UA27031A1 - Похідhі 3(2h)піридазиhоhу або їх фармацевтичhо прийhятhі солі, що мають протитромботичhу, позитивhу іhотропhу, судиhорозширювальhу дію й аhтиалергічhу активhість та фармацевтичhа композиція hа їх осhові - Google Patents

Похідhі 3(2h)піридазиhоhу або їх фармацевтичhо прийhятhі солі, що мають протитромботичhу, позитивhу іhотропhу, судиhорозширювальhу дію й аhтиалергічhу активhість та фармацевтичhа композиція hа їх осhові

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Publication number
UA27031A1
UA27031A1 UA5010505A UA5010505A UA27031A1 UA 27031 A1 UA27031 A1 UA 27031A1 UA 5010505 A UA5010505 A UA 5010505A UA 5010505 A UA5010505 A UA 5010505A UA 27031 A1 UA27031 A1 UA 27031A1
Authority
UA
Ukraine
Prior art keywords
pharmaceutically acceptable
pharmaceutical composition
acceptable salts
antithrombotic
basis
Prior art date
Application number
UA5010505A
Other languages
English (en)
Russian (ru)
Inventor
Танікава Кейзо
Саіто Акіра
Матсумото Такасі
Сакода Ріозо
Тсурузое Hабутомо
Сікада Кен-Іті
Original Assignee
Ніссан Кемікал Індастріз Лтд
Ниссан Кемикал Индастриз Лтд
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ніссан Кемікал Індастріз Лтд, Ниссан Кемикал Индастриз Лтд filed Critical Ніссан Кемікал Індастріз Лтд
Publication of UA27031A1 publication Critical patent/UA27031A1/uk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/22—Nitrogen and oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Фармацевтична композиція містить похідне 3(2Н)піридазинону деякої формули або його фармацевтично прийнятну сіль. Винахід стосується нових похідних 3(2Н)піридазинону та їх фармацевтично прийнятних солей, що мають інгибиторну активність стосовно агрегування тромбоцитів, кардіотонічної та вазодилаторної активності, проти-5Р8-а-активністю.
UA5010505A 1990-04-25 1991-04-19 Похідhі 3(2h)піридазиhоhу або їх фармацевтичhо прийhятhі солі, що мають протитромботичhу, позитивhу іhотропhу, судиhорозширювальhу дію й аhтиалергічhу активhість та фармацевтичhа композиція hа їх осhові UA27031A1 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10991490 1990-04-25
PCT/JP1991/000517 WO1991016314A1 (fr) 1990-04-25 1991-04-19 Derive de pyridazinone

Publications (1)

Publication Number Publication Date
UA27031A1 true UA27031A1 (uk) 2000-02-28

Family

ID=14522343

Family Applications (1)

Application Number Title Priority Date Filing Date
UA5010505A UA27031A1 (uk) 1990-04-25 1991-04-19 Похідhі 3(2h)піридазиhоhу або їх фармацевтичhо прийhятhі солі, що мають протитромботичhу, позитивhу іhотропhу, судиhорозширювальhу дію й аhтиалергічhу активhість та фармацевтичhа композиція hа їх осhові

Country Status (17)

Country Link
US (3) US5202323A (uk)
EP (1) EP0482208B1 (uk)
JP (1) JPH07107055B1 (uk)
KR (1) KR970002876B1 (uk)
AT (1) ATE194835T1 (uk)
AU (1) AU634655B2 (uk)
CA (1) CA2053863C (uk)
DE (1) DE69132329T2 (uk)
DK (1) DK0482208T3 (uk)
ES (1) ES2149761T3 (uk)
GR (1) GR3034331T3 (uk)
HU (1) HU208124B (uk)
RU (1) RU2054004C1 (uk)
TW (1) TW204348B (uk)
UA (1) UA27031A1 (uk)
WO (1) WO1991016314A1 (uk)
ZA (1) ZA913134B (uk)

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Also Published As

Publication number Publication date
HU913497D0 (en) 1992-01-28
EP0482208A1 (en) 1992-04-29
JPH07107055B1 (uk) 1995-11-15
ATE194835T1 (de) 2000-08-15
HU208124B (en) 1993-08-30
HUT60253A (en) 1992-08-28
DK0482208T3 (da) 2000-09-18
GR3034331T3 (en) 2000-12-29
US5318968A (en) 1994-06-07
ZA913134B (en) 1992-04-29
US5314883A (en) 1994-05-24
WO1991016314A1 (fr) 1991-10-31
TW204348B (uk) 1993-04-21
CA2053863A1 (en) 1991-10-26
DE69132329D1 (de) 2000-08-24
ES2149761T3 (es) 2000-11-16
AU634655B2 (en) 1993-02-25
US5202323A (en) 1993-04-13
AU7651191A (en) 1991-11-11
EP0482208B1 (en) 2000-07-19
KR970002876B1 (ko) 1997-03-12
RU2054004C1 (ru) 1996-02-10
EP0482208A4 (en) 1992-10-07
KR920701169A (ko) 1992-08-11
DE69132329T2 (de) 2000-11-30
CA2053863C (en) 1996-10-29

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