UA39866C2 - Похідні індолу, проміжні сполуки, фармацевтична композиція та спосіб лікування - Google Patents
Похідні індолу, проміжні сполуки, фармацевтична композиція та спосіб лікуванняInfo
- Publication number
- UA39866C2 UA39866C2 UA94095775A UA94095775A UA39866C2 UA 39866 C2 UA39866 C2 UA 39866C2 UA 94095775 A UA94095775 A UA 94095775A UA 94095775 A UA94095775 A UA 94095775A UA 39866 C2 UA39866 C2 UA 39866C2
- Authority
- UA
- Ukraine
- Prior art keywords
- mixer
- treatment
- pharmaceutical composition
- intermediate compounds
- case
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical class C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 2
- 238000005265 energy consumption Methods 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 238000009434 installation Methods 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Addiction (AREA)
- Anesthesiology (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84664092A | 1992-03-05 | 1992-03-05 | |
| PCT/US1993/001667 WO1993018032A1 (en) | 1992-03-05 | 1993-03-03 | Indole derivatives as 5-ht1 agonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA39866C2 true UA39866C2 (uk) | 2001-07-16 |
Family
ID=25298499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA94095775A UA39866C2 (uk) | 1992-03-05 | 1993-03-03 | Похідні індолу, проміжні сполуки, фармацевтична композиція та спосіб лікування |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US5594014A (OSRAM) |
| EP (1) | EP0629199B1 (OSRAM) |
| JP (1) | JPH07121943B2 (OSRAM) |
| KR (1) | KR0179073B1 (OSRAM) |
| CN (4) | CN1032309C (OSRAM) |
| AT (1) | ATE218566T1 (OSRAM) |
| AU (1) | AU666716B2 (OSRAM) |
| BR (1) | BR9306012A (OSRAM) |
| CA (1) | CA2117643C (OSRAM) |
| CZ (1) | CZ282652B6 (OSRAM) |
| DE (1) | DE69331988T2 (OSRAM) |
| DK (1) | DK0629199T3 (OSRAM) |
| EG (1) | EG20416A (OSRAM) |
| ES (1) | ES2176199T3 (OSRAM) |
| FI (1) | FI930968A7 (OSRAM) |
| HU (1) | HU219489B (OSRAM) |
| IL (1) | IL104941A (OSRAM) |
| MX (1) | MX9301197A (OSRAM) |
| MY (1) | MY109298A (OSRAM) |
| NO (1) | NO302617B1 (OSRAM) |
| NZ (1) | NZ249755A (OSRAM) |
| PL (1) | PL172388B1 (OSRAM) |
| PT (1) | PT629199E (OSRAM) |
| RU (1) | RU2124012C1 (OSRAM) |
| SK (1) | SK281938B6 (OSRAM) |
| TW (1) | TW288010B (OSRAM) |
| UA (1) | UA39866C2 (OSRAM) |
| WO (1) | WO1993018032A1 (OSRAM) |
| YU (1) | YU14893A (OSRAM) |
| ZA (1) | ZA931539B (OSRAM) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5578612A (en) * | 1990-10-15 | 1996-11-26 | Pfizer Inc. | Indole derivatives |
| US5545644A (en) * | 1990-10-15 | 1996-08-13 | Pfizer Inc. | Indole derivatives |
| US5607951A (en) * | 1990-10-15 | 1997-03-04 | Pfizer Inc | Indole derivatives |
| US5559129A (en) * | 1990-10-15 | 1996-09-24 | Pfizer Inc | Indole derivatives |
| US5559246A (en) * | 1990-10-15 | 1996-09-24 | Pfizer Inc. | Indole derivatives |
| US6380233B1 (en) | 1992-04-07 | 2002-04-30 | Pfizer Inc | Indole derivatives as 5-HT1 agonists |
| RU2101283C1 (ru) | 1992-04-07 | 1998-01-10 | Пфайзер Инк. | Производные индола или их фармацевтически приемлемые соли |
| ATE170836T1 (de) * | 1993-08-31 | 1998-09-15 | Pfizer | 5-arylindolderivate |
| GB9417310D0 (en) * | 1994-08-27 | 1994-10-19 | Pfizer Ltd | Therapeutic agents |
| GB9420503D0 (en) * | 1994-10-11 | 1994-11-23 | Pfizer Ltd | Therapeutic agents |
| GB9420529D0 (en) | 1994-10-12 | 1994-11-30 | Pfizer Ltd | Indoles |
| EA199800611A1 (ru) * | 1995-12-29 | 1999-04-29 | Берингер, Ингельхайм Фармасьютиклс, Инк. | Производные фенилтиазола с противогерпетическими свойствами |
| US6288091B1 (en) | 1995-12-29 | 2001-09-11 | Boehringer Ingelheim Ltd. | Antiherpes virus compounds and methods for their preparation and use |
| US5994352A (en) * | 1998-11-13 | 1999-11-30 | Pfizer Inc. | 5-arylindole derivatives |
| MXPA03004623A (es) | 2000-11-27 | 2003-09-05 | Pfizer Prod Inc | Agonistas selectivos del receptor ep4 en el tratamiento de la osteoporosis. |
| CA2444036A1 (en) * | 2001-04-20 | 2002-10-31 | Yanfang Li | Heterocyclylalkoxy-, -alkylthio- and -alkylaminobenzazole derivatives as 5-hydroxytryptamine-6 ligands |
| ITRM20020255A1 (it) * | 2002-05-09 | 2003-11-10 | Polifarma Spa | Tautomero enolico dell'acido 3-indolilpiruvico, suoi sali e usi terapeutici. |
| ES2199086B1 (es) * | 2002-07-31 | 2005-06-01 | Cepa Schwarz Pharma Sl | Nuevos derivados de cicloalcanodionas, procedimiento para su preparacion y sus aplicaciones farmacologicas. |
| GB0317229D0 (en) * | 2003-07-23 | 2003-08-27 | Pfizer Ltd | Improved process |
| US20140206667A1 (en) | 2012-11-14 | 2014-07-24 | Michela Gallagher | Methods and compositions for treating schizophrenia |
| AU2021215709A1 (en) * | 2020-02-04 | 2022-09-01 | Mindset Pharma Inc. | 3-pyrrolidine-indole derivatives as serotonergic psychedelic agents for the treatment of CNS disorders |
| PL243119B1 (pl) * | 2020-04-16 | 2023-06-26 | Univ Jagiellonski | Rozpuszczalne w wodzie modyfikowane pochodne aminokwasowe nadające się do leczenia chorób o podłożu neurologicznym oraz zaburzeń psychiatrycznych |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA795239B (en) * | 1978-10-12 | 1980-11-26 | Glaxo Group Ltd | Heterocyclic compounds |
| ZA815541B (en) * | 1980-08-12 | 1983-03-30 | Glaxo Group Ltd | Heterocyclic compounds |
| GB8600397D0 (en) * | 1986-01-08 | 1986-02-12 | Glaxo Group Ltd | Chemical compounds |
| GB8719167D0 (en) * | 1987-08-13 | 1987-09-23 | Glaxo Group Ltd | Chemical compounds |
| GB8724912D0 (en) * | 1987-10-23 | 1987-11-25 | Wellcome Found | Indole derivatives |
| GB8819024D0 (en) * | 1988-08-10 | 1988-09-14 | Glaxo Group Ltd | Chemical compounds |
| IL96891A0 (en) * | 1990-01-17 | 1992-03-29 | Merck Sharp & Dohme | Indole-substituted five-membered heteroaromatic compounds,their preparation and pharmaceutical compositions containing them |
| CA2042295A1 (fr) * | 1990-05-15 | 1991-11-16 | Jacques Chauveau | Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant |
| SI21560B (sl) * | 1990-06-07 | 2005-04-30 | Astrazeneca Ab | 3,5-disubstituirani indolni derivati kot "5-HT1-podobni" receptorski agonisti |
| CA2091562C (en) * | 1990-10-15 | 2001-03-27 | John Eugene Macor | Indole derivatives useful in psychotherapeutics |
| US5208248A (en) * | 1991-01-11 | 1993-05-04 | Merck Sharpe & Dohme, Ltd. | Indazole-substituted five-membered heteroaromatic compounds |
| CZ283018B6 (cs) * | 1991-02-01 | 1997-12-17 | Merck Sharp And Dohme Limited | Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi |
| TW263508B (OSRAM) * | 1991-02-12 | 1995-11-21 | Pfizer |
-
1993
- 1993-02-09 TW TW082100871A patent/TW288010B/zh active
- 1993-03-03 AU AU37330/93A patent/AU666716B2/en not_active Ceased
- 1993-03-03 EP EP93906214A patent/EP0629199B1/en not_active Expired - Lifetime
- 1993-03-03 KR KR1019940703076A patent/KR0179073B1/ko not_active Expired - Fee Related
- 1993-03-03 DK DK93906214T patent/DK0629199T3/da active
- 1993-03-03 AT AT93906214T patent/ATE218566T1/de not_active IP Right Cessation
- 1993-03-03 PT PT93906214T patent/PT629199E/pt unknown
- 1993-03-03 CZ CZ942125A patent/CZ282652B6/cs not_active IP Right Cessation
- 1993-03-03 BR BR9306012A patent/BR9306012A/pt not_active Application Discontinuation
- 1993-03-03 DE DE69331988T patent/DE69331988T2/de not_active Expired - Fee Related
- 1993-03-03 CA CA002117643A patent/CA2117643C/en not_active Expired - Fee Related
- 1993-03-03 SK SK1052-94A patent/SK281938B6/sk unknown
- 1993-03-03 UA UA94095775A patent/UA39866C2/uk unknown
- 1993-03-03 WO PCT/US1993/001667 patent/WO1993018032A1/en not_active Ceased
- 1993-03-03 MX MX9301197A patent/MX9301197A/es unknown
- 1993-03-03 US US08/284,662 patent/US5594014A/en not_active Expired - Fee Related
- 1993-03-03 JP JP5515745A patent/JPH07121943B2/ja not_active Expired - Fee Related
- 1993-03-03 PL PL93305051A patent/PL172388B1/pl not_active IP Right Cessation
- 1993-03-03 ES ES93906214T patent/ES2176199T3/es not_active Expired - Lifetime
- 1993-03-03 EG EG12893A patent/EG20416A/xx active
- 1993-03-03 RU RU94040914/04A patent/RU2124012C1/ru not_active IP Right Cessation
- 1993-03-04 IL IL104941A patent/IL104941A/en not_active IP Right Cessation
- 1993-03-04 YU YU14893A patent/YU14893A/sh unknown
- 1993-03-04 HU HU9300593A patent/HU219489B/hu not_active IP Right Cessation
- 1993-03-04 MY MYPI93000388A patent/MY109298A/en unknown
- 1993-03-04 CN CN93104036A patent/CN1032309C/zh not_active Expired - Fee Related
- 1993-03-04 FI FI930968A patent/FI930968A7/fi not_active Application Discontinuation
- 1993-03-04 ZA ZA931539A patent/ZA931539B/xx unknown
- 1993-05-03 NZ NZ249755A patent/NZ249755A/en unknown
-
1994
- 1994-09-02 NO NO943261A patent/NO302617B1/no not_active IP Right Cessation
-
1995
- 1995-11-17 CN CN95118794A patent/CN1082815C/zh not_active Expired - Fee Related
- 1995-11-17 CN CN95118795A patent/CN1044909C/zh not_active Expired - Fee Related
- 1995-11-17 CN CN95118796A patent/CN1044910C/zh not_active Expired - Fee Related
-
1996
- 1996-12-31 US US08/777,835 patent/US5717102A/en not_active Expired - Fee Related
Also Published As
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