TWI755498B - 自動化製備生物樣本之系統及方法 - Google Patents
自動化製備生物樣本之系統及方法 Download PDFInfo
- Publication number
- TWI755498B TWI755498B TW107108177A TW107108177A TWI755498B TW I755498 B TWI755498 B TW I755498B TW 107108177 A TW107108177 A TW 107108177A TW 107108177 A TW107108177 A TW 107108177A TW I755498 B TWI755498 B TW I755498B
- Authority
- TW
- Taiwan
- Prior art keywords
- pipette tip
- tool head
- sample
- sample container
- axis
- Prior art date
Links
- 238000000034 method Methods 0.000 title description 47
- 238000002360 preparation method Methods 0.000 title description 5
- 238000012546 transfer Methods 0.000 claims abstract description 65
- 238000012545 processing Methods 0.000 claims abstract description 64
- 238000013519 translation Methods 0.000 claims abstract description 45
- 239000002699 waste material Substances 0.000 claims description 40
- 238000002955 isolation Methods 0.000 claims description 20
- 238000011068 loading method Methods 0.000 claims description 20
- 239000007788 liquid Substances 0.000 claims description 18
- 230000033001 locomotion Effects 0.000 claims description 18
- 239000003153 chemical reaction reagent Substances 0.000 claims description 15
- 239000011521 glass Substances 0.000 claims description 14
- 230000000153 supplemental effect Effects 0.000 claims description 10
- 238000004891 communication Methods 0.000 claims description 8
- 230000000717 retained effect Effects 0.000 claims description 6
- 230000014759 maintenance of location Effects 0.000 claims description 3
- 230000014616 translation Effects 0.000 claims 26
- 239000012530 fluid Substances 0.000 abstract description 22
- 239000000523 sample Substances 0.000 description 342
- 239000012528 membrane Substances 0.000 description 22
- 238000012360 testing method Methods 0.000 description 17
- 239000000834 fixative Substances 0.000 description 16
- 241000701806 Human papillomavirus Species 0.000 description 10
- 239000013610 patient sample Substances 0.000 description 10
- 239000012472 biological sample Substances 0.000 description 9
- 206010008263 Cervical dysplasia Diseases 0.000 description 7
- 238000009826 distribution Methods 0.000 description 6
- 238000003860 storage Methods 0.000 description 6
- 208000007879 Atypical Squamous Cells of the Cervix Diseases 0.000 description 5
- 230000002159 abnormal effect Effects 0.000 description 5
- 238000011109 contamination Methods 0.000 description 5
- 208000032124 Squamous Intraepithelial Lesions Diseases 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 4
- 238000012864 cross contamination Methods 0.000 description 4
- 239000010410 layer Substances 0.000 description 4
- 238000009595 pap smear Methods 0.000 description 4
- 238000001507 sample dispersion Methods 0.000 description 4
- 208000019802 Sexually transmitted disease Diseases 0.000 description 3
- 230000003213 activating effect Effects 0.000 description 3
- 230000002380 cytological effect Effects 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 238000002156 mixing Methods 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 230000002441 reversible effect Effects 0.000 description 3
- 239000002356 single layer Substances 0.000 description 3
- 206010008342 Cervix carcinoma Diseases 0.000 description 2
- 241000606153 Chlamydia trachomatis Species 0.000 description 2
- 241000588652 Neisseria gonorrhoeae Species 0.000 description 2
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 description 2
- 238000011166 aliquoting Methods 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 238000001574 biopsy Methods 0.000 description 2
- 201000010881 cervical cancer Diseases 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 229940038705 chlamydia trachomatis Drugs 0.000 description 2
- 239000006185 dispersion Substances 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 238000003384 imaging method Methods 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 239000003755 preservative agent Substances 0.000 description 2
- 230000002335 preservative effect Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 238000011179 visual inspection Methods 0.000 description 2
- 229920001621 AMOLED Polymers 0.000 description 1
- 208000009956 adenocarcinoma Diseases 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 210000003679 cervix uteri Anatomy 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 229920001940 conductive polymer Polymers 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 210000004907 gland Anatomy 0.000 description 1
- 230000000762 glandular Effects 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 201000004933 in situ carcinoma Diseases 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 239000004973 liquid crystal related substance Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000013618 particulate matter Substances 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 238000007790 scraping Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 125000006850 spacer group Chemical group 0.000 description 1
- 206010041823 squamous cell carcinoma Diseases 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 210000000115 thoracic cavity Anatomy 0.000 description 1
- 238000010200 validation analysis Methods 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 235000001892 vitamin D2 Nutrition 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1011—Control of the position or alignment of the transfer device
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
- G01N1/312—Apparatus therefor for samples mounted on planar substrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00871—Communications between instruments or with remote terminals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N2035/00039—Transport arrangements specific to flat sample substrates, e.g. pusher blade
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N2035/00099—Characterised by type of test elements
- G01N2035/00138—Slides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
- G01N2035/0401—Sample carriers, cuvettes or reaction vessels
- G01N2035/0403—Sample carriers with closing or sealing means
- G01N2035/0405—Sample carriers with closing or sealing means manipulating closing or opening means, e.g. stoppers, screw caps, lids or covers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
- G01N2035/0401—Sample carriers, cuvettes or reaction vessels
- G01N2035/0406—Individual bottles or tubes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/103—General features of the devices using disposable tips
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1032—Dilution or aliquotting
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Robotics (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201715454819A | 2017-03-09 | 2017-03-09 | |
| US15/454,819 | 2017-03-09 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW201842317A TW201842317A (zh) | 2018-12-01 |
| TWI755498B true TWI755498B (zh) | 2022-02-21 |
Family
ID=61837834
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW107108177A TWI755498B (zh) | 2017-03-09 | 2018-03-09 | 自動化製備生物樣本之系統及方法 |
| TW111101663A TWI792862B (zh) | 2017-03-09 | 2018-03-09 | 自動化製備生物樣本之方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW111101663A TWI792862B (zh) | 2017-03-09 | 2018-03-09 | 自動化製備生物樣本之方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US10900875B2 (enExample) |
| JP (5) | JP6934061B2 (enExample) |
| KR (5) | KR102653551B1 (enExample) |
| CN (2) | CN115235841B (enExample) |
| AU (5) | AU2018230514B2 (enExample) |
| BR (1) | BR112019015803B1 (enExample) |
| CA (1) | CA3053184C (enExample) |
| IL (2) | IL282867B (enExample) |
| SG (1) | SG11201906814YA (enExample) |
| TW (2) | TWI755498B (enExample) |
| WO (1) | WO2018165630A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USD246260S (en) * | 1976-02-09 | 1977-11-01 | Lynne Forrester | Hair color applicator |
| WO2019175371A1 (en) * | 2018-03-16 | 2019-09-19 | Inveox Gmbh | Sample processing system and method for automatically processing histological samples |
| USD883515S1 (en) * | 2018-07-11 | 2020-05-05 | Hologic, Inc. | Tube printer |
| USD874017S1 (en) * | 2018-11-02 | 2020-01-28 | Hologic, Inc | Slide imaging system |
| AU2020253774B2 (en) * | 2019-03-29 | 2023-10-05 | Gen-Probe Incorporated | Disposable pipette tip management |
| USD921218S1 (en) | 2019-03-29 | 2021-06-01 | Gen-Probe Incorporated | Pipette tip holder chain link |
| DE102019119500A1 (de) * | 2019-07-18 | 2021-01-21 | Leica Biosystems Nussloch Gmbh | Drucker zum Bedrucken von Histologielabor-Verbrauchsartikeln |
| US11607200B2 (en) * | 2019-08-13 | 2023-03-21 | GE Precision Healthcare LLC | Methods and system for camera-aided ultrasound scan setup and control |
| EP4051622A4 (en) | 2019-10-29 | 2023-12-13 | Beckman Coulter, Inc. | SAMPLE TUBE CUTTER |
| CN113495085B (zh) * | 2020-04-03 | 2023-07-07 | 深圳市帝迈生物技术有限公司 | Poct血细胞分析仪及阻抗检测池的液体流动的驱动装置 |
| US11914131B1 (en) * | 2020-08-16 | 2024-02-27 | Gregory Dimitrenko | Optical testing system for detecting infectious disease, testing device, specimen collector and related methods |
| KR102576041B1 (ko) * | 2021-02-09 | 2023-09-07 | (주)유아이엠디 | 슬라이드 표본의 고배율 이미지 획득방법 |
| CN115970782A (zh) * | 2021-10-14 | 2023-04-18 | 博讯生物科技股份有限公司 | 吸液器的吸管尖连接装置及连接方法 |
| US12360133B2 (en) * | 2021-11-01 | 2025-07-15 | Drsignal Biotechnology Co., Ltd. | Pipette-tip connecting device and method thereof |
| EP4075147B1 (en) * | 2021-11-02 | 2025-01-15 | Drsignal Biotechnology Co., Ltd | Pipette-tip connecting device and method thereof |
| CN114354308B (zh) * | 2021-12-27 | 2024-03-19 | 厦门大学 | 一种全自动制片染色阅片一体机 |
| CN114394310A (zh) * | 2022-01-21 | 2022-04-26 | 中南大学湘雅医院 | 一种分子生物学实验样品储存装置 |
| WO2023201066A1 (en) * | 2022-04-15 | 2023-10-19 | Polybiomics, Inc. | Polybiosensing and imaging platform system, method and device |
| TWI828389B (zh) * | 2022-10-26 | 2024-01-01 | 信任生醫股份有限公司 | 樣本處理模組及包含該樣本處理模組的生物樣本處理設備 |
| CN115926957A (zh) * | 2022-11-01 | 2023-04-07 | 苏州莱博睿思生物科技有限公司 | 一种采集器、细胞分选设备及细胞采集方法 |
| TWI883681B (zh) * | 2023-12-01 | 2025-05-11 | 達易特基因科技股份有限公司 | 生物晶片定量定性分析自動化判讀系統 |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001505648A (ja) * | 1996-07-05 | 2001-04-24 | ベックマン コールター インコーポレイテッド | 自動試料処理システム |
| WO2006075201A1 (en) * | 2004-09-08 | 2006-07-20 | Pfizer Products Inc. | Automated system for handling and weighing analytic quantities of particulate substances |
| JP2009058509A (ja) * | 2007-08-29 | 2009-03-19 | F Hoffmann La Roche Ag | 脱キャップシステム |
| WO2009141957A1 (ja) * | 2008-05-22 | 2009-11-26 | 株式会社日立ハイテクノロジーズ | 検体前処理システム |
| US20100043211A1 (en) * | 2006-12-04 | 2010-02-25 | Inpeco Ip Ltd. | Apparatus for removing caps from tubular containers |
| JP2013003153A (ja) * | 2011-06-20 | 2013-01-07 | F Hoffmann-La Roche Ag | 閉鎖されたサンプル管を処理するシステム |
| JP2014526687A (ja) * | 2011-09-09 | 2014-10-06 | ジェン−プローブ・インコーポレーテッド | 自動試料操作器具、システム、プロセス、及び方法 |
| JP2014210338A (ja) * | 2013-04-19 | 2014-11-13 | メトラー−トレド アクチェンゲゼルシャフト | 回転可能なグリッパを有する試料準備システム |
Family Cites Families (74)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5349479U (enExample) * | 1976-09-30 | 1978-04-26 | ||
| JPS6365370A (ja) * | 1986-09-05 | 1988-03-23 | Nippon Tectron Co Ltd | サンプルピペツト装置 |
| US5166889A (en) * | 1989-01-10 | 1992-11-24 | Medical Robotics, Inc. | Robotic liquid sampling system |
| US5282978A (en) | 1990-07-09 | 1994-02-01 | Cytyc Corporation | Specimen processor method and apparatus |
| US5143627A (en) | 1990-07-09 | 1992-09-01 | Cytyc Corporation | Method and apparatus for preparing cells for examination |
| US5240606A (en) | 1990-07-09 | 1993-08-31 | Cytyc Corporation | Apparatus for preparing cells for examination |
| US5269918A (en) * | 1990-07-09 | 1993-12-14 | Cytyc Corporation | Clinical cartridge apparatus |
| DE29814119U1 (de) * | 1998-08-06 | 1999-02-18 | Brauner, Rainer, 97072 Würzburg | UHV-kompatibler Probenhalter |
| US6572824B1 (en) | 1998-09-18 | 2003-06-03 | Cytyc Corporation | Method and apparatus for preparing cytological specimens |
| US6562299B1 (en) | 1998-09-18 | 2003-05-13 | Cytyc Corporation | Method and apparatus for preparing cytological specimens |
| DE19917646B4 (de) * | 1999-04-19 | 2013-06-20 | Siemens Healthcare Diagnostics Products Gmbh | Verschlußvorrichtung für Reagenzbehälter |
| US6665060B1 (en) | 1999-10-29 | 2003-12-16 | Cytyc Corporation | Cytological imaging system and method |
| US7006674B1 (en) | 1999-10-29 | 2006-02-28 | Cytyc Corporation | Apparatus and methods for verifying the location of areas of interest within a sample in an imaging system |
| FR2810407B1 (fr) * | 2000-06-16 | 2002-08-02 | Philippe Escal | Appareil pour l'analyse d'echantillons |
| WO2002029419A2 (de) * | 2000-10-06 | 2002-04-11 | Chemspeed Ltd. | Vorrichtung mit einem werkzeughalter und einem abnehmbar befestigbaren werkzeug |
| US7771662B2 (en) | 2001-10-19 | 2010-08-10 | Hologic, Inc | Vial system and method for processing liquid-based specimens |
| AU2006235787A1 (en) * | 2001-10-19 | 2006-11-23 | Monogen, Inc | Automated system and method for processing multiple liquid-based specimens |
| JP3694490B2 (ja) * | 2002-03-29 | 2005-09-14 | アロカ株式会社 | 検体前処理システム |
| US7648678B2 (en) * | 2002-12-20 | 2010-01-19 | Dako Denmark A/S | Method and system for pretreatment of tissue slides |
| JP3972012B2 (ja) * | 2003-03-19 | 2007-09-05 | 株式会社日立ハイテクノロジーズ | 試料分注機構及びそれを備えた自動分析装置 |
| ES2220227B1 (es) * | 2003-05-30 | 2006-02-16 | INSTITUTO NACIONAL DE TECNICA AEROESPACIAL "ESTEBAN TERRADAS" | Metodo y aparato para la deteccion de sustancias o analitos a partir del analisis de una o varias muestras. |
| CA2524687C (en) | 2003-06-12 | 2013-03-12 | Cytyc Corporation | System for organizing multiple objects of interest in field of interest |
| ATE355529T1 (de) * | 2003-08-20 | 2006-03-15 | Sysmex Corp | Probenanalysegerät und eine vorrichtung zur detektion von nukleinsäuren |
| US7083106B2 (en) | 2003-09-05 | 2006-08-01 | Cytyc Corporation | Locally storing biological specimen data to a slide |
| US20050100483A1 (en) | 2003-11-12 | 2005-05-12 | Cytyc Corporation | Specimen filter container having data storage |
| US8043562B2 (en) * | 2003-12-08 | 2011-10-25 | Ortho-Clinical Diagnostics, Inc. | Analyzer having removable holders or a centrifuge |
| JP4221349B2 (ja) * | 2004-09-17 | 2009-02-12 | 株式会社日立ハイテクノロジーズ | 自動分析装置 |
| JP3980031B2 (ja) * | 2005-02-09 | 2007-09-19 | 株式会社日立製作所 | 自動分析装置 |
| US7556777B2 (en) | 2005-03-08 | 2009-07-07 | Cytyc Corporation | Specimen vial cap handler and slide labeler |
| US7998751B2 (en) * | 2005-04-26 | 2011-08-16 | Siemens Healthcare Diagnostics Inc. | Method and apparatus for aspirating and dispensing small liquid samples in an automated clinical analyzer |
| US7587078B2 (en) | 2005-05-02 | 2009-09-08 | Cytyc Corporation | Automated image analysis |
| US7686771B2 (en) | 2005-12-12 | 2010-03-30 | Cytyc Corporation | Method and apparatus for obtaining aliquot from liquid-based cytological sample |
| US20070148041A1 (en) | 2005-12-22 | 2007-06-28 | Cytyc Corporation | Systems methods and kits for preparing specimen slides |
| AU2007282135C1 (en) * | 2006-01-18 | 2012-05-24 | Coimmune, Inc. | Systems and methods for processing samples in a closed container, and related devices |
| KR100887590B1 (ko) * | 2006-03-21 | 2009-03-11 | 김일희 | 생물시료 부착장치 |
| EP2021807B1 (en) * | 2006-04-24 | 2013-06-12 | Protedyne Corporation | Robotic system with autonomously operable tools |
| US20080020467A1 (en) * | 2006-07-20 | 2008-01-24 | Lawrence Barnes | Fluid metering in a metering zone |
| US7674434B2 (en) | 2006-11-27 | 2010-03-09 | Cytyc Corporation | Vials and apparatus for obtaining an aliquot of a sample |
| US8119399B2 (en) | 2006-12-13 | 2012-02-21 | Cytyc Corporation | Method and system for collecting cells of a biological specimen |
| US20080145887A1 (en) | 2006-12-19 | 2008-06-19 | Cytyc Corporation | Cytological filter with data storage |
| CN103913585B (zh) * | 2007-03-30 | 2016-08-31 | 希森美康株式会社 | 配液器、配液方法及吸液管 |
| ES2843373T3 (es) * | 2007-04-06 | 2021-07-16 | Becton Dickinson Co | Sistema de preparación de muestras para procesamiento de especímenes clínicos |
| JP4959450B2 (ja) * | 2007-07-10 | 2012-06-20 | 株式会社日立ハイテクノロジーズ | 化学分析装置 |
| CA2692066C (en) * | 2007-07-10 | 2017-03-14 | Ventana Medical Systems, Inc. | Apparatus and method for biological sample processing |
| US8119363B2 (en) | 2008-05-02 | 2012-02-21 | Cellsolutions, Llc | Cell sample preparation method and apparatus |
| US8137642B2 (en) | 2008-06-13 | 2012-03-20 | Cytyc Corporation | Method and apparatus for calibrating filters during specimen collection |
| JP5431755B2 (ja) * | 2008-10-31 | 2014-03-05 | シスメックス株式会社 | 検体分析装置および検体分析方法 |
| AU2010248902B2 (en) * | 2009-05-15 | 2015-02-26 | Biomerieux, Inc. | Automated microbial detection apparatus |
| WO2011002779A2 (en) * | 2009-06-30 | 2011-01-06 | Ventana Medical Systems, Inc. | Methods and apparatuses for applying and removing fluids for processing biological samples |
| US10288632B2 (en) * | 2009-09-21 | 2019-05-14 | Pocared Diagnostics Ltd. | System for conducting the identification of bacteria in biological samples |
| JP5346265B2 (ja) * | 2009-09-30 | 2013-11-20 | シスメックス株式会社 | 検体分析装置および検体分析方法 |
| EP2388561B1 (de) * | 2010-05-20 | 2015-12-02 | Mettler-Toledo AG | Laborgerät zur Probenvorbereitung |
| EP2646792B1 (en) * | 2010-12-01 | 2019-07-10 | President and Fellows of Harvard College | Apparatus and methods for aliquotting frozen samples |
| EP2728362B1 (en) | 2011-06-30 | 2016-03-02 | Hitachi High-Technologies Corporation | Automatic analysis system |
| JP5709678B2 (ja) * | 2011-07-14 | 2015-04-30 | パナソニックヘルスケアホールディングス株式会社 | 分注装置 |
| CN103733072B (zh) | 2011-08-22 | 2016-10-19 | 株式会社日立高新技术 | 栓开闭装置及试样处理装置 |
| GB2495934A (en) * | 2011-10-25 | 2013-05-01 | Tap Biosystems Phc Ltd | Bioreactor outlet air conditioning systems and associated methods |
| FI20116059A7 (fi) * | 2011-10-28 | 2013-04-29 | Thermo Fisher Scientific Oy | Reagenssipullo, järjestelmä, menetelmä ja laite suljinkorkkien ja vastaavien käsittelemiseksi |
| BR112014010955A2 (pt) * | 2011-11-07 | 2017-06-06 | Beckman Coulter Inc | sistema e método para processar amostras |
| DE102011055899B4 (de) * | 2011-11-30 | 2013-11-21 | Andreas Hettich Gmbh & Co. Kg | Verfahren und eine Vorrichtung zum Handhaben von Probenbehältern |
| US9199755B1 (en) * | 2012-02-11 | 2015-12-01 | Joseph Cohen | Apparatus and methods for handling tubes or vials |
| DE102012208707A1 (de) * | 2012-05-24 | 2013-12-12 | Hamilton Bonaduz Ag | Probenverarbeitungssystem zum Verarbeiten von biologischen Proben |
| AU2013337607B2 (en) * | 2012-11-01 | 2017-03-09 | Leica Biosystems Melbourne Pty Ltd | A slide transport system |
| AU2013202805B2 (en) | 2013-03-14 | 2015-07-16 | Gen-Probe Incorporated | System and method for extending the capabilities of a diagnostic analyzer |
| WO2015108164A1 (ja) * | 2014-01-16 | 2015-07-23 | ユニバーサル・バイオ・リサーチ株式会社 | 軟質栓貫通分注装置および軟質栓貫通分注方法 |
| EP3209501B1 (en) | 2014-10-21 | 2023-03-08 | Gen-Probe Incorporated | Method and apparatus for printing on an object having a curved surface |
| JP6535487B2 (ja) * | 2015-03-18 | 2019-06-26 | あおい精機株式会社 | 閉栓装置、閉栓ユニット及び閉栓方法 |
| WO2016191646A2 (en) * | 2015-05-28 | 2016-12-01 | Bd Kiestra B.V. | Automated method and system for obtaining and preparing microorganism sample for both identification and antibiotic susceptibility tests |
| US10094847B2 (en) | 2015-07-31 | 2018-10-09 | Gen-Probe Incorporated | Automated sample processing instruments, systems, processes, and methods |
| WO2017221775A1 (ja) * | 2016-06-21 | 2017-12-28 | コニカミノルタ株式会社 | 反応方法、ならびにこれを行う反応システムおよび反応装置 |
| JP6710850B1 (ja) * | 2017-04-20 | 2020-06-17 | バイオフルイディカ、インコーポレイテッド | 液体サンプルからバイオマーカーを単離するための流体密封性フローシステム |
| CN111247436B (zh) * | 2018-01-26 | 2023-07-28 | 株式会社日立高新技术 | 自动分析装置 |
| EP3620772B1 (en) * | 2018-09-06 | 2021-10-13 | Milestone S.r.l. | System and method for filling a closed container with a fixative solution |
| EP3693745B1 (en) * | 2019-02-07 | 2023-05-17 | Sartorius Biohit Liquid Handling Oy | Tip removal in automated pipette module |
-
2018
- 2018-03-09 KR KR1020227040071A patent/KR102653551B1/ko active Active
- 2018-03-09 KR KR1020227040068A patent/KR102688513B1/ko active Active
- 2018-03-09 KR KR1020227028531A patent/KR102643765B1/ko active Active
- 2018-03-09 BR BR112019015803-0A patent/BR112019015803B1/pt active IP Right Grant
- 2018-03-09 CN CN202210704627.XA patent/CN115235841B/zh active Active
- 2018-03-09 WO PCT/US2018/021879 patent/WO2018165630A1/en not_active Ceased
- 2018-03-09 KR KR1020197025192A patent/KR102248971B1/ko active Active
- 2018-03-09 KR KR1020217012965A patent/KR102435609B1/ko active Active
- 2018-03-09 TW TW107108177A patent/TWI755498B/zh active
- 2018-03-09 AU AU2018230514A patent/AU2018230514B2/en active Active
- 2018-03-09 IL IL282867A patent/IL282867B/en unknown
- 2018-03-09 CA CA3053184A patent/CA3053184C/en active Active
- 2018-03-09 JP JP2019548377A patent/JP6934061B2/ja active Active
- 2018-03-09 US US16/084,955 patent/US10900875B2/en active Active
- 2018-03-09 SG SG11201906814YA patent/SG11201906814YA/en unknown
- 2018-03-09 CN CN201880016720.3A patent/CN110383034B/zh active Active
- 2018-03-09 TW TW111101663A patent/TWI792862B/zh active
-
2019
- 2019-09-05 IL IL269155A patent/IL269155B/en active IP Right Grant
-
2020
- 2020-12-24 US US17/133,690 patent/US11536634B2/en active Active
-
2021
- 2021-03-24 AU AU2021201848A patent/AU2021201848B2/en active Active
- 2021-08-20 JP JP2021134636A patent/JP7258973B2/ja active Active
-
2022
- 2022-08-19 AU AU2022218618A patent/AU2022218618B2/en active Active
- 2022-11-17 US US18/056,680 patent/US12298212B2/en active Active
-
2023
- 2023-04-05 JP JP2023061112A patent/JP7528300B2/ja active Active
- 2023-04-05 JP JP2023061113A patent/JP7512468B2/ja active Active
-
2024
- 2024-06-04 AU AU2024203746A patent/AU2024203746B2/en active Active
- 2024-06-04 AU AU2024203745A patent/AU2024203745B2/en active Active
- 2024-06-26 JP JP2024102631A patent/JP2024153623A/ja active Pending
-
2025
- 2025-01-15 US US19/022,689 patent/US20250155337A1/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001505648A (ja) * | 1996-07-05 | 2001-04-24 | ベックマン コールター インコーポレイテッド | 自動試料処理システム |
| WO2006075201A1 (en) * | 2004-09-08 | 2006-07-20 | Pfizer Products Inc. | Automated system for handling and weighing analytic quantities of particulate substances |
| US20100043211A1 (en) * | 2006-12-04 | 2010-02-25 | Inpeco Ip Ltd. | Apparatus for removing caps from tubular containers |
| JP2009058509A (ja) * | 2007-08-29 | 2009-03-19 | F Hoffmann La Roche Ag | 脱キャップシステム |
| WO2009141957A1 (ja) * | 2008-05-22 | 2009-11-26 | 株式会社日立ハイテクノロジーズ | 検体前処理システム |
| JP2013003153A (ja) * | 2011-06-20 | 2013-01-07 | F Hoffmann-La Roche Ag | 閉鎖されたサンプル管を処理するシステム |
| JP2014526687A (ja) * | 2011-09-09 | 2014-10-06 | ジェン−プローブ・インコーポレーテッド | 自動試料操作器具、システム、プロセス、及び方法 |
| JP2014210338A (ja) * | 2013-04-19 | 2014-11-13 | メトラー−トレド アクチェンゲゼルシャフト | 回転可能なグリッパを有する試料準備システム |
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TWI755498B (zh) | 自動化製備生物樣本之系統及方法 | |
| US12392692B2 (en) | Systems for automated preparation of biological specimens | |
| HK40076921A (en) | Systems and methods for automated preparation of biological specimens | |
| EP3497428B1 (en) | Systems and methods for automated preparation of biological specimens | |
| HK40009379B (en) | Systems and methods for automated preparation of biological specimens | |
| HK40009379A (en) | Systems and methods for automated preparation of biological specimens |