TWI824258B - 包含il-2蛋白及cd80蛋白之融合蛋白及其用途 - Google Patents
包含il-2蛋白及cd80蛋白之融合蛋白及其用途 Download PDFInfo
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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| US11492384B2 (en) * | 2018-09-17 | 2022-11-08 | Gi Innovation, Inc. | Fusion protein comprising IL-2 protein and CD80 protein, and use thereof |
| JP7543404B2 (ja) | 2019-11-20 | 2024-09-02 | ジーアイ・セル・インコーポレイテッド | Ｔ細胞培養用培地組成物及びこれを用いたｔ細胞の培養方法 |
| RS66373B1 (sr) | 2019-11-20 | 2025-02-28 | Gi Cell Inc | Sastav za kultivaciju prirodnih ćelija ubica i postupak za pripremu prirodnih ćelija ubica njegovim korišćenjem |
| US20230014358A1 (en) * | 2019-11-27 | 2023-01-19 | Gi Cell, Inc. | Composition for anticancer treatment, comprising nk cells and fusion protein which comprises il-2 protein and cd80 protein |
| AU2020391280B2 (en) * | 2019-11-27 | 2024-06-06 | Gi Cell, Inc. | Composition for anticancer treatment, comprising NK cells and fusion protein which comprises IL-2 protein and CD80 protein |
| ES3040184T3 (en) | 2020-03-18 | 2025-10-29 | Gi Innovation Inc | Fusion protein preparation comprising il-2 and cd80 proteins |
| TWI855242B (zh) * | 2020-03-18 | 2024-09-11 | 南韓商Ｇｉ醫諾微新股份有限公司 | 包含含有il-2蛋白與cd80蛋白之融合蛋白及抗癌藥物的用於治療癌症的藥學組成物 |
| WO2021187904A1 (ko) * | 2020-03-18 | 2021-09-23 | (주)지아이이노베이션 | Il-2 단백질 및 cd80 단백질 단편 또는 이의 변이체를 포함하는 융합단백질 및 이의 용도 |
| WO2021201615A1 (ko) * | 2020-03-31 | 2021-10-07 | 한미약품 주식회사 | 신규한 면역 활성 인터루킨 2 아날로그 |
| WO2021238904A1 (zh) * | 2020-05-25 | 2021-12-02 | 北京比洋生物技术有限公司 | Fc-CD80融合蛋白和其缀合物以及它们的用途 |
| KR102373965B1 (ko) * | 2020-06-05 | 2022-03-15 | (주)지아이이노베이션 | Ｉｌ-２ 단백질 및 ｃｄ８０ 단백질을 포함하는 융합단백질을 포함하는 방사선 치료 증진용 약학적 조성물 |
| KR102313505B1 (ko) * | 2020-06-30 | 2021-10-18 | (주)지아이이노베이션 | 항-lag-3 항체 및 il-2를 포함하는 융합단백질 및 이의 용도 |
| TW202216745A (zh) * | 2020-07-02 | 2022-05-01 | 美商英伊布里克斯公司 | 包含經修飾ｉｌ－２多肽之多肽及其用途 |
| WO2022045849A1 (ko) * | 2020-08-31 | 2022-03-03 | 주식회사 지아이셀 | Il15 단백질, il15 수용체 알파 단백질, fc 도메인 및 il2 단백질을 포함하는 융합단백질 및 이의 용도 |
| TWI815194B (zh) | 2020-10-22 | 2023-09-11 | 美商基利科學股份有限公司 | 介白素2-Fc融合蛋白及使用方法 |
| EP4259648A4 (en) * | 2020-12-08 | 2025-03-26 | Seattle Children's Hospital (DBA Seattle Children's Research Institute) | Chimeric anti-EGFR antigen receptors |
| IL305758A (en) * | 2021-03-10 | 2023-11-01 | Immunowake Inc | Immunomodulatory compounds and their uses |
| WO2022057696A2 (zh) * | 2021-09-08 | 2022-03-24 | 中南大学湘雅医院 | 一种重组蛋白的编码序列、重组蛋白及其单克隆抗体的制备方法 |
| WO2023234743A1 (ko) * | 2022-06-03 | 2023-12-07 | (주)지아이이노베이션 | 항-tigit 항체를 포함하는 이중 특이적 항체 및 이의 용도 |
| WO2023249425A1 (ko) * | 2022-06-22 | 2023-12-28 | ㈜지아이이노베이션 | 항-cd73 항체 및 il-2를 포함하는 융합단백질 및 이의 용도 |
| EP4591873A4 (en) * | 2022-09-20 | 2026-02-25 | Gi Biome Inc | Polytherapy including a strain of Lactobacillus plantarum and a cancer treatment method using it |
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