UA76934C2 - Reconstructed human anti-hm 1.24 antibody, coding dna, vector, host cell, method for production of reconstructed human antibody, pharmaceutical composition and drug for treating myeloma containing reconstructed human anti-hm 1.24 antibody - Google Patents
Reconstructed human anti-hm 1.24 antibody, coding dna, vector, host cell, method for production of reconstructed human antibody, pharmaceutical composition and drug for treating myeloma containing reconstructed human anti-hm 1.24 antibody Download PDFInfo
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-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/734—Complement-dependent cytotoxicity [CDC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP26475696 | 1996-10-04 | ||
| PCT/JP1997/003553 WO1998014580A1 (fr) | 1996-10-04 | 1997-10-03 | Anticorps anti-hm1.24 humain reconstitue |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA76934C2 true UA76934C2 (en) | 2006-10-16 |
Family
ID=17407753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA99042469A UA76934C2 (en) | 1996-10-04 | 1997-03-10 | Reconstructed human anti-hm 1.24 antibody, coding dna, vector, host cell, method for production of reconstructed human antibody, pharmaceutical composition and drug for treating myeloma containing reconstructed human anti-hm 1.24 antibody |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US6699974B2 (cs) |
| EP (1) | EP0960936B1 (cs) |
| KR (1) | KR100388256B1 (cs) |
| CN (2) | CN1271205C (cs) |
| AT (1) | ATE512224T1 (cs) |
| AU (1) | AU715156B2 (cs) |
| BR (1) | BR9712488A (cs) |
| CA (1) | CA2267072C (cs) |
| CZ (1) | CZ296790B6 (cs) |
| IL (1) | IL129286A0 (cs) |
| NO (1) | NO325178B1 (cs) |
| PL (1) | PL187642B1 (cs) |
| RU (1) | RU2184147C2 (cs) |
| SK (1) | SK44399A3 (cs) |
| TR (1) | TR199900722T2 (cs) |
| TW (1) | TW530064B (cs) |
| UA (1) | UA76934C2 (cs) |
| WO (1) | WO1998014580A1 (cs) |
| ZA (1) | ZA978865B (cs) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100655979B1 (ko) | 1997-02-12 | 2006-12-08 | 츄가이 세이야꾸 가부시키가이샤 | 임파구계 종양의 치료제 |
| CA2282631A1 (en) * | 1997-02-28 | 1998-09-03 | Chugai Seiyaku Kabushiki Kaisha | Lymphocyte activation inhibitors |
| KR100362974B1 (ko) * | 1997-10-14 | 2002-11-30 | 츄가이 세이야꾸 가부시키가이샤 | 림프구계 종양에 대한 항체의 증진제 |
| EP1757941B1 (en) * | 1998-02-25 | 2010-03-31 | Chugai Seiyaku Kabushiki Kaisha | Method for immunochemically assaying anti-hm1.24 antibody |
| US6602663B1 (en) | 1998-09-18 | 2003-08-05 | Chugai Seiyaku Kabushiki Kaisha | Method for detection or measuring plasmocytoma cells |
| US6900052B1 (en) | 1999-05-10 | 2005-05-31 | Chugai Seiyaku Kabushiki Kaisha | Method of culturing cells |
| TWI290832B (en) | 1999-08-23 | 2007-12-11 | Chugai Pharmaceutical Co Ltd | Expression enhancer for HM1.24 antigen |
| AU2001246846A1 (en) * | 2000-04-06 | 2001-10-23 | Chugai Seiyaku Kabushiki Kaisha | Immunoassay of anti-hm1.24 antibody |
| EP2311492B1 (en) | 2000-08-11 | 2017-10-04 | Chugai Seiyaku Kabushiki Kaisha | Antibody-containing stabilized preparations |
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| EP2208784B1 (en) * | 2001-06-22 | 2013-01-02 | Chugai Seiyaku Kabushiki Kaisha | Cell proliferation inhibitors containing anti-glypican 3 antibody |
| US20030021786A1 (en) * | 2001-07-09 | 2003-01-30 | Gevas Philip C. | Treatment and prevention of cancerous and pre-cancerous conditions of the liver, lung and esophagus |
| DK1475101T3 (da) * | 2002-02-14 | 2011-01-10 | Chugai Pharmaceutical Co Ltd | Antistof-holdige farmaceutiske opløsninger |
| US20080219974A1 (en) * | 2002-03-01 | 2008-09-11 | Bernett Matthew J | Optimized antibodies that target hm1.24 |
| JP4753578B2 (ja) * | 2002-06-03 | 2011-08-24 | ジェネンテック， インコーポレイテッド | 合成抗体ファージライブラリー |
| US20060058511A1 (en) | 2002-08-27 | 2006-03-16 | Chugai Seiyaku Kabushiki Kaisha | Method for stabilizing protein solution preparation |
| EP1561756B1 (en) | 2002-09-11 | 2015-12-23 | Chugai Seiyaku Kabushiki Kaisha | Method of purifying protein |
| CA2520010C (en) * | 2003-03-28 | 2012-07-10 | Aphton Corporation | Gastrin hormone immunoassays |
| WO2005014651A1 (ja) | 2003-08-11 | 2005-02-17 | Chugai Seiyaku Kabushiki Kaisha | 糖鎖改変抗hm1.24抗体 |
| AU2004261980A1 (en) * | 2003-08-01 | 2005-02-10 | Genentech, Inc. | Antibody CDR polypeptide sequences with restricted diversity |
| US8603481B2 (en) * | 2003-10-10 | 2013-12-10 | Chugai Seiyaku Kabushiki Kaisha | Therapeutic agents for solid tumors |
| KR101364858B1 (ko) * | 2003-11-05 | 2014-02-19 | 로슈 글리카트 아게 | 증가된 ｆｃ 수용체 결합 친화성 및 효과기 기능을 가진 ｃｄ20 항체 |
| DK1716181T3 (da) * | 2004-02-19 | 2010-03-01 | Genentech Inc | CDR-reparerede antistoffer |
| AU2005228897B2 (en) * | 2004-03-29 | 2009-12-10 | Cancer Advances, Inc. | Monoclonal antibodies to gastrin hormone |
| KR101333168B1 (ko) | 2004-09-22 | 2013-11-28 | 리셉터 바이오로직스 인크 | 프로가스트린에 대한 모노클로날 항체 |
| AU2012216702B2 (en) * | 2005-08-26 | 2014-12-04 | Roche Glycart Ag | Modified antigen binding molecules with altered cell signaling activity |
| AR055137A1 (es) * | 2005-08-26 | 2007-08-08 | Glycart Biotechnology Ag | Moleculas de union al antigeno modificadas con actividad de senalizacion celular alterada |
| US8679490B2 (en) | 2005-11-07 | 2014-03-25 | Genentech, Inc. | Binding polypeptides with diversified and consensus VH/VL hypervariable sequences |
| WO2007064919A2 (en) * | 2005-12-02 | 2007-06-07 | Genentech, Inc. | Binding polypeptides with restricted diversity sequences |
| US9084777B2 (en) | 2005-12-28 | 2015-07-21 | Chugai Seiyaku Kabushiki Kaisha | Stabilized antibody-containing formulations |
| CA2660795C (en) | 2006-09-18 | 2014-11-18 | Xencor, Inc. | Optimized antibodies that target hm1.24 |
| PE20091174A1 (es) | 2007-12-27 | 2009-08-03 | Chugai Pharmaceutical Co Ltd | Formulacion liquida con contenido de alta concentracion de anticuerpo |
| HUE049825T2 (hu) | 2009-09-03 | 2020-10-28 | Merck Sharp & Dohme | Anti-GITR antitestek |
| TWI505838B (zh) | 2010-01-20 | 2015-11-01 | Chugai Pharmaceutical Co Ltd | Stabilized antibody solution containing |
| EP2735315B1 (en) | 2011-07-19 | 2019-10-02 | Chugai Seiyaku Kabushiki Kaisha | Stable protein-containing preparation containing argininamide or valinamide |
| EP2750784A1 (en) | 2011-09-01 | 2014-07-09 | Chugai Seiyaku Kabushiki Kaisha | Method for preparing a composition comprising highly concentrated antibodies by ultrafiltration |
| AU2014370873B2 (en) | 2013-12-27 | 2020-06-11 | Chugai Seiyaku Kabushiki Kaisha | Method for purifying antibody having low isoelectric point |
| EP4056993A1 (en) | 2014-08-20 | 2022-09-14 | Chugai Seiyaku Kabushiki Kaisha | Method for measuring viscosity of protein solution |
| MA40764A (fr) | 2014-09-26 | 2017-08-01 | Chugai Pharmaceutical Co Ltd | Agent thérapeutique induisant une cytotoxicité |
| US12150978B2 (en) | 2017-06-15 | 2024-11-26 | Cancer Advances Inc. | Compositions and methods for preventing tumors and cancer |
| JP7469225B2 (ja) | 2017-06-15 | 2024-04-16 | キャンサー アドヴァンシーズ インク． | 腫瘍及び癌に対する体液性及び細胞性免疫を誘発するための組成物及び方法 |
| CN109748964B (zh) * | 2017-11-01 | 2020-11-17 | 深圳宾德生物技术有限公司 | CD317单链抗体317scFv、其编码序列及制备方法和应用 |
| JP2021521110A (ja) | 2018-04-06 | 2021-08-26 | エータイアー ファーマ， インコーポレイテッド | 抗ｎｒｐ２抗体を含む組成物及び方法 |
| TWI840360B (zh) | 2018-05-21 | 2024-05-01 | 日商中外製藥股份有限公司 | 密封於玻璃容器之凍結乾燥的製劑、套組、製造凍結乾燥製劑的方法、防止或減低凍結乾燥製劑的玻璃容器成霧的方法、及容器內面經過硫酸銨處理或ｖｉｓｔ處理之玻璃容器 |
| JP6955098B2 (ja) | 2018-05-28 | 2021-10-27 | 中外製薬株式会社 | 充填ノズル |
| CN114746120B (zh) * | 2019-10-03 | 2024-07-30 | Atyr医药公司 | 包含抗nrp2抗体的组合物和方法 |
| KR20240082388A (ko) | 2021-10-08 | 2024-06-10 | 추가이 세이야쿠 가부시키가이샤 | 프리필드 시린지 제제의 조제 방법 |
| CN119486774A (zh) | 2022-04-26 | 2025-02-18 | 中外制药株式会社 | 含有药物制剂的内置过滤器的注射器 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO873164L (no) * | 1986-07-30 | 1988-02-01 | Teijin Ltd | Muse-humane kimaere antistoffer. |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| GB8928874D0 (en) * | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
| GB9014932D0 (en) * | 1990-07-05 | 1990-08-22 | Celltech Ltd | Recombinant dna product and method |
| TW205553B (cs) | 1991-04-25 | 1993-05-11 | Chugai Pharmaceutical Co Ltd | |
| WO1996004925A1 (en) * | 1994-08-12 | 1996-02-22 | Immunomedics, Inc. | Immunoconjugates and humanized antibodies specific for b-cell lymphoma and leukemia cells |
| KR100655979B1 (ko) * | 1997-02-12 | 2006-12-08 | 츄가이 세이야꾸 가부시키가이샤 | 임파구계 종양의 치료제 |
| US20020034507A1 (en) * | 1997-02-28 | 2002-03-21 | Yasuo Koishihara | Inhibitor of lymphocyte activation |
| ATE373712T1 (de) * | 1997-10-03 | 2007-10-15 | Chugai Pharmaceutical Co Ltd | Natürlicher menschlicher antikörper |
| KR100362974B1 (ko) * | 1997-10-14 | 2002-11-30 | 츄가이 세이야꾸 가부시키가이샤 | 림프구계 종양에 대한 항체의 증진제 |
| CA2492092A1 (en) * | 2002-06-28 | 2004-01-08 | Greg Winter | Immunoglobin single variant antigen-binding domains and dual-specific constructs |
-
1997
- 1997-03-10 UA UA99042469A patent/UA76934C2/uk unknown
- 1997-10-03 PL PL97332742A patent/PL187642B1/pl not_active IP Right Cessation
- 1997-10-03 US US09/269,921 patent/US6699974B2/en not_active Expired - Lifetime
- 1997-10-03 AT AT97942246T patent/ATE512224T1/de not_active IP Right Cessation
- 1997-10-03 CZ CZ0117399A patent/CZ296790B6/cs not_active IP Right Cessation
- 1997-10-03 KR KR10-1999-7002902A patent/KR100388256B1/ko not_active Expired - Fee Related
- 1997-10-03 CN CNB971992150A patent/CN1271205C/zh not_active Expired - Fee Related
- 1997-10-03 TW TW086114474A patent/TW530064B/zh not_active IP Right Cessation
- 1997-10-03 WO PCT/JP1997/003553 patent/WO1998014580A1/ja active IP Right Grant
- 1997-10-03 AU AU43992/97A patent/AU715156B2/en not_active Ceased
- 1997-10-03 BR BR9712488-5A patent/BR9712488A/pt not_active Application Discontinuation
- 1997-10-03 TR TR1999/00722T patent/TR199900722T2/xx unknown
- 1997-10-03 RU RU99109034/13A patent/RU2184147C2/ru not_active IP Right Cessation
- 1997-10-03 IL IL12928697A patent/IL129286A0/xx not_active IP Right Cessation
- 1997-10-03 CA CA002267072A patent/CA2267072C/en not_active Expired - Fee Related
- 1997-10-03 CN CNA2005100687876A patent/CN1765928A/zh active Pending
- 1997-10-03 ZA ZA9708865A patent/ZA978865B/xx unknown
- 1997-10-03 SK SK443-99A patent/SK44399A3/sk unknown
- 1997-10-03 EP EP97942246A patent/EP0960936B1/en not_active Expired - Lifetime
-
1999
- 1999-03-31 NO NO19991591A patent/NO325178B1/no unknown
-
2002
- 2002-08-13 US US10/218,253 patent/US7892543B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| BR9712488A (pt) | 1999-10-19 |
| AU715156B2 (en) | 2000-01-20 |
| EP0960936B1 (en) | 2011-06-08 |
| RU2184147C2 (ru) | 2002-06-27 |
| US20030129185A1 (en) | 2003-07-10 |
| CZ117399A3 (cs) | 1999-09-15 |
| ATE512224T1 (de) | 2011-06-15 |
| TR199900722T2 (xx) | 1999-12-21 |
| NO991591L (no) | 1999-06-01 |
| EP0960936A1 (en) | 1999-12-01 |
| IL129286A0 (en) | 2000-02-17 |
| EP0960936A4 (en) | 2005-01-19 |
| NO325178B1 (no) | 2008-02-11 |
| CA2267072A1 (en) | 1998-04-09 |
| TW530064B (en) | 2003-05-01 |
| CN1271205C (zh) | 2006-08-23 |
| CZ296790B6 (cs) | 2006-06-14 |
| US6699974B2 (en) | 2004-03-02 |
| NO991591D0 (no) | 1999-03-31 |
| PL332742A1 (en) | 1999-10-11 |
| CA2267072C (en) | 2004-11-30 |
| HK1024261A1 (en) | 2000-10-05 |
| CN1765928A (zh) | 2006-05-03 |
| US7892543B2 (en) | 2011-02-22 |
| KR100388256B1 (ko) | 2003-06-19 |
| AU4399297A (en) | 1998-04-24 |
| ZA978865B (en) | 1998-04-20 |
| KR20000048884A (ko) | 2000-07-25 |
| PL187642B1 (pl) | 2004-08-31 |
| SK44399A3 (en) | 2000-05-16 |
| CN1235639A (zh) | 1999-11-17 |
| US20030045691A1 (en) | 2003-03-06 |
| WO1998014580A1 (fr) | 1998-04-09 |
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