UA73071C2 - Improved method for processing activated protein c - Google Patents
Improved method for processing activated protein c Download PDFInfo
- Publication number
- UA73071C2 UA73071C2 UA99105788A UA99105788A UA73071C2 UA 73071 C2 UA73071 C2 UA 73071C2 UA 99105788 A UA99105788 A UA 99105788A UA 99105788 A UA99105788 A UA 99105788A UA 73071 C2 UA73071 C2 UA 73071C2
- Authority
- UA
- Ukraine
- Prior art keywords
- activated protein
- protein
- des
- buffer
- mentioned
- Prior art date
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Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4866—Protein C (3.4.21.69)
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- A—HUMAN NECESSITIES
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6464—Protein C (3.4.21.69)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Vascular Medicine (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US4525597P | 1997-04-28 | 1997-04-28 | |
PCT/US1998/008384 WO1998048822A1 (en) | 1997-04-28 | 1998-04-24 | Improved methods for processing activated protein c |
Publications (1)
Publication Number | Publication Date |
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UA73071C2 true UA73071C2 (en) | 2005-06-15 |
Family
ID=21936854
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
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UA99105788A UA73071C2 (en) | 1997-04-28 | 1998-04-24 | Improved method for processing activated protein c |
UA99105884A UA55448C2 (uk) | 1997-04-28 | 1998-04-24 | Стійка ліофілізована лікарська форма з активованим білком с (варіанти) та виріб, який її містить |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
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UA99105884A UA55448C2 (uk) | 1997-04-28 | 1998-04-24 | Стійка ліофілізована лікарська форма з активованим білком с (варіанти) та виріб, який її містить |
Country Status (35)
Country | Link |
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US (4) | US6159468A (de) |
EP (2) | EP0875252B1 (de) |
JP (2) | JP4383546B2 (de) |
KR (2) | KR100564189B1 (de) |
CN (2) | CN1235638C (de) |
AR (2) | AR015598A1 (de) |
AT (1) | ATE285788T1 (de) |
AU (2) | AU743531B2 (de) |
BR (2) | BR9809304B1 (de) |
CA (2) | CA2288143C (de) |
CO (2) | CO4940438A1 (de) |
CZ (1) | CZ298429B6 (de) |
DE (1) | DE69828330T2 (de) |
DK (1) | DK0875252T3 (de) |
EA (2) | EA004881B1 (de) |
EG (1) | EG23685A (de) |
ES (1) | ES2234072T3 (de) |
HK (1) | HK1016472A1 (de) |
HU (2) | HU224826B1 (de) |
ID (2) | ID22933A (de) |
IL (2) | IL132502A0 (de) |
IN (2) | IN187157B (de) |
MY (2) | MY118591A (de) |
NO (2) | NO995134L (de) |
NZ (2) | NZ337828A (de) |
PE (2) | PE84799A1 (de) |
PL (2) | PL195090B1 (de) |
PT (1) | PT875252E (de) |
SI (1) | SI0875252T1 (de) |
SV (2) | SV1998000050A (de) |
TR (2) | TR199902631T2 (de) |
TW (2) | TW585871B (de) |
UA (2) | UA73071C2 (de) |
WO (2) | WO1998048822A1 (de) |
ZA (2) | ZA983497B (de) |
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1998
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- 1998-04-24 US US09/065,975 patent/US6159468A/en not_active Expired - Lifetime
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- 1998-04-24 BR BR9809292-8A patent/BR9809292A/pt not_active Application Discontinuation
- 1998-04-24 CO CO98022609A patent/CO4950523A1/es unknown
- 1998-04-24 IL IL13232598A patent/IL132325A/xx not_active IP Right Cessation
- 1998-04-24 ZA ZA9803496A patent/ZA983496B/xx unknown
- 1998-04-24 NZ NZ500346A patent/NZ500346A/en unknown
- 1998-04-24 US US09/065,872 patent/US6162629A/en not_active Expired - Lifetime
- 1998-04-26 EG EG45198A patent/EG23685A/xx active
- 1998-04-27 IN IN752CA1998 patent/IN187157B/en unknown
- 1998-04-27 IN IN751CA1998 patent/IN183798B/en unknown
- 1998-04-27 MY MYPI98001900A patent/MY118591A/en unknown
- 1998-04-27 MY MYPI98001899A patent/MY120984A/en unknown
- 1998-04-27 SV SV1998000050A patent/SV1998000050A/es not_active Application Discontinuation
- 1998-04-27 SV SV1998000051A patent/SV1998000051A/es not_active Application Discontinuation
- 1998-04-28 TW TW087106549A patent/TW585871B/zh not_active IP Right Cessation
- 1998-04-28 EP EP98303311A patent/EP0875252B1/de not_active Expired - Lifetime
- 1998-04-28 DE DE69828330T patent/DE69828330T2/de not_active Expired - Lifetime
- 1998-04-28 TW TW087106558A patent/TWI242443B/zh not_active IP Right Cessation
- 1998-04-28 SI SI9830752T patent/SI0875252T1/xx unknown
- 1998-04-28 DK DK98303311T patent/DK0875252T3/da active
- 1998-04-28 AT AT98303311T patent/ATE285788T1/de not_active IP Right Cessation
- 1998-04-28 ES ES98303311T patent/ES2234072T3/es not_active Expired - Lifetime
- 1998-04-28 PT PT98303311T patent/PT875252E/pt unknown
- 1998-04-28 EP EP98303312A patent/EP0875563A3/de not_active Withdrawn
-
1999
- 1999-04-08 HK HK99101418A patent/HK1016472A1/xx not_active IP Right Cessation
- 1999-10-21 NO NO995134A patent/NO995134L/no not_active Application Discontinuation
- 1999-10-25 NO NO995198A patent/NO995198D0/no not_active Application Discontinuation
-
2000
- 2000-09-14 US US09/662,232 patent/US6395270B1/en not_active Expired - Lifetime
- 2000-09-21 US US09/667,570 patent/US6436397B1/en not_active Expired - Lifetime
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