UA76934C2 - Reconstructed human anti-hm 1.24 antibody, coding dna, vector, host cell, method for production of reconstructed human antibody, pharmaceutical composition and drug for treating myeloma containing reconstructed human anti-hm 1.24 antibody - Google Patents
Reconstructed human anti-hm 1.24 antibody, coding dna, vector, host cell, method for production of reconstructed human antibody, pharmaceutical composition and drug for treating myeloma containing reconstructed human anti-hm 1.24 antibody Download PDFInfo
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-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/734—Complement-dependent cytotoxicity [CDC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP26475696 | 1996-10-04 | ||
| PCT/JP1997/003553 WO1998014580A1 (fr) | 1996-10-04 | 1997-10-03 | Anticorps anti-hm1.24 humain reconstitue |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA76934C2 true UA76934C2 (en) | 2006-10-16 |
Family
ID=17407753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA99042469A UA76934C2 (en) | 1996-10-04 | 1997-03-10 | Reconstructed human anti-hm 1.24 antibody, coding dna, vector, host cell, method for production of reconstructed human antibody, pharmaceutical composition and drug for treating myeloma containing reconstructed human anti-hm 1.24 antibody |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US6699974B2 (cs) |
| EP (1) | EP0960936B1 (cs) |
| KR (1) | KR100388256B1 (cs) |
| CN (2) | CN1271205C (cs) |
| AT (1) | ATE512224T1 (cs) |
| AU (1) | AU715156B2 (cs) |
| BR (1) | BR9712488A (cs) |
| CA (1) | CA2267072C (cs) |
| CZ (1) | CZ296790B6 (cs) |
| IL (1) | IL129286A0 (cs) |
| NO (1) | NO325178B1 (cs) |
| PL (1) | PL187642B1 (cs) |
| RU (1) | RU2184147C2 (cs) |
| SK (1) | SK44399A3 (cs) |
| TR (1) | TR199900722T2 (cs) |
| TW (1) | TW530064B (cs) |
| UA (1) | UA76934C2 (cs) |
| WO (1) | WO1998014580A1 (cs) |
| ZA (1) | ZA978865B (cs) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0997152B1 (en) | 1997-02-12 | 2005-06-08 | Chugai Seiyaku Kabushiki Kaisha | Antibodies as REMEDIES FOR LYMPHOCYTIC TUMORS (EXCEPT MYELOMA) |
| AU718463B2 (en) * | 1997-02-28 | 2000-04-13 | Chugai Seiyaku Kabushiki Kaisha | Inhibitor of lymphocyte activation |
| CN1326565C (zh) | 1997-10-14 | 2007-07-18 | 中外制药株式会社 | 淋巴细胞肿瘤抗体的增强剂 |
| EP1757941B1 (en) * | 1998-02-25 | 2010-03-31 | Chugai Seiyaku Kabushiki Kaisha | Method for immunochemically assaying anti-hm1.24 antibody |
| CA2343054C (en) | 1998-09-18 | 2007-10-30 | Chugai Seiyaku Kabushiki Kaisha | Method for detection or measurement of plasmacytoma cells |
| ES2241599T3 (es) | 1999-05-10 | 2005-11-01 | Chugai Seiyaku Kabushiki Kaisha | Metodo de cultivo de celulas. |
| WO2001013940A1 (fr) | 1999-08-23 | 2001-03-01 | Chugai Seiyaku Kabushiki Kaisha | Potentialisateurs d'expression de l'antigene hm1.24 |
| AU2001246846A1 (en) * | 2000-04-06 | 2001-10-23 | Chugai Seiyaku Kabushiki Kaisha | Immunoassay of anti-hm1.24 antibody |
| EP1314437B1 (en) | 2000-08-11 | 2014-06-25 | Chugai Seiyaku Kabushiki Kaisha | Stabilized antibody-containing preparations |
| US7592005B2 (en) * | 2000-12-28 | 2009-09-22 | Kirin Beer Kabushiki Kaisha | Monoclonal antibody |
| EP1364657B1 (en) | 2001-02-07 | 2016-12-28 | Chugai Seiyaku Kabushiki Kaisha | Remedies for myelocytic leukemia |
| EP2336149A1 (en) | 2001-03-09 | 2011-06-22 | Chugai Seiyaku Kabushiki Kaisha | Protein purification method |
| US20030091574A1 (en) * | 2001-03-23 | 2003-05-15 | Gevas Philip C. | Combination treatment of pancreatic cancer |
| EP1378752A4 (en) * | 2001-04-13 | 2004-08-04 | Chugai Pharmaceutical Co Ltd | METHOD FOR QUANTIFYING ANTIGEN EXPRESSION |
| US20090191232A1 (en) * | 2001-05-04 | 2009-07-30 | Gevas Philip C | Combination therapy for the treatment of tumors |
| EP1411118B1 (en) * | 2001-06-22 | 2008-09-03 | Chugai Seiyaku Kabushiki Kaisha | Cell proliferation inhibitors containing anti-glypican-3 antibody |
| WO2003005955A2 (en) * | 2001-07-09 | 2003-01-23 | Aphton Corporation | Treatment and prevention of cancerous and pre-cancerous conditions of the liver, lung and esophagus |
| DK1475101T3 (da) * | 2002-02-14 | 2011-01-10 | Chugai Pharmaceutical Co Ltd | Antistof-holdige farmaceutiske opløsninger |
| US20080219974A1 (en) * | 2002-03-01 | 2008-09-11 | Bernett Matthew J | Optimized antibodies that target hm1.24 |
| EP1513879B1 (en) * | 2002-06-03 | 2018-08-22 | Genentech, Inc. | Synthetic antibody phage libraries |
| EP1541165A4 (en) | 2002-08-27 | 2009-06-24 | Chugai Pharmaceutical Co Ltd | METHOD FOR STABILIZING PROTEIN PREPARATION |
| WO2004024752A1 (ja) * | 2002-09-11 | 2004-03-25 | Chugai Seiyaku Kabushiki Kaisha | タンパク質精製方法 |
| CN1781023A (zh) * | 2003-03-28 | 2006-05-31 | 埃弗顿有限公司 | 胃泌素激素免疫测定 |
| AU2004261980A1 (en) * | 2003-08-01 | 2005-02-10 | Genentech, Inc. | Antibody CDR polypeptide sequences with restricted diversity |
| JPWO2005014651A1 (ja) * | 2003-08-11 | 2006-11-24 | 中外製薬株式会社 | 糖鎖改変抗ｈｍ１．２４抗体 |
| EP1693069B1 (en) * | 2003-10-10 | 2013-07-24 | Chugai Seiyaku Kabushiki Kaisha | Remedy for solid tumor |
| HRP20100303T1 (hr) * | 2003-11-05 | 2010-07-31 | Roche Glycart Ag | Cd20 antitijela s povećanim afinitetom vezivanja fc receptora i efektorskim djelovanjem |
| EP2168986A3 (en) * | 2004-02-19 | 2010-07-28 | Genentech, Inc. | CDR-repaired antibodies |
| JP5576592B2 (ja) * | 2004-03-29 | 2014-08-20 | キャンサー アドヴァンシズ インコーポレイテッド | ガストリンホルモンに対するモノクローナル抗体 |
| CN101048659B (zh) | 2004-09-22 | 2013-03-13 | 受体生物技术公司 | 抗前胃泌素单克隆抗体 |
| AU2006290433B2 (en) * | 2005-08-26 | 2012-06-07 | Roche Glycart Ag | Modified antigen binding molecules with altered cell signaling activity |
| AU2012216702B2 (en) * | 2005-08-26 | 2014-12-04 | Roche Glycart Ag | Modified antigen binding molecules with altered cell signaling activity |
| ES2577292T3 (es) | 2005-11-07 | 2016-07-14 | Genentech, Inc. | Polipéptidos de unión con secuencias hipervariables de VH/VL diversificadas y consenso |
| EP1973951A2 (en) * | 2005-12-02 | 2008-10-01 | Genentech, Inc. | Binding polypeptides with restricted diversity sequences |
| JP5231810B2 (ja) | 2005-12-28 | 2013-07-10 | 中外製薬株式会社 | 抗体含有安定化製剤 |
| CA2660795C (en) * | 2006-09-18 | 2014-11-18 | Xencor, Inc. | Optimized antibodies that target hm1.24 |
| PE20091174A1 (es) | 2007-12-27 | 2009-08-03 | Chugai Pharmaceutical Co Ltd | Formulacion liquida con contenido de alta concentracion de anticuerpo |
| EP3023438B1 (en) * | 2009-09-03 | 2020-03-11 | Merck Sharp & Dohme Corp. | Anti-gitr antibodies |
| AR080428A1 (es) | 2010-01-20 | 2012-04-11 | Chugai Pharmaceutical Co Ltd | Formulaciones liquidas estabilizadas contentivas de anticuerpos |
| JP6176849B2 (ja) | 2011-07-19 | 2017-08-09 | 中外製薬株式会社 | アルギニンアミドまたはその類似化合物を含む安定なタンパク質含有製剤 |
| RU2638859C9 (ru) | 2011-09-01 | 2018-01-31 | Чугаи Сейяку Кабусики Кайся | Способ получения композиции, включающей высококонцентрированные антитела, путем ультрафильтрации |
| CA2935143C (en) | 2013-12-27 | 2024-05-07 | Chugai Seiyaku Kabushiki Kaisha | Method for purifying antibody having low isoelectric point |
| WO2016027859A1 (ja) | 2014-08-20 | 2016-02-25 | 中外製薬株式会社 | 蛋白質溶液の粘度測定方法 |
| MA40764A (fr) | 2014-09-26 | 2017-08-01 | Chugai Pharmaceutical Co Ltd | Agent thérapeutique induisant une cytotoxicité |
| US12150978B2 (en) | 2017-06-15 | 2024-11-26 | Cancer Advances Inc. | Compositions and methods for preventing tumors and cancer |
| WO2018232230A1 (en) | 2017-06-15 | 2018-12-20 | Cancer Advances Inc. | Compositions and methods for inducing humoral and cellular immunities against tumors and cancer |
| CN109748964B (zh) * | 2017-11-01 | 2020-11-17 | 深圳宾德生物技术有限公司 | CD317单链抗体317scFv、其编码序列及制备方法和应用 |
| US11505610B2 (en) | 2018-04-06 | 2022-11-22 | Atyr Pharma, Inc. | Compositions and methods comprising anti-NRP2 antibodies |
| TWI840360B (zh) | 2018-05-21 | 2024-05-01 | 日商中外製藥股份有限公司 | 密封於玻璃容器之凍結乾燥的製劑、套組、製造凍結乾燥製劑的方法、防止或減低凍結乾燥製劑的玻璃容器成霧的方法、及容器內面經過硫酸銨處理或ｖｉｓｔ處理之玻璃容器 |
| CN115636142A (zh) | 2018-05-28 | 2023-01-24 | 中外制药株式会社 | 填充喷嘴 |
| JP7701913B2 (ja) | 2019-10-03 | 2025-07-02 | エータイアー ファーマ， インコーポレイテッド | 抗ｎｒｐ２抗体を含む組成物および方法 |
| WO2023058723A1 (ja) | 2021-10-08 | 2023-04-13 | 中外製薬株式会社 | プレフィルドシリンジ製剤の調製方法 |
| JP7544986B2 (ja) | 2022-04-26 | 2024-09-03 | 中外製薬株式会社 | 医薬製剤含有フィルター内蔵シリンジ |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO873164L (no) * | 1986-07-30 | 1988-02-01 | Teijin Ltd | Muse-humane kimaere antistoffer. |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| GB8928874D0 (en) * | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
| GB9014932D0 (en) * | 1990-07-05 | 1990-08-22 | Celltech Ltd | Recombinant dna product and method |
| HU218140B (hu) | 1991-04-25 | 2000-06-28 | Chugai Seiyaku Kabushiki Kaisha | Humán interleukin-6-receptorral szembeni átalakított humán antitest |
| CA2195557C (en) * | 1994-08-12 | 2006-10-17 | Shui-On Leung | Immunoconjugates and humanized antibodies specific for b-cell lymphoma and leukemia cells |
| EP0997152B1 (en) * | 1997-02-12 | 2005-06-08 | Chugai Seiyaku Kabushiki Kaisha | Antibodies as REMEDIES FOR LYMPHOCYTIC TUMORS (EXCEPT MYELOMA) |
| US20020034507A1 (en) * | 1997-02-28 | 2002-03-21 | Yasuo Koishihara | Inhibitor of lymphocyte activation |
| BR9812846A (pt) * | 1997-10-03 | 2000-08-08 | Chugai Pharmaceutical Co Ltd | Anticorpo humanizado natural |
| CN1326565C (zh) * | 1997-10-14 | 2007-07-18 | 中外制药株式会社 | 淋巴细胞肿瘤抗体的增强剂 |
| JP2006512895A (ja) * | 2002-06-28 | 2006-04-20 | ドマンティス リミテッド | リガンド |
-
1997
- 1997-03-10 UA UA99042469A patent/UA76934C2/uk unknown
- 1997-10-03 SK SK443-99A patent/SK44399A3/sk unknown
- 1997-10-03 WO PCT/JP1997/003553 patent/WO1998014580A1/ja active IP Right Grant
- 1997-10-03 TR TR1999/00722T patent/TR199900722T2/xx unknown
- 1997-10-03 TW TW086114474A patent/TW530064B/zh not_active IP Right Cessation
- 1997-10-03 EP EP97942246A patent/EP0960936B1/en not_active Expired - Lifetime
- 1997-10-03 PL PL97332742A patent/PL187642B1/pl not_active IP Right Cessation
- 1997-10-03 AU AU43992/97A patent/AU715156B2/en not_active Ceased
- 1997-10-03 IL IL12928697A patent/IL129286A0/xx not_active IP Right Cessation
- 1997-10-03 ZA ZA9708865A patent/ZA978865B/xx unknown
- 1997-10-03 BR BR9712488-5A patent/BR9712488A/pt not_active Application Discontinuation
- 1997-10-03 AT AT97942246T patent/ATE512224T1/de not_active IP Right Cessation
- 1997-10-03 RU RU99109034/13A patent/RU2184147C2/ru not_active IP Right Cessation
- 1997-10-03 CZ CZ0117399A patent/CZ296790B6/cs not_active IP Right Cessation
- 1997-10-03 CN CNB971992150A patent/CN1271205C/zh not_active Expired - Fee Related
- 1997-10-03 CN CNA2005100687876A patent/CN1765928A/zh active Pending
- 1997-10-03 US US09/269,921 patent/US6699974B2/en not_active Expired - Lifetime
- 1997-10-03 CA CA002267072A patent/CA2267072C/en not_active Expired - Fee Related
- 1997-10-03 KR KR10-1999-7002902A patent/KR100388256B1/ko not_active Expired - Fee Related
-
1999
- 1999-03-31 NO NO19991591A patent/NO325178B1/no unknown
-
2002
- 2002-08-13 US US10/218,253 patent/US7892543B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0960936A1 (en) | 1999-12-01 |
| NO991591L (no) | 1999-06-01 |
| IL129286A0 (en) | 2000-02-17 |
| WO1998014580A1 (fr) | 1998-04-09 |
| AU715156B2 (en) | 2000-01-20 |
| EP0960936A4 (en) | 2005-01-19 |
| EP0960936B1 (en) | 2011-06-08 |
| PL332742A1 (en) | 1999-10-11 |
| ATE512224T1 (de) | 2011-06-15 |
| TR199900722T2 (xx) | 1999-12-21 |
| SK44399A3 (en) | 2000-05-16 |
| US6699974B2 (en) | 2004-03-02 |
| CN1235639A (zh) | 1999-11-17 |
| CN1765928A (zh) | 2006-05-03 |
| US20030045691A1 (en) | 2003-03-06 |
| PL187642B1 (pl) | 2004-08-31 |
| NO325178B1 (no) | 2008-02-11 |
| KR20000048884A (ko) | 2000-07-25 |
| ZA978865B (en) | 1998-04-20 |
| AU4399297A (en) | 1998-04-24 |
| KR100388256B1 (ko) | 2003-06-19 |
| US20030129185A1 (en) | 2003-07-10 |
| NO991591D0 (no) | 1999-03-31 |
| US7892543B2 (en) | 2011-02-22 |
| BR9712488A (pt) | 1999-10-19 |
| HK1024261A1 (en) | 2000-10-05 |
| RU2184147C2 (ru) | 2002-06-27 |
| CZ117399A3 (cs) | 1999-09-15 |
| CA2267072C (en) | 2004-11-30 |
| CA2267072A1 (en) | 1998-04-09 |
| CN1271205C (zh) | 2006-08-23 |
| CZ296790B6 (cs) | 2006-06-14 |
| TW530064B (en) | 2003-05-01 |
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