UA71653C2 - A METHOD FOR THE PREPARATION OF a-(2,4-DISULFOPHENYL)-N-TRET-BUTYLNITRONE AND SALTS THEREOF - Google Patents

A METHOD FOR THE PREPARATION OF a-(2,4-DISULFOPHENYL)-N-TRET-BUTYLNITRONE AND SALTS THEREOF Download PDF

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Publication number
UA71653C2
UA71653C2 UA2002065094A UA2002065094A UA71653C2 UA 71653 C2 UA71653 C2 UA 71653C2 UA 2002065094 A UA2002065094 A UA 2002065094A UA 2002065094 A UA2002065094 A UA 2002065094A UA 71653 C2 UA71653 C2 UA 71653C2
Authority
UA
Ukraine
Prior art keywords
tert
reaction
butylnitrone
acetate
disulfophenyl
Prior art date
Application number
UA2002065094A
Other languages
English (en)
Ukrainian (uk)
Original Assignee
Astrazeneca Ab
Centaur Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab, Centaur Pharmaceuticals Inc filed Critical Astrazeneca Ab
Publication of UA71653C2 publication Critical patent/UA71653C2/uk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01Sulfonic acids
    • C07C309/28Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/45Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/46Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton having the sulfo groups bound to carbon atoms of non-condensed six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/02Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof
    • C07C303/22Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof from sulfonic acids, by reactions not involving the formation of sulfo or halosulfonyl groups; from sulfonic halides by reactions not involving the formation of halosulfonyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/32Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of salts of sulfonic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
UA2002065094A 2000-01-10 2001-04-01 A METHOD FOR THE PREPARATION OF a-(2,4-DISULFOPHENYL)-N-TRET-BUTYLNITRONE AND SALTS THEREOF UA71653C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0000055A SE0000055D0 (sv) 2000-01-10 2000-01-10 Novel process
PCT/SE2001/000007 WO2001051460A1 (en) 2000-01-10 2001-01-04 NOVEL PROCESS FOR THE PREPARATION OF α-(2-4-DISULFOPHENYL)-N-TERT-BUTYLNITRONE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF

Publications (1)

Publication Number Publication Date
UA71653C2 true UA71653C2 (en) 2004-12-15

Family

ID=20278055

Family Applications (1)

Application Number Title Priority Date Filing Date
UA2002065094A UA71653C2 (en) 2000-01-10 2001-04-01 A METHOD FOR THE PREPARATION OF a-(2,4-DISULFOPHENYL)-N-TRET-BUTYLNITRONE AND SALTS THEREOF

Country Status (32)

Country Link
US (1) US6479697B2 (he)
EP (1) EP1265856B1 (he)
JP (1) JP3748821B2 (he)
KR (1) KR100687167B1 (he)
CN (1) CN1198798C (he)
AR (1) AR029431A1 (he)
AT (1) ATE263753T1 (he)
AU (1) AU783255B2 (he)
BR (1) BR0107483A (he)
CA (1) CA2395971A1 (he)
CO (1) CO5280203A1 (he)
DE (1) DE60102679T2 (he)
DK (1) DK1265856T3 (he)
EE (1) EE200200385A (he)
ES (1) ES2217114T3 (he)
HU (1) HU225298B1 (he)
IL (2) IL150403A0 (he)
IS (1) IS6456A (he)
MX (1) MXPA02006674A (he)
MY (1) MY122830A (he)
NO (1) NO20023316L (he)
NZ (1) NZ519828A (he)
PL (1) PL357106A1 (he)
PT (1) PT1265856E (he)
RU (1) RU2259996C2 (he)
SE (1) SE0000055D0 (he)
SK (1) SK9932002A3 (he)
TR (1) TR200401307T4 (he)
TW (1) TW572880B (he)
UA (1) UA71653C2 (he)
WO (1) WO2001051460A1 (he)
ZA (1) ZA200204872B (he)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100491791C (zh) 2002-02-14 2009-05-27 威利特国际有限公司 电磁阀
US20050059638A1 (en) * 2003-08-04 2005-03-17 Kelly Michael G. Aryl, heteroaromatic and bicyclic aryl nitrone compounds, prodrugs and pharmaceutical compositions of the same to treat human disorders
US20050182060A1 (en) * 2004-02-13 2005-08-18 Kelly Michael G. 2-Substituted and 4-substituted aryl nitrone compounds
US20080193783A1 (en) * 2004-12-01 2008-08-14 Toyo Boseki Kabushiki Kaisha Polyester Resin Film and Process for Producing the Same
SG158148A1 (en) 2004-12-22 2010-01-29 Ambrx Inc Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides
WO2007013844A1 (en) * 2005-07-26 2007-02-01 Astrazeneca Ab Use of 4-[(tert-butylimino)benzene-1,3-disulfonate n-oxide against nausea
WO2009102808A2 (en) 2008-02-12 2009-08-20 Tosk, Incorporated Doxorubicin adjuvants to reduce toxicity and methods for using the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1437188A (fr) * 1964-06-17 1966-04-29 Du Pont Procédé de fabrication d'alpha-phényl-nu-méthyl nitrone
US5488145A (en) * 1993-12-23 1996-01-30 Oklahoma Medical Research Foundation 2,4-disulfonyl phenyl butyl nitrone, its salts, and their use as pharmaceutical free radical traps
SE9802507D0 (sv) * 1998-07-10 1998-07-10 Astra Ab Novel salts

Also Published As

Publication number Publication date
BR0107483A (pt) 2002-09-03
ATE263753T1 (de) 2004-04-15
JP3748821B2 (ja) 2006-02-22
JP2003519678A (ja) 2003-06-24
AU783255B2 (en) 2005-10-06
EP1265856B1 (en) 2004-04-07
AU2720301A (en) 2001-07-24
AR029431A1 (es) 2003-06-25
DK1265856T3 (da) 2004-07-05
PL357106A1 (en) 2004-07-12
MY122830A (en) 2006-05-31
DE60102679D1 (de) 2004-05-13
HU225298B1 (en) 2006-09-28
DE60102679T2 (de) 2004-12-09
HUP0204111A2 (hu) 2003-03-28
TR200401307T4 (tr) 2004-07-21
TW572880B (en) 2004-01-21
RU2259996C2 (ru) 2005-09-10
HUP0204111A3 (en) 2005-05-30
KR100687167B1 (ko) 2007-02-27
US6479697B2 (en) 2002-11-12
CA2395971A1 (en) 2001-07-19
ES2217114T3 (es) 2004-11-01
NO20023316D0 (no) 2002-07-09
CN1395559A (zh) 2003-02-05
EP1265856A1 (en) 2002-12-18
SK9932002A3 (en) 2003-03-04
SE0000055D0 (sv) 2000-01-10
KR20020091077A (ko) 2002-12-05
IL150403A (he) 2007-06-03
NO20023316L (no) 2002-07-09
PT1265856E (pt) 2004-07-30
NZ519828A (en) 2004-11-26
EE200200385A (et) 2003-12-15
CN1198798C (zh) 2005-04-27
US20020128318A1 (en) 2002-09-12
WO2001051460A1 (en) 2001-07-19
IS6456A (is) 2002-07-04
IL150403A0 (en) 2002-12-01
MXPA02006674A (es) 2004-09-10
RU2002118320A (ru) 2004-02-27
ZA200204872B (en) 2003-10-07
CO5280203A1 (es) 2003-05-30

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