UA117216C2 - Пухлиноасоційований пептид та його застосування - Google Patents
Пухлиноасоційований пептид та його застосуванняInfo
- Publication number
- UA117216C2 UA117216C2 UAA201302331A UAA201302331A UA117216C2 UA 117216 C2 UA117216 C2 UA 117216C2 UA A201302331 A UAA201302331 A UA A201302331A UA A201302331 A UAA201302331 A UA A201302331A UA 117216 C2 UA117216 C2 UA 117216C2
- Authority
- UA
- Ukraine
- Prior art keywords
- peptide
- application
- tumor associated
- cytotoxic
- associated peptide
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 108700018351 Major Histocompatibility Complex Proteins 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 231100000433 cytotoxic Toxicity 0.000 abstract 2
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 abstract 2
- 230000001472 cytotoxic effect Effects 0.000 abstract 2
- 239000013604 expression vector Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 230000020382 suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I Effects 0.000 abstract 2
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 210000004698 lymphocyte Anatomy 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/19—Dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/24—Antigen-presenting cells [APC]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/4264—Cancer antigens from embryonic or fetal origin
- A61K40/4266—Carcinoembryonic antigen [CEA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07014796 | 2007-07-27 | ||
| US95310907P | 2007-07-31 | 2007-07-31 | |
| US98124107P | 2007-10-19 | 2007-10-19 | |
| UAA201001960A UA103882C2 (uk) | 2007-07-27 | 2008-07-25 | Композиція пухлино-асоційованих пептидів та відповідна протиракова вакцина |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA117216C2 true UA117216C2 (uk) | 2018-07-10 |
Family
ID=39926464
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201302331A UA117216C2 (uk) | 2007-07-27 | 2008-07-25 | Пухлиноасоційований пептид та його застосування |
| UAA201001960A UA103882C2 (uk) | 2007-07-27 | 2008-07-25 | Композиція пухлино-асоційованих пептидів та відповідна протиракова вакцина |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201001960A UA103882C2 (uk) | 2007-07-27 | 2008-07-25 | Композиція пухлино-асоційованих пептидів та відповідна протиракова вакцина |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7994276B2 (enExample) |
| EP (2) | EP2178557B1 (enExample) |
| JP (2) | JP5352586B2 (enExample) |
| KR (1) | KR101167392B1 (enExample) |
| CN (2) | CN103360466B (enExample) |
| AU (1) | AU2008281013B2 (enExample) |
| BR (1) | BRPI0814140A2 (enExample) |
| CA (2) | CA2694771A1 (enExample) |
| DK (1) | DK2567707T3 (enExample) |
| EA (2) | EA023928B1 (enExample) |
| ES (1) | ES2608583T3 (enExample) |
| HU (1) | HUE032379T2 (enExample) |
| LT (1) | LT2567707T (enExample) |
| MX (1) | MX2010001088A (enExample) |
| NZ (1) | NZ582823A (enExample) |
| PL (1) | PL2567707T3 (enExample) |
| PT (1) | PT2567707T (enExample) |
| SI (1) | SI2567707T1 (enExample) |
| UA (2) | UA117216C2 (enExample) |
| WO (1) | WO2009015841A1 (enExample) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090004213A1 (en) | 2007-03-26 | 2009-01-01 | Immatics Biotechnologies Gmbh | Combination therapy using active immunotherapy |
| WO2009015841A1 (en) * | 2007-07-27 | 2009-02-05 | Immatics Biotechnologies Gmbh | Composition of tumour-associated peptides and related anti-cancer vaccine |
| PT2119726E (pt) * | 2008-05-14 | 2015-03-30 | Immatics Biotechnologies Gmbh | Novos e poderosos peptídeos para mhc classe ii derivados de survinina e neurocano |
| GB201004575D0 (en) * | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | Composition of tumor associated peptides and related anti cancer vaccine for the treatment of gastric cancer and other cancers |
| GB201019331D0 (en) * | 2010-03-19 | 2010-12-29 | Immatics Biotechnologies Gmbh | Methods for the diagnosis and treatment of cancer based on AVL9 |
| GB201004551D0 (en) | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer |
| GB201009222D0 (en) * | 2010-06-02 | 2010-07-21 | Immatics Biotechnologies Gmbh | Improved cancer therapy based on tumour associated antigens derived from cyclin D1 |
| GB201021289D0 (en) * | 2010-12-15 | 2011-01-26 | Immatics Biotechnologies Gmbh | Novel biomarkers for a prediction of the outcome of an immunotherapy against cancer |
| RU2633503C2 (ru) * | 2011-10-28 | 2017-10-12 | Онкотерапи Сайенс, Инк. | Пептиды торк и содержащие их вакцины |
| AU2013259598B2 (en) * | 2012-05-08 | 2018-10-04 | Western University Of Health Sciences | Standardized ex vivo platforms for the antigen-specific expansion of CD4+ T cell populations |
| GB201214007D0 (en) * | 2012-08-07 | 2012-09-19 | Scancell Ltd | Anti-tumour immune responses to modified self-epitopes |
| TWI819228B (zh) * | 2013-08-05 | 2023-10-21 | 德商伊瑪提克斯生物科技有限公司 | 新穎肽類,細胞及其用於治療多種腫瘤的用途,其製造方法及包含其等之醫藥組成物(八) |
| CN106103711A (zh) | 2013-11-21 | 2016-11-09 | 组库创世纪株式会社 | T细胞受体和b细胞受体库分析系统及其在治疗和诊断中的应用 |
| GB201501017D0 (en) * | 2014-12-23 | 2015-03-04 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers |
| JP6647315B2 (ja) | 2015-01-09 | 2020-02-14 | イーチュービクス コーポレイション | 組み合わせ免疫療法のための方法および組成物 |
| CN104630145A (zh) * | 2015-01-12 | 2015-05-20 | 杨世成 | 一种抗肿瘤t细胞、其制备方法和抗肿瘤药物 |
| GB201505585D0 (en) * | 2015-03-31 | 2015-05-13 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carinoma (RCC) and other cancers |
| TWI772927B (zh) * | 2015-03-31 | 2022-08-01 | 德商英麥提克生物技術股份有限公司 | 用於腎細胞癌(rcc)免疫治療的新型肽和肽組合物和支架 |
| EP3286213B1 (en) * | 2015-04-20 | 2021-08-04 | Etubics Corporation | Methods and compositions for combination immunotherapy |
| CN104926944B (zh) * | 2015-05-22 | 2018-04-13 | 北京康爱瑞浩生物科技股份有限公司空港分公司 | 多靶点复合抗原负载cd8+细胞毒性t淋巴细胞的制备方法及其用途 |
| NL2014935B1 (en) | 2015-06-08 | 2017-02-03 | Applied Immune Tech Ltd | T cell receptor like antibodies having fine specificity. |
| GB201511191D0 (en) * | 2015-06-25 | 2015-08-12 | Immatics Biotechnologies Gmbh | T-cell epitopes for the immunotherapy of myeloma |
| GB201511546D0 (en) * | 2015-07-01 | 2015-08-12 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers |
| MA42294B1 (fr) | 2015-07-01 | 2020-11-30 | Immatics Biotechnologies Gmbh | Nouveaux peptides et combinaison de peptides à utiliser en immunothérapie contre le cancer de l'ovaire et d'autres cancers |
| GB201512703D0 (en) | 2015-07-20 | 2015-08-26 | Scancell Ltd | Anti-tumour immune responses to modified self-epitopes |
| CN108601731A (zh) | 2015-12-16 | 2018-09-28 | 磨石肿瘤生物技术公司 | 新抗原的鉴别、制造及使用 |
| CN105586312A (zh) * | 2016-02-29 | 2016-05-18 | 时宏珍 | Hla-a0201限制性抗muc-1抗原特异性ctl的制备方法 |
| CN109922819A (zh) * | 2016-09-27 | 2019-06-21 | 西莱克塔生物科技公司 | 用于治疗癌症的重组免疫毒素 |
| EP4317432A3 (en) | 2016-12-08 | 2024-04-17 | Immatics Biotechnologies GmbH | T cell receptors with improved pairing |
| DE102016123893A1 (de) | 2016-12-08 | 2018-06-14 | Immatics Biotechnologies Gmbh | T-Zellrezeptoren mit verbesserter Bindung |
| BR112019020386A2 (pt) * | 2017-03-28 | 2020-06-09 | Mayo Found Medical Education & Res | vacinas de peptídeos de pd-1 humana e usos das mesmas |
| CN111533796A (zh) * | 2017-04-10 | 2020-08-14 | 伊玛提克斯生物技术有限公司 | 用于癌症免疫治疗的肽及其肽组合物 |
| CN111533799A (zh) * | 2017-04-10 | 2020-08-14 | 伊玛提克斯生物技术有限公司 | 用于白血病和其他癌症免疫治疗的肽和肽组合物 |
| EP4576103A3 (en) | 2017-10-10 | 2025-08-27 | Gritstone bio, Inc. | Neoantigen identification using hotspots |
| EP3714275A4 (en) | 2017-11-22 | 2021-10-27 | Gritstone bio, Inc. | REDUCTION OF JUNCTION EPITOPIC PRESENTATION FOR NEOANTIGENS |
| GB201810358D0 (en) * | 2018-06-25 | 2018-08-08 | Univ College Cardiff Consultants Ltd | Cancer-specific t-cell receptors |
| GB201815041D0 (en) | 2018-09-14 | 2018-10-31 | Scancell Ltd | Epitopes |
| CA3146298A1 (en) * | 2019-07-30 | 2021-02-04 | University Health Network | T cell receptors and methods of use thereof |
| AU2020407905A1 (en) * | 2019-12-18 | 2022-07-28 | Evaxion Biotech A/S | Nucleic acid vaccination using neo-epitope encoding constructs |
| CN111363009B (zh) * | 2020-03-18 | 2020-10-30 | 北京鼎成肽源生物技术有限公司 | 一种直肠癌靶标抗原及其刺激培养的ctl细胞及其应用 |
| CN111617238B (zh) * | 2020-06-02 | 2022-12-13 | 苏州药明康德新药开发有限公司 | 小鼠ct26结直肠癌治疗性肿瘤多肽疫苗制剂及其制备方法 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA725596A (en) | 1960-08-26 | 1966-01-11 | J. Wretlind Arvid | Method of preparing intravenously injectable fat emulsions free from side reactions or complications |
| US4897445A (en) | 1986-06-27 | 1990-01-30 | The Administrators Of The Tulane Educational Fund | Method for synthesizing a peptide containing a non-peptide bond |
| US4803261A (en) * | 1986-06-27 | 1989-02-07 | The Administrators Of The Tulane Educational Fund | Method for synthesizing a peptide containing a non-peptide |
| JPH02107189A (ja) * | 1988-05-25 | 1990-04-19 | City Of Hope | 癌胎児抗原フラグメント |
| AUPM322393A0 (en) | 1993-12-24 | 1994-01-27 | Austin Research Institute, The | Mucin carbohydrate compounds and their use in immunotherapy |
| US6096313A (en) * | 1996-02-09 | 2000-08-01 | Ludwig Institute For Cancer Research | Compositions containing immunogenic molecules and granulocyte-macrophage colony stimulating factor, as an adjuvant |
| US5849589A (en) | 1996-03-11 | 1998-12-15 | Duke University | Culturing monocytes with IL-4, TNF-α and GM-CSF TO induce differentiation to dendric cells |
| US6406705B1 (en) | 1997-03-10 | 2002-06-18 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
| US6756038B1 (en) * | 1997-10-10 | 2004-06-29 | The United States Of America As Represented By The Department Of Health And Human Services | Agonist and antagonist peptides of carcinoembryonic antigen (CEA) |
| ES2286530T3 (es) | 1997-10-10 | 2007-12-01 | The Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services | Peptidos antagonistas del antigeno carcinoembrionario (cea). |
| US6623923B1 (en) * | 1998-12-23 | 2003-09-23 | Corixa Corporation | Compounds for immunotherapy and diagnosis of colon cancer and methods for their use |
| IL125608A0 (en) | 1998-07-30 | 1999-03-12 | Yeda Res & Dev | Tumor associated antigen peptides and use of same as anti-tumor vaccines |
| AU7721500A (en) * | 1999-09-29 | 2001-04-30 | Human Genome Sciences, Inc. | Colon and colon cancer associated polynucleotides and polypeptides |
| US20030017167A1 (en) * | 2000-06-09 | 2003-01-23 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of colon cancer |
| JP2004512023A (ja) * | 2000-06-09 | 2004-04-22 | コリクサ コーポレイション | 結腸癌の治療および診断のための組成物および方法 |
| US20020102544A1 (en) * | 2000-09-15 | 2002-08-01 | David Mack | Novel methods of diagnosing colorectal cancer, compositions, and methods of screening for colorectal cancer modulators |
| CA2427858A1 (en) * | 2000-11-03 | 2002-05-10 | University Of Vermont And State Agricultural College | Compositions for inhibiting grb7 |
| CA2431313A1 (en) * | 2000-12-08 | 2002-08-01 | Eos Biotechnology, Inc. | Methods of diagnosing colorectal cancer and/or breast cancer, compositions, and methods of screening for colorectal cancer and/or breast cancer modulators |
| EP1434881A4 (en) * | 2001-09-17 | 2005-10-26 | Protein Design Labs Inc | METHOD FOR DIAGNOSIS OF CANCER COMPOSITIONS AND METHOD FOR SCREENING ON CANCER MODULATORS |
| MXPA04009554A (es) * | 2002-04-01 | 2005-01-25 | Euro Celtique Sa | Construcciones epitopes que comrpenden antigeno presentando mecanismos de marcacion celular. |
| US20030211477A1 (en) * | 2002-04-05 | 2003-11-13 | Holmes Kathryn V. | Carcinoembryonic antigen cell adhesion molecule 1 (CEACAM1) structure and uses thereof in drug identification and screening |
| AU2002368151A1 (en) * | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | Matrix metalloproteinase inhibitors and methods for identification of lead compounds |
| DE602004015064D1 (de) * | 2003-01-06 | 2008-08-28 | Wyeth Corp | Zusammensetzungen und verfahren zur diagnose und behandlung von kolonkrebs |
| JP2007523610A (ja) * | 2003-05-05 | 2007-08-23 | イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー | 癌胎児抗原をコードする合成遺伝子およびその使用 |
| CN1727362B (zh) * | 2004-07-30 | 2010-12-01 | 中国人民解放军第二军医大学 | 癌胚抗原阳性肿瘤治疗性疫苗的制备及应用 |
| US20080254031A1 (en) * | 2004-09-09 | 2008-10-16 | Exonhit Therapeutics Sa | Tumor Specific Genes and Variant Rnas and Uses Thereof as Targets for Cancer Therapy and Diagnosis |
| DE602004019215D1 (de) * | 2004-10-02 | 2009-03-12 | Immatics Biotechnologies Gmbh | Immunogene T-Helfer Epitope von menschlichen Tumorantigenen und deren Verwendung in immunotherapeutischen Methoden |
| ITRM20050064A1 (it) * | 2005-02-16 | 2006-08-17 | Univ Siena | Peptide poliepitopico derivato dalla timidilato sintetasi avente attivita' immunologica e antitumorale e composizioni farmaceutiche relative. |
| EP1717245B1 (en) * | 2005-04-26 | 2011-06-08 | Immatics Biotechnologies GmbH | T-cell epitopes from the oncofetal antigen-immature laminin receptor protein and medical uses thereof |
| PL1760089T3 (pl) * | 2005-09-05 | 2010-03-31 | Immatics Biotechnologies Gmbh | Peptydy towarzyszące nowotworom, wiążące się z cząsteczkami klasy I i II antygenów ludzkich leukocytów (HLA) i związana z nimi szczepionka przeciwnowotworowa |
| PL1760088T3 (pl) | 2005-09-05 | 2008-10-31 | Immatics Biotechnologies Gmbh | Związane z nowotworem peptydy wiążące się w sposób niedyskryminujący z cząsteczkami antygenu ludzkiego leukocytu klasy II (HLA) |
| US8298544B2 (en) * | 2006-02-27 | 2012-10-30 | Gal Markel | CEACAM based antibacterial agents |
| WO2009015841A1 (en) * | 2007-07-27 | 2009-02-05 | Immatics Biotechnologies Gmbh | Composition of tumour-associated peptides and related anti-cancer vaccine |
| WO2009117656A2 (en) * | 2008-03-21 | 2009-09-24 | Vectorlogics,Inc. | Capsid-incorporated antigen for novel adenovirus vaccine |
| PT2119726E (pt) * | 2008-05-14 | 2015-03-30 | Immatics Biotechnologies Gmbh | Novos e poderosos peptídeos para mhc classe ii derivados de survinina e neurocano |
-
2008
- 2008-07-25 WO PCT/EP2008/006152 patent/WO2009015841A1/en not_active Ceased
- 2008-07-25 CN CN201310109229.4A patent/CN103360466B/zh not_active Expired - Fee Related
- 2008-07-25 KR KR1020107001771A patent/KR101167392B1/ko not_active Expired - Fee Related
- 2008-07-25 MX MX2010001088A patent/MX2010001088A/es active IP Right Grant
- 2008-07-25 SI SI200831735A patent/SI2567707T1/sl unknown
- 2008-07-25 BR BRPI0814140A patent/BRPI0814140A2/pt not_active IP Right Cessation
- 2008-07-25 EA EA201300322A patent/EA023928B1/ru not_active IP Right Cessation
- 2008-07-25 NZ NZ582823A patent/NZ582823A/en not_active IP Right Cessation
- 2008-07-25 PL PL12187307T patent/PL2567707T3/pl unknown
- 2008-07-25 US US12/180,113 patent/US7994276B2/en active Active
- 2008-07-25 HU HUE12187307A patent/HUE032379T2/en unknown
- 2008-07-25 EA EA201000208A patent/EA018457B1/ru not_active IP Right Cessation
- 2008-07-25 AU AU2008281013A patent/AU2008281013B2/en not_active Ceased
- 2008-07-25 CN CN200880100807.5A patent/CN101765434B/zh not_active Expired - Fee Related
- 2008-07-25 LT LTEP12187307.9T patent/LT2567707T/lt unknown
- 2008-07-25 CA CA2694771A patent/CA2694771A1/en not_active Abandoned
- 2008-07-25 EP EP08785105.1A patent/EP2178557B1/en active Active
- 2008-07-25 PT PT121873079T patent/PT2567707T/pt unknown
- 2008-07-25 UA UAA201302331A patent/UA117216C2/uk unknown
- 2008-07-25 CA CA2817054A patent/CA2817054C/en not_active Expired - Fee Related
- 2008-07-25 UA UAA201001960A patent/UA103882C2/uk unknown
- 2008-07-25 EP EP12187307.9A patent/EP2567707B1/en active Active
- 2008-07-25 JP JP2010517324A patent/JP5352586B2/ja not_active Expired - Fee Related
- 2008-07-25 DK DK12187307.9T patent/DK2567707T3/da active
- 2008-07-25 ES ES12187307.9T patent/ES2608583T3/es active Active
-
2013
- 2013-03-25 JP JP2013061688A patent/JP5746251B2/ja not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| UA117216C2 (uk) | Пухлиноасоційований пептид та його застосування | |
| TN2015000177A1 (en) | Anti-ceacam5 antibodies and uses thereof | |
| BR112012025568A2 (pt) | proteínas de ligação ao tnf-<244>. | |
| UA113712C2 (xx) | Антитіло до fap і способи його застосування | |
| BR112012013736A2 (pt) | processo para intesificação de terapia com anticorpos antitumor | |
| MX2010005022A (es) | Anticuerpos que unen celulas dendriticas y epiteliales 205 (dec-205) humanas. | |
| UA98295C2 (ru) | Опухолево-ассоциированный пептид, который неспецифически связывается с молекулами ii класса лейкоцитарного антигена человека (hla) | |
| UA103751C2 (ru) | Иммуногенный пептид для иммунотерапии | |
| MX2009005189A (es) | Anticuerpos humanos monoclonales para btla y metodos de uso. | |
| MY158219A (en) | Method for activation of helper t cell and composition for use in the method | |
| WO2012044999A3 (en) | Reversible protein multimers, methods for their production and use | |
| UA118332C2 (uk) | Білок, що зв'язує антиген cd27l | |
| MX2010005830A (es) | Conjugado de anticuerpo monoclonal anti-b7h4 - farmaco y metodos de uso del mismo. | |
| CY1119410T1 (el) | Βελτιστοποιημενα μονοκλωνικα αντισωματα εναντι του αναστολεα της οδου του ιστικου παραγοντα (tfpi) | |
| MX2014009628A (es) | Uniones a cdim y sus usos. | |
| CY1117326T1 (el) | Παραγωγο κατεχολαμινης χρησιμο για τη θεραπεια ασθενειας parkinson | |
| DK2027152T3 (da) | Peptidfragmenter til induktion af syntese af ekstracellulære matrixproteiner | |
| MY177970A (en) | Bcma (cd269/tnfrsf17) -binding proteins | |
| WO2010132389A3 (en) | Methods for treating cancers and diseases associated with 4-1bb (cd137) expression | |
| PH12013502192A1 (en) | Antibodies against human angiopoietin 2 | |
| EA200870615A1 (ru) | Производные лептомицина | |
| MX2011010673A (es) | Formulaciones de nanoparticulas y usos de las mismas. | |
| UA115122C2 (uk) | Cd3-зв'язувальна молекула, здатна до зв'язування з cd3 людини і cd3, що не є людським | |
| MY150246A (en) | Alpha 5 - beta 1 antibodies and their uses | |
| PH12012501545B1 (en) | Antibody drug conjugates (adc) that bind to 161p2f10b proteins |