UA112763C2 - Алелі 1-дезокси-d-ксилулозо-5-фосфатсинтази, відповідальні за посилений біосинтез терпенів - Google Patents

Алелі 1-дезокси-d-ксилулозо-5-фосфатсинтази, відповідальні за посилений біосинтез терпенів

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Publication number
UA112763C2
UA112763C2 UAA201306199A UAA201306199A UA112763C2 UA 112763 C2 UA112763 C2 UA 112763C2 UA A201306199 A UAA201306199 A UA A201306199A UA A201306199 A UAA201306199 A UA A201306199A UA 112763 C2 UA112763 C2 UA 112763C2
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UA
Ukraine
Prior art keywords
xylulose
deoxy
phosphate synthase
terpene biosynthesis
dxs
Prior art date
Application number
UAA201306199A
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English (en)
Inventor
Філіпп Южюене
Филипп Южюене
Ерік Дюшен
Эрик Дюлен
Дідьє Мердіноглю
Дидье Мердиноглю
Original Assignee
Геноплант-Валор
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Геноплант-Валор filed Critical Геноплант-Валор
Publication of UA112763C2 publication Critical patent/UA112763C2/uk

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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H6/00—Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
    • A01H6/20—Brassicaceae, e.g. canola, broccoli or rucola
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H6/00—Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
    • A01H6/82—Solanaceae, e.g. pepper, tobacco, potato, tomato or eggplant
    • A01H6/823—Nicotiana, e.g. tobacco
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H6/00—Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
    • A01H6/88—Vitaceae, e.g. Vitus [grape]
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8274—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for herbicide resistance
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    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
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    • C12Y—ENZYMES
    • C12Y202/00—Transferases transferring aldehyde or ketonic groups (2.2)
    • C12Y202/01—Transketolases and transaldolases (2.2.1)
    • C12Y202/01007—1-Deoxy-D-xylulose-5-phosphate synthase (2.2.1.7)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
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  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Medicinal Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Environmental Sciences (AREA)
  • Botany (AREA)
  • Physiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)

Abstract

Винахід належить до мутованого виділеного поліпептиду, що має підвищену активність DXS та стосується способу посилення активності поліпептиду 1-дезокси-D-ксилулозо-5-фосфатсинтази (DXS) бактерій з метою збільшення продукування терпенів у клітинах, способу підвищення виробництва терпенів у клітині-хазяїні, що містить посилений фермент DXS, клітини-хазяїна, що експресують цей поліпептид.
UAA201306199A 2010-10-20 2011-10-20 Алелі 1-дезокси-d-ксилулозо-5-фосфатсинтази, відповідальні за посилений біосинтез терпенів UA112763C2 (uk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10013809A EP2444415A1 (en) 2010-10-20 2010-10-20 1-Deoxy-D-xylulose 5-phosphate synthase alleles responsible for enhanced terpene biosynthesis
EP11003842A EP2444416A1 (en) 2010-10-20 2011-05-10 1-deoxy-D-xylulose 5-phosphate synthase alleles responsible for enhanced terpene biosynthesis
PCT/EP2011/005283 WO2012052171A1 (en) 2010-10-20 2011-10-20 1-deoxy-d-xylulose 5-phosphate synthase alleles responsible for enhanced terpene biosynthesis

Publications (1)

Publication Number Publication Date
UA112763C2 true UA112763C2 (uk) 2016-10-25

Family

ID=43513606

Family Applications (1)

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UAA201306199A UA112763C2 (uk) 2010-10-20 2011-10-20 Алелі 1-дезокси-d-ксилулозо-5-фосфатсинтази, відповідальні за посилений біосинтез терпенів

Country Status (13)

Country Link
US (1) US9556424B2 (uk)
EP (3) EP2444415A1 (uk)
JP (2) JP6327856B2 (uk)
KR (1) KR101878899B1 (uk)
CN (1) CN103429612B (uk)
AU (1) AU2011317859B2 (uk)
BR (1) BR112013009807A2 (uk)
CA (1) CA2815264A1 (uk)
DK (1) DK2630157T3 (uk)
EA (1) EA028761B1 (uk)
UA (1) UA112763C2 (uk)
WO (1) WO2012052171A1 (uk)
ZA (1) ZA201302751B (uk)

Families Citing this family (13)

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Publication number Priority date Publication date Assignee Title
EP2444415A1 (en) * 2010-10-20 2012-04-25 Genoplante-Valor 1-Deoxy-D-xylulose 5-phosphate synthase alleles responsible for enhanced terpene biosynthesis
JP2015516173A (ja) * 2012-05-16 2015-06-11 グリコス バイオテクノロジーズ インコーポレイテッドＧｌｙｃｏｓ Ｂｉｏｔｅｃｈｎｏｌｏｇｉｅｓ， Ｉｎｃ． イソプレン生産用微生物およびプロセス
JP6983512B2 (ja) * 2014-06-13 2021-12-17 ディノベDeinove テルペン又はテルペノイドを産生する方法
CN107406836A (zh) * 2014-12-29 2017-11-28 富优基尼以色列股份有限公司 核酸构造、含有核酸构造的植物以及将核酸构造用于提高植物抗病虫害和改良植物单萜特性的用途
CN106148295A (zh) * 2015-04-15 2016-11-23 中国科学院微生物研究所 1-脱氧-d-木酮糖-5-磷酸合成酶及其编码基因与应用
JP6357186B2 (ja) * 2016-03-31 2018-07-11 Ｊｘｔｇエネルギー株式会社 カロテノイドの製造方法
US20190345520A1 (en) 2016-12-16 2019-11-14 Deinove Methods of producing phytoene
JP2021505154A (ja) 2017-12-07 2021-02-18 ザイマージェン インコーポレイテッド 発酵によって（６ｅ）−８−ヒドロキシゲラニオールを生産するための設計された生合成経路
EP3728212A1 (en) 2017-12-21 2020-10-28 Zymergen Inc. Nepetalactol oxidoreductases, nepetalactol synthases, and microbes capable of producing nepetalactone
CA3108798A1 (en) * 2018-08-08 2020-02-13 Board Of Trustees Of Michigan State University Improved production of terpenoids using enzymes anchored to lipid droplet surface proteins
WO2020046215A1 (en) * 2018-08-31 2020-03-05 Agency For Science, Technology And Research Methods for terpenoid production
US20230125534A1 (en) * 2019-11-04 2023-04-27 Agriculture Victoria Services Pty Ltd A Method to Produce Targeted Gene Editing Constructs
CN114107549A (zh) * 2021-12-14 2022-03-01 北京市林业果树科学研究院 一种与葡萄果实玫瑰香味相关的kasp分子标记与应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU746684B2 (en) * 1997-09-02 2002-05-02 Washington State University Research Foundation Nucleic and amino acid sequences for a novel transketolase from $i (Mentha Piperita)
DE19831570A1 (de) * 1998-07-14 2000-01-20 Siemens Ag Biometrischer Sensor und Verfahren zu dessen Herstellung
GB9901902D0 (en) * 1999-01-28 1999-03-17 New Royal Holloway & Bedford Manipulating isoprenoid expression
ZA200800889B (en) * 2005-07-05 2009-09-30 Univ California Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof
JP5035872B2 (ja) * 2005-09-16 2012-09-26 株式会社ブリヂストン パラゴムノキの非メバロン酸経路でのイソペンテニル二リン酸生合成に関与する遺伝子群
EP1987147B1 (en) * 2006-02-14 2010-07-28 Firmenich S.A. Method for producing terpenes and mep-transformed microorganisms therefore
US8173410B2 (en) * 2008-04-23 2012-05-08 Danisco Us Inc. Isoprene synthase variants for improved microbial production of isoprene
EP2444415A1 (en) * 2010-10-20 2012-04-25 Genoplante-Valor 1-Deoxy-D-xylulose 5-phosphate synthase alleles responsible for enhanced terpene biosynthesis

Also Published As

Publication number Publication date
AU2011317859A1 (en) 2013-05-23
US20130276166A1 (en) 2013-10-17
JP6327856B2 (ja) 2018-05-23
KR101878899B1 (ko) 2018-08-17
US9556424B2 (en) 2017-01-31
EA201390592A1 (ru) 2014-01-30
AU2011317859B2 (en) 2015-07-16
EA028761B1 (ru) 2017-12-29
WO2012052171A1 (en) 2012-04-26
JP2017060512A (ja) 2017-03-30
EP2444416A1 (en) 2012-04-25
BR112013009807A2 (pt) 2021-06-29
EP2444415A1 (en) 2012-04-25
JP2014500710A (ja) 2014-01-16
CN103429612A (zh) 2013-12-04
CN103429612B (zh) 2016-08-10
ZA201302751B (en) 2014-09-25
DK2630157T3 (en) 2018-04-30
EP2630157B1 (en) 2018-01-24
CA2815264A1 (en) 2012-04-26
KR20140032947A (ko) 2014-03-17
EP2630157A1 (en) 2013-08-28

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