UA119046C2 - Модулятор фактора в комплемента - Google Patents
Модулятор фактора в комплемента Download PDFInfo
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- UA119046C2 UA119046C2 UAA201603969A UAA201603969A UA119046C2 UA 119046 C2 UA119046 C2 UA 119046C2 UA A201603969 A UAA201603969 A UA A201603969A UA A201603969 A UAA201603969 A UA A201603969A UA 119046 C2 UA119046 C2 UA 119046C2
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- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21047—Alternative-complement-pathway C3/C5 convertase (3.4.21.47), i.e. properdin factor B
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
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- C12N2310/31—Chemical structure of the backbone
- C12N2310/315—Phosphorothioates
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- C12N2310/30—Chemical structure
- C12N2310/32—Chemical structure of the sugar
- C12N2310/321—2'-O-R Modification
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/32—Chemical structure of the sugar
- C12N2310/323—Chemical structure of the sugar modified ring structure
- C12N2310/3231—Chemical structure of the sugar modified ring structure having an additional ring, e.g. LNA, ENA
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- C12N2310/00—Structure or type of the nucleic acid
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| US201361877624P | 2013-09-13 | 2013-09-13 | |
| PCT/US2014/055458 WO2015038939A2 (en) | 2013-09-13 | 2014-09-12 | Modulators of complement factor b |
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| UA119046C2 true UA119046C2 (uk) | 2019-04-25 |
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| RU2751847C9 (ru) | 2009-09-11 | 2021-08-20 | Ионис Фармасьютикалз, Инк. | Модуляция экспрессии гентингтина |
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| UA121656C2 (uk) * | 2014-05-01 | 2020-07-10 | Айоніс Фармасьютикалз, Інк. | Олігомерна сполука та спосіб лікування захворювання, пов'язаного з порушенням регуляції альтернативного шляху комплементу |
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-
2014
- 2014-09-12 CN CN201480056788.6A patent/CN105744959B/zh active Active
- 2014-09-12 US US15/021,651 patent/US20160222389A1/en not_active Abandoned
- 2014-09-12 HR HRP20191600 patent/HRP20191600T1/hr unknown
- 2014-09-12 AU AU2014318580A patent/AU2014318580B2/en active Active
- 2014-09-12 ES ES14844168T patent/ES2745758T3/es active Active
- 2014-09-12 LT LTEP14844168.6T patent/LT3043827T/lt unknown
- 2014-09-12 MY MYPI2016700852A patent/MY181251A/en unknown
- 2014-09-12 WO PCT/US2014/055458 patent/WO2015038939A2/en not_active Ceased
- 2014-09-12 JP JP2016542824A patent/JP6666250B2/ja active Active
- 2014-09-12 SI SI201431272T patent/SI3043827T1/sl unknown
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