JP7085644B2 - Ｉｌ－２タンパク質およびｃｄ８０タンパク質を含む融合タンパク質およびその使用 - Google Patents

Ｉｌ－２タンパク質およびｃｄ８０タンパク質を含む融合タンパク質およびその使用 Download PDF

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JP7085644B2
JP7085644B2 JP2020562067A JP2020562067A JP7085644B2 JP 7085644 B2 JP7085644 B2 JP 7085644B2 JP 2020562067 A JP2020562067 A JP 2020562067A JP 2020562067 A JP2020562067 A JP 2020562067A JP 7085644 B2 JP7085644 B2 JP 7085644B2
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JP2021511081A (ja
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チャン・ミョンホ
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GI Innovation Inc
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70532—B7 molecules, e.g. CD80, CD86
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    • C12N15/09—Recombinant DNA-technology
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    • C12N5/0602—Vertebrate cells
    • C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
    • C12N5/0682—Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
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    • C12N2800/00—Nucleic acids vectors
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JP2020562067A 2018-09-17 2019-09-16 Ｉｌ－２タンパク質およびｃｄ８０タンパク質を含む融合タンパク質およびその使用 Active JP7085644B2 (ja)

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JP2022070213A JP7569820B2 (ja) 2018-09-17 2022-04-21 Ｉｌ－２タンパク質およびｃｄ８０タンパク質を含む融合タンパク質およびその使用

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Application Number Priority Date Filing Date Title
KR10-2018-0110698 2018-09-17
KR20180110698 2018-09-17
KR10-2019-0001867 2019-01-07
KR20190001867 2019-01-07
US201962832013P 2019-04-10 2019-04-10
US62/832,013 2019-04-10
KR20190053436 2019-05-08
KR10-2019-0053436 2019-05-08
PCT/KR2019/011928 WO2020060122A1 (ko) 2018-09-17 2019-09-16 Il-2 단백질 및 cd80 단백질을 포함하는 융합단백질 및 이의 용도

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JP2022070213A Division JP7569820B2 (ja) 2018-09-17 2022-04-21 Ｉｌ－２タンパク質およびｃｄ８０タンパク質を含む融合タンパク質およびその使用

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JP7085644B2 true JP7085644B2 (ja) 2022-06-16

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JP2022070213A Active JP7569820B2 (ja) 2018-09-17 2022-04-21 Ｉｌ－２タンパク質およびｃｄ８０タンパク質を含む融合タンパク質およびその使用

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CN (2) CN118725141A (https=)
AU (1) AU2019343850B2 (https=)
CA (1) CA3086486A1 (https=)
CL (1) CL2020001872A1 (https=)
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TW (2) TWI824258B (https=)
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Cited By (1)

* Cited by examiner, † Cited by third party
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JP2022115876A (ja) * 2018-09-17 2022-08-09 ジーアイ・イノベイション・インコーポレイテッド Ｉｌ－２タンパク質およびｃｄ８０タンパク質を含む融合タンパク質およびその使用

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KR102379464B1 (ko) * 2016-06-20 2022-03-29 키맵 리미티드 항-pd-l1 항체
JP7543404B2 (ja) 2019-11-20 2024-09-02 ジーアイ・セル・インコーポレイテッド Ｔ細胞培養用培地組成物及びこれを用いたｔ細胞の培養方法
RS66373B1 (sr) 2019-11-20 2025-02-28 Gi Cell Inc Sastav za kultivaciju prirodnih ćelija ubica i postupak za pripremu prirodnih ćelija ubica njegovim korišćenjem
US20230014358A1 (en) * 2019-11-27 2023-01-19 Gi Cell, Inc. Composition for anticancer treatment, comprising nk cells and fusion protein which comprises il-2 protein and cd80 protein
AU2020391280B2 (en) * 2019-11-27 2024-06-06 Gi Cell, Inc. Composition for anticancer treatment, comprising NK cells and fusion protein which comprises IL-2 protein and CD80 protein
ES3040184T3 (en) 2020-03-18 2025-10-29 Gi Innovation Inc Fusion protein preparation comprising il-2 and cd80 proteins
TWI855242B (zh) * 2020-03-18 2024-09-11 南韓商Ｇｉ醫諾微新股份有限公司 包含含有il-2蛋白與cd80蛋白之融合蛋白及抗癌藥物的用於治療癌症的藥學組成物
WO2021187904A1 (ko) * 2020-03-18 2021-09-23 (주)지아이이노베이션 Il-2 단백질 및 cd80 단백질 단편 또는 이의 변이체를 포함하는 융합단백질 및 이의 용도
WO2021201615A1 (ko) * 2020-03-31 2021-10-07 한미약품 주식회사 신규한 면역 활성 인터루킨 2 아날로그
WO2021238904A1 (zh) * 2020-05-25 2021-12-02 北京比洋生物技术有限公司 Fc-CD80融合蛋白和其缀合物以及它们的用途
KR102373965B1 (ko) * 2020-06-05 2022-03-15 (주)지아이이노베이션 Ｉｌ-２ 단백질 및 ｃｄ８０ 단백질을 포함하는 융합단백질을 포함하는 방사선 치료 증진용 약학적 조성물
KR102313505B1 (ko) * 2020-06-30 2021-10-18 (주)지아이이노베이션 항-lag-3 항체 및 il-2를 포함하는 융합단백질 및 이의 용도
TW202216745A (zh) * 2020-07-02 2022-05-01 美商英伊布里克斯公司 包含經修飾ｉｌ－２多肽之多肽及其用途
WO2022045849A1 (ko) * 2020-08-31 2022-03-03 주식회사 지아이셀 Il15 단백질, il15 수용체 알파 단백질, fc 도메인 및 il2 단백질을 포함하는 융합단백질 및 이의 용도
TWI815194B (zh) 2020-10-22 2023-09-11 美商基利科學股份有限公司 介白素2-Fc融合蛋白及使用方法
EP4259648A4 (en) * 2020-12-08 2025-03-26 Seattle Children's Hospital (DBA Seattle Children's Research Institute) Chimeric anti-EGFR antigen receptors
IL305758A (en) * 2021-03-10 2023-11-01 Immunowake Inc Immunomodulatory compounds and their uses
WO2022057696A2 (zh) * 2021-09-08 2022-03-24 中南大学湘雅医院 一种重组蛋白的编码序列、重组蛋白及其单克隆抗体的制备方法
WO2023234743A1 (ko) * 2022-06-03 2023-12-07 (주)지아이이노베이션 항-tigit 항체를 포함하는 이중 특이적 항체 및 이의 용도
WO2023249425A1 (ko) * 2022-06-22 2023-12-28 ㈜지아이이노베이션 항-cd73 항체 및 il-2를 포함하는 융합단백질 및 이의 용도
EP4591873A4 (en) * 2022-09-20 2026-02-25 Gi Biome Inc Polytherapy including a strain of Lactobacillus plantarum and a cancer treatment method using it
WO2024063546A1 (ko) 2022-09-20 2024-03-28 주식회사 지아이바이옴 락토바실러스 플란타룸 균주의 병용 요법 및 이를 이용한 암 치료 방법
CN115850436B (zh) * 2022-10-14 2026-02-03 海徕科(北京)生物技术有限公司 白介素2突变体及其应用
WO2025063755A1 (ko) * 2023-09-20 2025-03-27 주식회사 에스엘바이젠 항암 dna 백신 및 면역반응-증진용 융합단백질을 포함하는 신규 암 치료제

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JP2022115876A (ja) * 2018-09-17 2022-08-09 ジーアイ・イノベイション・インコーポレイテッド Ｉｌ－２タンパク質およびｃｄ８０タンパク質を含む融合タンパク質およびその使用
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