DK1265856T3 - Hidtil ukendt fremgangsmåde til fremstillingen af alpha-(2,4-disulfophenyl)-N-tert-butylnitron og farmaceutisk acceptable salte deraf - Google Patents

Hidtil ukendt fremgangsmåde til fremstillingen af alpha-(2,4-disulfophenyl)-N-tert-butylnitron og farmaceutisk acceptable salte deraf

Info

Publication number
DK1265856T3
DK1265856T3 DK01901619T DK01901619T DK1265856T3 DK 1265856 T3 DK1265856 T3 DK 1265856T3 DK 01901619 T DK01901619 T DK 01901619T DK 01901619 T DK01901619 T DK 01901619T DK 1265856 T3 DK1265856 T3 DK 1265856T3
Authority
DK
Denmark
Prior art keywords
butylnitrone
disulfophenyl
tert
alpha
preparation
Prior art date
Application number
DK01901619T
Other languages
Danish (da)
English (en)
Inventor
Henry Kruk
John Mcginley
Joergen Blixt
Sergei Pouhov
John Vajda
Original Assignee
Renovis
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Renovis, Astrazeneca Ab filed Critical Renovis
Application granted granted Critical
Publication of DK1265856T3 publication Critical patent/DK1265856T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/45—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/46—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton having the sulfo groups bound to carbon atoms of non-condensed six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/02—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof
    • C07C303/22—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof from sulfonic acids, by reactions not involving the formation of sulfo or halosulfonyl groups; from sulfonic halides by reactions not involving the formation of halosulfonyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/32—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of salts of sulfonic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK01901619T 2000-01-10 2001-01-04 Hidtil ukendt fremgangsmåde til fremstillingen af alpha-(2,4-disulfophenyl)-N-tert-butylnitron og farmaceutisk acceptable salte deraf DK1265856T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0000055A SE0000055D0 (sv) 2000-01-10 2000-01-10 Novel process

Publications (1)

Publication Number Publication Date
DK1265856T3 true DK1265856T3 (da) 2004-07-05

Family

ID=20278055

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01901619T DK1265856T3 (da) 2000-01-10 2001-01-04 Hidtil ukendt fremgangsmåde til fremstillingen af alpha-(2,4-disulfophenyl)-N-tert-butylnitron og farmaceutisk acceptable salte deraf

Country Status (32)

Country Link
US (1) US6479697B2 (he)
EP (1) EP1265856B1 (he)
JP (1) JP3748821B2 (he)
KR (1) KR100687167B1 (he)
CN (1) CN1198798C (he)
AR (1) AR029431A1 (he)
AT (1) ATE263753T1 (he)
AU (1) AU783255B2 (he)
BR (1) BR0107483A (he)
CA (1) CA2395971A1 (he)
CO (1) CO5280203A1 (he)
DE (1) DE60102679T2 (he)
DK (1) DK1265856T3 (he)
EE (1) EE200200385A (he)
ES (1) ES2217114T3 (he)
HU (1) HU225298B1 (he)
IL (2) IL150403A0 (he)
IS (1) IS6456A (he)
MX (1) MXPA02006674A (he)
MY (1) MY122830A (he)
NO (1) NO20023316L (he)
NZ (1) NZ519828A (he)
PL (1) PL357106A1 (he)
PT (1) PT1265856E (he)
RU (1) RU2259996C2 (he)
SE (1) SE0000055D0 (he)
SK (1) SK9932002A3 (he)
TR (1) TR200401307T4 (he)
TW (1) TW572880B (he)
UA (1) UA71653C2 (he)
WO (1) WO2001051460A1 (he)
ZA (1) ZA200204872B (he)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100491791C (zh) 2002-02-14 2009-05-27 威利特国际有限公司 电磁阀
US20050059638A1 (en) * 2003-08-04 2005-03-17 Kelly Michael G. Aryl, heteroaromatic and bicyclic aryl nitrone compounds, prodrugs and pharmaceutical compositions of the same to treat human disorders
US20050182060A1 (en) * 2004-02-13 2005-08-18 Kelly Michael G. 2-Substituted and 4-substituted aryl nitrone compounds
US20080193783A1 (en) * 2004-12-01 2008-08-14 Toyo Boseki Kabushiki Kaisha Polyester Resin Film and Process for Producing the Same
SG158148A1 (en) 2004-12-22 2010-01-29 Ambrx Inc Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides
WO2007013844A1 (en) * 2005-07-26 2007-02-01 Astrazeneca Ab Use of 4-[(tert-butylimino)benzene-1,3-disulfonate n-oxide against nausea
WO2009102808A2 (en) 2008-02-12 2009-08-20 Tosk, Incorporated Doxorubicin adjuvants to reduce toxicity and methods for using the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1437188A (fr) * 1964-06-17 1966-04-29 Du Pont Procédé de fabrication d'alpha-phényl-nu-méthyl nitrone
US5488145A (en) * 1993-12-23 1996-01-30 Oklahoma Medical Research Foundation 2,4-disulfonyl phenyl butyl nitrone, its salts, and their use as pharmaceutical free radical traps
SE9802507D0 (sv) * 1998-07-10 1998-07-10 Astra Ab Novel salts

Also Published As

Publication number Publication date
BR0107483A (pt) 2002-09-03
ATE263753T1 (de) 2004-04-15
JP3748821B2 (ja) 2006-02-22
JP2003519678A (ja) 2003-06-24
AU783255B2 (en) 2005-10-06
EP1265856B1 (en) 2004-04-07
AU2720301A (en) 2001-07-24
AR029431A1 (es) 2003-06-25
PL357106A1 (en) 2004-07-12
MY122830A (en) 2006-05-31
DE60102679D1 (de) 2004-05-13
HU225298B1 (en) 2006-09-28
DE60102679T2 (de) 2004-12-09
HUP0204111A2 (hu) 2003-03-28
TR200401307T4 (tr) 2004-07-21
TW572880B (en) 2004-01-21
RU2259996C2 (ru) 2005-09-10
HUP0204111A3 (en) 2005-05-30
KR100687167B1 (ko) 2007-02-27
US6479697B2 (en) 2002-11-12
CA2395971A1 (en) 2001-07-19
UA71653C2 (en) 2004-12-15
ES2217114T3 (es) 2004-11-01
NO20023316D0 (no) 2002-07-09
CN1395559A (zh) 2003-02-05
EP1265856A1 (en) 2002-12-18
SK9932002A3 (en) 2003-03-04
SE0000055D0 (sv) 2000-01-10
KR20020091077A (ko) 2002-12-05
IL150403A (he) 2007-06-03
NO20023316L (no) 2002-07-09
PT1265856E (pt) 2004-07-30
NZ519828A (en) 2004-11-26
EE200200385A (et) 2003-12-15
CN1198798C (zh) 2005-04-27
US20020128318A1 (en) 2002-09-12
WO2001051460A1 (en) 2001-07-19
IS6456A (is) 2002-07-04
IL150403A0 (en) 2002-12-01
MXPA02006674A (es) 2004-09-10
RU2002118320A (ru) 2004-02-27
ZA200204872B (en) 2003-10-07
CO5280203A1 (es) 2003-05-30

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