TWI859138B - 與抗cd19抗體藥物結合物相關之組合物及方法 - Google Patents

與抗cd19抗體藥物結合物相關之組合物及方法 Download PDF

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TWI859138B
TWI859138B TW108116030A TW108116030A TWI859138B TW I859138 B TWI859138 B TW I859138B TW 108116030 A TW108116030 A TW 108116030A TW 108116030 A TW108116030 A TW 108116030A TW I859138 B TWI859138 B TW I859138B
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Taiwan
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amino acid
pharmaceutically acceptable
seq
acceptable salt
acid sequence
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TW108116030A
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Chinese (zh)
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TW202000239A (zh
Inventor
宋昊永
朴允姬
金星民
金炯來
吳智惠
柳賢敏
蔡濟旭
吳英秀
金容柱
毛林 迪漢
尼可拉斯 費雪
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韓商瑞嘉化學生物科學股份有限公司
瑞士商諾夫益慕恩公司
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    • A—HUMAN NECESSITIES
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
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  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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TW108116030A 2018-05-09 2019-05-09 與抗cd19抗體藥物結合物相關之組合物及方法 TWI859138B (zh)

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US201862669183P 2018-05-09 2018-05-09
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EP (1) EP3790591A4 (enExample)
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KR (1) KR20210023839A (enExample)
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CN107847605B (zh) 2015-11-25 2021-12-24 乐高化学生物科学股份有限公司 包含分支接头的抗体-药物缀合物及其相关方法
JP7120765B2 (ja) 2015-11-25 2022-08-17 レゴケム バイオサイエンシズ， インク． ペプチド基を含む複合体及びそれに関連する方法
HUE067016T2 (hu) 2015-11-25 2024-09-28 Ligachem Biosciences Inc Önfeláldozó csoportokat tartalmazó konjugátumok és ezekkel kapcsolos eljárások
JP7664680B2 (ja) 2017-03-29 2025-04-18 リガケム バイオサイエンシズ， インク． ピロロベンゾジアゼピン二量体前駆体及びそのリガンド－リンカーコンジュゲート化合物
US11827703B2 (en) * 2018-05-09 2023-11-28 Legochem Biosciences, Inc. Compositions and methods related to anti-CD19 antibody drug conjugates
CN113811549A (zh) 2019-02-21 2021-12-17 Xencor股份有限公司 非靶向和靶向性il-10 fc融合蛋白
KR20210028544A (ko) 2019-09-04 2021-03-12 주식회사 레고켐 바이오사이언스 인간 ror1에 대한 항체를 포함하는 항체 약물 접합체 및 이의 용도
TW202136287A (zh) 2019-12-17 2021-10-01 法商Ｏｓｅ免疫治療公司 包含il-7變體之雙官能分子
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