UA76934C2 - Reconstructed human anti-hm 1.24 antibody, coding dna, vector, host cell, method for production of reconstructed human antibody, pharmaceutical composition and drug for treating myeloma containing reconstructed human anti-hm 1.24 antibody - Google Patents
Reconstructed human anti-hm 1.24 antibody, coding dna, vector, host cell, method for production of reconstructed human antibody, pharmaceutical composition and drug for treating myeloma containing reconstructed human anti-hm 1.24 antibody Download PDFInfo
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-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/734—Complement-dependent cytotoxicity [CDC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP26475696 | 1996-10-04 | ||
| PCT/JP1997/003553 WO1998014580A1 (fr) | 1996-10-04 | 1997-10-03 | Anticorps anti-hm1.24 humain reconstitue |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA76934C2 true UA76934C2 (en) | 2006-10-16 |
Family
ID=17407753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA99042469A UA76934C2 (en) | 1996-10-04 | 1997-03-10 | Reconstructed human anti-hm 1.24 antibody, coding dna, vector, host cell, method for production of reconstructed human antibody, pharmaceutical composition and drug for treating myeloma containing reconstructed human anti-hm 1.24 antibody |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US6699974B2 (cs) |
| EP (1) | EP0960936B1 (cs) |
| KR (1) | KR100388256B1 (cs) |
| CN (2) | CN1765928A (cs) |
| AT (1) | ATE512224T1 (cs) |
| AU (1) | AU715156B2 (cs) |
| BR (1) | BR9712488A (cs) |
| CA (1) | CA2267072C (cs) |
| CZ (1) | CZ296790B6 (cs) |
| IL (1) | IL129286A0 (cs) |
| NO (1) | NO325178B1 (cs) |
| PL (1) | PL187642B1 (cs) |
| RU (1) | RU2184147C2 (cs) |
| SK (1) | SK44399A3 (cs) |
| TR (1) | TR199900722T2 (cs) |
| TW (1) | TW530064B (cs) |
| UA (1) | UA76934C2 (cs) |
| WO (1) | WO1998014580A1 (cs) |
| ZA (1) | ZA978865B (cs) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE297219T1 (de) | 1997-02-12 | 2005-06-15 | Chugai Pharmaceutical Co Ltd | Antikörper als arzneimittel gegen lymphocytische tumore (ausschliesslich myelome) |
| EP0972524A4 (en) * | 1997-02-28 | 2001-03-28 | Chugai Pharmaceutical Co Ltd | LYMPHOCYTE ACTIVATION INHIBITORS |
| KR100362974B1 (ko) * | 1997-10-14 | 2002-11-30 | 츄가이 세이야꾸 가부시키가이샤 | 림프구계 종양에 대한 항체의 증진제 |
| WO1999043703A1 (fr) * | 1998-02-25 | 1999-09-02 | Chugai Seiyaku Kabushiki Kaisha | Technique de dosage immunochimique de l'anticorps anti-hm1.24 |
| CA2343054C (en) | 1998-09-18 | 2007-10-30 | Chugai Seiyaku Kabushiki Kaisha | Method for detection or measurement of plasmacytoma cells |
| EP1176194B1 (en) * | 1999-05-10 | 2005-07-20 | Chugai Seiyaku Kabushiki Kaisha | Method of cell cultivation |
| KR20020025990A (ko) | 1999-08-23 | 2002-04-04 | 나가야마 오사무 | 에이치엠1.24 항원의 발현 증강제 |
| WO2001077362A1 (fr) * | 2000-04-06 | 2001-10-18 | Chugai Seiyaku Kabushiki Kaisha | Dosage immunologique d'anticorps anti hm1 . 24 |
| JP5485489B2 (ja) | 2000-08-11 | 2014-05-07 | 中外製薬株式会社 | 抗体含有安定化製剤 |
| US7592005B2 (en) * | 2000-12-28 | 2009-09-22 | Kirin Beer Kabushiki Kaisha | Monoclonal antibody |
| US7931897B2 (en) | 2001-02-07 | 2011-04-26 | Chugai Seiyaku Kabushiki Kaisha | Therapeutic agent for hematopoietic tumors |
| WO2002072615A1 (fr) | 2001-03-09 | 2002-09-19 | Chugai Seiyaku Kabushiki Kaisha | Methode de purification de proteines |
| CA2441228A1 (en) * | 2001-03-23 | 2002-10-03 | Aphton Corporation | Combination treatment of pancreatic cancer |
| JP4297689B2 (ja) * | 2001-04-13 | 2009-07-15 | 中外製薬株式会社 | 抗原の発現量を定量する方法 |
| US20090191232A1 (en) * | 2001-05-04 | 2009-07-30 | Gevas Philip C | Combination therapy for the treatment of tumors |
| CN101240022B (zh) * | 2001-06-22 | 2012-07-18 | 中外制药株式会社 | 含有抗磷脂酰肌醇蛋白聚糖3抗体的细胞生长抑制剂 |
| CA2450898A1 (en) * | 2001-07-09 | 2003-01-23 | Aphton Corporation | Treatment and prevention of cancerous and pre-cancerous conditions of the liver, lung and esophagus |
| EP1475100B1 (en) * | 2002-02-14 | 2015-05-06 | Chugai Seiyaku Kabushiki Kaisha | Use of acetic acid for suppressing Fe ion induced problems in formulations of anti-HM1.24 or anti-IL6R antibodies |
| US20080219974A1 (en) * | 2002-03-01 | 2008-09-11 | Bernett Matthew J | Optimized antibodies that target hm1.24 |
| EP1513879B1 (en) * | 2002-06-03 | 2018-08-22 | Genentech, Inc. | Synthetic antibody phage libraries |
| EP1541165A4 (en) | 2002-08-27 | 2009-06-24 | Chugai Pharmaceutical Co Ltd | METHOD FOR STABILIZING PROTEIN PREPARATION |
| US8420789B2 (en) | 2002-09-11 | 2013-04-16 | Chugai Seiyaku Kabushiki Kaisha | Method for removing DNA contaminants from a protein-containing sample |
| US7235376B2 (en) * | 2003-03-28 | 2007-06-26 | Receptor Biologix, Inc. | Gastrin hormone immunoassays |
| WO2005012531A2 (en) * | 2003-08-01 | 2005-02-10 | Genentech, Inc. | Antibody cdr polypeptide sequences with restricted diversity |
| JPWO2005014651A1 (ja) * | 2003-08-11 | 2006-11-24 | 中外製薬株式会社 | 糖鎖改変抗ｈｍ１．２４抗体 |
| JP4794303B2 (ja) * | 2003-10-10 | 2011-10-19 | 中外製薬株式会社 | 固形腫瘍治療剤 |
| CN102373214B (zh) * | 2003-11-05 | 2014-07-09 | 罗氏格黎卡特股份公司 | 具有增加的Fc受体结合亲和性和效应子功能的CD20抗体 |
| US20060122377A1 (en) * | 2004-02-19 | 2006-06-08 | Genentech, Inc. | CDR-repaired antibodies |
| WO2005095459A2 (en) * | 2004-03-29 | 2005-10-13 | Receptor Biologix, Inc. | Monoclonal antibodies to gastrin hormone |
| CA2580965C (en) * | 2004-09-22 | 2014-04-08 | Receptor Biologix, Inc. | Monoclonal antibodies to progastrin |
| AU2012216702B2 (en) * | 2005-08-26 | 2014-12-04 | Roche Glycart Ag | Modified antigen binding molecules with altered cell signaling activity |
| EP1931712B1 (en) * | 2005-08-26 | 2018-12-05 | Roche Glycart AG | Modified antigen binding molecules with altered cell signaling activity |
| EP2465870A1 (en) | 2005-11-07 | 2012-06-20 | Genentech, Inc. | Binding polypeptides with diversified and consensus VH/VL hypervariable sequences |
| US20070237764A1 (en) * | 2005-12-02 | 2007-10-11 | Genentech, Inc. | Binding polypeptides with restricted diversity sequences |
| WO2007074880A1 (ja) | 2005-12-28 | 2007-07-05 | Chugai Seiyaku Kabushiki Kaisha | 抗体含有安定化製剤 |
| WO2008036688A2 (en) * | 2006-09-18 | 2008-03-27 | Xencor, Inc. | Optimized antibodies that target hm1.24 |
| PE20091174A1 (es) | 2007-12-27 | 2009-08-03 | Chugai Pharmaceutical Co Ltd | Formulacion liquida con contenido de alta concentracion de anticuerpo |
| US8709424B2 (en) * | 2009-09-03 | 2014-04-29 | Merck Sharp & Dohme Corp. | Anti-GITR antibodies |
| AR080428A1 (es) | 2010-01-20 | 2012-04-11 | Chugai Pharmaceutical Co Ltd | Formulaciones liquidas estabilizadas contentivas de anticuerpos |
| EP2735315B1 (en) | 2011-07-19 | 2019-10-02 | Chugai Seiyaku Kabushiki Kaisha | Stable protein-containing preparation containing argininamide or valinamide |
| MY182178A (en) | 2011-09-01 | 2021-01-18 | Chugai Pharmaceutical Co Ltd | Method for preparing a composition comprising highly concentrated antibodies by ultrafiltration |
| AU2014370873B2 (en) | 2013-12-27 | 2020-06-11 | Chugai Seiyaku Kabushiki Kaisha | Method for purifying antibody having low isoelectric point |
| US20170362304A1 (en) | 2014-08-20 | 2017-12-21 | Chugai Seiyaku Kabushiki Kaisha | Method for measuring viscosity of protein solution |
| MA40764A (fr) | 2014-09-26 | 2017-08-01 | Chugai Pharmaceutical Co Ltd | Agent thérapeutique induisant une cytotoxicité |
| US11583576B2 (en) | 2017-06-15 | 2023-02-21 | Cancer Advances Inc. | Compositions and methods for inducing humoral and cellular immunities against tumors and cancer |
| US12150978B2 (en) | 2017-06-15 | 2024-11-26 | Cancer Advances Inc. | Compositions and methods for preventing tumors and cancer |
| CN109748964B (zh) * | 2017-11-01 | 2020-11-17 | 深圳宾德生物技术有限公司 | CD317单链抗体317scFv、其编码序列及制备方法和应用 |
| CN113226367B (zh) | 2018-04-06 | 2025-05-06 | Atyr医药公司 | 包括抗nrp2抗体的组合物和方法 |
| WO2019225568A1 (ja) | 2018-05-21 | 2019-11-28 | 中外製薬株式会社 | ガラス容器に封入された凍結乾燥製剤 |
| EP3805112A4 (en) | 2018-05-28 | 2022-03-09 | Chugai Seiyaku Kabushiki Kaisha | Filling nozzle |
| EP4037711A4 (en) | 2019-10-03 | 2024-02-14 | Atyr Pharma, Inc. | COMPOSITIONS AND METHODS USING ANTI-NRP2 ANTIBODIES |
| WO2023058723A1 (ja) | 2021-10-08 | 2023-04-13 | 中外製薬株式会社 | プレフィルドシリンジ製剤の調製方法 |
| AU2023262861A1 (en) | 2022-04-26 | 2024-11-07 | Chugai Seiyaku Kabushiki Kaisha | Pharmaceutical-preparation-containing syringe equipped with filter |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO873164L (no) * | 1986-07-30 | 1988-02-01 | Teijin Ltd | Muse-humane kimaere antistoffer. |
| US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| GB8928874D0 (en) * | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
| GB9014932D0 (en) * | 1990-07-05 | 1990-08-22 | Celltech Ltd | Recombinant dna product and method |
| TW205553B (cs) * | 1991-04-25 | 1993-05-11 | Chugai Pharmaceutical Co Ltd | |
| CA2195557C (en) * | 1994-08-12 | 2006-10-17 | Shui-On Leung | Immunoconjugates and humanized antibodies specific for b-cell lymphoma and leukemia cells |
| ATE297219T1 (de) * | 1997-02-12 | 2005-06-15 | Chugai Pharmaceutical Co Ltd | Antikörper als arzneimittel gegen lymphocytische tumore (ausschliesslich myelome) |
| US20020034507A1 (en) * | 1997-02-28 | 2002-03-21 | Yasuo Koishihara | Inhibitor of lymphocyte activation |
| US7052873B2 (en) * | 1997-10-03 | 2006-05-30 | Chugai Seiyaku Kabushiki Kaisha | Natural human antibody |
| KR100362974B1 (ko) * | 1997-10-14 | 2002-11-30 | 츄가이 세이야꾸 가부시키가이샤 | 림프구계 종양에 대한 항체의 증진제 |
| JP2006512895A (ja) * | 2002-06-28 | 2006-04-20 | ドマンティス リミテッド | リガンド |
-
1997
- 1997-03-10 UA UA99042469A patent/UA76934C2/uk unknown
- 1997-10-03 TR TR1999/00722T patent/TR199900722T2/xx unknown
- 1997-10-03 BR BR9712488-5A patent/BR9712488A/pt not_active Application Discontinuation
- 1997-10-03 CN CNA2005100687876A patent/CN1765928A/zh active Pending
- 1997-10-03 KR KR10-1999-7002902A patent/KR100388256B1/ko not_active Expired - Fee Related
- 1997-10-03 SK SK443-99A patent/SK44399A3/sk unknown
- 1997-10-03 CN CNB971992150A patent/CN1271205C/zh not_active Expired - Fee Related
- 1997-10-03 PL PL97332742A patent/PL187642B1/pl not_active IP Right Cessation
- 1997-10-03 RU RU99109034/13A patent/RU2184147C2/ru not_active IP Right Cessation
- 1997-10-03 ZA ZA9708865A patent/ZA978865B/xx unknown
- 1997-10-03 AU AU43992/97A patent/AU715156B2/en not_active Ceased
- 1997-10-03 US US09/269,921 patent/US6699974B2/en not_active Expired - Lifetime
- 1997-10-03 TW TW086114474A patent/TW530064B/zh not_active IP Right Cessation
- 1997-10-03 CZ CZ0117399A patent/CZ296790B6/cs not_active IP Right Cessation
- 1997-10-03 WO PCT/JP1997/003553 patent/WO1998014580A1/ja active IP Right Grant
- 1997-10-03 IL IL12928697A patent/IL129286A0/xx not_active IP Right Cessation
- 1997-10-03 EP EP97942246A patent/EP0960936B1/en not_active Expired - Lifetime
- 1997-10-03 CA CA002267072A patent/CA2267072C/en not_active Expired - Fee Related
- 1997-10-03 AT AT97942246T patent/ATE512224T1/de not_active IP Right Cessation
-
1999
- 1999-03-31 NO NO19991591A patent/NO325178B1/no unknown
-
2002
- 2002-08-13 US US10/218,253 patent/US7892543B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| KR20000048884A (ko) | 2000-07-25 |
| TW530064B (en) | 2003-05-01 |
| EP0960936B1 (en) | 2011-06-08 |
| SK44399A3 (en) | 2000-05-16 |
| TR199900722T2 (xx) | 1999-12-21 |
| NO325178B1 (no) | 2008-02-11 |
| ZA978865B (en) | 1998-04-20 |
| CN1235639A (zh) | 1999-11-17 |
| BR9712488A (pt) | 1999-10-19 |
| US20030129185A1 (en) | 2003-07-10 |
| PL187642B1 (pl) | 2004-08-31 |
| AU4399297A (en) | 1998-04-24 |
| ATE512224T1 (de) | 2011-06-15 |
| RU2184147C2 (ru) | 2002-06-27 |
| CA2267072C (en) | 2004-11-30 |
| NO991591D0 (no) | 1999-03-31 |
| US6699974B2 (en) | 2004-03-02 |
| CA2267072A1 (en) | 1998-04-09 |
| EP0960936A1 (en) | 1999-12-01 |
| HK1024261A1 (en) | 2000-10-05 |
| KR100388256B1 (ko) | 2003-06-19 |
| CN1765928A (zh) | 2006-05-03 |
| AU715156B2 (en) | 2000-01-20 |
| PL332742A1 (en) | 1999-10-11 |
| CN1271205C (zh) | 2006-08-23 |
| NO991591L (no) | 1999-06-01 |
| CZ117399A3 (cs) | 1999-09-15 |
| US20030045691A1 (en) | 2003-03-06 |
| CZ296790B6 (cs) | 2006-06-14 |
| US7892543B2 (en) | 2011-02-22 |
| IL129286A0 (en) | 2000-02-17 |
| EP0960936A4 (en) | 2005-01-19 |
| WO1998014580A1 (fr) | 1998-04-09 |
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