * | 2019-10-03 | 2021-04-08 | Atyr Pharma, Inc. | Compositions and methods comprising anti-nrp2 antibodies |
| JPWO2023058723A1 (ru) | 2021-10-08 | 2023-04-13 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO873164L (no) * | 1986-07-30 | 1988-02-01 | Teijin Ltd | Muse-humane kimaere antistoffer. |
| US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| GB8928874D0 (en) * | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
| GB9014932D0 (en) * | 1990-07-05 | 1990-08-22 | Celltech Ltd | Recombinant dna product and method |
| DE122009000019I1 (de) | 1991-04-25 | 2009-07-16 | Chugai Seiyaku K K 5 1 | Rekombinierte humane antikörper gegen den humanen interleukin-6 rezeptor |
| IL114909A (en) * | 1994-08-12 | 1999-10-28 | Immunomedics Inc | Immunoconjugates and humanized antibodies specific for b-cell lymphoma and leukemia cells |
| WO1998035698A1 (fr) * | 1997-02-12 | 1998-08-20 | Chugai Seiyaku Kabushiki Kaisha | Remedes contre les tumeurs lymphocitaires |
| US20020034507A1 (en) * | 1997-02-28 | 2002-03-21 | Yasuo Koishihara | Inhibitor of lymphocyte activation |
| WO1999018212A1 (fr) * | 1997-10-03 | 1999-04-15 | Chugai Seiyaku Kabushiki Kaisha | Anticorps humain naturel |
| WO1999018997A1 (fr) * | 1997-10-14 | 1999-04-22 | Chugai Seiyaku Kabushiki Kaisha | Potentialisateur pour anticorps anti-tumeur lymphoide |
| EP2366718A3 (en) * | 2002-06-28 | 2012-05-02 | Domantis Limited | Ligand |
-
1997
- 1997-03-10 UA UA99042469A patent/UA76934C2/uk unknown
- 1997-10-03 TW TW086114474A patent/TW530064B/zh not_active IP Right Cessation
- 1997-10-03 CN CNB971992150A patent/CN1271205C/zh not_active Expired - Fee Related
- 1997-10-03 SK SK443-99A patent/SK44399A3/sk unknown
- 1997-10-03 AU AU43992/97A patent/AU715156B2/en not_active Ceased
- 1997-10-03 PL PL97332742A patent/PL187642B1/pl not_active IP Right Cessation
- 1997-10-03 BR BR9712488-5A patent/BR9712488A/pt not_active Application Discontinuation
- 1997-10-03 CN CNA2005100687876A patent/CN1765928A/zh active Pending
- 1997-10-03 IL IL12928697A patent/IL129286A0/xx not_active IP Right Cessation
- 1997-10-03 KR KR10-1999-7002902A patent/KR100388256B1/ko not_active IP Right Cessation
- 1997-10-03 TR TR1999/00722T patent/TR199900722T2/xx unknown
- 1997-10-03 ZA ZA9708865A patent/ZA978865B/xx unknown
- 1997-10-03 EP EP97942246A patent/EP0960936B1/en not_active Expired - Lifetime
- 1997-10-03 RU RU99109034/13A patent/RU2184147C2/ru not_active IP Right Cessation
- 1997-10-03 CZ CZ0117399A patent/CZ296790B6/cs not_active IP Right Cessation
- 1997-10-03 AT AT97942246T patent/ATE512224T1/de not_active IP Right Cessation
- 1997-10-03 US US09/269,921 patent/US6699974B2/en not_active Expired - Lifetime
- 1997-10-03 WO PCT/JP1997/003553 patent/WO1998014580A1/ja active IP Right Grant
- 1997-10-03 CA CA002267072A patent/CA2267072C/en not_active Expired - Fee Related
-
1999
- 1999-03-31 NO NO19991591A patent/NO325178B1/no unknown
-
2000
- 2000-03-23 HK HK00101791A patent/HK1024261A1/xx not_active IP Right Cessation
-
2002
- 2002-08-13 US US10/218,253 patent/US7892543B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0960936B1 (en) | 2011-06-08 |
| CN1271205C (zh) | 2006-08-23 |
| WO1998014580A1 (fr) | 1998-04-09 |
| US6699974B2 (en) | 2004-03-02 |
| US20030129185A1 (en) | 2003-07-10 |
| NO991591L (no) | 1999-06-01 |
| HK1024261A1 (en) | 2000-10-05 |
| CN1235639A (zh) | 1999-11-17 |
| TW530064B (en) | 2003-05-01 |
| TR199900722T2 (xx) | 1999-12-21 |
| CZ296790B6 (cs) | 2006-06-14 |
| CA2267072C (en) | 2004-11-30 |
| US20030045691A1 (en) | 2003-03-06 |
| PL332742A1 (en) | 1999-10-11 |
| EP0960936A4 (en) | 2005-01-19 |
| ATE512224T1 (de) | 2011-06-15 |
| EP0960936A1 (en) | 1999-12-01 |
| ZA978865B (en) | 1998-04-20 |
| NO991591D0 (no) | 1999-03-31 |
| CA2267072A1 (en) | 1998-04-09 |
| RU2184147C2 (ru) | 2002-06-27 |
| NO325178B1 (no) | 2008-02-11 |
| KR100388256B1 (ko) | 2003-06-19 |
| AU715156B2 (en) | 2000-01-20 |
| CZ117399A3 (cs) | 1999-09-15 |
| PL187642B1 (pl) | 2004-08-31 |
| CN1765928A (zh) | 2006-05-03 |
| KR20000048884A (ko) | 2000-07-25 |
| IL129286A0 (en) | 2000-02-17 |
| US7892543B2 (en) | 2011-02-22 |
| BR9712488A (pt) | 1999-10-19 |
| SK44399A3 (en) | 2000-05-16 |
| AU4399297A (en) | 1998-04-24 |
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